... occasion offers, to make several statements on this phase of the subject. I hold that heterosis is not a unitary phenomenon, but a complex series of phenomena for which no single cause or mechanism can be properly assumed to apply to all cases. The early hypothesis of DOCTOR EASTand myself that hete ...
PDF
... cDNA was prepared from 2 g of total RNA isolated with TRIzol reagent (Invitrogen, Carlsbad, CA) and treated with DNase (Roche, Mannheim, Germany) as described (Konopova and Jindra, 2007). cDNA samples diluted 5-fold with water were subjected to standard PCR reactions with Taq DNA polymerase (Unis, ...
... cDNA was prepared from 2 g of total RNA isolated with TRIzol reagent (Invitrogen, Carlsbad, CA) and treated with DNase (Roche, Mannheim, Germany) as described (Konopova and Jindra, 2007). cDNA samples diluted 5-fold with water were subjected to standard PCR reactions with Taq DNA polymerase (Unis, ...
gsea user guide
... dataset. For example, before running hierarchical clustering, you might remove genes that have low variance across the dataset. This prevents flat genes from driving the clustering result and improves processing time by focusing on a smaller number of interesting genes. The GSEA algorithm does not f ...
... dataset. For example, before running hierarchical clustering, you might remove genes that have low variance across the dataset. This prevents flat genes from driving the clustering result and improves processing time by focusing on a smaller number of interesting genes. The GSEA algorithm does not f ...
Deciphering the Galaxy Guppy phenotype
... orientation to the snakeskin pattern in the peduncle. I have seen guppies without the vertical bands called Galaxies, and I have seen guppies with vertical bands in the peduncle called “cobras.” There is obviously a blurred boundary between very similar phenotypes. The vertical bars are often treate ...
... orientation to the snakeskin pattern in the peduncle. I have seen guppies without the vertical bands called Galaxies, and I have seen guppies with vertical bands in the peduncle called “cobras.” There is obviously a blurred boundary between very similar phenotypes. The vertical bars are often treate ...
PDF
... (the prolonged cold of winter) and long days (see Amasino, 2010). Arabidopsis provides a useful guide to the types of genes/proteins that regulate flowering and, although there are important differences, the molecular mechanisms controlling seasonal flowering responses of grasses can be viewed as vari ...
... (the prolonged cold of winter) and long days (see Amasino, 2010). Arabidopsis provides a useful guide to the types of genes/proteins that regulate flowering and, although there are important differences, the molecular mechanisms controlling seasonal flowering responses of grasses can be viewed as vari ...
no isthmus and pax2.1 in zebrafish tubulogenesis
... pax5 and pax8 genes have been grouped into a common subfamily based on their sequence similarity and expression pattern. pax2/pax5/pax8 members share in common the paired domain, an octapeptide motif, and a partial homeodomain. Mice homozygous for a null mutation in pax2 display severe defects in ge ...
... pax5 and pax8 genes have been grouped into a common subfamily based on their sequence similarity and expression pattern. pax2/pax5/pax8 members share in common the paired domain, an octapeptide motif, and a partial homeodomain. Mice homozygous for a null mutation in pax2 display severe defects in ge ...
SERIES ‘‘GENETICS OF ASTHMA AND COPD IN THE POSTGENOME ERA’’
... relevant to the chronic airway events that underlie the human disease [46]. A radical new approach is needed to properly understand the combination of factors necessary for the cause(s) of chronic asthma and its progression beyond the simple concept of sequential allergen sensitisation and exposure. ...
... relevant to the chronic airway events that underlie the human disease [46]. A radical new approach is needed to properly understand the combination of factors necessary for the cause(s) of chronic asthma and its progression beyond the simple concept of sequential allergen sensitisation and exposure. ...
WEREWOLF, a Regulator of Root Hair Pattern
... long days and short days (Suárez-López et al., 2001). However, CO mRNA expressed at night does not cause the activation of FT, because CO protein is degraded in the dark (Valverde et al., 2004). Therefore, flowering is delayed in short days due to the absence of FT. In contrast, mutations in genes ...
... long days and short days (Suárez-López et al., 2001). However, CO mRNA expressed at night does not cause the activation of FT, because CO protein is degraded in the dark (Valverde et al., 2004). Therefore, flowering is delayed in short days due to the absence of FT. In contrast, mutations in genes ...
CONSERVATION AND DIVERGENCE IN MOLECULAR
... axis depends upon the activity of the dorsal transcription factor. During oogenesis, a molecular cue localized around the oocyte nucleus determines follicle cells lying on one side of the oocyte as dorsal. This leads to the development of follicle cells on the other side of the oocyte as ventral, vi ...
... axis depends upon the activity of the dorsal transcription factor. During oogenesis, a molecular cue localized around the oocyte nucleus determines follicle cells lying on one side of the oocyte as dorsal. This leads to the development of follicle cells on the other side of the oocyte as ventral, vi ...
Regulation of Ovule Development
... 2B) (Liu et al., 2000). Although both of these genes are known to repress AGAMOUS (AG) genetically, this loss of the medial domain is not an effect of AG overexpression. Rather, ANT and LUG seem to share a vital role in promoting cell proliferation in the marginal tissues of the pistil, specifically ...
... 2B) (Liu et al., 2000). Although both of these genes are known to repress AGAMOUS (AG) genetically, this loss of the medial domain is not an effect of AG overexpression. Rather, ANT and LUG seem to share a vital role in promoting cell proliferation in the marginal tissues of the pistil, specifically ...
chicken.db - Bioconductor
... indicates the chromosome. Due to inconsistencies that may exist at the time the object was built, these vectors may contain more than one chromosome and/or location. If the chromosomal location is unknown, the vector will contain an NA. Chromosomal locations on both the sense and antisense strands a ...
... indicates the chromosome. Due to inconsistencies that may exist at the time the object was built, these vectors may contain more than one chromosome and/or location. If the chromosomal location is unknown, the vector will contain an NA. Chromosomal locations on both the sense and antisense strands a ...
New and Redesigned pRS Plasmid Shuttle Vectors for Genetic
... on the plasmid pUC19 (Gietz and Sugino 1988), whereas the pRS series uses a hybrid backbone built using either the pBluescript or pBluescriptII polylinker/multiple cloning site (MCS) ligated to the pBluescribe replication origin (Christianson et al. 1992; Sikorski and Hieter 1989). Compared with ol ...
... on the plasmid pUC19 (Gietz and Sugino 1988), whereas the pRS series uses a hybrid backbone built using either the pBluescript or pBluescriptII polylinker/multiple cloning site (MCS) ligated to the pBluescribe replication origin (Christianson et al. 1992; Sikorski and Hieter 1989). Compared with ol ...
LATHYROIDES, encoding a WUSCHEL
... During organ development, many key regulators have been identified in plant genomes, which play conserved role among plant species to control the organ identities and/or determine the organ size and shape. It is intriguing that whether these key regulators can acquire diverse function and be integra ...
... During organ development, many key regulators have been identified in plant genomes, which play conserved role among plant species to control the organ identities and/or determine the organ size and shape. It is intriguing that whether these key regulators can acquire diverse function and be integra ...
No Slide Title
... • Imprinted genes are expressed differently depending on whether they are inherited through the maternal or paternal parent. ...
... • Imprinted genes are expressed differently depending on whether they are inherited through the maternal or paternal parent. ...
MRSA - Infectious Diseases
... mec gene complex (mecI, mecR1, mecA) + ccr gene complex (ccrA, ccrB) (responsible for mobility and insertion of the gene complex) + other transposons, plasmids ...
... mec gene complex (mecI, mecR1, mecA) + ccr gene complex (ccrA, ccrB) (responsible for mobility and insertion of the gene complex) + other transposons, plasmids ...
Pet_SUMO manual
... protein (Saitoh et al., 1997). Smt3, hereby referred to as SUMO, is a member of a ubiquitin-like protein family that regulates several cellular processes including apoptosis, nuclear transport, and cell cycle progression (Muller et al., 2001). Like ubiquitin, SUMO covalently attaches to lysine side ...
... protein (Saitoh et al., 1997). Smt3, hereby referred to as SUMO, is a member of a ubiquitin-like protein family that regulates several cellular processes including apoptosis, nuclear transport, and cell cycle progression (Muller et al., 2001). Like ubiquitin, SUMO covalently attaches to lysine side ...
Puffs and PCR: the in vivo dynamics of early gene
... of the salivary gland and showed once more that although many early puffs were common to the two tissues there were differences in their response which might find their counterparts at the molecular level. This idea has been developed in the tissue coordination model (Burtis et al., 1990; Thummel et ...
... of the salivary gland and showed once more that although many early puffs were common to the two tissues there were differences in their response which might find their counterparts at the molecular level. This idea has been developed in the tissue coordination model (Burtis et al., 1990; Thummel et ...
Pultz, M. A., and Baker, B. S.
... Most sexually dimorphic aspects of differentiation are under dsx control, directly or indirectly (reviewed in Burtis and Wolfner, 1992). However, some aspects of nervous system development (including behavior) have recently been found to be regulated only by tra, not by dsx or ix (Lawrence and Johns ...
... Most sexually dimorphic aspects of differentiation are under dsx control, directly or indirectly (reviewed in Burtis and Wolfner, 1992). However, some aspects of nervous system development (including behavior) have recently been found to be regulated only by tra, not by dsx or ix (Lawrence and Johns ...
Gene Ontology (GO) Tutorial
... Occasionally, one will come across gene products that have been annotated to Process, Function, and/or Component Unknown. These three terms are used when a curator has looked over the available literature and has found that none of it is adequate to assign a term. A good example is Dab2ip. As shown ...
... Occasionally, one will come across gene products that have been annotated to Process, Function, and/or Component Unknown. These three terms are used when a curator has looked over the available literature and has found that none of it is adequate to assign a term. A good example is Dab2ip. As shown ...
Chapter 13 - Microbial Genetics
... preQ: If a mutation eliminates binding of inducer to the repressor, but the repressor still binds to DNA; A) The lac operon will be always induced B) The lac operon will never be induced C) The lac operon will be induced whenever glucose is absent, regardless of the presence or absence of lactose D ...
... preQ: If a mutation eliminates binding of inducer to the repressor, but the repressor still binds to DNA; A) The lac operon will be always induced B) The lac operon will never be induced C) The lac operon will be induced whenever glucose is absent, regardless of the presence or absence of lactose D ...
Bilateral Macronodular Adrenal Hyperplasia (BMAH)
... apparently sporadic BMAH and in large families with BMAH - Armadillo repeat containing 5(ARMC5) o Located on Chromosome 16p11.2 o Unknown function; behaved as a tumor suppressor gene, second hit is needed for disease development o Its inactivation decreased the expression of MC2R and steroidogenic e ...
... apparently sporadic BMAH and in large families with BMAH - Armadillo repeat containing 5(ARMC5) o Located on Chromosome 16p11.2 o Unknown function; behaved as a tumor suppressor gene, second hit is needed for disease development o Its inactivation decreased the expression of MC2R and steroidogenic e ...
Resveratrol Opportunism: What Is the Science Behind the Claims?
... many times more bioavailable than resveratrol itself, and, therefore, less of it is required for therapeutic benefits to accrue. Published literature that purportedly supports this claim has been cited, but closer scrutiny reveals that all but 1 of the studies used in vitro assays of specific cell l ...
... many times more bioavailable than resveratrol itself, and, therefore, less of it is required for therapeutic benefits to accrue. Published literature that purportedly supports this claim has been cited, but closer scrutiny reveals that all but 1 of the studies used in vitro assays of specific cell l ...
Single Nucleotide Polymorphism (SNP) of the Endothelial Nitric
... The x2 test was used to compare the observed frequencies to predicted frequencies (not shown) by the Hardy-Weinberg equilibrium among patient and control study populations. ...
... The x2 test was used to compare the observed frequencies to predicted frequencies (not shown) by the Hardy-Weinberg equilibrium among patient and control study populations. ...
Trichothiodystrophy: Update on the sulfur
... transcription initiation and DNA repair is damaged. Beyond deficiency in the NER pathway, it is hypothesized that basal transcription may be altered leading to decreased transcription of specific genes. Depressed RNA synthesis may account for some clinical features, such as growth retardation, neuro ...
... transcription initiation and DNA repair is damaged. Beyond deficiency in the NER pathway, it is hypothesized that basal transcription may be altered leading to decreased transcription of specific genes. Depressed RNA synthesis may account for some clinical features, such as growth retardation, neuro ...
Exclusion of known corneal dystrophy genes in an autosomal
... biomicroscopy to be predominantly in the posterior corneal stroma. The majority of patients are asymptomatic. Recurrent erosions are not a typical feature, although photophobia is reported [3,4]. In vivo confocal microscopy of fleck dystrophies highlights small bright deposits in and around keratocy ...
... biomicroscopy to be predominantly in the posterior corneal stroma. The majority of patients are asymptomatic. Recurrent erosions are not a typical feature, although photophobia is reported [3,4]. In vivo confocal microscopy of fleck dystrophies highlights small bright deposits in and around keratocy ...