THE RESPONSE TO ARTIFICIAL SELECTION DUE TO
... In addition to the total response estimated in each instance from 1000 replicate computer runs, the following variables have been simultaneously recorded: ;).qO, the initial rate of change in gene frequency per generation, estimated as the mean over the first five generations of selection; (2) L50 a ...
... In addition to the total response estimated in each instance from 1000 replicate computer runs, the following variables have been simultaneously recorded: ;).qO, the initial rate of change in gene frequency per generation, estimated as the mean over the first five generations of selection; (2) L50 a ...
1 Genetic constitution of a population
... sampling variation between successive generations, and the smaller the number of parents the greater is the sampling variation. The effects of sampling variation will be considered in Chapters 3-5, and meantime we shall exclude it from the discussion by supposing always that we are dealing with a 'l ...
... sampling variation between successive generations, and the smaller the number of parents the greater is the sampling variation. The effects of sampling variation will be considered in Chapters 3-5, and meantime we shall exclude it from the discussion by supposing always that we are dealing with a 'l ...
hindlimb - bthsresearch
... engineered to express a gene of interest • The embryo can then be injected with the virus at an early stage • As virus spreads through the developing tissue, gene expression is turned on • In this way we can express genes ectopically in chick tissue – Like a gain of function mutation in a mouse, but ...
... engineered to express a gene of interest • The embryo can then be injected with the virus at an early stage • As virus spreads through the developing tissue, gene expression is turned on • In this way we can express genes ectopically in chick tissue – Like a gain of function mutation in a mouse, but ...
The role of free radicals and antioxidants in
... is accompanied by a significant disruption of the prooxidant and antioxidant balance. Oxidative stress may also have a role in patients with recurrent abortions with no known etiology [18]. During pregnancy, there is an increased number of polymorphonuclear leucocytes (PMNL) that may result in incre ...
... is accompanied by a significant disruption of the prooxidant and antioxidant balance. Oxidative stress may also have a role in patients with recurrent abortions with no known etiology [18]. During pregnancy, there is an increased number of polymorphonuclear leucocytes (PMNL) that may result in incre ...
Solid Tumour Section Esophagus: Barrett's esophagus, dysplasia and adenocarcinoma
... LOH of 5q has been reported as a higher occurrence in high-grade dysplasia and adenocarcinomas of the esophagus. Hypermethylation of the APC gene has been found in 68-100% of Barrett's adenocarcinomas and approximately 50% of Barrett's esophagus. More importantly, hypermethylation of APC with other ...
... LOH of 5q has been reported as a higher occurrence in high-grade dysplasia and adenocarcinomas of the esophagus. Hypermethylation of the APC gene has been found in 68-100% of Barrett's adenocarcinomas and approximately 50% of Barrett's esophagus. More importantly, hypermethylation of APC with other ...
Perspectives in Diabetes Glucokinase Gene Structure
... glucokinase isoforms are generated through alternate splic- acids in a region of the protein situated between the putative ing of the glucokinase gene product. One of these isoforms ATP- and glucose-binding domains. There is no evidence is specific for the liver, whereas two others are specific for ...
... glucokinase isoforms are generated through alternate splic- acids in a region of the protein situated between the putative ing of the glucokinase gene product. One of these isoforms ATP- and glucose-binding domains. There is no evidence is specific for the liver, whereas two others are specific for ...
Full Text - Archives of Pediatric Infectious Diseases
... which stands for New Delhi metallo-beta-lactamase-1. NDM-1 producing bacteria are resistant to nearly all antibiotics, including carbapenem antibiotics which are also known as antibiotics of the last resort. Because, NDM-1 gene makes the bacterium produce an enzyme which neutralizes the activity of ...
... which stands for New Delhi metallo-beta-lactamase-1. NDM-1 producing bacteria are resistant to nearly all antibiotics, including carbapenem antibiotics which are also known as antibiotics of the last resort. Because, NDM-1 gene makes the bacterium produce an enzyme which neutralizes the activity of ...
Role of Hereditary Factors in Weight Loss and Its
... studies conducted in monozygotic twins, i.e. individuals who possess identical genes (Bouchard et al. 1994, Hainer et al. 2000a). A study of Bouchard et al. (1994) described weight loss of slightly overweight identical twins in response to a negative energy balance induced by enhanced physical activ ...
... studies conducted in monozygotic twins, i.e. individuals who possess identical genes (Bouchard et al. 1994, Hainer et al. 2000a). A study of Bouchard et al. (1994) described weight loss of slightly overweight identical twins in response to a negative energy balance induced by enhanced physical activ ...
MCScanX`s manual
... The xyz.gff file can be generated by parsing the .gff3 file released by the sequencing initiatives. Repeat of the same gene is not allowed in the .gff file. When comparing multiple genomes, simply concatenate all inter-/intra-species m8 blast output into xyz .blast file and concatenate all gene posi ...
... The xyz.gff file can be generated by parsing the .gff3 file released by the sequencing initiatives. Repeat of the same gene is not allowed in the .gff file. When comparing multiple genomes, simply concatenate all inter-/intra-species m8 blast output into xyz .blast file and concatenate all gene posi ...
Assaying … promoter activity
... true breeding experiment. In this experiment, recombinant cells were grown at the non-permissive temperature in the absence of antibiotic selection for approximately 10 generations. Following this period, aliquots from this culture were plated onto selective (LB with 5 mg/L gentamicin) or non-select ...
... true breeding experiment. In this experiment, recombinant cells were grown at the non-permissive temperature in the absence of antibiotic selection for approximately 10 generations. Following this period, aliquots from this culture were plated onto selective (LB with 5 mg/L gentamicin) or non-select ...
Altered cellular proliferation and mesoderm
... In Drosophila, the complex pattern of homeotic gene (HOMC) expression is established early in development by the transiently expressed maternal and segmentation genes (Ingham, 1988). Late in development, two groups of genes are necessary to maintain the expression pattern of the homeotic genes. The ...
... In Drosophila, the complex pattern of homeotic gene (HOMC) expression is established early in development by the transiently expressed maternal and segmentation genes (Ingham, 1988). Late in development, two groups of genes are necessary to maintain the expression pattern of the homeotic genes. The ...
Spinal Muscular Atrophy
... SMA has a continuous spectrum of symptoms that ranges from very severe to mild across the four classifications of SMA types SMA experts recommend that medical care for patients should be tailored to their current level of function. Please see for more information the Consensus Statement for Standard ...
... SMA has a continuous spectrum of symptoms that ranges from very severe to mild across the four classifications of SMA types SMA experts recommend that medical care for patients should be tailored to their current level of function. Please see for more information the Consensus Statement for Standard ...
Transcriptional Regulation by FOXP1, FOXP2, and
... the FOXP gene subfamily of transcription factors involved in the development of the central nervous system. Previous studies have shown that the transcriptional activity of FOXP1/2/4 is regulated by homo- and heterodimerization. However, their transcriptional gene targets in the developing brain are ...
... the FOXP gene subfamily of transcription factors involved in the development of the central nervous system. Previous studies have shown that the transcriptional activity of FOXP1/2/4 is regulated by homo- and heterodimerization. However, their transcriptional gene targets in the developing brain are ...
Aus dem Max-Planck-Institut für Psychiatrie
... biochemistry to global behavior. In mice and men, the sympathetic nervous system and the hypothalamic-pituitary-adrenocortical (HPA) system are the central regulators of the stress response (de Kloet et al., 2005). The HPA axis is formed by three main structures: the hypothalamus, the pituitary and ...
... biochemistry to global behavior. In mice and men, the sympathetic nervous system and the hypothalamic-pituitary-adrenocortical (HPA) system are the central regulators of the stress response (de Kloet et al., 2005). The HPA axis is formed by three main structures: the hypothalamus, the pituitary and ...
PDF
... INTRODUCTION Cholesterol, an essential component of eukaryotic cell membranes, also serves as the precursor of many steroid hormones and thus plays vital roles in many developmental processes (Farese and Herz, 1998). Cells in the body maintain proper cholesterol levels through elegant homeostatic re ...
... INTRODUCTION Cholesterol, an essential component of eukaryotic cell membranes, also serves as the precursor of many steroid hormones and thus plays vital roles in many developmental processes (Farese and Herz, 1998). Cells in the body maintain proper cholesterol levels through elegant homeostatic re ...
Efficiency of gene silencing in Arabidopsis
... and homologous inverted repeat (hIR) vectors. hIR constructs carry self-complementary intron-spliced fragments of the target gene whereas transitive vectors have the target sequence fragment adjacent to an intron-spliced, inverted repeat of heterologous origin. Both transitive and hIR constructs fac ...
... and homologous inverted repeat (hIR) vectors. hIR constructs carry self-complementary intron-spliced fragments of the target gene whereas transitive vectors have the target sequence fragment adjacent to an intron-spliced, inverted repeat of heterologous origin. Both transitive and hIR constructs fac ...
Ambiguity aversion and familiarity bias
... helical molecule. There are an estimated 25,000 genes distributed on the 23 pairs of chromosomes. Individuals inherit half of their DNA from each parent. Some genes have various forms, known as alleles representing variations in the sequence of the DNA bases. For example, sickle cell anemia results ...
... helical molecule. There are an estimated 25,000 genes distributed on the 23 pairs of chromosomes. Individuals inherit half of their DNA from each parent. Some genes have various forms, known as alleles representing variations in the sequence of the DNA bases. For example, sickle cell anemia results ...
Using Transcriptional Control To Increase Titers of Secreted
... acterial heterologous protein production is a bedrock of modern molecular biology. A gene that codes for a protein of interest can be inserted into a bacterial cell, often Escherichia coli, and the cell is able to produce the desired protein. Bacteria are the preferred organisms for many heterologou ...
... acterial heterologous protein production is a bedrock of modern molecular biology. A gene that codes for a protein of interest can be inserted into a bacterial cell, often Escherichia coli, and the cell is able to produce the desired protein. Bacteria are the preferred organisms for many heterologou ...
This document has been downloaded from Tampub – The
... are produced by two genes, with SREBF-1a and -1c transcribed from a single gene by alternative promoter use and splicing, and SREBF-2 from a separate gene [2]. There is considerable evidence suggesting that SREBF-2 is closely associated with cholesterol metabolism, while SREBF-1 is more associated w ...
... are produced by two genes, with SREBF-1a and -1c transcribed from a single gene by alternative promoter use and splicing, and SREBF-2 from a separate gene [2]. There is considerable evidence suggesting that SREBF-2 is closely associated with cholesterol metabolism, while SREBF-1 is more associated w ...
Molecular basis of the inflammatory response to adenovirus
... consistent with the studies by Hidaka et al,30 who demonstrated a saturation effect related to adenovirus vector titer and binding in CAR-expressing A549 cells. Cell type and high-affinity receptor density are likely factors that determine at which titer vector saturation occurs. These observations ...
... consistent with the studies by Hidaka et al,30 who demonstrated a saturation effect related to adenovirus vector titer and binding in CAR-expressing A549 cells. Cell type and high-affinity receptor density are likely factors that determine at which titer vector saturation occurs. These observations ...
Molecular Analysis of the Coprinus cinereus Mating Type A Factor
... Classical genetic investigations provided a framework for understanding mechanisms for generating that variation andforthe function of C. cinereus mating type genes. T w o unlinked factors, A and B , control mating and for a completely compatible mating, genetically different A and B factorsmust be ...
... Classical genetic investigations provided a framework for understanding mechanisms for generating that variation andforthe function of C. cinereus mating type genes. T w o unlinked factors, A and B , control mating and for a completely compatible mating, genetically different A and B factorsmust be ...
Synonymous Codon Usage, Accuracy of Translation, and Gene
... shows that the regression line is above the first diagonal line, which means that Fop is significantly higher for constrained codons than for nonconstrained ones. The frequency of optimal codons is about 0.048 (12%) higher at constrained codons than at nonconstrained ones. However, amino acid compos ...
... shows that the regression line is above the first diagonal line, which means that Fop is significantly higher for constrained codons than for nonconstrained ones. The frequency of optimal codons is about 0.048 (12%) higher at constrained codons than at nonconstrained ones. However, amino acid compos ...
Identification of genes involved in the same
... higher-level interaction networks. Complex interactions of cellular functions can be viewed as interaction networks of simpler subunits and functional modules (Friedman, 2004; Kholodenko et al., 2002; Petti and Church, 2005). The technology most prevalent in the study of genetic functional modules i ...
... higher-level interaction networks. Complex interactions of cellular functions can be viewed as interaction networks of simpler subunits and functional modules (Friedman, 2004; Kholodenko et al., 2002; Petti and Church, 2005). The technology most prevalent in the study of genetic functional modules i ...
Mechanisms and constraints shaping the evolution of body plan
... the evolution of a particular phenotype, i.e. a segmented body plan. Thus, to ensure the evolution of these phenotypes we select for them, making the fitness of our in silico organisms depend on the number and pattern of body segments generated. As a consequence, the fact that segmentation evolves in ...
... the evolution of a particular phenotype, i.e. a segmented body plan. Thus, to ensure the evolution of these phenotypes we select for them, making the fitness of our in silico organisms depend on the number and pattern of body segments generated. As a consequence, the fact that segmentation evolves in ...
Primary cilia in energy balance signaling and
... Moreover, metabolic disorders are interrelated diseases exemplified by the association of obesity with insulin resistance, leading to development of type II diabetes (2). Genetic factors for obesity are poorly understood, and recent progress by genome-wide association studies support the notion of p ...
... Moreover, metabolic disorders are interrelated diseases exemplified by the association of obesity with insulin resistance, leading to development of type II diabetes (2). Genetic factors for obesity are poorly understood, and recent progress by genome-wide association studies support the notion of p ...