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WOX4 - Durham Research Online
WOX4 - Durham Research Online

... radial axis of the stem. These divisions result in highly distinctive cell files that are characteristic of the xylem in most dicots. The cell files that are generated are also essential for maintaining the spatial separation of xylem and phloem (Caño-Delgado et al., 2010). These properties make vas ...
שקופית 1
שקופית 1

... • Together with the a subunit, the eLH/CGb gene is expressed in the pituitary to synthesize eLH and in the placenta to produce eCG (also known as PMSG) as part of reproduction endocrinology in mares • The pituitary eLHb and placental eCGb subunits share the same amino acid composition and both have ...
IGA 8/e Chapter 4
IGA 8/e Chapter 4

... 10. Eight phenotypic classes are expected for three autosomal genes, whether or not they are linked, when all three genes have simple dominant-recessive relationships among their alleles. The general formula for the number of expected phenotypes is 2n , where n is the number of genes being studied. ...
Disruption of mCry2 restores circadian rhythmicity in mPer2 mutant
Disruption of mCry2 restores circadian rhythmicity in mPer2 mutant

... 2a). Thus, circadian expression of mPer1 in Per2Brdm1 mutants is rescued by inactivation of mCry2. A similar rescue was observed for mCry1 expression: both amplitude and timing of mCry1 oscillation in Per2Brdm1/ mCry2−/− mutant animals was not significantly different from that observed in wild-type ...
VECTOR SYSTEMS XXVII.indd
VECTOR SYSTEMS XXVII.indd

... Our Bacillus megaterium kit is a new easy-to-handle system for stable protein expression with high yield. It is not only suited for industrial large scale protein production, but offers also an interesting alternative to the standard host E. coli. The kit comes with the E. coli/Bacillus megaterium s ...
Towards an accurate identification of mosaic genes and
Towards an accurate identification of mosaic genes and

... imposed by the necessity for taxa involved in HGT to be contemporaneous (6,18,20). Fix the sliding window size w and the step size s. In our experiments, the window sizes of l/5, l/4, l/3 and l/2 sites and the sliding window progress step of 10 sites were used. Step k. Fix the position of the slidin ...
Scientist finds the gene that determines major sensitivity to bitter taste
Scientist finds the gene that determines major sensitivity to bitter taste

... strong linkage disequilibrium between SNP markers (single nucleotide polymorphisms), and PTC sensitivity in unrelated subjects gathered at the NIH. SNPs are the DNA sequence variations that occur when a single nucleotide (A,T,C,or G) in the genome sequence is altered. The region on 7 q contains a si ...


... into close proximity [11-13]. 3C technology detects interactions between DNA regions by in vivo crosslinking of chromatin and PCR with primers specific for novel junctions created by ligation of sequences that were in close proximity through specific interactions. To determine if the Kcnq1 promoter ...
The Genetics of Spinal Muscular Atrophy
The Genetics of Spinal Muscular Atrophy

... Figure 5. Schematic of a portion of chromosome 5 that contains the two SMN genes. The major difference between the two SMN gene copies is the C (SMN1) to T (SMN2) nucleotide change in exon 7 in their DNA. Because of this difference, SMN2 mostly makes mRNA message that excludes exon 7 and produces a ...
Evolution 2010 Wilkins
Evolution 2010 Wilkins

... fitness are likely to be quite similar in most cases. However, if we consider a pair of antagonistic loci (e.g., a paternally expressed growth enhancer and a maternally expressed growth suppressor), the simplest model permits no pattern of expression that is evolutionarily stable simultaneously at b ...
Ectopic induction and reorganization of Wnt-1
Ectopic induction and reorganization of Wnt-1

... later-occurring regulatory interactions in met-mesencephalon could not be studied since the whole En-expressing domain rapidly disappears. In particular, what role Wnt-1 plays after its expression domain has been restricted to a narrow ring is not known. We and others have been studying the organiza ...
The Development of a Genetic Marker for Resistance to Fescue
The Development of a Genetic Marker for Resistance to Fescue

... rough, thick hair coat in the summer, decreased feed intake, and decreased serum prolactin levels, which drastically affect reproductive ability (Roberts and Andrae, 2004). Studies have indicated that binding of ergopeptides, the active compounds produced by endophyte, to dopamine 2 receptors (DRD2) ...
Towards an accurate identification of mosaic genes and partial
Towards an accurate identification of mosaic genes and partial

... assess the level of mosaicism in the considered genomes as well as the rates of complete and partial HGT underlying their evolution. INTRODUCTION Horizontal gene transfer (HGT) (also called lateral gene transfer) is one of the major mechanisms contributing to microbial genome diversification. HGT is ...
The Mutant of sll1961, Which Encodes a Putative
The Mutant of sll1961, Which Encodes a Putative

... 2003; Wang et al., 2004). The deletion of genes encoding the subunits of PSI or PSII may lead to the decrease of relative PSI or PSII content. The disruption of genes involved in transcription, translation, assembly, or biogenesis of PSI or PSII may lead to the change in photosystem stoichiometry. O ...
XASH genes promote neurogenesis in Xenopus embryos
XASH genes promote neurogenesis in Xenopus embryos

... by XASH-3 is unstable Activation of neural gene expression by XASH-3 suggests that XASH-3 promotes neural differentiation. Similar studies using injection of XmyoD RNA, however, have shown that XMyoD can activate muscle gene expression in animal cap assays without causing the differentiation of ecto ...
5 The Genetics of Bacteria and Their Viruses
5 The Genetics of Bacteria and Their Viruses

... a. Hfr crosses by conjugation and generalized transduction. b. F′ derivatives such as F′ lac and specialized transduction. Answer: a. Hfr cells involved in conjugation transfer host genes in a linear fashion. The genes transferred depend on both the Hfr strain and the length of time during which the ...
BLSSpeller: exhaustive comparative discovery of
BLSSpeller: exhaustive comparative discovery of

... (osa), Brachypodium distachyon (bdi), Sorghum bicolor (sbi) and Zea mays (zma). We adopt a gene-centric approach, where the promoter sequences of orthologous genes are grouped into gene families. A word-based discovery algorithm was designed to exhaustively report all genome-wide conserved motifs. T ...
WOX4 and WOX14 act downstream of the PXY
WOX4 and WOX14 act downstream of the PXY

... by a small (1.3-fold) but significant amount, and this reduction was more apparent in the middle of the stem (Fig. 4B). The trend of reduced WOX14 expression appeared similar in the stem base of pxy mutants, but these differences proved not to be statistically significant. In 35S::CLE41 lines, WOX4 ...
WOX4 and WOX14 act downstream of the PXY
WOX4 and WOX14 act downstream of the PXY

... within these tissues are thin and extremely long. They are particularly unusual as they divide down their long axis in a highly ordered manner, parallel to the tangential axis of the stem. CLAVATA3-LIKE/ESR-RELATED 41 (CLE41) and PHLOEM INTERCALATED WITH XYLEM (PXY) are a multifunctional ligand-rece ...
GENES AND DEVELOPMENTAL PATHWAYS
GENES AND DEVELOPMENTAL PATHWAYS

... of the chromosome or genome which contains the information needed to specify the sequence of amino acids in a single protein or polypeptide. It is useful to define the gene in this way since it allows one to retain the widely applicable principle of "one-gene one-enzyme" or "one-gene onepolypeptide. ...
Mapping of the Recessive White Locus and
Mapping of the Recessive White Locus and

... phaeomelanin. In the synthesis pathways of both of these melanins, tyrosinase-induced oxidation of Tyr, which is the first biochemical step, leads to production of dihydroxyphenylalanine and then, via oxidation of dihydroxyphenylalanine, the production of dopaquinone (Lerner and Fitzpatrick, 1950). ...
SERIES ‘‘THE GENETIC AND CARDIOVASCULAR ASPECTS OF OBSTRUCTIVE SLEEP APNOEA/HYPOPNOEA SYNDROME’’
SERIES ‘‘THE GENETIC AND CARDIOVASCULAR ASPECTS OF OBSTRUCTIVE SLEEP APNOEA/HYPOPNOEA SYNDROME’’

... single mutations directly linked to obesity have been found in rare cases; there are no other genetic associations resulting from a mutation affecting function or amount of gene product. The support of cellular work is also lacking at the present time. Sleepiness Sleepiness, as a consequence of SDB, ...
High-Level Expression in Escherichia coli of Alkaline Phosphatase
High-Level Expression in Escherichia coli of Alkaline Phosphatase

... Tca APase activity was activated by Mg2+; however, it was inhibited by Ca2+, Co2+, Zn2+, and EDTA at 1 mM concentration (data not shown). This dependence of the catalytic activity on Mg2+ has already been observed in most of the APases investigated [2, 5, 10]. The above results thus indicate that pr ...
Obligate phototrophy in cyanobacteria: more than a lack of sugar
Obligate phototrophy in cyanobacteria: more than a lack of sugar

... distinct characteristics. In P. boryanum uptake is inducible by glucose, and the glucose analogue Kmethyl-glucoside shows high competitive e¡ect rather than OMG in Synechocystis [6^8]. The transport system has no a¤nity for fructose, which is transported via a distinct system and also used as a subs ...
The importance of alternative splicing in the drug discovery process
The importance of alternative splicing in the drug discovery process

... study the function of the gene. However, it turned out that abnormal, disease-causing splicing. Such an approach was not all the gene is shut down and a residual binding activused to correct an aberrant splicing of the cystic fibrosis ity remains in uterine tissue. A recent study showed that transme ...
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Epigenetics of diabetes Type 2

In recent years it has become apparent that the environment and underlying mechanisms affect gene expression and the genome outside of the central dogma of biology. It has been found that many Epigenetic mechanisms are involved in the regulation and expression of genes such as DNA methylation and chromatin remodeling. These epigenetic mechanisms are believed to be a contributing factor to pathological diseases such as Diabetes type II. An understanding of the epigenome of Diabetes patients may help to elucidate otherwise hidden causes of this disease.
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