AUTISM AS A PARADIGMATIC COMPLEX GENETIC DISORDER
... colorectal cancer (HNPCC) (96). This idea becomes more complicated in complex genetic disorders, where different (likely overlapping) groups of genetic variants may cause susceptibility to disease. The large range of symptoms across individuals with ASD suggests that locus heterogeneity will probabl ...
... colorectal cancer (HNPCC) (96). This idea becomes more complicated in complex genetic disorders, where different (likely overlapping) groups of genetic variants may cause susceptibility to disease. The large range of symptoms across individuals with ASD suggests that locus heterogeneity will probabl ...
Insights into three whole-genome duplications gleaned
... estimated gaps) is composed of 1,202 scaffolds, 274 of which have lengths >2 kb and 96 of which are >50 kb (Table S1). This is less than half the genome size of all members of the P. aurelia complex that have been sequenced (68-77 Mb) (McGrath et al., submitted), and consistent with P. caudatum havi ...
... estimated gaps) is composed of 1,202 scaffolds, 274 of which have lengths >2 kb and 96 of which are >50 kb (Table S1). This is less than half the genome size of all members of the P. aurelia complex that have been sequenced (68-77 Mb) (McGrath et al., submitted), and consistent with P. caudatum havi ...
High-Level Expression in Escherichia coli of Alkaline Phosphatase
... Tca APase activity was activated by Mg2+; however, it was inhibited by Ca2+, Co2+, Zn2+, and EDTA at 1 mM concentration (data not shown). This dependence of the catalytic activity on Mg2+ has already been observed in most of the APases investigated [2, 5, 10]. The above results thus indicate that pr ...
... Tca APase activity was activated by Mg2+; however, it was inhibited by Ca2+, Co2+, Zn2+, and EDTA at 1 mM concentration (data not shown). This dependence of the catalytic activity on Mg2+ has already been observed in most of the APases investigated [2, 5, 10]. The above results thus indicate that pr ...
Obligate phototrophy in cyanobacteria: more than a lack of sugar
... distinct characteristics. In P. boryanum uptake is inducible by glucose, and the glucose analogue Kmethyl-glucoside shows high competitive e¡ect rather than OMG in Synechocystis [6^8]. The transport system has no a¤nity for fructose, which is transported via a distinct system and also used as a subs ...
... distinct characteristics. In P. boryanum uptake is inducible by glucose, and the glucose analogue Kmethyl-glucoside shows high competitive e¡ect rather than OMG in Synechocystis [6^8]. The transport system has no a¤nity for fructose, which is transported via a distinct system and also used as a subs ...
TEV_v7_BY
... present in the C57BL/6J reference mouse genome are drawn from three distinct classes, namely short interspersed nuclear elements (SINEs), long interspersed nuclear elements (LINEs) and members of the endogenous retrovirus (ERV) superfamily. Despite their high prevalence, the relative contribution of ...
... present in the C57BL/6J reference mouse genome are drawn from three distinct classes, namely short interspersed nuclear elements (SINEs), long interspersed nuclear elements (LINEs) and members of the endogenous retrovirus (ERV) superfamily. Despite their high prevalence, the relative contribution of ...
Characterization and regulation of the bovine stearoyl-CoA desaturase gene promoter
... of CLA to dairy cows can have effects on the desaturase ratio. For this reason we were interested in the effect that CLA would have on activation of the bovine Scd gene promoter. Mac-T cells were transfected with a number of luciferase reporter vectors under the control of varying lengths of the Scd g ...
... of CLA to dairy cows can have effects on the desaturase ratio. For this reason we were interested in the effect that CLA would have on activation of the bovine Scd gene promoter. Mac-T cells were transfected with a number of luciferase reporter vectors under the control of varying lengths of the Scd g ...
Regulation of Bacterial Conjugation in Microaerobiosis by
... et al. 2005b). Another example involves the leucineresponsive regulatory protein, which is an activator of traJ transcription in pSLT (Camacho and Casadesus 2002) but not in R100 (Starcic-Erjavec et al. 2003). Adaptation to the host lifestyle and adjustment of conjugal transfer to favorable circumst ...
... et al. 2005b). Another example involves the leucineresponsive regulatory protein, which is an activator of traJ transcription in pSLT (Camacho and Casadesus 2002) but not in R100 (Starcic-Erjavec et al. 2003). Adaptation to the host lifestyle and adjustment of conjugal transfer to favorable circumst ...
Microarray data normalization and transformation
... median intensities are the same within a single array or across all arrays, or using a selected subset of the arrayed genes rather than the entire collection. Lowess normalization In addition to total intensity normalization described above, there are a number of alternative approaches to normalizin ...
... median intensities are the same within a single array or across all arrays, or using a selected subset of the arrayed genes rather than the entire collection. Lowess normalization In addition to total intensity normalization described above, there are a number of alternative approaches to normalizin ...
Document
... In the context of the human genome project … How do we make all that interesting natural-language information out there easily accessible? ...
... In the context of the human genome project … How do we make all that interesting natural-language information out there easily accessible? ...
Using GO to improve text information access
... In the context of the human genome project … How do we make all that interesting natural-language information out there easily accessible? ...
... In the context of the human genome project … How do we make all that interesting natural-language information out there easily accessible? ...
Slide 1
... depends on the # of tests that you do, so, no matter what, the more tests you do, the more sensitive the test needs to be • Can control the stringency by reducing the number of tests: e.g. use GO slim; restrict testing to the appropriate GO annotations; or select only larger GO categories. Module 2 ...
... depends on the # of tests that you do, so, no matter what, the more tests you do, the more sensitive the test needs to be • Can control the stringency by reducing the number of tests: e.g. use GO slim; restrict testing to the appropriate GO annotations; or select only larger GO categories. Module 2 ...
O4 M.A. Rouf Mian
... northern soybean growing region of the USA in 2000. By 2004, 80% of the U.S. soybean field was infested by SA. The SA is native to southeastern and eastern Asia and it is long been a pest of soybean in many Asian countries. Three plant introductions (PIs) (PI 243540, PI 567301B, and PI 567324) were ...
... northern soybean growing region of the USA in 2000. By 2004, 80% of the U.S. soybean field was infested by SA. The SA is native to southeastern and eastern Asia and it is long been a pest of soybean in many Asian countries. Three plant introductions (PIs) (PI 243540, PI 567301B, and PI 567324) were ...
Prothrombin Gene Mutation - Hamilton Health Sciences
... No treatment can prevent the prothrombin gene mutation or make it go away. The goal of treatment is to prevent blood clots (see next question and page 7). If you have had a blood clot, you may be treated with medications called anticoagulants. Anticoagulants are used to help to prevent blood clots. ...
... No treatment can prevent the prothrombin gene mutation or make it go away. The goal of treatment is to prevent blood clots (see next question and page 7). If you have had a blood clot, you may be treated with medications called anticoagulants. Anticoagulants are used to help to prevent blood clots. ...
Mol Biol Evol-2015-Lipinska-15
... dimorphism. In Ectocarpus, female-biased genes were found to be evolving as rapidly as male-biased genes. Moreover, genes expressed at fertility showed faster rates of evolution than genes expressed in immature gametophytes. Both maleand female-biased genes had a greater proportion of sites experien ...
... dimorphism. In Ectocarpus, female-biased genes were found to be evolving as rapidly as male-biased genes. Moreover, genes expressed at fertility showed faster rates of evolution than genes expressed in immature gametophytes. Both maleand female-biased genes had a greater proportion of sites experien ...
XSL Formatter - H:\XML
... used in different maps are synchronized, we can see the FMR1 gene if we ask for the Genes_seq track in the region corresponding to the hit on the STS map. To do this, we can select the Maps & Options link [(a)], highlight the Gene map from the list of available maps in the left-hand box, and select ...
... used in different maps are synchronized, we can see the FMR1 gene if we ask for the Genes_seq track in the region corresponding to the hit on the STS map. To do this, we can select the Maps & Options link [(a)], highlight the Gene map from the list of available maps in the left-hand box, and select ...
IMPLICATIONS OF GENETIC TESTING ON HEMOCHROMATOSIS
... How do we predict cirrhosis? You might think this is in the realm of the hepatologists, and it is ; but as an insurance person, the number one factor that is going to predict an individual’s risk is whether or not he or she has cirrhosis. Do we always need to do a biopsy? The answer is no. This is a ...
... How do we predict cirrhosis? You might think this is in the realm of the hepatologists, and it is ; but as an insurance person, the number one factor that is going to predict an individual’s risk is whether or not he or she has cirrhosis. Do we always need to do a biopsy? The answer is no. This is a ...
comparing quantitative trait loci and gene expression data
... also miss some interesting genes (Wayne and Mclntyre, 2002). Second, the high level of experimental error and limitations of analysis in microarray data introduce mistakes in the identification of relevant genes. Finally, QTL studies include the entire genome including noncoding regions, while micro ...
... also miss some interesting genes (Wayne and Mclntyre, 2002). Second, the high level of experimental error and limitations of analysis in microarray data introduce mistakes in the identification of relevant genes. Finally, QTL studies include the entire genome including noncoding regions, while micro ...
Synthetic Biology and the CBD
... arrangements and that “there is insufficient evidence available at this time to support the release of gene2 drive modified organisms.” NAS also identified the CBD as the main international regulatory instrument for addressing this topic. “Because gene-drive modified organisms are intended to spread ...
... arrangements and that “there is insufficient evidence available at this time to support the release of gene2 drive modified organisms.” NAS also identified the CBD as the main international regulatory instrument for addressing this topic. “Because gene-drive modified organisms are intended to spread ...
Chapter 12 Recombinant DNA Technology Key Concepts
... its DNA sequence examined directly. Indeed, it seemed impossible to isolate an individual gene from the genome. Although it is relatively easy to isolate DNA from living tissue, DNA in a test tube looks like a glob of mucus. How could it be possible to isolate a single gene from this tangled mass o ...
... its DNA sequence examined directly. Indeed, it seemed impossible to isolate an individual gene from the genome. Although it is relatively easy to isolate DNA from living tissue, DNA in a test tube looks like a glob of mucus. How could it be possible to isolate a single gene from this tangled mass o ...
Becker Muscular Dystrophy (BMD)
... The symptoms of BMD vary greatly from one person to another. Some people lose their ability to walk in early adulthood. Others are able to continue walking throughout their lives. Life expectancy can be reduced, but many people with BMD live into their 70s and 80s. Some may develop heart problems ea ...
... The symptoms of BMD vary greatly from one person to another. Some people lose their ability to walk in early adulthood. Others are able to continue walking throughout their lives. Life expectancy can be reduced, but many people with BMD live into their 70s and 80s. Some may develop heart problems ea ...
Regulation of the S100B gene by α1-adrenergic - AJP
... of this adaptive response. Because adult cardiac myocytes are terminally differentiated and have lost the ability to divide, this increase in mass is due to enlargement of individual myocytes. The hypertrophic response can be reproduced in rat and mouse experimental models and cultured neonatal card ...
... of this adaptive response. Because adult cardiac myocytes are terminally differentiated and have lost the ability to divide, this increase in mass is due to enlargement of individual myocytes. The hypertrophic response can be reproduced in rat and mouse experimental models and cultured neonatal card ...
Genetic Insights Into Comparative Morphology
... al., 1995; Suemori et al., 1995). Consistent results have also been obtained by the retinoic acid-induced respecification of vertebrae, which is roughly associated with the shift of the Hox code in the provertebrae (Kessel and Gruss, 1991; Kessel, 1992). It has been shown recently that multiple disr ...
... al., 1995; Suemori et al., 1995). Consistent results have also been obtained by the retinoic acid-induced respecification of vertebrae, which is roughly associated with the shift of the Hox code in the provertebrae (Kessel and Gruss, 1991; Kessel, 1992). It has been shown recently that multiple disr ...
Chapter 1.
... near-isogenic lines. The NILs are similar for all traits except the major resistance genes. DNA polymorphisms between different NILs are likely to be associated with the different resistance genes. Screening molecular markers by use of NILs is simple and easy. But the NILs for most disease resistanc ...
... near-isogenic lines. The NILs are similar for all traits except the major resistance genes. DNA polymorphisms between different NILs are likely to be associated with the different resistance genes. Screening molecular markers by use of NILs is simple and easy. But the NILs for most disease resistanc ...
For Official Use ENV/JM/BIO(2006)6/REV3 Working
... belonging to the same species, and transformation frequencies can vary up to four orders of magnitude among transformable isolates of a species (Sikorski et al., 2002; Maamar and Dubnau, 2005). The uptake of DNA can serve as a nutrient source, for DNA repair or as a source of genetic innovation (Dub ...
... belonging to the same species, and transformation frequencies can vary up to four orders of magnitude among transformable isolates of a species (Sikorski et al., 2002; Maamar and Dubnau, 2005). The uptake of DNA can serve as a nutrient source, for DNA repair or as a source of genetic innovation (Dub ...
Cloning and Expression of Cellulosimicrobium cellulans β
... at 94°C for 2 min, then 30 cycles of denaturation at 98°C for 10 s, annealing and elongation at 68°C for 5 min. A final extension step was performed as 72°C for 5 min. PCR reaction performed with recombinant plasmid analysed by agarose gel (0.8% wt/v) electrophoresis. For restriction endonuclease an ...
... at 94°C for 2 min, then 30 cycles of denaturation at 98°C for 10 s, annealing and elongation at 68°C for 5 min. A final extension step was performed as 72°C for 5 min. PCR reaction performed with recombinant plasmid analysed by agarose gel (0.8% wt/v) electrophoresis. For restriction endonuclease an ...