Conservation of Brachyury (T) genes in amphioxus and vertebrates
... Smith (1993) in a bold attempt to define a ‘molecular phylotypic stage’ for early vertebrate development, using similarities in expression patterns of several genes. Such conclusions rely on extrapolation, since mouse, Xenopus, chick and zebrafish are all gnathostome (jawed) vertebrates; there are m ...
... Smith (1993) in a bold attempt to define a ‘molecular phylotypic stage’ for early vertebrate development, using similarities in expression patterns of several genes. Such conclusions rely on extrapolation, since mouse, Xenopus, chick and zebrafish are all gnathostome (jawed) vertebrates; there are m ...
Updated slides on gene prediction
... • Systematically deleted nucleotides from DNA – Single and double deletions dramatically altered protein product – Effects of triple deletions were minor – Conclusion: every triplet of nucleotides, each codon, codes for exactly one amino acid in a protein ...
... • Systematically deleted nucleotides from DNA – Single and double deletions dramatically altered protein product – Effects of triple deletions were minor – Conclusion: every triplet of nucleotides, each codon, codes for exactly one amino acid in a protein ...
Gene Section BAX (BCL2-associated X protein) Atlas of Genetics and Cytogenetics
... BAX-alpha. It was the first death-inducing member of the BCL2 family to be identified, and it was detected as a protein co-purified with BCL2 in immunoprecipitation studies. The BH3 domain of BAX is essential for its homodimerization and its heterodimerization with BCL2 and BCL-XL. Furthermore, the ...
... BAX-alpha. It was the first death-inducing member of the BCL2 family to be identified, and it was detected as a protein co-purified with BCL2 in immunoprecipitation studies. The BH3 domain of BAX is essential for its homodimerization and its heterodimerization with BCL2 and BCL-XL. Furthermore, the ...
Title Slide
... Reminder: Why not measure AVP directly? • AVP is very unstable in plasma even at -20 °C storage (sample transport frozen or blood collection directly in the lab) • AVP is largely attached to platelets • AVP assays performed with the required accuracy are available in only a few selected laboratorie ...
... Reminder: Why not measure AVP directly? • AVP is very unstable in plasma even at -20 °C storage (sample transport frozen or blood collection directly in the lab) • AVP is largely attached to platelets • AVP assays performed with the required accuracy are available in only a few selected laboratorie ...
jxb.oxfordjournals.org - Oxford Academic
... factors used for evaluating rice grain quality (Fitzgerald et al., 2009; Jeon et al., 2010). However, how these genes are regulated during rice seed development remains poorly understood. The rice Wx gene encodes the OsGBSSI, a key enzyme for amylose synthesis in rice endosperm; wx mutants almost ...
... factors used for evaluating rice grain quality (Fitzgerald et al., 2009; Jeon et al., 2010). However, how these genes are regulated during rice seed development remains poorly understood. The rice Wx gene encodes the OsGBSSI, a key enzyme for amylose synthesis in rice endosperm; wx mutants almost ...
Epigenetics & Chromatin Xist through transcriptional control of Dnmt3a
... chromosome from which it is transcribed. Xist RNA is thought to recruit silencing factors that modify the chromatin, bringing about a mitotically stable heterochromatic configuration that can be propagated through subsequent cell divisions (reviewed in [2]). Establishing appropriate X inactivation p ...
... chromosome from which it is transcribed. Xist RNA is thought to recruit silencing factors that modify the chromatin, bringing about a mitotically stable heterochromatic configuration that can be propagated through subsequent cell divisions (reviewed in [2]). Establishing appropriate X inactivation p ...
Creating conditional dual fluorescence labelled transgenic animals
... critical to the field. We developed a fast and straightforward method to determine ncRNAtransgene copy number, orientation, and insertion site in the genome. Furthermore, upon tissuespecific expression of ncRNA, a Cre-loxP mediated dual-fluorescence expression system facilitates fluorescence signal ...
... critical to the field. We developed a fast and straightforward method to determine ncRNAtransgene copy number, orientation, and insertion site in the genome. Furthermore, upon tissuespecific expression of ncRNA, a Cre-loxP mediated dual-fluorescence expression system facilitates fluorescence signal ...
Control of GL2 expression in Arabidopsis leaves and trichomes
... • Because both GL1 and R are required to ectopically activate GL2, it is possible that GL1 and R function as a complex • A construct containing the GL1 gene with a myc epitope as an Nterminal fusion was generated – This same epitope fusion was made to a truncated version of the GL1 protein that expr ...
... • Because both GL1 and R are required to ectopically activate GL2, it is possible that GL1 and R function as a complex • A construct containing the GL1 gene with a myc epitope as an Nterminal fusion was generated – This same epitope fusion was made to a truncated version of the GL1 protein that expr ...
Slide 1
... Use either this parameter or blastResult_url parameter as input but not both together. blastResult_url: url of the blast result. .[BLAST_report]. oldRefFile_direct_data: old blast result file..[BLAST_report]. Use either this parameter or oldblastResult_url as input but not both together. oldRefFile_ ...
... Use either this parameter or blastResult_url parameter as input but not both together. blastResult_url: url of the blast result. .[BLAST_report]. oldRefFile_direct_data: old blast result file..[BLAST_report]. Use either this parameter or oldblastResult_url as input but not both together. oldRefFile_ ...
A natural recessive resistance gene against potato virus
... We show here that the pvr2 locus in pepper, conferring recessive resistance against strains of potato virus Y (PVY), corresponds to a eukaryotic initiation factor 4E (eIF4E) gene. RFLP analysis on the PVY-susceptible and resistant pepper cultivars, using an eIF4E cDNA from tobacco as probe, revealed ...
... We show here that the pvr2 locus in pepper, conferring recessive resistance against strains of potato virus Y (PVY), corresponds to a eukaryotic initiation factor 4E (eIF4E) gene. RFLP analysis on the PVY-susceptible and resistant pepper cultivars, using an eIF4E cDNA from tobacco as probe, revealed ...
The trp Operon - aandersonbiology
... 2. Write a definition or description for each of the gene expression terms in the table on the student answer page. 3. Obtain the components needed to prepare an operon model from your teacher. 4. Construct a model of an operon: a. Obtain a flexible neck straw and a larger straw. b. Place your flexi ...
... 2. Write a definition or description for each of the gene expression terms in the table on the student answer page. 3. Obtain the components needed to prepare an operon model from your teacher. 4. Construct a model of an operon: a. Obtain a flexible neck straw and a larger straw. b. Place your flexi ...
DnaJ-related protein essential for placentation - Development
... expressed on the basal surface of the chorion (Gurtner et al., 1995; Kwee et al., 1995; Yang et al., 1995). Deficiencies in either VCAM1 or α4 integrin result in failure of chorioallantoic fusion in mice (Gurtner et al., 1995; Kwee et al., 1995; Yang et al., 1995). However, this phenotype occurs in ...
... expressed on the basal surface of the chorion (Gurtner et al., 1995; Kwee et al., 1995; Yang et al., 1995). Deficiencies in either VCAM1 or α4 integrin result in failure of chorioallantoic fusion in mice (Gurtner et al., 1995; Kwee et al., 1995; Yang et al., 1995). However, this phenotype occurs in ...
Definition of historical models of gene function and their relation to
... scientists during the research process and do therefore not so often become noticeable in the literature. Accordingly the structure as well as the conceptual meaning of the model can be altered. If the revised model, although similar to its predecessor, replaces it the old model will be regarded out ...
... scientists during the research process and do therefore not so often become noticeable in the literature. Accordingly the structure as well as the conceptual meaning of the model can be altered. If the revised model, although similar to its predecessor, replaces it the old model will be regarded out ...
Disclosure All authors have no competing financial relationships to
... TLR7 in PBMCs, resulting in a trend of decreased downstream production of type I IFNs; whereas inhibition of miR-3148 has an opposite effect. ...
... TLR7 in PBMCs, resulting in a trend of decreased downstream production of type I IFNs; whereas inhibition of miR-3148 has an opposite effect. ...
MEF2 activity during embryogenesis - Development
... muscle fibers. Whether, this transgene is being expressed in a fiber-type-specific manner is currently under investigation. MEF2C transcripts are also expressed in vascular smooth muscle cells throughout development (Edmondson et al., 1994; Lin et al., 1998). Expression of des-MEF2-lacZ was detected ...
... muscle fibers. Whether, this transgene is being expressed in a fiber-type-specific manner is currently under investigation. MEF2C transcripts are also expressed in vascular smooth muscle cells throughout development (Edmondson et al., 1994; Lin et al., 1998). Expression of des-MEF2-lacZ was detected ...
Clustering of mandibular organ-inhibiting hormone and moult
... directly or following sub-cloning into Bluescript vector) by using M13 forward and reverse primers, together with gene-specific primers. In addition, the sequence of continuous regions of 8.5 kb from a representative group 1 clone (l1) and 4.3 kb from a representative group 4 clone (l12) were determ ...
... directly or following sub-cloning into Bluescript vector) by using M13 forward and reverse primers, together with gene-specific primers. In addition, the sequence of continuous regions of 8.5 kb from a representative group 1 clone (l1) and 4.3 kb from a representative group 4 clone (l12) were determ ...
Genotype–phenotype correlations in nemaline myopathy caused by
... clinical details were not available on all patients. Thus, for the separate items, the number of patients in the relevant age group for whom data were known is indicated. For example, children who died before they had reached the age at which they would normally have walked are not included in the n ...
... clinical details were not available on all patients. Thus, for the separate items, the number of patients in the relevant age group for whom data were known is indicated. For example, children who died before they had reached the age at which they would normally have walked are not included in the n ...
Leukaemia Section MLL amplification in leukemia Atlas of Genetics and Cytogenetics
... result of the increase copy number of MLL (gain of function). Moreover, the amplified region is not limited to the MLL/11q23.3 gene locus, and other genes in the MLL flanking region have been also amplified. FISH and other molecular techniques have identified genes at 11q such as DDX6, GAB2, ETS1, F ...
... result of the increase copy number of MLL (gain of function). Moreover, the amplified region is not limited to the MLL/11q23.3 gene locus, and other genes in the MLL flanking region have been also amplified. FISH and other molecular techniques have identified genes at 11q such as DDX6, GAB2, ETS1, F ...
General remarks: A biodesign is a man made, mostly computer
... situation with ATG the customer agrees that in case the sequence design of a DNA/gene construction was performed by the customer or his co-workers himself or in his project responsibility with collaborating parties (like this is the case with funded projects); the customer himself is in full respons ...
... situation with ATG the customer agrees that in case the sequence design of a DNA/gene construction was performed by the customer or his co-workers himself or in his project responsibility with collaborating parties (like this is the case with funded projects); the customer himself is in full respons ...
Pitx1 and Pitx2 are required for development of hindlimb buds
... and Pitx2 genes, Pitx1+/– mice were crossed with mice carrying either a hypomorphic (neo) or null allele of the Pitx2 gene (Fig. 1A) (Gage et al., 1999). To obtain double mutant mice, we crossed Pitx1+/– mice with Pitx2+/– mice. Surprisingly, we did not get the expected Mendelien ratio of 25% double ...
... and Pitx2 genes, Pitx1+/– mice were crossed with mice carrying either a hypomorphic (neo) or null allele of the Pitx2 gene (Fig. 1A) (Gage et al., 1999). To obtain double mutant mice, we crossed Pitx1+/– mice with Pitx2+/– mice. Surprisingly, we did not get the expected Mendelien ratio of 25% double ...
Triple-hit lymphoma
... We report a case of a triple-hit lymphoma in a 72-year-old man. This lymphoma was diagnosed using morphology, flow cytometry, immunochemistry, and cytogenetics. Since many triple-hit lymphomas have not been documented in the literature, it is important to bring attention to this entity, as this lymp ...
... We report a case of a triple-hit lymphoma in a 72-year-old man. This lymphoma was diagnosed using morphology, flow cytometry, immunochemistry, and cytogenetics. Since many triple-hit lymphomas have not been documented in the literature, it is important to bring attention to this entity, as this lymp ...
Multiple Avirulence Loci and Allele-Specific Effector
... natural isolates during transient expression assays of several Pm3 alleles. Further investigation of interallele interactions revealed that the resistance mediated by the Pm3a/f alleles is suppressed by the Pm3b/c alleles, which suggests a complex mechanism underlying allelic race specificity (Stirnw ...
... natural isolates during transient expression assays of several Pm3 alleles. Further investigation of interallele interactions revealed that the resistance mediated by the Pm3a/f alleles is suppressed by the Pm3b/c alleles, which suggests a complex mechanism underlying allelic race specificity (Stirnw ...
MAGMA manual (version 1.06)
... MAGMA detects a header in the file it will look for SNP IDs and p-values in the SNP and P column respectively. If no header is found it will use the first column for SNP IDs and the second column for p-values. If you want to use different columns instead, you can add the use modifier (with two value ...
... MAGMA detects a header in the file it will look for SNP IDs and p-values in the SNP and P column respectively. If no header is found it will use the first column for SNP IDs and the second column for p-values. If you want to use different columns instead, you can add the use modifier (with two value ...