Gene Section ALDOB (aldolase B, fructose-bisphosphate) Atlas of Genetics and Cytogenetics
... Tolan DR. Spatial clustering of isozyme-specific residues reveals unlikely determinants of isozyme specificity in fructose1,6-bisphosphate aldolase. J Biol Chem. 2003 May ...
... Tolan DR. Spatial clustering of isozyme-specific residues reveals unlikely determinants of isozyme specificity in fructose1,6-bisphosphate aldolase. J Biol Chem. 2003 May ...
Genetic studies of psoriasis and psoriatic arthritis
... occupational aspects. Psoriasis patients suffer impaired quality of life similar to or worse than patients with other chronic diseases such as ischemic heart disease and diabetes (Finlay et al. 1987). Over the past 20 years, our understanding of the disease mechanisms has advanced significantly and ...
... occupational aspects. Psoriasis patients suffer impaired quality of life similar to or worse than patients with other chronic diseases such as ischemic heart disease and diabetes (Finlay et al. 1987). Over the past 20 years, our understanding of the disease mechanisms has advanced significantly and ...
Unit II presentation
... provides reducing power in form of NADPH • NADPH serves as an electron donor for enzymatic reactions essential in biosynthetic pathways • Its production is crucial to protection of cells from oxidative stress ...
... provides reducing power in form of NADPH • NADPH serves as an electron donor for enzymatic reactions essential in biosynthetic pathways • Its production is crucial to protection of cells from oxidative stress ...
Gene Name
... multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesterol efflux pump in the cellular lipid removal pathway. Mutations in this gene have been associated with Tangier's disease and familial high-density lipoprotein deficiency. Actinin, alpha 1. Alpha actinin ...
... multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesterol efflux pump in the cellular lipid removal pathway. Mutations in this gene have been associated with Tangier's disease and familial high-density lipoprotein deficiency. Actinin, alpha 1. Alpha actinin ...
Biology 30
... A healthy female Labrador retriever has won several ribbons for her appearance in dog shows. She was mated with two healthy male Labrador retrievers. In the two litters produced, some of the offspring had hemophilia and others were normal. ...
... A healthy female Labrador retriever has won several ribbons for her appearance in dog shows. She was mated with two healthy male Labrador retrievers. In the two litters produced, some of the offspring had hemophilia and others were normal. ...
Review: Is genetic screening for hemochromatosis worthwhile?
... detecting subjects with delayed or incomplete penetrance, allowing diagnosis at an early age and treatment to prevent clinically significant iron overload [62]. However, not all subjects with iron overload carry the C282Y mutation. This mutation is mainly found in Caucasians. This limits the applicat ...
... detecting subjects with delayed or incomplete penetrance, allowing diagnosis at an early age and treatment to prevent clinically significant iron overload [62]. However, not all subjects with iron overload carry the C282Y mutation. This mutation is mainly found in Caucasians. This limits the applicat ...
Linking Cognitive Neuroscience and Molecular Genetics: New Perspectives from Williams... Ursula Bellugi and Marie St. George (Eds.)
... Figure 1) because yeast artificial chromosome (YAC) arrays of this region were highly rearranged and deleted ( http://www.genet.sickkids.on.ca/chromosome7). Forty-five of the initial 233 BACs mapping to chromosome 7 were located on band 7q11.2, of which 30 generated single and 15 generated large or ...
... Figure 1) because yeast artificial chromosome (YAC) arrays of this region were highly rearranged and deleted ( http://www.genet.sickkids.on.ca/chromosome7). Forty-five of the initial 233 BACs mapping to chromosome 7 were located on band 7q11.2, of which 30 generated single and 15 generated large or ...
Publication - The University of Texas Health Science Center at
... increased AIF-1 expression in the infiltrating cells within lesions [54–56]. A recent study demonstrated that AIF-1 promoted T-cell infiltration and induced the expression types I and III collagen and cytokines by normal dermal fibroblasts, providing additional evidence for a role of AIF-1 in scleroder ...
... increased AIF-1 expression in the infiltrating cells within lesions [54–56]. A recent study demonstrated that AIF-1 promoted T-cell infiltration and induced the expression types I and III collagen and cytokines by normal dermal fibroblasts, providing additional evidence for a role of AIF-1 in scleroder ...
Making Headway: The Roles of Hox Genes and Neural
... regions of the mature adult brain[2,3,4,5,6,7,8,9]. The segmental organization of the hindbrain presages the establishment of an anatomical and functional registration between individual rhombomeres, cranial ganglia, branchiomotor nerves, and the migration pathways of cranial neural crest cells into ...
... regions of the mature adult brain[2,3,4,5,6,7,8,9]. The segmental organization of the hindbrain presages the establishment of an anatomical and functional registration between individual rhombomeres, cranial ganglia, branchiomotor nerves, and the migration pathways of cranial neural crest cells into ...
Association of Interleukin-1 Receptor Antagonist Gene 86bp VNTR
... Interleukin-1 (IL-1) is a pro-inflammatory cytokine with widespread biological activities that plays an important role in inflammatory and immune-mediated diseases. This cytokine is regulated partly by interleukin-1 receptor antagonist (IL-1Ra) that inhibits IL-1 activity through binding to the IL-1 ...
... Interleukin-1 (IL-1) is a pro-inflammatory cytokine with widespread biological activities that plays an important role in inflammatory and immune-mediated diseases. This cytokine is regulated partly by interleukin-1 receptor antagonist (IL-1Ra) that inhibits IL-1 activity through binding to the IL-1 ...
Genetic Evidence for a Silent SUC Gene in Yeast.
... and need not be in the center of the gene. (c) A suco allele is shown as a SUC locus that contains no DNA related to the SUC+ gene; no implications are intended regarding the presence or absence of sequences normally adjacent to the SUC+ gene. recovered; the presence of the suc2-215am allele in this ...
... and need not be in the center of the gene. (c) A suco allele is shown as a SUC locus that contains no DNA related to the SUC+ gene; no implications are intended regarding the presence or absence of sequences normally adjacent to the SUC+ gene. recovered; the presence of the suc2-215am allele in this ...
Spatially restricted domains of homeo-gene
... a segmentally restricted manner and that their expression presages morphological differentiation of segmental structures (e.g. Levine et a|.1983; Akam & Martinez-Arias, 1985; Chadwick & McGinnis, 1987). The discovery of homeo-genes in a wide variety of metazoz, including vertebrates, led to the sugg ...
... a segmentally restricted manner and that their expression presages morphological differentiation of segmental structures (e.g. Levine et a|.1983; Akam & Martinez-Arias, 1985; Chadwick & McGinnis, 1987). The discovery of homeo-genes in a wide variety of metazoz, including vertebrates, led to the sugg ...
ABSTRACT Using a bioinformatics approach to identify genes that
... The project herein describes a process that can be used to identify genes that have possible association with RP through comparing similar gene sets and identifying genes in those similar gene sets that are currently not associated with RP. These genes can then be further studied to determine their ...
... The project herein describes a process that can be used to identify genes that have possible association with RP through comparing similar gene sets and identifying genes in those similar gene sets that are currently not associated with RP. These genes can then be further studied to determine their ...
Development of a repressible mycobacterial
... these tools proved to be quite useful, they have the disadvantage that Tc functions as an inducer of gene expression and has therefore to be removed to silence the gene under investigation. For this reason Guo et al. (13) developed a modified system using a mutated TetR able to bind tetO only in the ...
... these tools proved to be quite useful, they have the disadvantage that Tc functions as an inducer of gene expression and has therefore to be removed to silence the gene under investigation. For this reason Guo et al. (13) developed a modified system using a mutated TetR able to bind tetO only in the ...
Ophthalmic Genetics Update Genetics and Genomics of
... which encodes the unique N-terminal domain that is required both for proper enzyme activation and for substrate recognition and binding.45 Abnormalities were not observed in the highly conserved C- terminal of the protein where the catalytic domains are located. The risk allele G of SNP rs1048661 (R ...
... which encodes the unique N-terminal domain that is required both for proper enzyme activation and for substrate recognition and binding.45 Abnormalities were not observed in the highly conserved C- terminal of the protein where the catalytic domains are located. The risk allele G of SNP rs1048661 (R ...
The Ehlers–Danlos syndrome, a disorder with many faces
... Lack of this segment leads to a deficient processing of the N-propeptide of type I collagen. The clinical hallmark of this EDS variant is congenital bilateral hip dislocation. The phenotype comprises also severe generalized joint hypermobility (Fig. 4) with recurrent dislocations, hyperextensible, b ...
... Lack of this segment leads to a deficient processing of the N-propeptide of type I collagen. The clinical hallmark of this EDS variant is congenital bilateral hip dislocation. The phenotype comprises also severe generalized joint hypermobility (Fig. 4) with recurrent dislocations, hyperextensible, b ...
PW_dp
... – accounts for heterogeneity in gene – Immediate gene-level interpretation •Cons: – disregards regulatory (often non-genic) information when based on location based ...
... – accounts for heterogeneity in gene – Immediate gene-level interpretation •Cons: – disregards regulatory (often non-genic) information when based on location based ...
Head induction in the chick - Max-Planck
... of RNA is shown in the following four lanes for the corresponding stages (glyceraldehyde-3-phosphate dehydrogenase GAPDH). The amplified product of the GANF RNA is shown on the right for the corresponding stages. At early streak stage (HH2), no GANF transcripts can be found. About 10 to 12 hours lat ...
... of RNA is shown in the following four lanes for the corresponding stages (glyceraldehyde-3-phosphate dehydrogenase GAPDH). The amplified product of the GANF RNA is shown on the right for the corresponding stages. At early streak stage (HH2), no GANF transcripts can be found. About 10 to 12 hours lat ...
Gene Section PAX8 (paired box 8) Atlas of Genetics and Cytogenetics
... transcription of its target-genes, such as TG, TPO and NIS. Marked phenotypic variability has been found within affected families, suggesting variable penetrance and expressivity of PAX8 gene defects. Some PAX8 mutations cause congenital hypothyroidism, while others mildly reduce thyroid hormone lev ...
... transcription of its target-genes, such as TG, TPO and NIS. Marked phenotypic variability has been found within affected families, suggesting variable penetrance and expressivity of PAX8 gene defects. Some PAX8 mutations cause congenital hypothyroidism, while others mildly reduce thyroid hormone lev ...
Report Number of Nuclear Divisions in the Drosophila Blastoderm
... RNAs [9] and zygotic gene expression [10, 11] are involved. The zinc finger Vielfältig (Vfl) controls expression of many early zygotic genes [12, 13], including the mitotic inhibitor frühstart [14, 15]. The functional relationship of these pathways and the mechanism for triggering the cell-cycle p ...
... RNAs [9] and zygotic gene expression [10, 11] are involved. The zinc finger Vielfältig (Vfl) controls expression of many early zygotic genes [12, 13], including the mitotic inhibitor frühstart [14, 15]. The functional relationship of these pathways and the mechanism for triggering the cell-cycle p ...
Journal Club 3
... White: Mutant (dormancy regulon knockout) All samples grown in low O2 induced dormant state Wildtype showed 200 fold greater viability at 40 and 50 day time points compared to mutant ...
... White: Mutant (dormancy regulon knockout) All samples grown in low O2 induced dormant state Wildtype showed 200 fold greater viability at 40 and 50 day time points compared to mutant ...
org.Mm.eg.db
... assigned in the literature, users are cautioned that this map may produce multiple matching results for a single gene symbol. Users should map back from the entrez gene IDs produced to determine which result is the one they want when this happens. Because of this problem with redundant assigment of ...
... assigned in the literature, users are cautioned that this map may produce multiple matching results for a single gene symbol. Users should map back from the entrez gene IDs produced to determine which result is the one they want when this happens. Because of this problem with redundant assigment of ...
Recruitment of CRABS CLAW to promote nectary development
... Fahn’s (Fahn, 1953) argument of an evolutionary acrocentripetal movement of nectary position within angiosperms (Fig. 1). In general, nectaries are not well differentiated in basal angiosperms. Nymphaeaceae and Illiciaceae in the ANITA grade have nectaries on perianth parts, and Amborella generates ...
... Fahn’s (Fahn, 1953) argument of an evolutionary acrocentripetal movement of nectary position within angiosperms (Fig. 1). In general, nectaries are not well differentiated in basal angiosperms. Nymphaeaceae and Illiciaceae in the ANITA grade have nectaries on perianth parts, and Amborella generates ...
Rosana Segovia HGT - Repositorio Digital USFQ
... The growing presence of multi-drug resistant phenotypes in Enterobacteriaceae that are associated with clinical cases of urinary tract infection, pneumonia, meningitis, and bacteremia have been well established (5-6, 13, 18). In addition, it is known that this increase occurs primarily through clona ...
... The growing presence of multi-drug resistant phenotypes in Enterobacteriaceae that are associated with clinical cases of urinary tract infection, pneumonia, meningitis, and bacteremia have been well established (5-6, 13, 18). In addition, it is known that this increase occurs primarily through clona ...
A gain of function mutation causing skeletal overgrowth in the
... We localized the rapunzelc14 mutation to linkage group (LG) 16 by centromere linkage analysis (Johnson et al., 1996) using simple sequence repeat (SSR) markers (Shimoda et al., 1999). SSR markers were then used to finely map the rapunzelc14 mutation (780 meioses with zero recombinations). In addition ...
... We localized the rapunzelc14 mutation to linkage group (LG) 16 by centromere linkage analysis (Johnson et al., 1996) using simple sequence repeat (SSR) markers (Shimoda et al., 1999). SSR markers were then used to finely map the rapunzelc14 mutation (780 meioses with zero recombinations). In addition ...