cis-Regulatory Elements and trans-Acting Factors
... is particularly high in juxtaglomerularl and chorionic cells.8-'0 Juxtaglomerular cells are difficult to isolate and to culture, and they lose their ability to produce renin after a single passage.1',12 Attempts to immortalize these cells by the use of different SV40 mutants resulted in limited expr ...
... is particularly high in juxtaglomerularl and chorionic cells.8-'0 Juxtaglomerular cells are difficult to isolate and to culture, and they lose their ability to produce renin after a single passage.1',12 Attempts to immortalize these cells by the use of different SV40 mutants resulted in limited expr ...
Molecular genetics of Rett syndrome and clinical
... complex, which contains histone deacetylases 1 and 2 (HDAC1 and 2), the mechanism of repression was clari®ed [15]. HDACs cause chromatin to condense by removing acetyl groups from histones, and thereby make the DNA inaccessible to the transcriptional machinery. Recent evidence has demonstrated that ...
... complex, which contains histone deacetylases 1 and 2 (HDAC1 and 2), the mechanism of repression was clari®ed [15]. HDACs cause chromatin to condense by removing acetyl groups from histones, and thereby make the DNA inaccessible to the transcriptional machinery. Recent evidence has demonstrated that ...
Trachemys scripta elegans Red-Eared Turtle ( Fc)
... which the secretory tail is not encoded by a separate exon but rather by the sequence immediately downstream of the CH2 exon (21). Because Igs play important roles in the adaptive immune system of all jawed vertebrates (1, 2), they have been extensively studied in various groups of animals, includin ...
... which the secretory tail is not encoded by a separate exon but rather by the sequence immediately downstream of the CH2 exon (21). Because Igs play important roles in the adaptive immune system of all jawed vertebrates (1, 2), they have been extensively studied in various groups of animals, includin ...
PDF + SI - Development - The Company of Biologists
... Snail and Zeb transcription factors induce epithelial to mesenchymal transition (EMT) in embryonic and adult tissues by direct repression of E-Cadherin transcription. The repression of E-Cadherin transcription by the EMT inducers Snail1 and Zeb2 plays a fundamental role in defining embryonic territo ...
... Snail and Zeb transcription factors induce epithelial to mesenchymal transition (EMT) in embryonic and adult tissues by direct repression of E-Cadherin transcription. The repression of E-Cadherin transcription by the EMT inducers Snail1 and Zeb2 plays a fundamental role in defining embryonic territo ...
Detailed Algorithm of the DBRF
... divided into “independent groups” as follows. An essential unexplained edge is moved to a new independent group. An essential unexplained edge that explains or is explained by edges in the independent group is moved to the independent group. The process is repeated until no edge is moved to the inde ...
... divided into “independent groups” as follows. An essential unexplained edge is moved to a new independent group. An essential unexplained edge that explains or is explained by edges in the independent group is moved to the independent group. The process is repeated until no edge is moved to the inde ...
comparative evolution and development of the butterfly eyespot and
... The pattern element we know the most about is the butterfly eyespot, a common pattern element composed of concentric rings of different colors. Research has been focused on the eyespots of the tropical African butterfly Bicyclus anynana (discussed in Brakefield 1998). In this system, it has been sho ...
... The pattern element we know the most about is the butterfly eyespot, a common pattern element composed of concentric rings of different colors. Research has been focused on the eyespots of the tropical African butterfly Bicyclus anynana (discussed in Brakefield 1998). In this system, it has been sho ...
GROW`N`GLOW: THE ACE1 TWO-HYBRID
... MoBiTec's ACE1-based Grow'n'Glow yeast two-hybrid system is a version of a system originally developed by Fields and Song1. The yeast two-hybrid system has proven to be a powerful tool for identifying proteins from an expression library which can interact with one's protein of interest. The technolo ...
... MoBiTec's ACE1-based Grow'n'Glow yeast two-hybrid system is a version of a system originally developed by Fields and Song1. The yeast two-hybrid system has proven to be a powerful tool for identifying proteins from an expression library which can interact with one's protein of interest. The technolo ...
Selection of Suitable Endogenous Reference Genes for Relative
... transgene copy number by quantitative real-time PCR technique (qPCR) [12,16–18]. This method can trace the amplification of a target DNA sequence by monitoring fluorescence emitted from specific double-stranded DNA binding dyes or the fluorophore-labeled during the process of reaction [3,12,19]. In ...
... transgene copy number by quantitative real-time PCR technique (qPCR) [12,16–18]. This method can trace the amplification of a target DNA sequence by monitoring fluorescence emitted from specific double-stranded DNA binding dyes or the fluorophore-labeled during the process of reaction [3,12,19]. In ...
the art and design of genetic screens
... In TABLE 1 we give examples of the different types of system that are used for screening in E. coli. However, here we focus on one experimental system that can be used to study a wide range of biological processes. In so doing, our discussion encompasses logic and methods that are applicable to all ...
... In TABLE 1 we give examples of the different types of system that are used for screening in E. coli. However, here we focus on one experimental system that can be used to study a wide range of biological processes. In so doing, our discussion encompasses logic and methods that are applicable to all ...
Gene Section (Drosophila). Atlas of Genetics and Cytogenetics
... and telomeric (45g21, yellow) of NKX2-5. (See below for map.) The rearrangement may be a simple insertion or, a double translocation whereby chromosome 14 material is first translocated onto the der(5) and then returned by a nonreciprocal copying process to the der(14) accompanied by genomic materia ...
... and telomeric (45g21, yellow) of NKX2-5. (See below for map.) The rearrangement may be a simple insertion or, a double translocation whereby chromosome 14 material is first translocated onto the der(5) and then returned by a nonreciprocal copying process to the der(14) accompanied by genomic materia ...
Hox Genes: Let`s Work Together
... the activity of anteriorly expressed Hox gene even in the case of forced expression of anterior Hox gene using different promoter and only translated regions of the gene (Gonzalez-Reyes and Morata, 1990). This convincingly suggests that posterior Hox proteins also use post-translational mechanisms t ...
... the activity of anteriorly expressed Hox gene even in the case of forced expression of anterior Hox gene using different promoter and only translated regions of the gene (Gonzalez-Reyes and Morata, 1990). This convincingly suggests that posterior Hox proteins also use post-translational mechanisms t ...
Multiple Mechanisms Contribute to Lateral Transfer of an
... Escherichia coli and Acinetobacter strains, suggesting that the oriT identified in pPDL2 is functional. A welldefined replicative origin (oriV), repA was identified along with a plasmid addiction module relB/relE that would support stable maintenance of pPDL2 in Sphingobium fuliginis ATCC 27551. Howeve ...
... Escherichia coli and Acinetobacter strains, suggesting that the oriT identified in pPDL2 is functional. A welldefined replicative origin (oriV), repA was identified along with a plasmid addiction module relB/relE that would support stable maintenance of pPDL2 in Sphingobium fuliginis ATCC 27551. Howeve ...
Restriction Fragment Length Polymorphism of hsp70
... animals, but a distinct 4.4-kb fragment was present only in BN and WKY strains. A shorter fragment of 3 kb, although also evident in WKY rats, was seen in all SHR strains of Prague, Taconic, and Charles River origin. Noticeably, in WKY rats, both bands were visible but the intensity of hybridization ...
... animals, but a distinct 4.4-kb fragment was present only in BN and WKY strains. A shorter fragment of 3 kb, although also evident in WKY rats, was seen in all SHR strains of Prague, Taconic, and Charles River origin. Noticeably, in WKY rats, both bands were visible but the intensity of hybridization ...
Control of GL2 expression in Arabidopsis leaves and trichomes
... • Because both GL1 and R are required to ectopically activate GL2, it is possible that GL1 and R function as a complex • A construct containing the GL1 gene with a myc epitope as an Nterminal fusion was generated – This same epitope fusion was made to a truncated version of the GL1 protein that expr ...
... • Because both GL1 and R are required to ectopically activate GL2, it is possible that GL1 and R function as a complex • A construct containing the GL1 gene with a myc epitope as an Nterminal fusion was generated – This same epitope fusion was made to a truncated version of the GL1 protein that expr ...
PDF manual - QIAGEN Bioinformatics
... length fraction" and "Minimum similarity fraction" settings will be used only for the mapping of all entries in sequence lists where one or more of the reads is 56bp or longer. The mapping parameters are: • Maximum number of mismatches. This parameter is available if you have selected at least one s ...
... length fraction" and "Minimum similarity fraction" settings will be used only for the mapping of all entries in sequence lists where one or more of the reads is 56bp or longer. The mapping parameters are: • Maximum number of mismatches. This parameter is available if you have selected at least one s ...
Ensembl Introduction
... the UCSC and NCBI Browsers? • The gene set. Automatic annotation based on mRNA and protein information. ...
... the UCSC and NCBI Browsers? • The gene set. Automatic annotation based on mRNA and protein information. ...
Antisense Transcript and RNA Processing
... conduct a genetic screen to identify nuclear genes or chloroplast cis-elements that were involved in polyadenylation-stimulated degradation, and initial results suggested that suppressors that accumulated atpB mRNA could be readily obtained (Komine et al., 2002). Here, we report on an extensive anal ...
... conduct a genetic screen to identify nuclear genes or chloroplast cis-elements that were involved in polyadenylation-stimulated degradation, and initial results suggested that suppressors that accumulated atpB mRNA could be readily obtained (Komine et al., 2002). Here, we report on an extensive anal ...
The genetics of obesity - National Genetics Education Centre
... • One of the most commonly cited genes in relation to obesity is the FTO gene. • FTO regulates the hormone ghrelin, which is an appetite hormone responsible for eating behaviour. • Ghrelin stimulates hunger and increases food intake. Ghrelin reduces the sense of fullness after eating, causing furth ...
... • One of the most commonly cited genes in relation to obesity is the FTO gene. • FTO regulates the hormone ghrelin, which is an appetite hormone responsible for eating behaviour. • Ghrelin stimulates hunger and increases food intake. Ghrelin reduces the sense of fullness after eating, causing furth ...
MGF 360-17R Missing
... fragmentation of an ortholog into two smaller ORFs. For the bottom two genes of the 19R ortholog in the above diagram is shown to have a large in frame deletion in the gene when compared to the aligned genomes. ...
... fragmentation of an ortholog into two smaller ORFs. For the bottom two genes of the 19R ortholog in the above diagram is shown to have a large in frame deletion in the gene when compared to the aligned genomes. ...
Genome-wide identification and analysis of the SGR
... Structure analysis of the melon SGR genes CmSGR ORF lengths ranged from 504 (CmSGR4) to 774 bp (CmSGR2), molecular weights ranged from 19.02 (CmSGR4) to 29.48 kDa (CmSGR2), and pI values ranged from 6.19 (CmSGR4) to 8.72 (CmSGR2) (Table 1). CmSGR genes were distributed on all chromosome of the melon ...
... Structure analysis of the melon SGR genes CmSGR ORF lengths ranged from 504 (CmSGR4) to 774 bp (CmSGR2), molecular weights ranged from 19.02 (CmSGR4) to 29.48 kDa (CmSGR2), and pI values ranged from 6.19 (CmSGR4) to 8.72 (CmSGR2) (Table 1). CmSGR genes were distributed on all chromosome of the melon ...
Sequence of the Tribolium castaneum Homeotic Complex
... Sequence analysis: The previously identified cDNAs were mapped on the BAC sequences by comparing cDNA and genomic sequence. The following GenBank accession numbers correspond to the cDNA sequences used: Tclab, AF231104 and AF230312; mxp, AF187068 and AF187069; Tczen1, X97819; Tczen2, AF452568; TcDfd ...
... Sequence analysis: The previously identified cDNAs were mapped on the BAC sequences by comparing cDNA and genomic sequence. The following GenBank accession numbers correspond to the cDNA sequences used: Tclab, AF231104 and AF230312; mxp, AF187068 and AF187069; Tczen1, X97819; Tczen2, AF452568; TcDfd ...
Evolution of Closely Linked Gene Pairs in
... functional entity, a monocistronic coding sequence of which the expression is controlled by an autonomous promoter. In fact, there is a significant clustering of genes in the mammalian genome where the genes in these clusters show coordinate expression (Hurst et al. 2004; The FANTOM Consortium 2005; ...
... functional entity, a monocistronic coding sequence of which the expression is controlled by an autonomous promoter. In fact, there is a significant clustering of genes in the mammalian genome where the genes in these clusters show coordinate expression (Hurst et al. 2004; The FANTOM Consortium 2005; ...
Why we have (only) five fingers per hand: Hox genes
... the anterior-posterior axis. However, the Hox-4 genes are also coordinately expressed in the CNS and elsewhere in the body mesenchyme. Thus to alter their expression would affect more than just the limb. In theory, the effects of a newly derived Hox-4 gene could be limited to the limbs by creating a ...
... the anterior-posterior axis. However, the Hox-4 genes are also coordinately expressed in the CNS and elsewhere in the body mesenchyme. Thus to alter their expression would affect more than just the limb. In theory, the effects of a newly derived Hox-4 gene could be limited to the limbs by creating a ...
Resistance to cephalosporins and carbapenems in Gram
... original definition due to extension of the spectrum of already widely disseminated plasmid-encoded -lactamases by amino acid substitution; (b) acquisition of genes encoding ESBL from environmental bacteria as, for instance the CTX-M-type -lactamases from Kluyvera spp.; (c) high-level expression of ...
... original definition due to extension of the spectrum of already widely disseminated plasmid-encoded -lactamases by amino acid substitution; (b) acquisition of genes encoding ESBL from environmental bacteria as, for instance the CTX-M-type -lactamases from Kluyvera spp.; (c) high-level expression of ...
Hthsci 2231
... 4. An individual that inherits a normal gene from one parent and a cystic fibrosis gene from the other parent is called a ___________. 5. The term “carrier” can be defined as: 6. How does an individual acquire the disease, cystic fibrosis? 7. If both parents carry a recessive gene for cystic fibrosi ...
... 4. An individual that inherits a normal gene from one parent and a cystic fibrosis gene from the other parent is called a ___________. 5. The term “carrier” can be defined as: 6. How does an individual acquire the disease, cystic fibrosis? 7. If both parents carry a recessive gene for cystic fibrosi ...