org.Dr.eg.db
... assigned in the literature, users are cautioned that this map may produce multiple matching results for a single gene symbol. Users should map back from the entrez gene IDs produced to determine which result is the one they want when this happens. Because of this problem with redundant assigment of ...
... assigned in the literature, users are cautioned that this map may produce multiple matching results for a single gene symbol. Users should map back from the entrez gene IDs produced to determine which result is the one they want when this happens. Because of this problem with redundant assigment of ...
invited review
... rabbit isolated perfused renal proximal tubules, the maximum rate of active glucose transport in the convoluted tubule (S1/S2) was an order of magnitude greater than that in the late straight tubule. The Michaelis-Menten coefficient value (Km) for glucose was ⬃2 mM in S1/S2 and ⬃0.5 mM in S3 (1). Th ...
... rabbit isolated perfused renal proximal tubules, the maximum rate of active glucose transport in the convoluted tubule (S1/S2) was an order of magnitude greater than that in the late straight tubule. The Michaelis-Menten coefficient value (Km) for glucose was ⬃2 mM in S1/S2 and ⬃0.5 mM in S3 (1). Th ...
Familial Adenomatous Polyposis (FAP)
... An ileo-rectal anastomosis (IRA) involves removing the large bowel and attaching the small bowel to the rectum. The rectum may develop polyps so this must be examined at least once a year to prevent a cancer starting there. In a pouch operation the lining of the rectum and the colon are removed. A p ...
... An ileo-rectal anastomosis (IRA) involves removing the large bowel and attaching the small bowel to the rectum. The rectum may develop polyps so this must be examined at least once a year to prevent a cancer starting there. In a pouch operation the lining of the rectum and the colon are removed. A p ...
![[PDF]](http://s1.studyres.com/store/data/008788917_1-5177913eca4d392ae5a4e07ae9753abf-300x300.png)
[PDF]
... and applied to mutagenesis to define the pathways that lead to triplet repeat instability. However, it is possible that there may exist interspecies differences between human and mouse in this regard and that humans lack mechanisms, present in mice, which stabilize the repeats. The timing and molecu ...
... and applied to mutagenesis to define the pathways that lead to triplet repeat instability. However, it is possible that there may exist interspecies differences between human and mouse in this regard and that humans lack mechanisms, present in mice, which stabilize the repeats. The timing and molecu ...
Difference in leptin response to a high
... 12 lean and 12 obese men for determination of glucose, insulin and leptin. The TEF was calculated as postprandial energy expenditure minus fasting energy expenditure, as measured by indirect calorimetry. Fasting plasma glucose levels were similar in lean and obese men, and increased in the same way ...
... 12 lean and 12 obese men for determination of glucose, insulin and leptin. The TEF was calculated as postprandial energy expenditure minus fasting energy expenditure, as measured by indirect calorimetry. Fasting plasma glucose levels were similar in lean and obese men, and increased in the same way ...
Imprinting in the endosperm: a possible role in preventing wide
... placenta, are regulated by a range of epigenetic mechanisms that are globally termed imprinting. Imprinted genes are characterized by their uniparental expression, the other parental allele being silenced. Normal development of the endosperm thus requires a highly specific balance of gene expression ...
... placenta, are regulated by a range of epigenetic mechanisms that are globally termed imprinting. Imprinted genes are characterized by their uniparental expression, the other parental allele being silenced. Normal development of the endosperm thus requires a highly specific balance of gene expression ...
Azza Ahmed Ibrahim Abo senna_GST paper
... DNA damage in the hemopoietic precursor cell is the essential prerequisite for the development of leukemia and the body has developed a series of mechanisms aimed at preventing such damage. Cytogenetic analysis in acute leukemia has revealed a great number of non-random chromosome abnormalities. In ...
... DNA damage in the hemopoietic precursor cell is the essential prerequisite for the development of leukemia and the body has developed a series of mechanisms aimed at preventing such damage. Cytogenetic analysis in acute leukemia has revealed a great number of non-random chromosome abnormalities. In ...
Fulltext - Jultika
... I wish to express my sincere thanks to my supervisor, Docent Leena Ala-Kokko, for always having time to advise me, and sometimes even to help in the practical lab work, for her everlasting optimism, for arranging an opportunity for me to work at the Center for Gene Therapy in Philadelphia for two su ...
... I wish to express my sincere thanks to my supervisor, Docent Leena Ala-Kokko, for always having time to advise me, and sometimes even to help in the practical lab work, for her everlasting optimism, for arranging an opportunity for me to work at the Center for Gene Therapy in Philadelphia for two su ...
105 - Heritable Diseases of Connective Tissue
... result in disproportionate short stature. Until the early 1960s, most individuals with short stature were considered to have pituitary dwarfism, achondroplasia (short-limb dwarfism), or Morquio disease (short-trunked dwarfism). Presently, there are more than 450 well-characterized disorders that are ...
... result in disproportionate short stature. Until the early 1960s, most individuals with short stature were considered to have pituitary dwarfism, achondroplasia (short-limb dwarfism), or Morquio disease (short-trunked dwarfism). Presently, there are more than 450 well-characterized disorders that are ...
Polygenes and Modifier Genes for Tetracycline and
... on a lawn of that same strain did not increase its level of resistance to Tet. This means that a ‘double dose effect’ does not occur. The tet in 6T20, MT93 and TM14 DNA preparations has additive effects with the mtr in 4B10, increasing its level of resistance from 0.3 to 0.6 ,ug ml-l. The same effec ...
... on a lawn of that same strain did not increase its level of resistance to Tet. This means that a ‘double dose effect’ does not occur. The tet in 6T20, MT93 and TM14 DNA preparations has additive effects with the mtr in 4B10, increasing its level of resistance from 0.3 to 0.6 ,ug ml-l. The same effec ...
Non-conflict theories for the evolution of genomic imprinting
... egg. Such experiments had universally failed until normal oocytes fused with oocytes doubly deleted in the H19 differentially methylated region and the Dlk1–Dio3 differentially methylated region were fused and brought to term (Kawahara et al., 2007). This absence implies that both maternal and pater ...
... egg. Such experiments had universally failed until normal oocytes fused with oocytes doubly deleted in the H19 differentially methylated region and the Dlk1–Dio3 differentially methylated region were fused and brought to term (Kawahara et al., 2007). This absence implies that both maternal and pater ...
Genetics of host response in leprosy
... account for the major clinical differences observed among patients; (ii) epidemiological studies have been reporting consistently that contacts exhibit the highest risk of developing the disease (household contacts with close consanguineous relationship to the index case are at the highest risk);2 ( ...
... account for the major clinical differences observed among patients; (ii) epidemiological studies have been reporting consistently that contacts exhibit the highest risk of developing the disease (household contacts with close consanguineous relationship to the index case are at the highest risk);2 ( ...
Number 48, 2001 35
... the premeiotic phase of the sexual cycle (Selker 1990, Annu. Rev. Genet. 24:597-613) offers a reasonable explanation for this phenomenon. Segmental duplications typically cover 10-50% of a chromosome and will include several essential genes. Selker proposed that the impaired fertility of such crosse ...
... the premeiotic phase of the sexual cycle (Selker 1990, Annu. Rev. Genet. 24:597-613) offers a reasonable explanation for this phenomenon. Segmental duplications typically cover 10-50% of a chromosome and will include several essential genes. Selker proposed that the impaired fertility of such crosse ...
PAX6 mRNA Transcript Analysis in Various Ocular/Non
... patterns for each specific tissue type (Figure 1A). As a primary attempt three samples of ocular tissues such as lens epithelium, normal WBC lymphocytes, and the HeLa RNA were subjected to amplify the PAX6 gene using 5’ paired domain primer. When the RT-PCR products were run on 2.5% agarose gel the ...
... patterns for each specific tissue type (Figure 1A). As a primary attempt three samples of ocular tissues such as lens epithelium, normal WBC lymphocytes, and the HeLa RNA were subjected to amplify the PAX6 gene using 5’ paired domain primer. When the RT-PCR products were run on 2.5% agarose gel the ...
Linköping University Post Print Segment-specific Neuronal Sub-type Specification by the Integration of
... genes act in three different ways. Posteriorly, Pbx/Meis and posterior Hox genes block lineage progression within an early temporal window, by triggering cell cycle exit. Because Ap neurons are generated late in the thoracic 5–6 lineage, this prevents generation of Ap cluster cells in the abdomen. T ...
... genes act in three different ways. Posteriorly, Pbx/Meis and posterior Hox genes block lineage progression within an early temporal window, by triggering cell cycle exit. Because Ap neurons are generated late in the thoracic 5–6 lineage, this prevents generation of Ap cluster cells in the abdomen. T ...
PDF
... and polarized light sensors (Hardie, 1985). According to their differentiated function, R1-6 innervate the first OL neuropil, which is the lamina, whereas R7 and R8 axons run across the lamina to innervate the neuropil beneath, which is the medulla. Next, the lobula and lobula plate (together called ...
... and polarized light sensors (Hardie, 1985). According to their differentiated function, R1-6 innervate the first OL neuropil, which is the lamina, whereas R7 and R8 axons run across the lamina to innervate the neuropil beneath, which is the medulla. Next, the lobula and lobula plate (together called ...
Age-related macular degeneration: a perspective on genetic studies
... homozygous for the risk alleles (representing a tyrosine–histidine change at amino acid 402) have a 7.4-fold increased likelihood of AMD.28 These studies confirm an initial hypothesis, which established that chronic inflammation involving the complement pathway could contribute to disease progressio ...
... homozygous for the risk alleles (representing a tyrosine–histidine change at amino acid 402) have a 7.4-fold increased likelihood of AMD.28 These studies confirm an initial hypothesis, which established that chronic inflammation involving the complement pathway could contribute to disease progressio ...
htp Pseudomonas aeruginosa AMANDA SWANEPOEL
... as those with cancer or AIDS and those suffering from cystic fibrosis and burns (Van Delden and Iglewski, 1998; Ramsey and Wozniak, 2005), but it has also been shown to infect plants and insects (Schroth et al., 1992; Rahme et al., 1995). The success of P. aeruginosa in colonizing these diverse envi ...
... as those with cancer or AIDS and those suffering from cystic fibrosis and burns (Van Delden and Iglewski, 1998; Ramsey and Wozniak, 2005), but it has also been shown to infect plants and insects (Schroth et al., 1992; Rahme et al., 1995). The success of P. aeruginosa in colonizing these diverse envi ...
Vascular Endothelial Growth Factor and Its Receptors in Embryonic
... (2) embryonic development is rapid, with much of it occurring within 6 days postfertilization (Langheinrich, 2003); (3) zebrafish embryos are transparent, allowing visualization of the zebrafish cardiovascular system, including the heart and circulation of the blood; (4) zebrafish embryos are extrac ...
... (2) embryonic development is rapid, with much of it occurring within 6 days postfertilization (Langheinrich, 2003); (3) zebrafish embryos are transparent, allowing visualization of the zebrafish cardiovascular system, including the heart and circulation of the blood; (4) zebrafish embryos are extrac ...
Untitled - System Components
... Modular pleiotropy: modular pleiotropy describes when a gene or genes have multiple phenotypic effects only indirectly by modifying the functional expression of the module in which they have a role. Module: a module is group of functionally related genes that interact with each other to control inte ...
... Modular pleiotropy: modular pleiotropy describes when a gene or genes have multiple phenotypic effects only indirectly by modifying the functional expression of the module in which they have a role. Module: a module is group of functionally related genes that interact with each other to control inte ...
Detection and analysis of disease-associated single nucleotide
... containing more than 50 kinds of experimentally validated PTMs and predicted PTMs. While previous studies considered phosphorylation, PTM-SNP can examine multiple PTMs simultaneously. We also matched PTMSNPs with various disease-associated SNPs based on GWAS to find disease-associated PTM-SNPs. The ...
... containing more than 50 kinds of experimentally validated PTMs and predicted PTMs. While previous studies considered phosphorylation, PTM-SNP can examine multiple PTMs simultaneously. We also matched PTMSNPs with various disease-associated SNPs based on GWAS to find disease-associated PTM-SNPs. The ...
Involvement of Sox1, 2 and 3 in the early and subsequent molecular
... followed by a linker carrying stop codons in all three frames. In the SOX2∆N35 deletion, a Kozak sequence (Kozak, 1989) and a methionine codon were placed to the 5′ of the EcoRI site. The deletions are indicated by the amino acid residues that were removed. GAL4 fusion constructs were made by joinin ...
... followed by a linker carrying stop codons in all three frames. In the SOX2∆N35 deletion, a Kozak sequence (Kozak, 1989) and a methionine codon were placed to the 5′ of the EcoRI site. The deletions are indicated by the amino acid residues that were removed. GAL4 fusion constructs were made by joinin ...
fulltext - DiVA portal
... Background: Analysis of the Escherichia coli collection of reference strains (ECOR) for the presence of the gene locus clyA, which encodes the pore-forming protein ClyA (cytolysin A), revealed that a non-functional clyA locus is common among certain extraintestinal pathogenic E. coli (ExPEC). In fac ...
... Background: Analysis of the Escherichia coli collection of reference strains (ECOR) for the presence of the gene locus clyA, which encodes the pore-forming protein ClyA (cytolysin A), revealed that a non-functional clyA locus is common among certain extraintestinal pathogenic E. coli (ExPEC). In fac ...
Recurrent Pregnancy Loss and Its Relation to Combined Parental
... RPL is classically defined as the occurrence of three or more consecutive losses of clinically recognized pregnancies prior to the 20th week of gestation (ectopic and molar pregnancies are not included). The ASRM defines RPL as two or more failed pregnancies (by ultrasound or histopathological exami ...
... RPL is classically defined as the occurrence of three or more consecutive losses of clinically recognized pregnancies prior to the 20th week of gestation (ectopic and molar pregnancies are not included). The ASRM defines RPL as two or more failed pregnancies (by ultrasound or histopathological exami ...