Affymetrix Software User Manuals
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... written instructions provided by Affymetrix. You understand and agree that, except as expressly set forth in the Affymetrix terms and conditions, no right or license to any patent or other intellectual property owned or licensable by Affymetrix is conveyed or implied by this Affymetrix product. In p ...
as Adobe PDF - Edinburgh Research Explorer
... currently too few characterized target genes and CRMs known to make accurate models about Biniou’s direct regulatory role; only three direct target genes have been identified to date. Biniou provides positive feedback regulation to bagpipe during trunk VM specification (Zaffran et al. 2001). The two ...
... currently too few characterized target genes and CRMs known to make accurate models about Biniou’s direct regulatory role; only three direct target genes have been identified to date. Biniou provides positive feedback regulation to bagpipe during trunk VM specification (Zaffran et al. 2001). The two ...
PPT
... G3P dehydrogenase-like beta grasp HSP70 C-term. fragment long helices oligomers Leu-zipper ...
... G3P dehydrogenase-like beta grasp HSP70 C-term. fragment long helices oligomers Leu-zipper ...
Regulation of limb bud initiation and limbtype
... bud will appear and, thus, their identity (Cohn et al., 1997; Cohn and Tickle, 1999) (Fig. 1A). For example, Hoxc4-5 is expressed mostly in the mesenchyme of the presumptive forelimb area (Savard et al., 1988; Tabin, 1989; Molven et al., 1990; Burke et al., 1995), Hoxc9, Hoxc10, Hoxc11 are, predomin ...
... bud will appear and, thus, their identity (Cohn et al., 1997; Cohn and Tickle, 1999) (Fig. 1A). For example, Hoxc4-5 is expressed mostly in the mesenchyme of the presumptive forelimb area (Savard et al., 1988; Tabin, 1989; Molven et al., 1990; Burke et al., 1995), Hoxc9, Hoxc10, Hoxc11 are, predomin ...
Inheritance involved in the pathogenesis of idiopathic scoliosis
... idiopathic curvature have not been identified. This is most likely a consequence of several factors, including inconsistent pedigree construction between human studies, an arbitrary consensus threshold for proband curve magnitude that may obscure true heritability, and the lack of a genetic model. I ...
... idiopathic curvature have not been identified. This is most likely a consequence of several factors, including inconsistent pedigree construction between human studies, an arbitrary consensus threshold for proband curve magnitude that may obscure true heritability, and the lack of a genetic model. I ...
jing is required for wing development and to establish the
... for the second chromosome, are described in FlyBase and Bloomington Stock Center web sites. jing22F3 and jing47H6 alleles were obtained from Denise Montell's lab (LIU and MONTELL 2001). Since these two mutations were not molecularly characterized, we sequenced the jing genomic region from homozygote ...
... for the second chromosome, are described in FlyBase and Bloomington Stock Center web sites. jing22F3 and jing47H6 alleles were obtained from Denise Montell's lab (LIU and MONTELL 2001). Since these two mutations were not molecularly characterized, we sequenced the jing genomic region from homozygote ...
Dickkopf1 Is Required for Embryonic Head Induction
... 1997b; Wodarz and Nusse, 1998). Cerberus is a multifunctional inhibitor of BMP, Nodal, and Wnt signals (Piccolo et al., 1999). Wif-1 contains domains with homology to EGF repeats (Hsieh et al., 1999). These Wnt inhibitors have been implicated in the repression of the canonical Wnt/-catenin signalin ...
... 1997b; Wodarz and Nusse, 1998). Cerberus is a multifunctional inhibitor of BMP, Nodal, and Wnt signals (Piccolo et al., 1999). Wif-1 contains domains with homology to EGF repeats (Hsieh et al., 1999). These Wnt inhibitors have been implicated in the repression of the canonical Wnt/-catenin signalin ...
Gene Section MLL (myeloid/lymphoid or mixed lineage leukemia) Atlas of Genetics and Cytogenetics
... (as breakpoints are variable, this is only an example). ...
... (as breakpoints are variable, this is only an example). ...
Molecular cloning of a laccase isozyme gene from
... inducible promoter. The native Ple. sajor-caju laccase signal sequence was effective in directing the secretion of lac4 expressed in Pic. pastoris. The control of media pH and temperature was found to be important in obtaining sufficient quantities of the protein to allow purification and subsequent ...
... inducible promoter. The native Ple. sajor-caju laccase signal sequence was effective in directing the secretion of lac4 expressed in Pic. pastoris. The control of media pH and temperature was found to be important in obtaining sufficient quantities of the protein to allow purification and subsequent ...
A caudal mRNA gradient controls posterior development in the wasp
... highlighted several common and different pathways to pattern the embryo (reviewed by Liu and Kaufman, 2005). We have chosen to study the wasp Nasonia, an important model system with which compare early development that is functionally accessible, through both genetics and parental RNAi (Pultz and Le ...
... highlighted several common and different pathways to pattern the embryo (reviewed by Liu and Kaufman, 2005). We have chosen to study the wasp Nasonia, an important model system with which compare early development that is functionally accessible, through both genetics and parental RNAi (Pultz and Le ...
C 2: A A -
... enzymes are widely distributed in Enterobacteriaceae, whereas OXA-type and CARBtype beta-lactamases are rare (27). The few reports of P. aeruginosa strains harbouring TEM and SHV-type genes may have several explanations. Firstly, the rarity of narrowspectrum TEM and SHV-type enzymes may limit antibi ...
... enzymes are widely distributed in Enterobacteriaceae, whereas OXA-type and CARBtype beta-lactamases are rare (27). The few reports of P. aeruginosa strains harbouring TEM and SHV-type genes may have several explanations. Firstly, the rarity of narrowspectrum TEM and SHV-type enzymes may limit antibi ...
DNA supercoiling factor contributes to dosage
... were less pronounced and varied among the lines tested. No significant effect on females was observed for the 2-1 transgenic line (Fig. 1B). In an experiment with the 2-1 line, we changed the temperature from 25°C to 18°C because the activation levels in the GAL4/UAS system are dramatically affected ...
... were less pronounced and varied among the lines tested. No significant effect on females was observed for the 2-1 transgenic line (Fig. 1B). In an experiment with the 2-1 line, we changed the temperature from 25°C to 18°C because the activation levels in the GAL4/UAS system are dramatically affected ...
Collagens, modifying enzymes and their mutations in humans, flies
... divided into several subfamilies on the basis of these assemblies or other features (Figure 1). Collagen types I – XIX have been discussed in many previous reviews [1 – 4], whereas collagen types XX– XXVII (Table 1) have been reported only during the past three years [7– 14]. Some collagens have a r ...
... divided into several subfamilies on the basis of these assemblies or other features (Figure 1). Collagen types I – XIX have been discussed in many previous reviews [1 – 4], whereas collagen types XX– XXVII (Table 1) have been reported only during the past three years [7– 14]. Some collagens have a r ...
Genomic analysis of the histidine kinase family in bacteria and
... to respond to diverse environmental stimuli. HKs possess a conserved domain (H-box region) which contains the site of phosphorylation and an ATP-binding kinase domain. In this study, a genomic approach was taken to analyse the HK family in bacteria and archaea. Based on phylogenetic analysis, differ ...
... to respond to diverse environmental stimuli. HKs possess a conserved domain (H-box region) which contains the site of phosphorylation and an ATP-binding kinase domain. In this study, a genomic approach was taken to analyse the HK family in bacteria and archaea. Based on phylogenetic analysis, differ ...
here - Glaucoma Genetics Lab
... Purpose: To both characterize the clinical features of large primary open angle glaucoma (POAG) pedigree from a village in southern India and to investigate the genetic basis of their disease. Materials and methods: Eighty-four members of a large pedigree received complete eye examinations including ...
... Purpose: To both characterize the clinical features of large primary open angle glaucoma (POAG) pedigree from a village in southern India and to investigate the genetic basis of their disease. Materials and methods: Eighty-four members of a large pedigree received complete eye examinations including ...
Could distal MSH2 upstream deletions cause HNPCC?
... of morphogenetic ligands while migrating to the villus, before being shed in the lumen. Right: a schematic description of the differentiation pathways in the gut epithelium. BMP, bone morphogeneic protein; TGFβ, transforming growth factor β. ...
... of morphogenetic ligands while migrating to the villus, before being shed in the lumen. Right: a schematic description of the differentiation pathways in the gut epithelium. BMP, bone morphogeneic protein; TGFβ, transforming growth factor β. ...
Document
... for which the number of analysed sequences is very high. Is there a similar variability in wild sheep and goats? Available data are too limited and not peer-reviewed to answer this conclusively. PrP analysis of Ovis canadensis (Bighorn sheep) (accession No. DQ648468 to DQ648477) suggests significant ...
... for which the number of analysed sequences is very high. Is there a similar variability in wild sheep and goats? Available data are too limited and not peer-reviewed to answer this conclusively. PrP analysis of Ovis canadensis (Bighorn sheep) (accession No. DQ648468 to DQ648477) suggests significant ...
The development and evolutionary origin of barbels in
... members of the Bone morphogenetic protein (Bmp), Distal-less (Dlx), Fibroblast growth factor (Fgf), Hedgehog (Hh), Tumor necrosis factor (Tnf), and Tnf receptor families. Other genes with roles in appendage development were absent from barbels, however, including members of the Dachshund (Dach) and ...
... members of the Bone morphogenetic protein (Bmp), Distal-less (Dlx), Fibroblast growth factor (Fgf), Hedgehog (Hh), Tumor necrosis factor (Tnf), and Tnf receptor families. Other genes with roles in appendage development were absent from barbels, however, including members of the Dachshund (Dach) and ...
Leptin in Obesity: An Example of altered Homeostasis
... selective. They were not for all the central as ...
... selective. They were not for all the central as ...
Concentrations of the atherogenic Lp(a) are elevated in FH
... Lipoprotein(a) (Lp(a)) is a complex in human plasma assembled from lowdensity lipoprotein (LDL) and apolipoprotein(a) (apo(a)). High plasma concentrations of Lp(a) are a risk factor for coronary heart disease (CHD) in particular in patients with concomitant elevation of LDL. We have analysed for ele ...
... Lipoprotein(a) (Lp(a)) is a complex in human plasma assembled from lowdensity lipoprotein (LDL) and apolipoprotein(a) (apo(a)). High plasma concentrations of Lp(a) are a risk factor for coronary heart disease (CHD) in particular in patients with concomitant elevation of LDL. We have analysed for ele ...
Gene expression analysis
... Why find genes that behave differently in two classes (e.g. normal and tumor)? Better understanding of the genetic circumstances that cause the difference (disease) hopefully leads to better therapy. Detection of marker-genes enables the early recognition of diseases as well as the recognition of su ...
... Why find genes that behave differently in two classes (e.g. normal and tumor)? Better understanding of the genetic circumstances that cause the difference (disease) hopefully leads to better therapy. Detection of marker-genes enables the early recognition of diseases as well as the recognition of su ...
protein 2 gene: study of a cohort of Israeli patients - MRC
... 453CRT (pD151E), resulting in a change of a conserved residue at the methyl-binding domain, and a rare GT deletion of intron 1 donor splice site are reported. It is shown that various MECP2 mutations had distinct effects on MECP2 expression levels in peripheral blood. The most significant (p,0.001) ...
... 453CRT (pD151E), resulting in a change of a conserved residue at the methyl-binding domain, and a rare GT deletion of intron 1 donor splice site are reported. It is shown that various MECP2 mutations had distinct effects on MECP2 expression levels in peripheral blood. The most significant (p,0.001) ...
Mouse Lefty2 and Zebrafish Antivin Are Feedback
... The murine “lefty” locus is composed of two highly conserved genes, lefty1 and lefty2, which are tightly linked on chromosome 1 (Meno et al., 1997). To examine the role of lefty2 in gastrulation and L–R asymmetry, we generated mutant mice deficient in lefty2. To inactivate lefty2, we constructed a t ...
... The murine “lefty” locus is composed of two highly conserved genes, lefty1 and lefty2, which are tightly linked on chromosome 1 (Meno et al., 1997). To examine the role of lefty2 in gastrulation and L–R asymmetry, we generated mutant mice deficient in lefty2. To inactivate lefty2, we constructed a t ...
SelectedJournalAsthm..
... Colilla S, Nicolae D, Pluzhnikov A, et al. Evidence for gene-environment interactions in a linkage study of asthma and smoking exposure. J Allergy Clin Immunol 2003;111:840-6. David GL, Romieu I, Sienra-Monge JJ, et al. NAD(P)H: Quinone Oxidoreductase and glutathione s-transferase M1 polymorphisms a ...
... Colilla S, Nicolae D, Pluzhnikov A, et al. Evidence for gene-environment interactions in a linkage study of asthma and smoking exposure. J Allergy Clin Immunol 2003;111:840-6. David GL, Romieu I, Sienra-Monge JJ, et al. NAD(P)H: Quinone Oxidoreductase and glutathione s-transferase M1 polymorphisms a ...
Charles K. Wairuri , Jacquie E. van der Waals
... pilin, with adjacent glutamate and tyrosine residues in its centre (Kachlany et al. 2001; Planet ...
... pilin, with adjacent glutamate and tyrosine residues in its centre (Kachlany et al. 2001; Planet ...