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BIOLOGY Chapter 11: DNA and the Language of Life Name:________________________ Section Goal: The student will explain how the template mechanism is important in DNA replication and describe the process of DNA replication. Vocabulary: 1. DNA replication 2. DNA polymerase Concept 11.3: DNA replication is the molecular mechanism of inheritance. DNA replication is the process of copying the DNA molecule. During DNA copying, the two strands of the double helix separate. Each single strand acts as a “negative” or “template” for producing a new, complementary strand. A. Easy steps for DNA Replication. Enzymes are protein molecules that catalyze chemical reactions in a cell – usually any protein ending in “ase” is an enzyme 1. DNA replication begins at specific sites called the origins 2. DNA helicase unwinds and separates the two strands of original DNA molecule 3. DNA polymerase 3 adds complementary nucleotides to each separated strand 4. DNA polymerase 1 checks for correct pairing of nucleotides (looks for mutations) and fixes any mispaired nucleotides DNA RNA • Deoxyribose sugar • Ribose sugar • A,T,C,G • A,U,C,G • Double strand • Uracil pairs with adenine • Stays in Nucleus • Single strand • DNA • Nucleus to cytoplasm • Messenger (mRNA), transfer (tRNA), ribosomal (rRNA) Lesson Reflection: Using the following sequences, write the complementary strand of DNA that results after replication. Also, use the base pair cards to match the strand of DNA. 1. DNA molecule #1: TAC/CGG/ATG/CCA/GAT/CAA/ATC Complementary Strand: ______________________________________________________________ 2. DNA molecule #2: TAC/GGG/GGC/GTA/ACC/ACA/ACT Complementary Strand: ______________________________________________________________ 3. DNA molecule #3: TAC/CTG/TTA/AGC/TAC/AAA/ATT Complementary Strand: ______________________________________________________________ 4. DNA molecule #4: TAC/CCC/GGC/AAT/TAC/CGG/GGA Complementary Strand: ______________________________________________________________ Lesson Assessment: 1. Describe how DNA replicates by using a template. 2. Under what circumstances is DNA replicated? Summary of Key concepts: Summary of Key Concepts for 11.3 Technology/Application/Connection to real-world: