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Name_______________________ Miss Badean Mitosis, Meiosis, Mendelian Genetics Practice Questions Date__________ AP Biology ______1. A haploid cell is a cell a. in which the genes are arranged haphazardly. b. containing only one copy of each chromosome. c. that has resulted from the process of mitosis. d. with twice the number of chromosomes of a diploid cell. ______2. The members of a homologous pair of chromosomes a. are identical in size and appearance. b. contain identical genetic information. c. separate to opposite poles of the cell during mitosis. d. are found only in haploid cells. ______3. For a prokaryote cell to divide, which of the following must occur? a. DNA replication, segregation of DNA, and cytokinesis b. DNA replication, crossing over, and segregation of DNA c. DNA replication and segregation of DNA d. A reproductive signal, DNA replication, segregation, and cytokinesis ______4. Bacteria typically have _______, whereas eukaryotes have _______. a. one chromosome that is usually circular; many chromosomes that are linear b. several chromosomes that are circular; many chromosomes that are linear c. one chromosome that is linear; many chromosomes that are circular d. two chromosomes that are usually circular; eight chromosomes that are linear ______5. The products of mitosis are a. one nucleus containing twice as much DNA as the parent nucleus. b. two genetically identical cells. c. four nuclei containing half as much DNA as the parent nucleus. d. four genetically identical nuclei. ______6. . A typical eukaryotic cell cycle consists of a. mitosis and meiosis. b. G1, the S phase, and G2. c. prophase, metaphase, anaphase, and telophase. d. interphase, mitosis, and cytokinesis. 7.–12. Match the eukaryotic cell cycle phase in the list below with the descriptions that follow. Each phase may be used once, more than once, or not at all. a. G1 b. S phase c. G2 d. M phase e. Interphase ______7. Prophase Occurs during this stage ______8. Replication of DNA ______9. Includes the G1 and G2 phases ______10. Segregation of DNA ______11. Cell grows and prepares to replicate the DNA ______12. Results in a human cell containing 92 chromatids ______13. A bacterial cell gives rise to two genetically identical daughter cells by a process known as a. mitosis. b. meiosis. c. binary fission. d. fertilization. ______14. Cells in the intestinal epithelium divide continuously so that cells lost from the surface of the intestinal lining are replaced. A microscopic examination of the live cells would show that most of them a. are in mitosis. b. are in interphase. c. have condensed chromatin (chromosomes). d. Both a and c ______15. During mitosis and meiosis the chromatin condenses. Which of the following processes takes place more easily because of this compaction? a. The orderly distribution of genetic material to two new nuclei b. The replication of the DNA c. Exposing the genetic information on the DNA d. The disappearance of the nuclear membrane ______16. In plant cells, cytokinesis is accomplished by the formation of a(n) a. aster. b. membrane furrow. c. equatorial plate. d. cell plate. ______17. The initiation of the S phase of the cell cycle depends on a pair of molecules called _______ and _______. a. actin; myosin b. Cdk’s; cyclin c. ligand; receptor d. insulin; glucagon ______18. In an organism with a diploid number of 8, a gamete has _______ chromosomes, a liver cell has _______ chromosomes, and a cell undergoing meiosis at meiotic metaphase I has _______ chromosomes. a. 8; 8; 8 b. 4; 4; 8 c. 8; 4; 4 d. 4; 8; 8 ______19. Which of the following statements about sister chromatids is false? a. They arise by replication during S phase. b. They separate from each other during each mitotic anaphase. c. They usually contain identical versions of the same genetic information. d. They separate from each other during meiosis I. ______20. During meiosis I in humans, one of the daughter cells receives a. only maternal chromosomes. b. a mixture of maternal and paternal chromosomes. c. the same number of chromosomes as that of a diploid cell. d. a sister chromatid from each chromosome. ______21. One difference between mitosis and meiosis I is that a. homologous chromosome pairs form tetrads during mitosis. b. chromosomes do not replicate in the interphase preceding meiosis. c. homologous chromosome pairs form tetrads during meiosis but not during mitosis. d. sister chromatids separate during meiosis but not during mitosis. ______22. The exchange of genetic material between chromatids on homologous chromosomes occurs during a. interphase. b. mitosis and meiosis. c. prophase I. d. anaphase I. ______23. The difference between asexual and sexual reproduction is that a. asexual reproduction occurs only in bacteria, whereas sexual reproduction occurs in plants and animals. b. asexual reproduction results from meiosis, whereas sexual reproduction results from mitosis. c. asexual reproduction results in an organism that is identical to the parent, whereas sexual reproduction results in an organism that is not identical to either parent. d. asexual reproduction results from the fusion of two gametes, whereas sexual reproduction produces clones of the parent organism. ______24. Which of the following statements about mitosis is true? a. The chromosome number in the resulting cells is halved. b. DNA replication is completed in prophase. c. Crossing over occurs during prophase. d. Two genetically identical daughter cells are formed. ______25. A diploid human cell normally has 23 pairs of homologous chromosomes, but as a woman ages, the chances of nondisjunction increase. Imagine that a gamete is produced in which the two homologues of chromosome 21 have failed to separate. If one of the produced gametes are fertilized with a normal sperm, the embryo’s cells will contain _______ chromosomes. a. 23 b. 24 c. 46 d. 45 ______26. The fact that most monosomies and trisomies are lethal to human embryos illustrates the a. importance of the orderly distribution of genetic material during meiosis. b. exchange of genetic information during crossing over. c. advantage of sexual reproduction to the survival of a population. d. formation of haploid gametes as a result of meiosis. ______27. Different forms of a gene are called a. traits. b. phenotypes. c. genotypes. d. alleles. ______28. A pea plant with red flowers is test crossed, and one-half of the resulting progeny have red flowers, while the other half has white flowers. Therefore, the genotype of the test-crossed parent was a. RR. b. Rr. c. rr. d. either RR or Rr. ______29. The genotype of an organism that expresses a dominant trait can be determined by a. crossing the organism with a homozygous dominant organism. b. crossing the organism with a heterozygous dominant organism. c. crossing the organism with a homozygous recessive organism. d. observing the genotype of the progeny from any cross. ______30. Classical albinism results from a recessive allele. Which of the following is the expected ratio for the progeny when a normally pigmented male with an albino father has children with an albino woman? a. 3/4 normal, 1/4 albino b. 3/4 albino, 1/4 normal c. 1/2 normal,1/2 albino d. All normal ______31. Which of the following statements about a dihybrid cross is true? a. It results in a genotypic ratio of 2:1. b. It results in offspring of lower quality than that of the parents. c. It results in two different phenotypes in the F2 generation. d. It is a cross between identical double heterozygotes. ______32. Mendel’s dihybrid crosses a. resulted in four different phenotypes. b. led to the formation of the law of independent assortment. c. involved unlinked genes. d. All of the above ______33. In cocker spaniels, black color (B) is dominant over red (b), and solid color (S) is dominant over spotted (s). If the genes are unlinked, and the offspring of BBss and bbss individuals are mated with each other, and then two of the F1 generation are mated with each other, what fraction of the next generation (F2) will be black and spotted? a. 9/16 b. 3/4 c. 3/16 d. 1/16 ______34. Separation of the alleles of a single gene into different gametes is called a. segregation. b. independent assortment. c. heterozygous separation. d. recombination. ______35. The particular allele of a gene that is present in most individuals in nature is referred to as a. dominant. b. recessive. c. epistatic. d. wild type. ______36. Which of the following statements about Mendelian genetics is false? a. Alternative forms of genes are called alleles. b. In any population, only two alleles can exist for a given gene. c. A genotype is a description of an individual’s alleles. d. Individuals with the same phenotype can have different genotypes. ______37. In a species of wild lupine flower, the smooth seed allele (S) is completely dominant over the wrinkled seed allele (s). If the alleles for height are incompletely dominant, such that TT is tall, Tt is intermediate, and tt is short, what will result from crossing a smooth-seeded, short (SStt) plant with a wrinkledseeded, tall (ssTT) plant? a. One-half will be smooth-seeded and intermediate height; one-half will be smooth-seeded and tall. b. All the progeny will be smooth-seeded and tall. c. All the progeny will be smooth-seeded and short. d. All the progeny will be smooth-seeded and intermediate in height. ______38. In Netherlands dwarf rabbits, a gene showing intermediate inheritance produces three phenotypes. Rabbits that are homozygous for one allele are small; individuals that are homozygous for the other allele are deformed and die; heterozygous individuals are dwarf. If two dwarf rabbits are mated, what proportion of their surviving offspring should be dwarf? a. 1/4 b. 1/3 c. 1/2 d. 2/3 ______39. Despite the law of independent assortment, when two loci are on the same chromosome, the phenotypes of the progeny sometimes do not fit the predicted phenotypes. This outcome can be explained by the phenomenon of a. linkage b. inversions. c. chromatid affinities. d. segregation ______40. Very few genes have been located on the Y chromosomes. Y-linked genes include a gene called SRY. A male with this gene will a. usually pass it to his sons, but occasionally also to a daughter. b. only pass the gene to his sons. c. only pass the gene to his daughters. d. only pass the gene to his grandsons. ______41. In humans, spotted teeth are caused by a dominant sex-linked gene. A man with spotted teeth whose father had normal teeth marries a woman with normal teeth. Therefore, a. all of their daughters will have normal teeth. b. all of their daughters will have spotted teeth. c. all of their children will have spotted teeth. d. half of their sons will have spotted teeth. 42.–43. Cleft chin is an X-linked recessive trait. Assume that a man with a cleft chin marries a woman that is heterozygous. ______42. What percent of their female progeny will show the cleft chin trait? a. 0 percent b. 25 percent c. 50 percent d. 100 percent ______43. What percent of their male progeny will show the cleft chin trait? a. 0 percent b. 25 percent c. 50 percent d. 100 percent ______44. After mapping a chromosome, a scientist finds that genes Q and R are twenty units apart, and genes R and S are ten units apart, and genes Q and S are thirty units apart. The sequence on the chromosome would be a. RSQ b. SQR c. QRS ______45. Match the following disorders with the correct pedigree: Sickle cell anemia (recessive, autosomal) Lou Gehrig’s disease (dominant, autosomal) Hemophilia (X-linked recessive) Male Infertility (Y-linked) a. A – Sickle cell; C – Lou Gehrig’s disease; D – hemophilia; B – Male Infertility b. B – Sickle cell; D – Lou Gehrig’s disease; A – hemophilia; C – Male infertility c. C – Sickle cell; D – Lou Gehrig’s disease; B – hemophilia; A – Male Infertility d. B – Sickle cell; C – Lou Gehrig’s disease; A – hemophilia; D – Male Infertility ______46. Imagine that there is a mutation in the cyclin gene such that its gene product is nonfunctional. What kind of effect would this mutation have on a skin cell in the area of a cut? a. Cdk would not be synthesized. b. There would be no effect, because skin cells do not replicate. c. The cell would not be able to enter G1. d. The cell would be unable to reproduce itself. ______47. The 9:3:3:1 ratio is obtained a. through a dihybrid cross in which the genes are linked on the same chromosome. b. through a dihybrid cross in which the genes are on different chromosomes. c. when crossing over occurs. d. in a test cross. ______48. A woman of blood group A has a child with a man of blood group B. The child’s blood is type O. What are the genotypes of the parents? a. Mother: IAIA; father: IBIa b. Mother: IAIO; father: IBIb c. Mother: IAIO; father: IBIO d. Mother: IAIB; father: IBIO ______49. Which statement about linkage of genes is false? a. Genes on the same chromosome are said to be linked. b. Genes on the same chromosome assort independently. c. Crossing over results in recombinant phenotypes. d. Genes on the same chromosome that are far apart have a higher recombination frequency than those that are close together. ______50. Which statement about crossing over is false? a. Crossing over explains why some genes on the same chromosome are not always inherited together. b. Crossing over occurs during mitosis. c. Crossing over results in recombinant chromatids. d. Recombination frequencies may be used to map the order of genes on a chromosome.