Endogenous Cerberus activity is required for anterior head
... injection of the CerMo does not cause visible head defects in the Xenopus embryo. In contrast, targeted increase of BMP, Nodal or Wnt activity in the ADE resulted specifically in the loss of head, but not trunk-tail structures. These factors synergistically inhibited head structures when simultaneou ...
... injection of the CerMo does not cause visible head defects in the Xenopus embryo. In contrast, targeted increase of BMP, Nodal or Wnt activity in the ADE resulted specifically in the loss of head, but not trunk-tail structures. These factors synergistically inhibited head structures when simultaneou ...
Consensus Statement on Factor V Leiden Mutation Testing
... readily available. At present, only the prothrombin 20210A variant fits these criteria. It is present in 1-2% of the general population, its involvement in venous thromboembolism is well-established, and the DNA test is as simple as that for factor V Leiden (with which it can even be multiplexed). P ...
... readily available. At present, only the prothrombin 20210A variant fits these criteria. It is present in 1-2% of the general population, its involvement in venous thromboembolism is well-established, and the DNA test is as simple as that for factor V Leiden (with which it can even be multiplexed). P ...
19. - 21. März 2014 in Essen - Deutsche Gesellschaft für
... Beisitzer: Univ. Prof. DDr. J. Zschocke, Innsbruck Assoziiert: Univ. Prof. Dr. B. Streubel, Wien Bundesfachgruppenobmann: Univ. Doz. Dr. H.-Ch. Duba, Linz ...
... Beisitzer: Univ. Prof. DDr. J. Zschocke, Innsbruck Assoziiert: Univ. Prof. Dr. B. Streubel, Wien Bundesfachgruppenobmann: Univ. Doz. Dr. H.-Ch. Duba, Linz ...
Abstracts - Parthenon Management Group
... particular genes, such as BDNF in a stress model of depression, and RELN in schizophrenia. There is some evidence in both of these cases that medications that can reverse the epigenetic changes observed. Other intriguing findings have been those of stress-induced epigenetic modifications of genes in ...
... particular genes, such as BDNF in a stress model of depression, and RELN in schizophrenia. There is some evidence in both of these cases that medications that can reverse the epigenetic changes observed. Other intriguing findings have been those of stress-induced epigenetic modifications of genes in ...
Pleiotropic effects of the mouse lethal yellow (Ay) mutation
... from protein-coding sequences, and produce fragments of 342 bp or 259 bp depending on the presence or absence, respectively, of an alternatively spliced 83 bp exon (see Figs 4, 5). The identity of the products was confirmed both by direct sequencing and by Southern hybridization with the Merc cDNA p ...
... from protein-coding sequences, and produce fragments of 342 bp or 259 bp depending on the presence or absence, respectively, of an alternatively spliced 83 bp exon (see Figs 4, 5). The identity of the products was confirmed both by direct sequencing and by Southern hybridization with the Merc cDNA p ...
PDF
... Martinez et al., 2005). Another contributing factor to the cataract formation in Foxe3 mutants might be the altered expression of ␣A-crystallin. In the wild-type lens, lens fiber cells express high levels of crystallins, which can represent more than 90% of the total protein in the cell. ␣A-crystall ...
... Martinez et al., 2005). Another contributing factor to the cataract formation in Foxe3 mutants might be the altered expression of ␣A-crystallin. In the wild-type lens, lens fiber cells express high levels of crystallins, which can represent more than 90% of the total protein in the cell. ␣A-crystall ...
Gene Section ATF4 (activating transcription factor 4 (tax responsive enhancer element B67)) -
... assuring that osteoblasts fulfill their function. Rsk2deficient mice display decreased bone mass due to impaired bone formation. ATF4 is more strongly phosphorylated by Rsk2 than any other proposed substrate. ATF4-deficient mice have revealed that this transcription factor plays several crucial role ...
... assuring that osteoblasts fulfill their function. Rsk2deficient mice display decreased bone mass due to impaired bone formation. ATF4 is more strongly phosphorylated by Rsk2 than any other proposed substrate. ATF4-deficient mice have revealed that this transcription factor plays several crucial role ...
Bacterial diterpene synthases: new
... epoxide ring. In both cases, the resulting carbocation undergoes a cascade of cyclization, the fate of which is determined by a combination of steric and electrostatic forces within the active site cavity. The cyclization cascade is ultimately terminated by abstraction of a proton or electrophilic a ...
... epoxide ring. In both cases, the resulting carbocation undergoes a cascade of cyclization, the fate of which is determined by a combination of steric and electrostatic forces within the active site cavity. The cyclization cascade is ultimately terminated by abstraction of a proton or electrophilic a ...
Are Restriction Enzymes Recognition Sites Underrepresented in the
... enzymes, their properties and annotation was created. The result from RRSR was statistically tested in R using Chi square goodness of fit test and the results showed that many restriction enzymes had their recognition sites underrepresented in their host genome. Adaptive bacterial ada regulon system ...
... enzymes, their properties and annotation was created. The result from RRSR was statistically tested in R using Chi square goodness of fit test and the results showed that many restriction enzymes had their recognition sites underrepresented in their host genome. Adaptive bacterial ada regulon system ...
Chromosomal translocations deregulated BCL6
... 1995). Its features and pattern of expression suggest that BCL6 may function as a DNA-binding transcription factor involved in the control of B cell differentiation and lymphoid organ development. Chromosomal translocations affecting band 3q27 represent reciprocal recombinations between this genomic ...
... 1995). Its features and pattern of expression suggest that BCL6 may function as a DNA-binding transcription factor involved in the control of B cell differentiation and lymphoid organ development. Chromosomal translocations affecting band 3q27 represent reciprocal recombinations between this genomic ...
SVPaper050711
... 349 bp, with modes at 100 bp and 6,400 bp, LINE insertions comprising the majority of the larger insertions (Fig. 3a). Outgroup analysis showed that the transposon-derived SVs arose almost exclusively from ancestral insertions events (98.8%). Target site duplications (12-16 bp) surrounds the breakpo ...
... 349 bp, with modes at 100 bp and 6,400 bp, LINE insertions comprising the majority of the larger insertions (Fig. 3a). Outgroup analysis showed that the transposon-derived SVs arose almost exclusively from ancestral insertions events (98.8%). Target site duplications (12-16 bp) surrounds the breakpo ...
MSc Seminar: Donald Dunbar
... Non specific binding of labelled target Need to exclude this background Several methods exist ...
... Non specific binding of labelled target Need to exclude this background Several methods exist ...
Interleukin?1 gene cluster variants with innate cytokine production
... IL-10 levels, occurred among subjects with familial OA at multiple sites, as compared with controls. The innate ex vivo production of TNF␣, which was not associated with the onset of OA, was the only cytokine that predisposed to knee OA progression (15). In recent years the concept that inflammation ...
... IL-10 levels, occurred among subjects with familial OA at multiple sites, as compared with controls. The innate ex vivo production of TNF␣, which was not associated with the onset of OA, was the only cytokine that predisposed to knee OA progression (15). In recent years the concept that inflammation ...
Drosophila WntD is a target and an inhibitor of the Dorsal/Twist/Snail
... Fig. 2. Genetic regulation of wntD expression. (A-F) The expression of wntD and sim in wild-type (WT) embryos. Both genes have lateral stripes of expression. Only wntD shows a lower level of expression in ventral cells, and only sim has a characteristic stripe in the posterior region (arrows in C an ...
... Fig. 2. Genetic regulation of wntD expression. (A-F) The expression of wntD and sim in wild-type (WT) embryos. Both genes have lateral stripes of expression. Only wntD shows a lower level of expression in ventral cells, and only sim has a characteristic stripe in the posterior region (arrows in C an ...
Building Individualized Medicine: Prevention of Adverse Reactions
... are determined by interplay of approximately 30 genes, and genetic analysis of this pharmacological pathway is still in progress (Wadelius and Pirmohamed, 2006). Warfarin is the most widely used oral anticoagulant in the world for patients with venous thrombosis, pulmonary embolism, chronic atrial f ...
... are determined by interplay of approximately 30 genes, and genetic analysis of this pharmacological pathway is still in progress (Wadelius and Pirmohamed, 2006). Warfarin is the most widely used oral anticoagulant in the world for patients with venous thrombosis, pulmonary embolism, chronic atrial f ...
Transvection Is Common Throughout the Drosophila
... Our analysis of transvection focuses on the ventral nerve cord (VNC) of the Drosophila larva, which contains a segmentally repeating, stereotyped array of stem cells (neuroblasts). Each neuroblast generates a stereotyped lineage that is easily identifiable during late larval life based on the charact ...
... Our analysis of transvection focuses on the ventral nerve cord (VNC) of the Drosophila larva, which contains a segmentally repeating, stereotyped array of stem cells (neuroblasts). Each neuroblast generates a stereotyped lineage that is easily identifiable during late larval life based on the charact ...
Transcriptional Attenuation
... DNA segment that encodes the 1:2 RNA hairpin (Fig. 2). RNA polymerase is released from the pause site when the ribosome approaches on the nascent transcript. Once RNA polymerase leaves the pause site, the rate at which th ribosome synthesizes the remainder of the leader peptide and releases the mRNA ...
... DNA segment that encodes the 1:2 RNA hairpin (Fig. 2). RNA polymerase is released from the pause site when the ribosome approaches on the nascent transcript. Once RNA polymerase leaves the pause site, the rate at which th ribosome synthesizes the remainder of the leader peptide and releases the mRNA ...
Universal chloroplast integration and expression vectors
... The invention provides universal chloroplast integration and expression vectors which are competent to stably transform and integrate genes of interest into chloroplast genome of multiple species of plants. Transformed plants and their progeny are provided. Monocotyledonous and dicotyledonous plants ...
... The invention provides universal chloroplast integration and expression vectors which are competent to stably transform and integrate genes of interest into chloroplast genome of multiple species of plants. Transformed plants and their progeny are provided. Monocotyledonous and dicotyledonous plants ...
From DNA to diversity: molecular genetics and the evolution of
... biology, ultimately reduced to elegant genetic switches that determined the on/off state of groups of genes. This success laid the foundation for understanding the regulation of genes in different cell types of multicellular organisms and, in turn, the regulation of genes in space and over time duri ...
... biology, ultimately reduced to elegant genetic switches that determined the on/off state of groups of genes. This success laid the foundation for understanding the regulation of genes in different cell types of multicellular organisms and, in turn, the regulation of genes in space and over time duri ...
000927 - JHBS Revista Cientifica 3ª edicao
... crucial for the treatment of affected patients. However, Listeria is seldom suspected as the causative agent of endocarditis, and patient treatment is typically tailored for bacteria that are more frequently involved in endocarditis such as Staphylococcus aureus, Streptococcus viridans, Enterococcus ...
... crucial for the treatment of affected patients. However, Listeria is seldom suspected as the causative agent of endocarditis, and patient treatment is typically tailored for bacteria that are more frequently involved in endocarditis such as Staphylococcus aureus, Streptococcus viridans, Enterococcus ...
An AT-hook gene is required for palea formation and floral organ
... other grasses, class A genes in rice remain difficult to determine. Similar to rice, the maize outer whorl organ identity remains elusive that molecular dissection of regulatory pathways has just started (Thompson et al., 2009; Whipple et al., 2010). In order to understand the molecular regulation of ...
... other grasses, class A genes in rice remain difficult to determine. Similar to rice, the maize outer whorl organ identity remains elusive that molecular dissection of regulatory pathways has just started (Thompson et al., 2009; Whipple et al., 2010). In order to understand the molecular regulation of ...
Distalless and dachshund pattern both plesiomorphic
... leg pairs). In contrast to these multiple studies of the role of Dll, no functional data are available for dac, hth, or exd in any chelicerate. The most recent addition to the suite of chelicerate study organisms is the harvestman Phalangium opilio, for which we previously profiled the expression dom ...
... leg pairs). In contrast to these multiple studies of the role of Dll, no functional data are available for dac, hth, or exd in any chelicerate. The most recent addition to the suite of chelicerate study organisms is the harvestman Phalangium opilio, for which we previously profiled the expression dom ...
multicopy gene family evolution on primate y chromosomes
... Contrary to previous theories, the Y chromosome is an important determinant of male phenotype [15–17]. The Y chromosome has been found to be associated with male fertility in humans [18] and even less obvious traits like lifespan [19] and locomotive activity [20] in Drosophila species. Therefore, an ...
... Contrary to previous theories, the Y chromosome is an important determinant of male phenotype [15–17]. The Y chromosome has been found to be associated with male fertility in humans [18] and even less obvious traits like lifespan [19] and locomotive activity [20] in Drosophila species. Therefore, an ...