genetic studies of the human complement c4 region in mhc class iii
... cells7. Complement plays an essential role in inflammation through the release of inflammatory mediators, which cause the contraction of smooth muscle cells and the increase of vascular permeability. Complement also participates in the generation of acquired immunity by lowering the threshold for ac ...
... cells7. Complement plays an essential role in inflammation through the release of inflammatory mediators, which cause the contraction of smooth muscle cells and the increase of vascular permeability. Complement also participates in the generation of acquired immunity by lowering the threshold for ac ...
A pair of Sox: distinct and overlapping functions of
... sox9ahi1134 mutants do, giving a curly-down body axis (Fig. 3A,C,E). This phenotype could result from the brief expression of sox9b in the notochord at about 20 hpf. Animals injected with sox9b MOs also show the curly-down phenotype, supporting this hypothesis (Fig. 3D). To understand the role of so ...
... sox9ahi1134 mutants do, giving a curly-down body axis (Fig. 3A,C,E). This phenotype could result from the brief expression of sox9b in the notochord at about 20 hpf. Animals injected with sox9b MOs also show the curly-down phenotype, supporting this hypothesis (Fig. 3D). To understand the role of so ...
functional analysis of chromatin assembly genes in tetrahymena
... The basic structural unit of chromatin is the nucleosome composed of ~147 base pairs of DNA wrapped around an octamer of histone proteins. Post-translational modifications such as histone acetylation or the substitution of histone variants in place of core histones have been implicated in various ch ...
... The basic structural unit of chromatin is the nucleosome composed of ~147 base pairs of DNA wrapped around an octamer of histone proteins. Post-translational modifications such as histone acetylation or the substitution of histone variants in place of core histones have been implicated in various ch ...
Retrograde Gbb signaling through the Bmp type 2
... signaling disrupted FMRFa expression. Initially, we employed an antibody derived against the peptide FMRFamide. This antibody likely recognizes several classes of FaRPs. As shown in Fig. 1 (compare A with B), we find that in crawling third instar wit mutants there is a specific disruption in the acc ...
... signaling disrupted FMRFa expression. Initially, we employed an antibody derived against the peptide FMRFamide. This antibody likely recognizes several classes of FaRPs. As shown in Fig. 1 (compare A with B), we find that in crawling third instar wit mutants there is a specific disruption in the acc ...
A long-term demasculinization of X
... on the X chromosome in comparisons of ovary versus testis and ovary versus accessory gland (OR range = 0.77–0.86, P < 6.53 3 103 ) (Fig. 2B,C). No significant departure from random chromosomal distribution, however, was observed for female-biased incRNAs derived from whole body female versus male c ...
... on the X chromosome in comparisons of ovary versus testis and ovary versus accessory gland (OR range = 0.77–0.86, P < 6.53 3 103 ) (Fig. 2B,C). No significant departure from random chromosomal distribution, however, was observed for female-biased incRNAs derived from whole body female versus male c ...
The genetic epidemiology of idiopathic scoliosis
... association was found for five genes (LOX, LOX1, LOX2, LOX3, LOX4) when common polymorphisms were verified in an American population (discovery cohort 138 cases/411 controls, replication cohort 400 cases/506 controls) [24]. Extracellular matrix degradation and remodeling are important for normal end ...
... association was found for five genes (LOX, LOX1, LOX2, LOX3, LOX4) when common polymorphisms were verified in an American population (discovery cohort 138 cases/411 controls, replication cohort 400 cases/506 controls) [24]. Extracellular matrix degradation and remodeling are important for normal end ...
The Toll immune-regulated Drosophila protein Fondue is involved in
... melanogaster that encodes an abundant hemolymph protein containing multiple repeat blocks. After knockdown of fon by RNAi, bead aggregation activity of larval hemolymph is strongly reduced, and wound closure is affected. fon is thus the second Drosophila gene after hemolectin (hml), for which a knoc ...
... melanogaster that encodes an abundant hemolymph protein containing multiple repeat blocks. After knockdown of fon by RNAi, bead aggregation activity of larval hemolymph is strongly reduced, and wound closure is affected. fon is thus the second Drosophila gene after hemolectin (hml), for which a knoc ...
View PDF - OMICS International
... by ABI Prism 3100 analyzer. The degree of the XCI in the digested DNA was calculated as follows: peak area of (XCm digested/non digested)/ (XCm digested/non digested)+(XCn digested/non digested) x 100. The results showed 2 peaks of different size indicating a different numbers of CAG repeats between ...
... by ABI Prism 3100 analyzer. The degree of the XCI in the digested DNA was calculated as follows: peak area of (XCm digested/non digested)/ (XCm digested/non digested)+(XCn digested/non digested) x 100. The results showed 2 peaks of different size indicating a different numbers of CAG repeats between ...
Analysis of DNA transcription termination sequences of gene coding
... In this work a phaC1-phaZ intergenic region from nineteen Pseudomonas strains was investigated (Figure 2). These regions are vastly different. The length of this region ranged from 60 bp (Pseudomonas putida AF150670) to 225 bp (Pseudomonas corrugata AY910767). In case of Pseudomonas USM4-55, Pseudom ...
... In this work a phaC1-phaZ intergenic region from nineteen Pseudomonas strains was investigated (Figure 2). These regions are vastly different. The length of this region ranged from 60 bp (Pseudomonas putida AF150670) to 225 bp (Pseudomonas corrugata AY910767). In case of Pseudomonas USM4-55, Pseudom ...
Recommended Breeding Policy for the LaPerm cat - Kia-Ora
... and carefully considered breeding decisions. There is a detailed description of ideal coat type in the standard of points. Coats should be curly or wavy with some frizziness in the coat, but not to the exclusion of any defined curls or waves. Good curls are preferable in longhaired LaPerms, especial ...
... and carefully considered breeding decisions. There is a detailed description of ideal coat type in the standard of points. Coats should be curly or wavy with some frizziness in the coat, but not to the exclusion of any defined curls or waves. Good curls are preferable in longhaired LaPerms, especial ...
Evolution of Mammalian KELL Blood Group Glycoproteins and
... heart, spleen and skeletal muscle [3,9]. The structures of the human KEL and the mouse Kel genes have been reported, containing 18 or 19 exons of DNA encoding KELL sequences [9,10,27,28]. The molecular basis of the major human KELL antigens has been determined, which result from KEL point mutations ...
... heart, spleen and skeletal muscle [3,9]. The structures of the human KEL and the mouse Kel genes have been reported, containing 18 or 19 exons of DNA encoding KELL sequences [9,10,27,28]. The molecular basis of the major human KELL antigens has been determined, which result from KEL point mutations ...
Effects of cadmium on the regulation of antioxidant enzyme activity
... The Kuroshio Research Group of the Asia-Pacific Ocean Research Center, National Sun Yat-sen University, Kaohsiung 80424, Taiwan ...
... The Kuroshio Research Group of the Asia-Pacific Ocean Research Center, National Sun Yat-sen University, Kaohsiung 80424, Taiwan ...
Genetic Control of Seed Shattering in Rice by the
... spikelets, except for the shattering defect and smaller seeds (Figures 1O and 1P; see Supplemental Figures 2E, 2L, 4A, and 4B online). The shat1 shat2 double mutant had a crook-neck-like rachilla (Figures 1U and 1V; see Supplemental Figure 2F online) and showed similar spikelet defects to those in s ...
... spikelets, except for the shattering defect and smaller seeds (Figures 1O and 1P; see Supplemental Figures 2E, 2L, 4A, and 4B online). The shat1 shat2 double mutant had a crook-neck-like rachilla (Figures 1U and 1V; see Supplemental Figure 2F online) and showed similar spikelet defects to those in s ...
Inquiry into Life Twelfth Edition
... folds – Prevents formation of a hairpin – This is part of the transcription termination signal which causes attenuation ...
... folds – Prevents formation of a hairpin – This is part of the transcription termination signal which causes attenuation ...
MicroRNAs: key participants in gene regulatory networks
... for miR165 encoded HD-Zip transcription factors. The potential complementary sites might explain the ectopic expression previously described for mutations in these genes. It seemed that complementarity to miR165 was required for confining these mRNA’s accumulation to the proper cell types [33]. Ta ...
... for miR165 encoded HD-Zip transcription factors. The potential complementary sites might explain the ectopic expression previously described for mutations in these genes. It seemed that complementarity to miR165 was required for confining these mRNA’s accumulation to the proper cell types [33]. Ta ...
genes code for ion channels, but 2 channelopathies (MASS1
... COMMENT. In this selected population that included infants in intensive care, a higher incidence of epilepsy than that seen in population-based studies could be expected. Multiple risk factors for neonatal seizures, and especially bacterial meningitis, are associated with a higher probability of dev ...
... COMMENT. In this selected population that included infants in intensive care, a higher incidence of epilepsy than that seen in population-based studies could be expected. Multiple risk factors for neonatal seizures, and especially bacterial meningitis, are associated with a higher probability of dev ...
- LSHTM Research Online
... strating frequent acquisition of genomic islands by horizontal transfer (8). The size and recombinogenic nature of the genome mean that our understanding of the survival and pathogenesis of this important bacterium at the genetic level is still rudimentary. The size and plasticity of the B. pseudom ...
... strating frequent acquisition of genomic islands by horizontal transfer (8). The size and recombinogenic nature of the genome mean that our understanding of the survival and pathogenesis of this important bacterium at the genetic level is still rudimentary. The size and plasticity of the B. pseudom ...
View PDF
... in the higher size region. In DM1 expansion analysis, TP-PCR had proven to be an accurate technique. Nevertheless, the presence of rare interruptions of the otherwise pure CTG repeat13, 20 may result in aberrant patterns or failure to detect expansions with TP-PCR21. Therefore, to exclude false-nega ...
... in the higher size region. In DM1 expansion analysis, TP-PCR had proven to be an accurate technique. Nevertheless, the presence of rare interruptions of the otherwise pure CTG repeat13, 20 may result in aberrant patterns or failure to detect expansions with TP-PCR21. Therefore, to exclude false-nega ...
Journal of Bacteriology
... added L-2,4-diaminobutyric acid. Taken together, our findings demonstrate that the pmx gene cluster is responsible for polymyxin biosynthesis. Since polymyxin was first isolated from Bacillus polymyxa in 1947 (1, 4, 47), at least 15 unique polymyxins have been reported (31, 49). Because of its excel ...
... added L-2,4-diaminobutyric acid. Taken together, our findings demonstrate that the pmx gene cluster is responsible for polymyxin biosynthesis. Since polymyxin was first isolated from Bacillus polymyxa in 1947 (1, 4, 47), at least 15 unique polymyxins have been reported (31, 49). Because of its excel ...
In-class assignment: Fukuda et al. (2016) paper
... XmXm embryos. Embryos that express Kdm4b and are treated with TSA have a more relaxed chromatin structure around Xist locus than mock-treated XmXm embryos. These embryos have a higher Xist expression and therefore are able to inactivate the chromosome. (The chromosome is more likely to be inactivate ...
... XmXm embryos. Embryos that express Kdm4b and are treated with TSA have a more relaxed chromatin structure around Xist locus than mock-treated XmXm embryos. These embryos have a higher Xist expression and therefore are able to inactivate the chromosome. (The chromosome is more likely to be inactivate ...
WHITE PANICLE1, a Val-tRNA Synthetase
... phenotype during early leaf development. Seedlings showing the severe albino phenotype (wp1s) died when they reached the four-leaf stage (Fig. 1A, a–b; Supplemental Figure S1A), while wp1 seedlings showing the weak virescent phenotype (wp1w) could reach the flowering stage when they displayed white p ...
... phenotype during early leaf development. Seedlings showing the severe albino phenotype (wp1s) died when they reached the four-leaf stage (Fig. 1A, a–b; Supplemental Figure S1A), while wp1 seedlings showing the weak virescent phenotype (wp1w) could reach the flowering stage when they displayed white p ...
The tightly regulated promoter of the xanA gene of
... genes of the purine degradation pathway, necessitating the specific UaY transcription factor and the AreA GATA factor. The promoter of the duplicated region is active ectopically and the difficulty in detecting an mRNA from the duplicated region is at least partially due to nonsense-mediated decay. ...
... genes of the purine degradation pathway, necessitating the specific UaY transcription factor and the AreA GATA factor. The promoter of the duplicated region is active ectopically and the difficulty in detecting an mRNA from the duplicated region is at least partially due to nonsense-mediated decay. ...
Application of the new manP counter-selection system for B. subtilis
... subtilis, iii) encodes an antibiotic resistance gene for selection in B. subtilis and iiii) ...
... subtilis, iii) encodes an antibiotic resistance gene for selection in B. subtilis and iiii) ...
A tandem repeat in decay accelerating factor 1 induced autoimmunity
... Although there is evidence that DAF mRNA stability can be affected by tissue specific factors [17] and inflammation [18], most studies suggest that expression is primarily modulated at transcription [15–17, 19, 20]. The human DAF promoter has been identified, the transcription start site mapped, and ...
... Although there is evidence that DAF mRNA stability can be affected by tissue specific factors [17] and inflammation [18], most studies suggest that expression is primarily modulated at transcription [15–17, 19, 20]. The human DAF promoter has been identified, the transcription start site mapped, and ...