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... (Cai and Cullen, 2007; Mineno et al., 2006). Both the full-length RNA and the miRNA have been identified in marsupials, suggesting a strong functional conservation throughout evolution (Smits et al., 2008). H19 is strongly expressed during mouse embryogenesis in mesoderm and endoderm-derived tissues ...
... (Cai and Cullen, 2007; Mineno et al., 2006). Both the full-length RNA and the miRNA have been identified in marsupials, suggesting a strong functional conservation throughout evolution (Smits et al., 2008). H19 is strongly expressed during mouse embryogenesis in mesoderm and endoderm-derived tissues ...
MicroRNA Analysis
... signaling that occurs in mid-life. The miRNA control of such systems as the cell cycle, DNA repair, oxidative stress responses and apoptosis, has been shown to become abnormally expressed in mid-life. It is highly likely that continued research will reveal important associations with the aging proce ...
... signaling that occurs in mid-life. The miRNA control of such systems as the cell cycle, DNA repair, oxidative stress responses and apoptosis, has been shown to become abnormally expressed in mid-life. It is highly likely that continued research will reveal important associations with the aging proce ...
Integrated genome sequence and linkage map of physic nut
... and 0.746 Mbp, respectively, which are approximately 1.8 and 46.8 times longer, respectively, than the reported physic nut genome (Hirakawa et al., 2012). As the result of short contigs and scaffolds, too many predicted genes in their study were fragmented. Only 17 Mbp (6%) of their assembly (but ab ...
... and 0.746 Mbp, respectively, which are approximately 1.8 and 46.8 times longer, respectively, than the reported physic nut genome (Hirakawa et al., 2012). As the result of short contigs and scaffolds, too many predicted genes in their study were fragmented. Only 17 Mbp (6%) of their assembly (but ab ...
Molecular Imaging - Engineering Computing Facility
... amplification have already been alluded to previously. Three molecular imaging signal amplification methods are currently used: trapping, gene expression and activation. Trapping refers to the process of confining imaging probes within the cell or on the cell surface by means of one-way receptors, o ...
... amplification have already been alluded to previously. Three molecular imaging signal amplification methods are currently used: trapping, gene expression and activation. Trapping refers to the process of confining imaging probes within the cell or on the cell surface by means of one-way receptors, o ...
Altered Pax gene expression in murine notochord mutants: the
... portion of the neural tube. D, dermatome; N, neural tube. (E) The T gene at d 11.5 pc is expressed in the tailbud and the notochord. T, tail bud; C, notochord. Fig. 4. Marker gene expression in Brachyury embryos. (A) Pax-1 expression in + / + (left) and T C / T c (right) embryos at d 9.5 pc. Note th ...
... portion of the neural tube. D, dermatome; N, neural tube. (E) The T gene at d 11.5 pc is expressed in the tailbud and the notochord. T, tail bud; C, notochord. Fig. 4. Marker gene expression in Brachyury embryos. (A) Pax-1 expression in + / + (left) and T C / T c (right) embryos at d 9.5 pc. Note th ...
Regulation of Na/K-ATPase β1 -subunit gene
... Ca2+ and in the force of contraction. This effect on cardiac contractility is the basis of the major therapeutic use of these drugs in the treatment of congestive heart failure. Recently, using cultured neonatal rat cardiac myocytes, we showed that partial inhibition of Na/K-ATPase by ouabain also a ...
... Ca2+ and in the force of contraction. This effect on cardiac contractility is the basis of the major therapeutic use of these drugs in the treatment of congestive heart failure. Recently, using cultured neonatal rat cardiac myocytes, we showed that partial inhibition of Na/K-ATPase by ouabain also a ...
DYAD in meiotic chromosome organisation - Development
... region of genomic DNA which was then digested with a panel of restriction enzymes, and electrophoresed on a gel to identify polymorphisms between the Ler and No-O ecotypes and in some cases between Ler and Col-O. Recombinants north and south of dyad were first screened and identified with respect to ...
... region of genomic DNA which was then digested with a panel of restriction enzymes, and electrophoresed on a gel to identify polymorphisms between the Ler and No-O ecotypes and in some cases between Ler and Col-O. Recombinants north and south of dyad were first screened and identified with respect to ...
Selecting an Ontology for Biomedical Text Mining He Tan, Patrick Lambrix Abstract
... access to text, natural language processing, and information integration. Developers of text mining applications often look for appropriate ontologies that can be integrated into their systems, rather than develop new ontologies from scratch. The choice of ontology may, however, have a major impact ...
... access to text, natural language processing, and information integration. Developers of text mining applications often look for appropriate ontologies that can be integrated into their systems, rather than develop new ontologies from scratch. The choice of ontology may, however, have a major impact ...
LEADING ARTICLE Concurrent disruption of p16INK4a and
... Alterations of several oncogenes and tumor suppressor genes have been demonstrated in NHL.3 As in many other types of cancer, the most commonly altered targets reported in NHL are the genes encoding the tumor suppressors p16INK4a and p53.4–22 These proteins are key components of the machinery that c ...
... Alterations of several oncogenes and tumor suppressor genes have been demonstrated in NHL.3 As in many other types of cancer, the most commonly altered targets reported in NHL are the genes encoding the tumor suppressors p16INK4a and p53.4–22 These proteins are key components of the machinery that c ...
Complete Characterization of the 3 Mouse Hereditary Hemochromatosis HFE Gene and
... ABSTRACT: The human HFE gene was identified in 1996 as the gene whose mutations are responsible for hereditary hemochromatosis in most patients. Expression analysis by Northern blot indicated that the gene was approximately 4.1 kb in length. However, the cDNA reported was only 2716 bp. These results ...
... ABSTRACT: The human HFE gene was identified in 1996 as the gene whose mutations are responsible for hereditary hemochromatosis in most patients. Expression analysis by Northern blot indicated that the gene was approximately 4.1 kb in length. However, the cDNA reported was only 2716 bp. These results ...
Quantitative expression of cholera toxin mRNA in Vibrio cholerae
... genes encode proteins for replication and activation (RstA), integration (RstB), regulation of gene expression (RstR) and anti-repression (RstC). It has been shown that RS1 has a positive effect on the ctxAB genes, resulting in increased production of CT by modulation of the RS1 genomic segment (Dav ...
... genes encode proteins for replication and activation (RstA), integration (RstB), regulation of gene expression (RstR) and anti-repression (RstC). It has been shown that RS1 has a positive effect on the ctxAB genes, resulting in increased production of CT by modulation of the RS1 genomic segment (Dav ...
PHI-Canto video tutorial text - PHI-base
... Here is a summary for the annotations made for the # Tri5Delta genotype. # There is one annotation under PHI phenotype. A Visual check can be made here and annotations # can be edited, deleted or duplicated using the options on the right. # At this point the author may only be making one annotation ...
... Here is a summary for the annotations made for the # Tri5Delta genotype. # There is one annotation under PHI phenotype. A Visual check can be made here and annotations # can be edited, deleted or duplicated using the options on the right. # At this point the author may only be making one annotation ...
Mechanisms of translational regulation in bacteria
... Many functional related genes in bacteria are combined in operons and transcribed as a single polycistronic mRNA, thus being strongly co-regulated on the transcriptional level. However, even translation may be coupled in these mRNAs leading to an even stronger correlation of expression levels. Here, ...
... Many functional related genes in bacteria are combined in operons and transcribed as a single polycistronic mRNA, thus being strongly co-regulated on the transcriptional level. However, even translation may be coupled in these mRNAs leading to an even stronger correlation of expression levels. Here, ...
Microbiology
... 2003, 2005). MutS is involved in the methyl-directed recognition of DNA mismatches related to replication, which include base mismatches and small insertion and deletion mispairs (Modrich, 1991). The expression of mismatch repair systems can be negatively influenced by stress or growth-limiting cond ...
... 2003, 2005). MutS is involved in the methyl-directed recognition of DNA mismatches related to replication, which include base mismatches and small insertion and deletion mispairs (Modrich, 1991). The expression of mismatch repair systems can be negatively influenced by stress or growth-limiting cond ...
Estimates of Selection and Gene Flow From Measures of
... and that u rz 2.6 km. In erato, the shapes of the clines agreed with that expected on the basis of dominance. Heliconius melpomene has a nearly coincident hybrid zone. In this species, cline widths at four major color pattern loci varied between 1 1.7 and 13.4km. Pairwise gametic correlations peaked ...
... and that u rz 2.6 km. In erato, the shapes of the clines agreed with that expected on the basis of dominance. Heliconius melpomene has a nearly coincident hybrid zone. In this species, cline widths at four major color pattern loci varied between 1 1.7 and 13.4km. Pairwise gametic correlations peaked ...
Math of Genetics - College of William & Mary
... Pepper color is controlled by two different genes The first gene controls the expression of red pigment The dominant allele (R) indicates the presence of red ...
... Pepper color is controlled by two different genes The first gene controls the expression of red pigment The dominant allele (R) indicates the presence of red ...
Control of Lysogenization by Phage P22. II. Mutations (clyA) in the c1 Gene that Cause Increased Lysogenization
... tests are done under conditions in which each parent was infected at @I) into the ely-non-permissive host DB7000 and each parent carried a mutation in a P22 late gene. In every case. one parent carried a 5-am mutation carried an a-am mutation. In this way, only cells that were co-infected by each a ...
... tests are done under conditions in which each parent was infected at @I) into the ely-non-permissive host DB7000 and each parent carried a mutation in a P22 late gene. In every case. one parent carried a 5-am mutation carried an a-am mutation. In this way, only cells that were co-infected by each a ...
Chapter 44 Self Test (EOC)
... Answer—Brachyury, Tbx5, and others, are examples of genes that have a defined function in a basal set of taxa, and in more derived taxa the function switches. In the case of these two genes, the new function is central to defining what is novel or derived in the new taxa. Co-opting is the use of an ...
... Answer—Brachyury, Tbx5, and others, are examples of genes that have a defined function in a basal set of taxa, and in more derived taxa the function switches. In the case of these two genes, the new function is central to defining what is novel or derived in the new taxa. Co-opting is the use of an ...
Inverse correlation between SMN1 and SMN2 copy numbers
... because of SMN1 gene deletions or gene conversions from SMN1 to SMN2, which has only one base difference in coding sequence from SMN1. Using SMN gene dosage analysis, we determined the copy numbers of SMN1 and SMN2 in the general population as well as in SMA patients and carriers. Increased SMN1 cop ...
... because of SMN1 gene deletions or gene conversions from SMN1 to SMN2, which has only one base difference in coding sequence from SMN1. Using SMN gene dosage analysis, we determined the copy numbers of SMN1 and SMN2 in the general population as well as in SMA patients and carriers. Increased SMN1 cop ...
T1 transgenic tobacco plants
... cultivar was found to have the best resistance to weevils while LC1 and LVN99 cultivars have low resistant ability. 2. ZmDEF1 gene (DNA)isolated from studied maize cultivars has 345 bp, it is made of an intron with 102 bp between two exons; ZmDEF1 gene (cDNA) has 243 bp codifying 80 amino acids. 3. ...
... cultivar was found to have the best resistance to weevils while LC1 and LVN99 cultivars have low resistant ability. 2. ZmDEF1 gene (DNA)isolated from studied maize cultivars has 345 bp, it is made of an intron with 102 bp between two exons; ZmDEF1 gene (cDNA) has 243 bp codifying 80 amino acids. 3. ...
Guidelines for interpretation of 16S rRNA gene sequence
... interpretation of their large sequence dataset. On the other hand, Janda and Abbott suggested that a minimum of .99 %, and ideally .99.5 %, sequence similarity be used for species identification in their recommended guidelines (Janda & Abbott, 2007). Although different studies have identified groups ...
... interpretation of their large sequence dataset. On the other hand, Janda and Abbott suggested that a minimum of .99 %, and ideally .99.5 %, sequence similarity be used for species identification in their recommended guidelines (Janda & Abbott, 2007). Although different studies have identified groups ...
A versatile toolbox for PCR-based tagging of yeast genes: new
... protein complex purification (Gavin et al., 2002; Ho et al., 2002), as well as for single gene-function analysis. The strategy requires: (a) a pair of primers that contain within their 5 region sequences of homology to the genomic target location; and (b) PCR-cassettes (also termed ‘modules’) that ...
... protein complex purification (Gavin et al., 2002; Ho et al., 2002), as well as for single gene-function analysis. The strategy requires: (a) a pair of primers that contain within their 5 region sequences of homology to the genomic target location; and (b) PCR-cassettes (also termed ‘modules’) that ...
A Conserved Molecular Framework for Compound Leaf Development
... In A. caerula, AcNAM and AcCUC3 are expressed at the boundaries between leaf primordia (lp) and the meristem (m) during the formation of the rosette leaves (A, B) and after bolting (C). In the floral meristem (fm), AcNAM marks the boundary of the numerous stamen primordia (stp, D). In the vegetative ...
... In A. caerula, AcNAM and AcCUC3 are expressed at the boundaries between leaf primordia (lp) and the meristem (m) during the formation of the rosette leaves (A, B) and after bolting (C). In the floral meristem (fm), AcNAM marks the boundary of the numerous stamen primordia (stp, D). In the vegetative ...
Additional Table 1. Genotype and phenotype of the
... kb, 45,265,479-45,828,359, genomic build hg 18). Two genes involved, one has an OMIM entry (PRKCE ). Chr. 20p21.1 del (approximately 218 kb, 14,823,878-15,041,954, genomic yes build hg 18). One gene involved (MACROD2 ). No parental studies were performed. The clinical significance of these copy numb ...
... kb, 45,265,479-45,828,359, genomic build hg 18). Two genes involved, one has an OMIM entry (PRKCE ). Chr. 20p21.1 del (approximately 218 kb, 14,823,878-15,041,954, genomic yes build hg 18). One gene involved (MACROD2 ). No parental studies were performed. The clinical significance of these copy numb ...