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Download Vocabulary deletion – inversion – translocation – nondisjunction
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Vocabulary deletion – P. 239 3. Mutations can involve: a) __________ __________________ b) ___________ DNA __________________ inversion – Chromosomal Mutations P. 239 1. 2 ways to have a chromosomal mutation are: a) ____________ in the _____________ of a chromosome b) ______ or _______ of a chromosome translocation – 2. Make sure you wrote complete definitions to the left….REREAD THEM to check for completeness. YOU WILL NEED THEM FOR THE NEXT QUESTION!!! nondisjunction – Use Figure 12-6 and the definitions from this section to identify which type of mutation is affecting the following cells. BEFORE MUTATION: AFTER MUTATION: What is the problem here? ____________________ _________________________________________ Cell 1 ____________________ Type of Mutation Cell 2 ____________________ Type of Mutation Cell 3 ____________________ Type of Mutation Cell 4 ____________________ Type of Mutation What I can’t explain in my own words Vocabulary Use the drawings from the previous page and Figure 12-6 on p. 239 to answer the following questions. 1. Which cell is the only one that is undergoing meiosis? #1 #2 #3 #4 (Circle one) 2. In the cell mentioned in #4 above, one ___________ receives an ____________ ________ of a chromosome, and another _______________ receives ________ ______________. 3. What disorder can a cell like #4 cause? (See Figure 12-7) __________ ________________ 4. Why does the boy in the Figure 12-7 have that disorder? 5. What does this mean? (see Figure 12-7) 6. BONUS – How could this happen? Explain. point mutation – Gene Mutations p. 240 ¶1 – 1. What 3 things cause a point mutation? a. b. c. substitution – 2. A point mutation occurs _________ a ___________ _________ or other ___________ of DNA on a ___________________. 3. If a substitution mutation occurs, can it change the amino acid? YES or NO (circle one) 4. If a substitution mutation occurs, can it affect the protein? YES or NO (circle one) What I can’t explain in my own words Vocabulary p. 240 5. Looking at Figure 12-8, part a, a. What amino acid should be there? _________________ ___________ b. Due to substitution, what amino acid is there? __________________ c. How did that happen? Explain. deletion – (not boldfaced in paragraph) 6. If a base or group of bases is DELETED, what can this loss cause? _________________ ________________ of the remaining ___________ making all the ___________ __________ downstream ___________. 7. What happens to the codons in a frameshift? Circle the correct answer. stay the same or changes the codons after the frameshift mutation or changes the codons before the frameshift mutation frameshift mutation – 8. Is a frameshift dangerous to us? YES or NO (circle one) 9. Explain the answer to #8. 10. In Figure 12-8b, what is causing the frameshift? (compare the “normal” to the “frameshift”) insertion mutation – 11. What type of mutation do you see in Figure 12-8b? deletion or insertion or substitution (Circle one) 12. Which 2 mutations cause a frameshift mutation? substitution or insertion or deletion (Circle two) What I can’t explain in my own words