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Article The Pseudoautosomal Regions of the U/V Sex
Article The Pseudoautosomal Regions of the U/V Sex

... due to their being genetically linked to the nonrecombining, sex-determining region. This phenomenon is expected to occur in both diploid (XY, ZW) and haploid (UV) sexual systems, with slightly different consequences for UV sexual systems because of the absence of masking during the haploid phase (w ...
Special Report on Genetics and: Gout 23 Selected Articles From 199
Special Report on Genetics and: Gout 23 Selected Articles From 199

... * Ctrl+Click on the blue hyperlinks to see the full citations in PubMed®; any articles marked as "Free" can be downloaded in PDF format by following the link provided there. This listing is a selected subset of those found on PubMed® with emphasis on the interplay between genetics and the environmen ...
Integrated analysis of whole-exome sequencing and transcriptome
Integrated analysis of whole-exome sequencing and transcriptome

... Background: Autism spectrum disorders (ASD) are a group of neurodevelopmental disorders with high heritability. Recent findings support a highly heterogeneous and complex genetic etiology including rare de novo and inherited mutations or chromosomal rearrangements as well as double or multiple hits. ...
Hemoglobin A2: origin, evolution, and aftermath
Hemoglobin A2: origin, evolution, and aftermath

... of maturity. These experiments showed that there was a progressive decrease in &-globin synthesis in relation to P-globin in increasingly mature cells. A relative instability of 8-globin mRNA was proposed as a mechanism for the premature decrease in &globin synthesis? Using highly selective probes f ...
Controlling morpholino experiments: don`t stop making antisense
Controlling morpholino experiments: don`t stop making antisense

... they do not carry a negatively charged backbone means that they are less likely to interact non-specifically with other components of the cell and may be less toxic as a result. MOs do not act through an RNaseH mechanism but instead can be designed to inhibit translation (Summerton, 1999) (Fig. 2A), ...
Novel regulatio pendage transformation
Novel regulatio pendage transformation

... EN and INV. Partial cDNAs of two engrailed-class genes have been cloned from P. scaber, both of them contain the epitope and are expressed in coinciding patterns (A. A. and T. C. K., unpublished). The EN expression pattern is similar to that observed in insects and other crustaceans at the segmented ...
Table S1.
Table S1.

... Atlas 2, averaged over all tissues (A) resp. for interesting groups of cells (X according to “categ” column in ...
A nested deletion approach to generate Cre deleter mice with
A nested deletion approach to generate Cre deleter mice with

... given transgene at the desired time and position, or alternatively, to inactivate a gene, or group of genes, only in those organs where one would like to study the phenotype. Therefore, this system helps to overcome the difficulties often created by early lethal conditions, due either to particular ...
Brassinosteroid-6-Oxidases from Arabidopsis and
Brassinosteroid-6-Oxidases from Arabidopsis and

... The tomato Dwarf gene was isolated by transposon tagging (Bishop et al., 1996) and shown to encode a cytochrome P450 enzyme that converts 6-DeoxoCS to CS via 6-OHCS, a step where the early C-6 oxidation and the late C-6 oxidation pathways are connected (Bishop et al., 1999). This step is the furthes ...
- Iranian Journal of Basic Medical Sciences
- Iranian Journal of Basic Medical Sciences

... encodes enzyme catalase-peroxidase and mutation in this gene decreases or blocks the enzyme activity. Mutation in the katG gene is the main mechanism of INH-resistance in most strains (11). There are various methods for detection of INH-resistant M. tuberculosis strains including conventional and mo ...
Genome-Wide Analysis of In Vivo Binding of the Master Regulator
Genome-Wide Analysis of In Vivo Binding of the Master Regulator

... growth-phase dependent manner [7]. A pivotal question to address is how primary environmental signals are relayed to global carbon and nitrogen control and further to the control of development and antibiotic production. The elucidation of the S. coelicolor genome sequence— the first from an antibio ...
The Stress Responses of Probiotic Lactobacilli and a
The Stress Responses of Probiotic Lactobacilli and a

... respectively. The clpL2 region was found to be mobilized after prolonged cultivation of E-97800 at a high temperature. The sequence analyses revealed that clpL2 shared 98 % identity to L. plantarum clpL gene and the clpL2 is flanked by inverted repeat highly identical to the repeats of a functional ...
ABO Blood Group System
ABO Blood Group System

... The ABO Blood Group System was the first to be identified and is the most significant for transfusion practice It is the ONLY system that the reciprocal antibodies are consistently and predictably present in the sera of people who have had no exposure to human red cells ...
Gene Section KLK4 (kallikrein-related peptidase 4) Atlas of Genetics and Cytogenetics
Gene Section KLK4 (kallikrein-related peptidase 4) Atlas of Genetics and Cytogenetics

... Further, in mice, KLK4 was only expressed by transition and maturation stage ameloblasts, which is consistent with KLK4 functioning primarily to degrade the enamel matrix in developing teeth. The role of KLK4 in the prostate, a tissue that highly expresses KLK4, is less clearly defined although it i ...
Document
Document

... The ABO Blood Group System was the first to be identified and is the most significant for transfusion practice It is the ONLY system that the reciprocal antibodies are consistently and predictably present in the sera of people who have had no exposure to human red cells ...
asense is a Drosophila neural precursor gene and is
asense is a Drosophila neural precursor gene and is

... trulation in the nuclei of single cells that are in the process of segregating from the neuroectodermal epithelium, but not in the surrounding cells of the proneural cluster (Fig. 1B,C). By contrast, proneural genes such as sc, l’sc (Cabrera et al., 1987; Romani et al., 1987) and ac (Fig. 1A) alread ...
Evolution of Gene Order and Chromosome Number in
Evolution of Gene Order and Chromosome Number in

... This information was placed in a phylogenetic context using an approximate tree of 18S ribosomal RNA sequences (Figure 3). The extent of linkage conservation falls off with increasing evolutionary distance from S. cerevisiae. At the extremes, gene order is completely conserved in the three other spe ...
Guppies – Quang Anh
Guppies – Quang Anh

... During this simulation, sexual selection also played an important part and it is most noticeable during the third simulation, when the predation level is low. During the third simulation, the gene frequency of the brightest guppies was the highest, at 0.78, and so, it proves that those are the ones ...
What is a biofilm?
What is a biofilm?

... •This paper has shown that mutant biofilms older than 72 hr where less sensitive to Tb than 24 hr old biofilms. This means that Tb treatment is more successful on younger biofilms • Not all strains are as sensitive to Tb as the one used in this ...
msb201035-sup
msb201035-sup

... development and have a CRM bound at either early (green) or late (red) stages of development. (a) The correlation between the timing of each TF separately to the timing of its target genes expression: the target genes for each TF were divided into early or late based on the timing of TF occupancy to ...
Bonus, a Drosophila TIF1 homologue, is a chromatin
Bonus, a Drosophila TIF1 homologue, is a chromatin

... pull-down with the T7 antibody. This is the case. Second, we performed a mock immunoprecipitation reaction using only blocked Protein A sepharose beads. This control determines the level of non-specific DNA interactions with the beads, and is essentially negligible in our experiments. Third, to rul ...
Uria_et_al_2006 _ADH paper
Uria_et_al_2006 _ADH paper

... chemical catalysis in many industrial applications (Van der Oost and De Graaff, 2001). In recent years, enzymes belonging to the oxidoreductase group such as alcohol dehydrogenases (ADHs) have caught much scientific attention in the pharmaceutical industries. They are highly desirable as biological ...
Polymorphism and expression of NF-B in relation to susceptibility and
Polymorphism and expression of NF-B in relation to susceptibility and

... allowed to continue, it will develop into cancer disease. To become cancerous, a cell must break several biological barriers. Two important barriers are apoptosis and cellular growth control. Cancer is a multifactorial disease caused by environmental and hereditary factors. The incidence of colorect ...
Duchenne and Becker Types of Muscular Dystrophy
Duchenne and Becker Types of Muscular Dystrophy

... gene may have a variation in the instruction that causes the gene to no longer function properly. This variation is called a mutation or pathogenic variant, and means that the product produced by the gene, called a protein, is impaired or even absent. Gene mutations may be inherited from a parent, o ...
and GvpD-mediated transcription regulation of the p
and GvpD-mediated transcription regulation of the p

... The transcription of the 14 p-gvp genes involved in gas vesicle formation of Halobacterium salinarum PHH1 is driven by the four promoters pA, pD, pF and pO. The regulation of these promoters was investigated in Haloferax volcanii transformants with respect to the endogenous regulatory proteins GvpE ...
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Epigenetics of diabetes Type 2

In recent years it has become apparent that the environment and underlying mechanisms affect gene expression and the genome outside of the central dogma of biology. It has been found that many Epigenetic mechanisms are involved in the regulation and expression of genes such as DNA methylation and chromatin remodeling. These epigenetic mechanisms are believed to be a contributing factor to pathological diseases such as Diabetes type II. An understanding of the epigenome of Diabetes patients may help to elucidate otherwise hidden causes of this disease.
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