Estimating lethal allele frequencies in complex pedigrees via gene
... Gene dropping approach (GD) We propose a modified version of the GD developed by MACCLUER et al. (1986). This method is based on the idea of gene flow through a pedigree introduced by EDWARDS (1968). Two unique alleles are assigned to each founder (founder is defined as an ancestor with unknown pare ...
... Gene dropping approach (GD) We propose a modified version of the GD developed by MACCLUER et al. (1986). This method is based on the idea of gene flow through a pedigree introduced by EDWARDS (1968). Two unique alleles are assigned to each founder (founder is defined as an ancestor with unknown pare ...
lac
... -DNA sequence that functions exclusively as a DNA sequence -affects only DNA to which it is physically linked -eg. promoter/operator ...
... -DNA sequence that functions exclusively as a DNA sequence -affects only DNA to which it is physically linked -eg. promoter/operator ...
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... mine all types of data from NCBI. Once you have found the gene that you are interested from either from an ENTREZ search or an OMIM search, you should now be able to navigate to: 1) find the RefSeq for the gene and all important variants; 2) nucleotide sequence; 3) protein sequence; 4) gene location ...
... mine all types of data from NCBI. Once you have found the gene that you are interested from either from an ENTREZ search or an OMIM search, you should now be able to navigate to: 1) find the RefSeq for the gene and all important variants; 2) nucleotide sequence; 3) protein sequence; 4) gene location ...
localization of histone gene transcripts in newt lampbrush
... sequences during oogenesis in Amphibia and certain other animals. The other favourable situation is provided by polytene chromosomes of larval Diptera, where many identical DNA sequences lie in lateral register with one another. There is yet another favourable situation which has hitherto been littl ...
... sequences during oogenesis in Amphibia and certain other animals. The other favourable situation is provided by polytene chromosomes of larval Diptera, where many identical DNA sequences lie in lateral register with one another. There is yet another favourable situation which has hitherto been littl ...
Gene Section LMO2 (LIM domain only 2 (rhombotin-like 1))
... Hematopoiesis: LMO2 directly interacts with the basicloop-helix protein TAL1/SCL and the GATA DNA protein GATA1. They form a transcriptional complex: LMO2 has no direct evidence in DNA binding capacity but could act as a bridging molecule bringing together different DNA binding factors (TAL1, LDB1, ...
... Hematopoiesis: LMO2 directly interacts with the basicloop-helix protein TAL1/SCL and the GATA DNA protein GATA1. They form a transcriptional complex: LMO2 has no direct evidence in DNA binding capacity but could act as a bridging molecule bringing together different DNA binding factors (TAL1, LDB1, ...
PDF
... 2010) identified the novel computational PRC2-homologs in several unicellular species and showed that E(z)-homolog in unicellular green algae Chlamydomonas reinhardtii is responsible for mono- and di-methylation of lysine 27 on histone H3. As the tri-methylation activity of Chlamydomonas E(z) homolo ...
... 2010) identified the novel computational PRC2-homologs in several unicellular species and showed that E(z)-homolog in unicellular green algae Chlamydomonas reinhardtii is responsible for mono- and di-methylation of lysine 27 on histone H3. As the tri-methylation activity of Chlamydomonas E(z) homolo ...
Factor V Leiden Information for Patients and Families
... There are 2 copies for Factor V gene, which are passed down from our parents. We inherit one gene from our mother and one from our father. At least 1 of the genes that you inherited is the mutated gene that makes the Factor V Leiden protein. ...
... There are 2 copies for Factor V gene, which are passed down from our parents. We inherit one gene from our mother and one from our father. At least 1 of the genes that you inherited is the mutated gene that makes the Factor V Leiden protein. ...
The Mycobacterium tuberculosis katG promoter region contains a
... is in the correct orientation to promote expression of the luciferase gene. The 262 bp HindIII–SphI fragment of pK20 containing the katG upstream activator region (UAR) was cloned upstream of the PAN promoter in pLPan to form pLPuar. The structures of all the above constructs were confirmed by DNA s ...
... is in the correct orientation to promote expression of the luciferase gene. The 262 bp HindIII–SphI fragment of pK20 containing the katG upstream activator region (UAR) was cloned upstream of the PAN promoter in pLPan to form pLPuar. The structures of all the above constructs were confirmed by DNA s ...
Pierre MADL Div. of Material Sciences Dep
... that an organism can pass on characteristics that it acquired during its lifetime to its offspring (also known as based on heritability of acquired characteristics or "soft inheritance"). It is named for the French biologist Jean-Baptiste Lamarck, who incorporated the action of soft inheritance into ...
... that an organism can pass on characteristics that it acquired during its lifetime to its offspring (also known as based on heritability of acquired characteristics or "soft inheritance"). It is named for the French biologist Jean-Baptiste Lamarck, who incorporated the action of soft inheritance into ...
Drug-specific Sites of Topoisomerase II DNA
... The addition of distamycin (25 @i)to Kc cells has been shown to stimulation by dh-EPI at the 5' end of the Hi gene and only weak stimulation between the H3 and H4 genes (sites 8a and 8b in Fig. 3). markedly increase VM-26-stimulated cleavage levels in SAR regions Weaker sites stimulated by dh-EPI we ...
... The addition of distamycin (25 @i)to Kc cells has been shown to stimulation by dh-EPI at the 5' end of the Hi gene and only weak stimulation between the H3 and H4 genes (sites 8a and 8b in Fig. 3). markedly increase VM-26-stimulated cleavage levels in SAR regions Weaker sites stimulated by dh-EPI we ...
Neurofibromatosis, Type 1 - St. Jude Children`s Research Hospital
... Neurofibromatosis, type 1, is hereditary, which means it can be passed from parents to children in a family. However, the severity of the condition and which body areas are affected can vary from person to person. How is neurofibromatosis, type 1, diagnosed? A diagnosis of neurofibromatosis, type 1, ...
... Neurofibromatosis, type 1, is hereditary, which means it can be passed from parents to children in a family. However, the severity of the condition and which body areas are affected can vary from person to person. How is neurofibromatosis, type 1, diagnosed? A diagnosis of neurofibromatosis, type 1, ...
Lack of expression of XIST from a small ring X chromosome
... HhaI resulted in loss of only one allele, that from the active X chromosome (Figure 3B). The ZXDA gene in Xp11 contains a polymorphic CA repeat in the transcribed but untranslated region of the gene. This gene is subject to X-chromosome inactivation, so expression of only the allele on the active X ...
... HhaI resulted in loss of only one allele, that from the active X chromosome (Figure 3B). The ZXDA gene in Xp11 contains a polymorphic CA repeat in the transcribed but untranslated region of the gene. This gene is subject to X-chromosome inactivation, so expression of only the allele on the active X ...
The Role of the Susceptibility Gene in the Pathogenesis of Age
... Age-related macular degeneration (AMD) is the leading cause of central vision loss in the people over 60s in the world. There are two main types of age-related macular degeneration: dry form (atrophic) and the wet form (choroidal neovascularization, CNV) [1]. The most common type of AMD is the dry f ...
... Age-related macular degeneration (AMD) is the leading cause of central vision loss in the people over 60s in the world. There are two main types of age-related macular degeneration: dry form (atrophic) and the wet form (choroidal neovascularization, CNV) [1]. The most common type of AMD is the dry f ...
Martina Šeruga Musić, Mladen Krajačić, Dijana Škorić
... presence of potential mutations is detected as a band shift or as a change in number of bands. Thus, conditions for the SSCP analysis have to be established empirically for each set of fragments. However, there are mutations still undetectable by the SSCP analysis. One of the most utilized protocols ...
... presence of potential mutations is detected as a band shift or as a change in number of bands. Thus, conditions for the SSCP analysis have to be established empirically for each set of fragments. However, there are mutations still undetectable by the SSCP analysis. One of the most utilized protocols ...
Analysis of alternative splicing in Drosophila genetic
... of clones of cells with altered regulator levels in a field of normal cells. Using such genetic mosaics even subtle changes in the activity of a splicing reporter can be visualized by direct comparison of cells growing side by side within the same tissue of the same individual. In addition, because ...
... of clones of cells with altered regulator levels in a field of normal cells. Using such genetic mosaics even subtle changes in the activity of a splicing reporter can be visualized by direct comparison of cells growing side by side within the same tissue of the same individual. In addition, because ...
Replication of plasmids with the p15A origin in Shewanella
... Both pACYC184 and pCMDN1 were stably maintained in MR-1 through repeated passage into fresh medium containing Tc. We observed transformation efficiencies of 70– 3600 Tcr transformants per mg of pACYC184 or pCMDN1 DNA. While these efficiencies are low, our previous experience with electroporation of ...
... Both pACYC184 and pCMDN1 were stably maintained in MR-1 through repeated passage into fresh medium containing Tc. We observed transformation efficiencies of 70– 3600 Tcr transformants per mg of pACYC184 or pCMDN1 DNA. While these efficiencies are low, our previous experience with electroporation of ...
Diversity of DNA methyltransferases that recognize asymmetric
... Multiple lines of evidence suggest that some DNA MTases function as dimers. Further, functional analysis of many restriction-modification systems showed the presence of more than one or fused MTase genes. It was proposed that presence of two MTases responsible for the recognition and methylation of ...
... Multiple lines of evidence suggest that some DNA MTases function as dimers. Further, functional analysis of many restriction-modification systems showed the presence of more than one or fused MTase genes. It was proposed that presence of two MTases responsible for the recognition and methylation of ...
Document
... the product information currently provided by the manufacturer to verify appropriate dosage, method and duration of administration, and other relevant information. In all instances, it is the responsibility of the treating physician or other healthcare professional, relying on independent experience ...
... the product information currently provided by the manufacturer to verify appropriate dosage, method and duration of administration, and other relevant information. In all instances, it is the responsibility of the treating physician or other healthcare professional, relying on independent experience ...
ABO Blood Group System
... The ABO Blood Group System was the first to be identified and is the most significant for transfusion practice It is the ONLY system that the reciprocal antibodies are consistently and predictably present in the sera of people who have had no exposure to human red cells ...
... The ABO Blood Group System was the first to be identified and is the most significant for transfusion practice It is the ONLY system that the reciprocal antibodies are consistently and predictably present in the sera of people who have had no exposure to human red cells ...
AFES 2015 Abstract Book V4 Final (English - pdf
... the product information currently provided by the manufacturer to verify appropriate dosage, method and duration of administration, and other relevant information. In all instances, it is the responsibility of the treating physician or other healthcare professional, relying on independent experience ...
... the product information currently provided by the manufacturer to verify appropriate dosage, method and duration of administration, and other relevant information. In all instances, it is the responsibility of the treating physician or other healthcare professional, relying on independent experience ...
(S) tet Resistance Determinant Element Containing the Tetracycline
... the latter explanation, as the 4.8-kb hybridizing HindIII fragment with the int/xis probe is the same size as one of the fragments when tet(S) is used as the probe, indicating that the tet(S) gene and one of the int/xis regions are linked. When pAM120 is used to probe the blots, HincII digestion sho ...
... the latter explanation, as the 4.8-kb hybridizing HindIII fragment with the int/xis probe is the same size as one of the fragments when tet(S) is used as the probe, indicating that the tet(S) gene and one of the int/xis regions are linked. When pAM120 is used to probe the blots, HincII digestion sho ...
gramene_ontologytutorial
... An Ontology is a glossary of keywords arranged in a structured order or a network based on the biological concepts ...
... An Ontology is a glossary of keywords arranged in a structured order or a network based on the biological concepts ...
Twinning and Embryonic Left-Right Asymmetry
... The geometrical invariance known as symmetry is a striking feature of developmental morphology during embryogenesis. The left-right axis of an animal's body plan is often thought of as being fundamentally different from the dorso-ventral and antero-posterior axes because of the symmetry which it exh ...
... The geometrical invariance known as symmetry is a striking feature of developmental morphology during embryogenesis. The left-right axis of an animal's body plan is often thought of as being fundamentally different from the dorso-ventral and antero-posterior axes because of the symmetry which it exh ...
PDF
... heterochromatic spreading (reviewed by Weiler and Wakimoto, 1995; Girton and Johansen, 2008). If JIL-1 had a crucial role in promoting transcription at a majority of genes by regulating transcriptional elongation, it is difficult to envisage how lethality can be rescued to near wild-type levels in t ...
... heterochromatic spreading (reviewed by Weiler and Wakimoto, 1995; Girton and Johansen, 2008). If JIL-1 had a crucial role in promoting transcription at a majority of genes by regulating transcriptional elongation, it is difficult to envisage how lethality can be rescued to near wild-type levels in t ...