Two-Component System of Mycobacterium Tuberculosis
... Under phosphate-starvation-induction conditions, the Response Regulator (RR) PhoP, and the histidine protein kinase (HK) PhoR, are involved in the induction of Pho-regulon genes including the phoPR operon and genes encoding the major vegetative alkaline phosphatases, phoA and phoB. The PhoP protein ...
... Under phosphate-starvation-induction conditions, the Response Regulator (RR) PhoP, and the histidine protein kinase (HK) PhoR, are involved in the induction of Pho-regulon genes including the phoPR operon and genes encoding the major vegetative alkaline phosphatases, phoA and phoB. The PhoP protein ...
Genetic polymorphism of epoxide hydrolase and glutathione S-transferase in COPD S-L. Cheng
... It is generally accepted that cigarette smoking is the most important risk factor for chronic obstructive pulmonary disease (COPD). Nevertheless, only 10–20% of chronic smokers develop the severe impairment of pulmonary function associated with COPD [1, 2]. This indicates the possible contribution o ...
... It is generally accepted that cigarette smoking is the most important risk factor for chronic obstructive pulmonary disease (COPD). Nevertheless, only 10–20% of chronic smokers develop the severe impairment of pulmonary function associated with COPD [1, 2]. This indicates the possible contribution o ...
Abundant Genetic Overlap between Blood Lipids and Immune
... Plasma concentrations of low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol and triglycerides (TG) are heritable risk factors for cardiovascular disease and important pharmacological targets for prevention strategies. Several lines of evidence suggest a relationshi ...
... Plasma concentrations of low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol and triglycerides (TG) are heritable risk factors for cardiovascular disease and important pharmacological targets for prevention strategies. Several lines of evidence suggest a relationshi ...
The Rh Antigen D: A Review for Clinicians
... • Ideally, D– patients should be transfused with D– RBC components. • A patient whose RBCs lack some D epitopes but still type D+ can make anti-D and should be transfused with D– RBC components. These RBCs type D+ with some anti-D from some clones and D– with other anti-D from others. • With certain ...
... • Ideally, D– patients should be transfused with D– RBC components. • A patient whose RBCs lack some D epitopes but still type D+ can make anti-D and should be transfused with D– RBC components. These RBCs type D+ with some anti-D from some clones and D– with other anti-D from others. • With certain ...
Standard
... not occur in all conditions in the spring mutants. It depends on long-day photoperiods but not on vernalisation. Isolation of flanking sequence tags and linkage analysis identified retroelement insertions at FTa1 that co-segregated with the early flowering phenotype in all three spring mutants. Thes ...
... not occur in all conditions in the spring mutants. It depends on long-day photoperiods but not on vernalisation. Isolation of flanking sequence tags and linkage analysis identified retroelement insertions at FTa1 that co-segregated with the early flowering phenotype in all three spring mutants. Thes ...
factor occupancy and gene expression Effects of sequence variation
... A complex interplay between transcription factors (TFs) and the genome regulates transcription. However, connecting variation in genome sequence with variation in TF binding and gene expression is challenging due to environmental differences between individuals and cell types. To address this proble ...
... A complex interplay between transcription factors (TFs) and the genome regulates transcription. However, connecting variation in genome sequence with variation in TF binding and gene expression is challenging due to environmental differences between individuals and cell types. To address this proble ...
factor occupancy and gene expression Effects of sequence variation
... A complex interplay between transcription factors (TFs) and the genome regulates transcription. However, connecting variation in genome sequence with variation in TF binding and gene expression is challenging due to environmental differences between individuals and cell types. To address this proble ...
... A complex interplay between transcription factors (TFs) and the genome regulates transcription. However, connecting variation in genome sequence with variation in TF binding and gene expression is challenging due to environmental differences between individuals and cell types. To address this proble ...
Genome Biology - Department of Computer Science and
... opportunity to investigate their underlying relationships with TFBSs [22, 23]. Many chromatin modifications have been shown to be associated with transcription activation and repression [3, 4]. Recent studies have shown that incorporating histone modification data improves prediction of TFBS in mous ...
... opportunity to investigate their underlying relationships with TFBSs [22, 23]. Many chromatin modifications have been shown to be associated with transcription activation and repression [3, 4]. Recent studies have shown that incorporating histone modification data improves prediction of TFBS in mous ...
no correlation between cyp17-34t/c polymorphism and severe acne
... All subjects were examined consecutively in our outpatient unit by dermatologists. Patients with acne venenata and acne cosmetica were excluded from the study. The clinical grade of acne was assessed based on the Consensus Conference on Acne Classification (Gollnick et al., 2003). According to these ...
... All subjects were examined consecutively in our outpatient unit by dermatologists. Patients with acne venenata and acne cosmetica were excluded from the study. The clinical grade of acne was assessed based on the Consensus Conference on Acne Classification (Gollnick et al., 2003). According to these ...
factor occupancy and gene expression Effects of
... A complex interplay between transcription factors (TFs) and the genome regulates transcription. However, connecting variation in genome sequence with variation in TF binding and gene expression is challenging due to environmental differences between individuals and cell types. To address this proble ...
... A complex interplay between transcription factors (TFs) and the genome regulates transcription. However, connecting variation in genome sequence with variation in TF binding and gene expression is challenging due to environmental differences between individuals and cell types. To address this proble ...
Genetic analysis of genes on the 4th chromosome of
... chromosome set. The chromocenter of D. virilis contains a very strongly staining material that he called α-heterochromatin that forms the pericentric, satellite-rich DNA. The classical view of β-heterochromatin put forward by Heitz is that it represents the transition between the α-heterochromatin a ...
... chromosome set. The chromocenter of D. virilis contains a very strongly staining material that he called α-heterochromatin that forms the pericentric, satellite-rich DNA. The classical view of β-heterochromatin put forward by Heitz is that it represents the transition between the α-heterochromatin a ...
Non-cell-autonomous regulation of root hair patterning genes by
... The establishment of a pattern of files forming root hairs and non-root hairs in the root epidermis is a wellstudied developmental model system (Schiefelbein et al., 2009; Tominaga-Wada et al., 2011; Grebe, 2012). Root hair cells (H-cells) develop from cell files over the cleft of two underlying cor ...
... The establishment of a pattern of files forming root hairs and non-root hairs in the root epidermis is a wellstudied developmental model system (Schiefelbein et al., 2009; Tominaga-Wada et al., 2011; Grebe, 2012). Root hair cells (H-cells) develop from cell files over the cleft of two underlying cor ...
The Mobile Genetic Element Alu in the Human Genome
... Only a small fraction of the human genome consists of functional, or protein-encoding, genes. If all the nucleotide information were translated, 10 9 amino acids, or approximately 3 million average-size proteins, would be encoded. Based on the fully sequenced genomes of simple organisms and consider ...
... Only a small fraction of the human genome consists of functional, or protein-encoding, genes. If all the nucleotide information were translated, 10 9 amino acids, or approximately 3 million average-size proteins, would be encoded. Based on the fully sequenced genomes of simple organisms and consider ...
X chromosome inactivation- Review
... region in Xist gene and is required for X inactivation Model- Mutually exclusive binding of blocking factor to Xce on one X, and of initiator factor to Xist on other X Marsupials and in mice extraembyonic tissues- paternal X always inactivated in females ...
... region in Xist gene and is required for X inactivation Model- Mutually exclusive binding of blocking factor to Xce on one X, and of initiator factor to Xist on other X Marsupials and in mice extraembyonic tissues- paternal X always inactivated in females ...
D. melanogaster - GEP Community Server
... Retrieve the sequences of the initial exons from the Transcript Details tab of the Gene Record Finder Use placement of the flanking exons to reduce the size of the search region if possible Increase sensitivity of nucleotide searches Change Program Selection to blastn Change Word size to 7 Change Ma ...
... Retrieve the sequences of the initial exons from the Transcript Details tab of the Gene Record Finder Use placement of the flanking exons to reduce the size of the search region if possible Increase sensitivity of nucleotide searches Change Program Selection to blastn Change Word size to 7 Change Ma ...
Rather than test an unmapped gene successively for linkage to... groups, it is advantageous to test all linkage groups in... alcoy David Perkins
... How to use alcoy for linkage group assignment. David Perkins Background Rather than test an unmapped gene successively for linkage to markers in each of the seven linkage groups, it is advantageous to test all linkage groups in a single cross. Efficiency is greatly increased by using as tester a str ...
... How to use alcoy for linkage group assignment. David Perkins Background Rather than test an unmapped gene successively for linkage to markers in each of the seven linkage groups, it is advantageous to test all linkage groups in a single cross. Efficiency is greatly increased by using as tester a str ...
Genetic aspects of chronic pancreatitis
... be deleterious and lead to autodigestion and AP. Today multiple mechanisms are known to prevent premature uncontrolled activation of the digestive enzyme cascade within the pancreas and to protect the organ from self-destruction [22, 23]. These include (i) synthesis of digestive enzymes as inactive ...
... be deleterious and lead to autodigestion and AP. Today multiple mechanisms are known to prevent premature uncontrolled activation of the digestive enzyme cascade within the pancreas and to protect the organ from self-destruction [22, 23]. These include (i) synthesis of digestive enzymes as inactive ...
1 Depleting gene activities in early Drosophila embryos
... D-raf mutant offspring derived from heterozygous females die during larval-pupal development. However, embryos derived from D-raf mutant GLCs exhibit two classes of phenotypes: embryos that receive a wild type (WT) paternal copy display a “terminal class” phenotype, with the acron and telson missing ...
... D-raf mutant offspring derived from heterozygous females die during larval-pupal development. However, embryos derived from D-raf mutant GLCs exhibit two classes of phenotypes: embryos that receive a wild type (WT) paternal copy display a “terminal class” phenotype, with the acron and telson missing ...
Depleting Gene Activities in Early Drosophila Embryos
... 1994). D-raf mutant offspring derived from heterozygous females die during larval–pupal development. However, embryos derived from D-raf mutant GLCs exhibit two classes of phenotypes: embryos that receive a WT paternal copy display a “terminal class” phenotype, with the acron and telson missing, bec ...
... 1994). D-raf mutant offspring derived from heterozygous females die during larval–pupal development. However, embryos derived from D-raf mutant GLCs exhibit two classes of phenotypes: embryos that receive a WT paternal copy display a “terminal class” phenotype, with the acron and telson missing, bec ...
Multiple Domains Exist within the Upstream Activator
... 4A). These data indicate that sequences present between -222 and -193, within pAIRa45, augment the palindrome to provide full activity. A subset of these additional sequences 5' to the palindrome contained within pHin38 [the 5' palindrome augmenting sequence (5' PAS)] cannot augment the activity of ...
... 4A). These data indicate that sequences present between -222 and -193, within pAIRa45, augment the palindrome to provide full activity. A subset of these additional sequences 5' to the palindrome contained within pHin38 [the 5' palindrome augmenting sequence (5' PAS)] cannot augment the activity of ...
Updated slides on gene prediction
... • Systematically deleted nucleotides from DNA – Single and double deletions dramatically altered protein product – Effects of triple deletions were minor – Conclusion: every triplet of nucleotides, each codon, codes for exactly one amino acid in a protein ...
... • Systematically deleted nucleotides from DNA – Single and double deletions dramatically altered protein product – Effects of triple deletions were minor – Conclusion: every triplet of nucleotides, each codon, codes for exactly one amino acid in a protein ...
Structure, expression and chromosomal location of the Oct
... other members of the POU family. After digestion with PstI, a restriction fragment length polymorphism (RFLP) was identified in C57BL/6 (B6) versus AKR and A / J . This allowed use of the congenic chromosomes listed in Fig. 1A (Flaherty et al., 1990). Whereas, the B6.K1 and B6.K3 recombinants place ...
... other members of the POU family. After digestion with PstI, a restriction fragment length polymorphism (RFLP) was identified in C57BL/6 (B6) versus AKR and A / J . This allowed use of the congenic chromosomes listed in Fig. 1A (Flaherty et al., 1990). Whereas, the B6.K1 and B6.K3 recombinants place ...
Compound leaves: equal to the sum of their parts?
... phenotype – the number of small intercalary leaflets is slightly reduced, which can be interpreted as a reduction in complexity (Molinero-Rosales et al., 1999). Known expression patterns of FLO/LFY orthologs in vegetative apices have been summarized recently (Busch and Gleissberg, 2003). In species ...
... phenotype – the number of small intercalary leaflets is slightly reduced, which can be interpreted as a reduction in complexity (Molinero-Rosales et al., 1999). Known expression patterns of FLO/LFY orthologs in vegetative apices have been summarized recently (Busch and Gleissberg, 2003). In species ...
New functions of the Drosophila rhomboid gene
... vein material or blisters, were recovered at high frequency (Fig. 2B-D). This is consistent with previous data suggesting that even low levels of ectopic rho expression during wing development generate excess vein phenotypes (Sturtevant et al., 1993). Some lines exhibited localized wing venation def ...
... vein material or blisters, were recovered at high frequency (Fig. 2B-D). This is consistent with previous data suggesting that even low levels of ectopic rho expression during wing development generate excess vein phenotypes (Sturtevant et al., 1993). Some lines exhibited localized wing venation def ...
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... RA-Hox1 network appears to have played key roles in these evolutionary innovations crucial for acquiring the chordate body plan. Our study also suggests that Ci-Hox1 in the endoderm functions in ASP formation. In Ciona, the inductive signal for ASP formation is thought to be mediated by fibroblast g ...
... RA-Hox1 network appears to have played key roles in these evolutionary innovations crucial for acquiring the chordate body plan. Our study also suggests that Ci-Hox1 in the endoderm functions in ASP formation. In Ciona, the inductive signal for ASP formation is thought to be mediated by fibroblast g ...