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... Etymology: New Latin, from Greek, act of stopping, from ephistanai to stop, from epi- + histanai to cause to stand -- more at STAND : suppression of the effect of a gene by a nonallelic gene - ep·i·stat·ic /"e-p&-'sta-tik/ adjective Merriam-Webster online: www.m-w.com ...
... Etymology: New Latin, from Greek, act of stopping, from ephistanai to stop, from epi- + histanai to cause to stand -- more at STAND : suppression of the effect of a gene by a nonallelic gene - ep·i·stat·ic /"e-p&-'sta-tik/ adjective Merriam-Webster online: www.m-w.com ...
Temperature-dependent expression of virulence genes in fish
... 2012; Han et al., 2013; Steinmann and Dersch, 2013; GrossoBecerra et al., 2014; Weber et al., 2014). They are sequences able to form intramolecular stem-loop structures affecting the ribosomal binding site (RBS) and the translation initiation codon. In that way, at low temperature, the mRNA conformat ...
... 2012; Han et al., 2013; Steinmann and Dersch, 2013; GrossoBecerra et al., 2014; Weber et al., 2014). They are sequences able to form intramolecular stem-loop structures affecting the ribosomal binding site (RBS) and the translation initiation codon. In that way, at low temperature, the mRNA conformat ...
Evolutionary dynamics of RNA-like replicator systems
... replicator network known as a hypercycle and its limitation, namely, the problem of parasites. We then show how this problem can be solved by the consideration of spatial self-organization and discrete populations. We next introduce a simpler replicator network (one-replicase one-parasite system) an ...
... replicator network known as a hypercycle and its limitation, namely, the problem of parasites. We then show how this problem can be solved by the consideration of spatial self-organization and discrete populations. We next introduce a simpler replicator network (one-replicase one-parasite system) an ...
Identification of Genes Needed for Regeneration, Stem Cell
... including humans, but poorly understood mechanistically (Weissman, 2000). Thus, planarians provide arenas for mechanistic investigation of in vivo stem cell regulation that are likely to inform the functioning of stem cells in all animals. How can the function of genes regulating planarian biology b ...
... including humans, but poorly understood mechanistically (Weissman, 2000). Thus, planarians provide arenas for mechanistic investigation of in vivo stem cell regulation that are likely to inform the functioning of stem cells in all animals. How can the function of genes regulating planarian biology b ...
Misregulation of pre-mRNA splicing that causes human diseases
... About one third of all human genes are subject to alternative splicing. The molecular mechanisms that regulate alternative splice site usage are beginning to emerge and show that transcription and pre-mRNA processing are integrated processes that can be modified by cellular signals. Several diseases ...
... About one third of all human genes are subject to alternative splicing. The molecular mechanisms that regulate alternative splice site usage are beginning to emerge and show that transcription and pre-mRNA processing are integrated processes that can be modified by cellular signals. Several diseases ...
Tissue-specific expression of AUX1 in maize roots
... The expression pattern of ZmAUX1 correlates with the region where saturable auxin uptake was observed, implicating the existence of an influx carrier (Martin and Pilet 1986). In this region, the proximal auxin transport, from the root base to the root tip through the central cylinder (Mitchell and D ...
... The expression pattern of ZmAUX1 correlates with the region where saturable auxin uptake was observed, implicating the existence of an influx carrier (Martin and Pilet 1986). In this region, the proximal auxin transport, from the root base to the root tip through the central cylinder (Mitchell and D ...
Discovering the Distribution of Palindromic Sequences in the
... complement of the former half, differ from lexical palindromes which read exactly the same forwards and backwards. Palindromic sequences have a tendency of creating hairpin loops which are secondary RNA structures. These hairpin loops (also known as stem-loops) have many purposes which include prote ...
... complement of the former half, differ from lexical palindromes which read exactly the same forwards and backwards. Palindromic sequences have a tendency of creating hairpin loops which are secondary RNA structures. These hairpin loops (also known as stem-loops) have many purposes which include prote ...
An accessible database for mouse and human whole transcriptome
... saves time and work and reduces technical bias. Primer design for qPCR is a relatively simple but repetitive time-consuming task. The first step is to choose a target sequence, for which one then has to define constraints about the primers’ product and reaction conditions. Then, available software ( ...
... saves time and work and reduces technical bias. Primer design for qPCR is a relatively simple but repetitive time-consuming task. The first step is to choose a target sequence, for which one then has to define constraints about the primers’ product and reaction conditions. Then, available software ( ...
Ubiquitin-Like Protein 5 Positively Regulates Chaperone Gene
... GATC-39) and F46F11.2AS (59-GAAATGAATTCTGATGAAT CATTGG-39) and the C. briggsae cDNA was amplified using the same UBL-5.brig.1S and UBL-5.brig.2AS primers described above. The inserts were ligated into the pPD129.36 plasmid. The screen for genes whose inactivation by RNAi interferes with hsp-60Tgfp e ...
... GATC-39) and F46F11.2AS (59-GAAATGAATTCTGATGAAT CATTGG-39) and the C. briggsae cDNA was amplified using the same UBL-5.brig.1S and UBL-5.brig.2AS primers described above. The inserts were ligated into the pPD129.36 plasmid. The screen for genes whose inactivation by RNAi interferes with hsp-60Tgfp e ...
Jigsaw handout - the Biology Scholars Program Wiki
... Summary of background information given in a reading and reinforced in a short lecture: The lac operon contains genes required for the uptake and utilization of the sugar, lactose. When lactose is not present, the proteins encoded by the genes are not needed and the operon is not transcribed. When ...
... Summary of background information given in a reading and reinforced in a short lecture: The lac operon contains genes required for the uptake and utilization of the sugar, lactose. When lactose is not present, the proteins encoded by the genes are not needed and the operon is not transcribed. When ...
RT2 Profiler™ PCR Arrays: Pathway
... the optimized formulation also allows you to directly use the RNA preparation for reverse transcription and finally real-time PCR without affecting reaction performance. By eliminating genomic DNA contamination, real-time PCR signal intensities accurately reflect the relative level of gene-specific mRN ...
... the optimized formulation also allows you to directly use the RNA preparation for reverse transcription and finally real-time PCR without affecting reaction performance. By eliminating genomic DNA contamination, real-time PCR signal intensities accurately reflect the relative level of gene-specific mRN ...
Counting Small RNA in Pathogenic Bacteria
... key insights into how messenger RNA (mRNA) are produced,1 the regulatory role of long noncoding RNA,2 and determination of cell fate by spatial patterning. One key method used to obtain single cell expression data is singlemolecule fluorescence hybridization (smFISH), a technique first introduced for ...
... key insights into how messenger RNA (mRNA) are produced,1 the regulatory role of long noncoding RNA,2 and determination of cell fate by spatial patterning. One key method used to obtain single cell expression data is singlemolecule fluorescence hybridization (smFISH), a technique first introduced for ...
The relative rates of synthesis of DNA, sRNA and rRNA in the
... precursor demands a knowledge of the specific activity of the immediate precursor pool. We have not been able to estimate this in parts of embryos because it would be hard to obtain sufficient material, and because the specific activity of the pool changes rapidly during short periods of labelling. ...
... precursor demands a knowledge of the specific activity of the immediate precursor pool. We have not been able to estimate this in parts of embryos because it would be hard to obtain sufficient material, and because the specific activity of the pool changes rapidly during short periods of labelling. ...
Regulation of Gene Expression
... transcription of specific genes in eukaryotes also exist. For example, when a repressor has attached to the silencer region near the enhancers, activators can be prevented from binding to the enhancers, and transcription is • repressed. ...
... transcription of specific genes in eukaryotes also exist. For example, when a repressor has attached to the silencer region near the enhancers, activators can be prevented from binding to the enhancers, and transcription is • repressed. ...
The Comparison of Transcriptomes Undergoing Waterlogging at the
... ZS9. However, in other categories, expression of most of these down-regulated genes was more greatly decreased in ZS9 compared with GH01. For example, the gene encoding “phosphoenolpyruvate carboxylase” (Bra024730) was decreased by 4.65-fold change in ZS9 compared with a 4.04-fold change in GH01. Th ...
... ZS9. However, in other categories, expression of most of these down-regulated genes was more greatly decreased in ZS9 compared with GH01. For example, the gene encoding “phosphoenolpyruvate carboxylase” (Bra024730) was decreased by 4.65-fold change in ZS9 compared with a 4.04-fold change in GH01. Th ...
Quantitative genetics of gene expression during fruit fly - EMBL-EBI
... through which differences between genomes result in differences between whole organisms remain poorly understood. To bridge this gap between genotype and phenotype, we need to understand the consequences of genetic variation at the cellular level. A major factor in this is gene regulation, in which ...
... through which differences between genomes result in differences between whole organisms remain poorly understood. To bridge this gap between genotype and phenotype, we need to understand the consequences of genetic variation at the cellular level. A major factor in this is gene regulation, in which ...
- Philsci-Archive
... on finding criteria that distinguish causal from non-causal relationships. There is, however, another important project, also belonging to the philosophy of causation that has received less attention, at least among philosophers. This is the project of elucidating and understanding the basis for var ...
... on finding criteria that distinguish causal from non-causal relationships. There is, however, another important project, also belonging to the philosophy of causation that has received less attention, at least among philosophers. This is the project of elucidating and understanding the basis for var ...
tRNA-derived short RNAs bind to Saccharomyces cerevisiae
... amounts of tRNA fragments pool, we have shown the differential processing of almost all individual tRNA isoforms. The mode of gene expression regulation by tRNA cleavage is not well understood yet, but similarly to its biogenesis it seems to differ between higher eukaryotes and other organisms. One ...
... amounts of tRNA fragments pool, we have shown the differential processing of almost all individual tRNA isoforms. The mode of gene expression regulation by tRNA cleavage is not well understood yet, but similarly to its biogenesis it seems to differ between higher eukaryotes and other organisms. One ...
Review over DNA, RNA, proteins, viruses, bacteria, DNA technology
... Essential knowledge 3.C.2: Biological systems have multiple processes that increase genetic variation. c. Sexual reproduction in eukaryotes involving gamete formation, including crossing-over during meiosis and the random assortment of chromosomes during meiosis, and fertilization serve to increase ...
... Essential knowledge 3.C.2: Biological systems have multiple processes that increase genetic variation. c. Sexual reproduction in eukaryotes involving gamete formation, including crossing-over during meiosis and the random assortment of chromosomes during meiosis, and fertilization serve to increase ...
Morphology of nuclear transcription | SpringerLink
... The rRNA is transcribed from rDNA, which is present in a unique conformation in the genome. Individual genes are arranged in a repetitive head-to-tail orientation. The transcribed genes (transcription units; TU) are separated by intergenic spacer sequences (IGS). Several tens of such repeats form a ...
... The rRNA is transcribed from rDNA, which is present in a unique conformation in the genome. Individual genes are arranged in a repetitive head-to-tail orientation. The transcribed genes (transcription units; TU) are separated by intergenic spacer sequences (IGS). Several tens of such repeats form a ...
INTRODUCTION - Mount Holyoke College
... do not extend properly, resulting in a crooked leg phenotype. This leg defect is associated with inappropriate orientation of leg imaginal discs and the presence of peripodial epithelium that appears to impede leg disc eversion and leg extension, suggesting that how plays a role in interactions betw ...
... do not extend properly, resulting in a crooked leg phenotype. This leg defect is associated with inappropriate orientation of leg imaginal discs and the presence of peripodial epithelium that appears to impede leg disc eversion and leg extension, suggesting that how plays a role in interactions betw ...
RT2 Profiler PCR Arrays: Pathway-focused gene
... Abstract: This paper evaluates the performance of the newest technique for monitoring the expression of a panel of pathway- or disease-specific genes: the RT2 Profiler PCR Array System. The RT2 Profiler PCR Array System combines the quantitative performance of SYBR® Green real-time PCR with the mult ...
... Abstract: This paper evaluates the performance of the newest technique for monitoring the expression of a panel of pathway- or disease-specific genes: the RT2 Profiler PCR Array System. The RT2 Profiler PCR Array System combines the quantitative performance of SYBR® Green real-time PCR with the mult ...
Identification of functional domains in Arabidopsis thaliana mRNA
... (AtDcp2) was characterized by bioinformatics analysis and by biochemical studies of the enzyme and mutants produced by recombinant expression. Three functionally significant regions were detected: (i) a highly disordered C-terminal region with a putative PSD-95, Discs-large, ZO-1 (PDZ) domain-bindin ...
... (AtDcp2) was characterized by bioinformatics analysis and by biochemical studies of the enzyme and mutants produced by recombinant expression. Three functionally significant regions were detected: (i) a highly disordered C-terminal region with a putative PSD-95, Discs-large, ZO-1 (PDZ) domain-bindin ...
Differential Gene Expression in the Siphonophore
... workflows: SOLiD SAGE (Life Technologies), Illumina mRNASeq, and Helicos Digital Gene Expression (DGE). These workflows differ in sample preparation protocols (Figure S1), sequencing platform, and read mapping. All these differences have the potential to impact each workflow’s ability to measure dif ...
... workflows: SOLiD SAGE (Life Technologies), Illumina mRNASeq, and Helicos Digital Gene Expression (DGE). These workflows differ in sample preparation protocols (Figure S1), sequencing platform, and read mapping. All these differences have the potential to impact each workflow’s ability to measure dif ...