Download 1-2 Endocrine tissues, hormones and actions 1

General Endocrinology(AP 723)
Faculty of Agriculture
Department of Animal Production
First Semester 2005/2006
Instructor: Dr. Mustafa Beni-Domi
Phone:7201000 Ext. 22221 E-mail: [email protected]
Office hours: (Sun, Mon, Tue & Wed 8:15-9:15) or by an appointment.
Lecture hall:
M2 006 or the Animal Physiology Lab
Lecture time:
9:45 – 11:15 (Mon and Wed)
Course objectives:
1)
Develop student’s knowledge of hormonal actions and regulatory
aspects of the endocrine system.
2)
Relate basic information to applied/clinical endocrinology.
3)
Expose students to current research findings and literature.
What are expected to learn from this course:
This course covers the endocrinology of animals, including man: physiology and
anatomy of the endocrine glands and the biosynthesis and chemistry of
hormones. Upon completion of the course, each student should be able to
discuss the actions of all hypothalamic, pituitary, and reproductive hormones.
Students should be able describe methodologies used in endocrinology and be
able to apply those to various endocrine research approaches. Provide detail
about the pituitary gland and the hormones associated with it. Describe the
class, synthesis, secretion and modes of action of various hormones. Describe
adrenal gland hormones and hormonal control of reproduction for males and
females.
Course Contents:
Week
1-2
3
4
5-6
Subject
Endocrine tissues, hormones and actions
Endocrine hypothalamus
Endocrine methodologies
Pituitary hormones
Reference
1
1
1
1
7
8
9
10
11
12
13
14
15
16
Neurohypophysial hormones
Growth hormones
Thyroid hormones
Adrenal hormones
- Glucocorticoids
- Minralocoticoids
- Catecholamines
Pancreatic hormones
Gastrointestinal hormones
Calcium homeostasis
Male reproductive endocrinology
Female reproductive endocrinology
Pineal gland
1
1
1
1
1
1
1
1
1
1
Lecture text:
1.
Required text: Endocrinology, 5th Edition, Mac E Hadley, Prentice
Hall, 2000.
Grading:
First exam
Second exam
Final exam
Written Comprehensive
Term paper
25% (Wed-November 9, 2005)
25% (Wed-December 7, 2005)
40% to be scheduled
10% (not later than May 9th, 2004)
Notes:
Attendance in class is required. Students are expected to attend class
regularly. Participation in class discussions is strongly encouraged. No make-up
exams unless absence was excused.
The Term Paper
In an effort to provide you the opportunity to learn unique writing and
presentation skills, I have incorporated two different writing assignments in AP
723.
The first writing exercise will be a critique of a journal article relevant and
recent to endocrinology. In this assignment, you shall be given a choice of
recent journal articles and shall select one to evaluate. The article must be
approved by the instructor. The critique will examine both the science and the
presentation of data used by the author(s). Contact me for further information
about this assignment.
The second writing exercise will be a case study or research report in
Veterinary Endocrinology. Organization of your written report should conform
to the following outlines:
First page:
Title of report, your name, course title and number, semester and year.
List which species and endocrine topic (i.e., hypothalamus, pituitary, growth
hormone, prolactin, insulin, ….etc)the report covers.
Abstract: A concise summary (about half page).
Introduction: Describe the situation in general terms. Provide background
information needed to understand the study. What circumstances initiated the
study (about half page)?
Pages 2 to 5:
Symptoms (1/4 to 1/2 page).
Diagnosis. Describe any diagnostic tests that were performed; why were they
performed; test results and their interpretation (1/2 to 1 page).
Therapy: What was the nature of treatment and response (1/4 to 1/2 page).
Endocrine aspects of the case. Describe underlying endocrine physiology (1-2
pages).
Diagrams, illustrations, tables, graphs, pictures etc. Include legends.
List source material (references) used for report as in the Journal of Journal
of Clinical Endocrinology and Metabolism.
Format of the paper:
Double-spaced typed (12 pt font, Arial), 1-inch margins and numbered pages.
Source of material for Vet cases may be found in Vet Medicine Journals,
Journal of Clinical Endocrinology and Metabolism or any other related clinical
reports.
Oral presentations at the end of the semester will be limited to 15-20 minutes.
General Endocrinology(AP 723)
Faculty of Agriculture
Department of Animal Production
First Semester 2001/2002
Instructor: Dr. Mustafa Beni-Domi
Phone:7095111
Ext.
[email protected]
22221
E-mail:
Office hours: (Mon & Wed 10:15-1:15).
Lecture hall: G2 120
Lecture time: 11:15 – 12:15 (Sun, Tue & Thu)
Course objectives:
1)
Develop student’s knowledge of hormonal actions
and regulatory aspects of the endocrine system.
2)
Relate
basic
endocrinology.
information
3)
Expose students
literature.
to
current
to
applied/clinical
research
findings
What are expected to learn from this course:
This
course
covers
the
endocrinology
of
animals,
including man: physiology and anatomy of the endocrine
glands and the biosynthesis and chemistry of hormones.
Students should be able describe methodologies used in
endocrinology and be able to apply those to various
endocrine research approaches. Provide detail about the
pituitary gland and the hormones associated with it.
Describe the class, synthesis, secretion and modes of
action of various hormones. Describe adrenal gland
hormones and hormonal control of reproduction for males
and females.
Course Contents:
Week Subject
Reference
and
1-2
Endocrine tissues, hormones and actions
1
3
Endocrine hypothalamus
1
4
Endocrine methodologies
1
5-6
Pituitary hormones
1
7
Neurohypophysial hormones
1
8
Growth hormones
1
9
10
Thyroid hormones
Adrenal hormones
- Glucocorticoids
- Minralocoticoids
- Catecholamines
1
1
11
Pancreatic hormones
1
12
Gastrointestinal hormones
1
13
Calcium homeostasis
1
14
Male reproductive endocrinology
1
15
Female reproductive endocrinology
1
16
Pineal gland
1
Lecture text:
1.
Required text: Endocrinology,
Hadley, Prentice Hall, 2000
Grading:
First exam
Second exam
Term paper
Final exam
20%
20%
10%
50%
5th
Edition,
Mac
E
(Thursday-November 15th, 2001)
(Thursday-December 20th, 2001)
(Due January 14th, 2001)
(to be scheduled)
Notes:
Attendance in class is required. Students are expected to
attend class regularly. Participation in class discussions is
strongly encouraged. No make-up exams unless absence was
excused.
General Endocrinology (AP 723)
A case study or research report in Vet endocrinology
Organization of your
following outlines:
written
report
should
name,
course
title
First page:
Title of report, your
semester and year.
conform
and
to
number,
List
which
species
and
endocrine
topic
(i.e.,
hypothalamus,
pituitary,
growth
hormone,
prolactin,
insulin, ….etc)the report covers.
Abstract: A concise summary (about half page).
Introduction: Describe the situation in general terms.
Provide background information needed to understand the
study. What circumstances initiated the study (about half
page)?
Pages 2 to 5:
Symptoms (1/4 to 1/2 page).
Diagnosis. Describe any diagnostic
performed; why were they performed;
their interpretation (1/2 to 1 page).
tests that were
test results and
Therapy: What was the nature of treatment and response
(1/4 to 1/2 page).
Endocrine aspects of the case.
endocrine physiology (1-2 pages).
Diagrams, illustrations,
Include legends.
tables,
Describe
graphs,
List source material used for report.
Format of the paper:
underlying
pictures
etc.
the
Typed (12 pt font)
1-inch margins
Double-spaced
Numbered pages
Source material for Vet cases may be found in Vet Medicine
Journals or any other related clinical reports.
LECTURE/DATE
1
Sept
2
3
4
5
6
7
8
9
Oct
2
Introduction - Endocrinology,
Neuroendocrinology, and their
Methods
1-3
6
NO
CLASS
LABOR
DAY
9
Mechanism of Hormone Action Receptors, Steroids & Thyroid Hormones
1-4
13
Mechanism of Hormone Action Peptide, Protein and Neurohormones
1-4,21
16
Hypothalamus / Pituitary Hypophysiotropic Neurohormones
5-6,21
20
Hypothalamus /Anterior Pituitary
- Pituitary Anatomy and Hierarchies
5-6,21
23
Hypothalamus /Posterior Pituitary
- Vasopressin and
Oxytocin
7
27
Intermediary Pituitary and Pineal
- Melanotropins and Melatonin
8,20,21
30
REVIEW - Material from lecture #1
through lecture #7
1-8,20,21
4
EXAM #1 - 25% of final grade
(lectures #1 through #7)
1-8,20,21
10
7
D
11
11
12
13
TOPIC & CHAPTER IN COURSE
TEXTBOOK
14
18
Calcium Regulating Hormones - PTH,
Calcitonin, Vit
9
Gastrointestinal Endocrine System Gastrointestinal
Hormones
10
Pancreas - Insulin and Glucagon
from the Pancreas
11
Growth - Growth Hormones and Growth
Regulators (Growth
Factors)
12
Thyroid - Thyroxine and
Triiodotyronine from the
Thyroid
13
25
Adrenal Gland - Catecholamines and
Adrenal
Medulla
14
28
Steroid Hormones - Adrenal,
Ovarian, and Testicular Steroid
Hormones
15
1
Adrenal Gland - Glucocorticoids and
the Adrenal Cortex 15
4
Adrenal and Kidney - Aldosterone
and the Renin-Angiotensin System
15
8
REVIEW - Material from lecture #10
through lecture #18
8-15,20
11
EXAM #2 - 25% of final grade
(lectures #1 through #18)
1-15,20,21
14
15
16
17
Nov
18
19
20
21
21
22
23
24
25
26
Dec
15
Reproduction - Sexual
Determination, Differentiation and
Development
16
18
Reproduction - Endocrinology of
Male and Female Reproduction
16,17,18
22
Reproduction - Neuroendocrine
Control of Reproductive
Cyclicity
18
29
Reproduction Overview - From
Fertility to Menopause
16-19
2
Course Summary - Neural, Endocrine
and Neuroendocrine
Control
1-21
6
REVIEW - Material from lecture #21
through lecture #25