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Chp. 11: Introduction to Genetics 11.1 The Work of Gregor Mendel HW: Read, Quiz Tomorrow 11.2 Probability and Punnett Square A. Punnett Squares – used to predict and compare genetic variations that will result from a cross 1. Homozygous – 2 identical alleles a. Dominant – RR, more likely to be seen b. Recessive – rr, less likely to be seen 2. Heterozygous – 2 diff. alleles, Rr a. Trait is still dom. 3. Phenotype – physical trait you see (brown eyes, green pods) 4. Genotype – genetic makeup (Rr, RR,rr) B. Probability – likelihood that an event will occur 1. Principle of probability predict the outcome of genetic crosses 2. What is the probability that you will flip a coin and land heads up 4x in a row? a. ½ * ½ * ½ * ½= 1/16 C. Probabilities Predict Averages 1. Predicts the average outcome for large events 2. In 100 plants in a Heterozygous Cross 75 will be Tall and 25 will be short 11.3 Exploring Mendelian Genetics A. Independent Assortment 1. The 2 Factor Cross: F1 a. Mendel crossed true breeding plants that produced only round yellow peas. i. Round and Yellow alleles are dominant to wrinkled and green alleles 2. The 2 Factor Cross: F2 a. Mendel took the hybrid plants from F1 and crossed them (all were RrYy) b. Results were in a ratio of 9:3:3:1 3. Independent Assortment - genes from different traits separate independently during the formation of gametes (sex cells) a. Accounts for many genetic variations in plants, animals and other organisms. B. Summary of Mendel’s Principles 1. Inheritance of specific traits is determined by genes. Genes are passed from parents to offspring. 2. Some forms of the gene may be dominant and others may be recessive. 3. In most sexually reproducing organisms, each adult has 2 copies of the gene (1 from each parent). These genes segregate from each other when gametes are formed. 4. Alleles for different genes usually segregate independently of one another. C. Beyond Dominant and Recessive Alleles 1. Some alleles are neither dominant nor recessive; some traits are controlled by multiple alleles or genes. a. Incomplete Dominance – cases in which 1 allele is not completely dominant i. Red (RR) and White (WW) plants crossed to get Pink (RW) b. Codominance – both alleles contribute to the phenotype i. Chicken Feathers a. White-WW b. Black –BB c. Speckled – BW c. Multiple Alleles – some genes have more then 2 alleles i. Rabbits a. 4 possible coat colors ii. Blood Types d. Polygenic Traits – traits controlled by 2 or more genes i. Human Skin Color a. At least 4 different genes control this trait