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lecture1
lecture1

... From pre-mRNA to mRNA: Splicing • In some species (e.g. eukaryotes), not every part of a gene is coding – Functional exons interrupted by non-translated introns – During pre-mRNA maturation, introns are spliced out – In humans, primary transcript can be 106 bp long – Alternative splicing can yield ...
DNA Practice problems
DNA Practice problems

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Fill-in-Notes - Pearland ISD
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transformation mean? transcription and translation
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... Be able to describe the process of DNA replication (DNA making exact copy of itself). Be able to put the following in order of size (DNA, cell, nucleotide, nucleus, chromosome). RNA (like DNA) is also composed of nucleotides, but the RNA strand differs from DNA: Single-strand (not double-stranded) R ...
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Albert Libchaber Detlev W. Bronk Professor The Rockefeller
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... - In the RNA world of the early soup we are studying how a genetic code could originate, building an RNA ribozyme that can charge an amino acid without enzymes, a primitive tRNA. We also show that the initial code could have started with four amino acids only: valine (GUC), alanine (GCC), glycine (G ...
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... subunits and functioning as the site of protein synthesis in the cytoplasm. 22. Describe the process of translation including initiation, elongation, and termination Know from AP Cliff Notes 27. Explain how eukaryotic mRNA is processed before it leaves the nucleus. RNA transcripts in eukaryotes are ...
DNA, Genes and Chromosomes
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... • The information in DNA is stored as a code made up of four chemical bases: adenine (A), guanine (G), cytosine (C), and thymine (T). ...
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Primary transcript



A primary transcript is the single-stranded ribonucleic acid (RNA) product synthesized by transcription of DNA, and processed to yield various mature RNA products such as mRNAs, tRNAs, and rRNAs. The primary transcripts designated to be mRNAs are modified in preparation for translation. For example, a precursor messenger RNA (pre-mRNA) is a type of primary transcript that becomes a messenger RNA (mRNA) after processing.There are several steps contributing to the production of primary transcripts. All these steps involve a series of interactions to initiate and complete the transcription of DNA in the nucleus of eukaryotes. Certain factors play key roles in the activation and inhibition of transcription, where they regulate primary transcript production. Transcription produces primary transcripts that are further modified by several processes. These processes include the 5' cap, 3'-polyadenylation, and alternative splicing. In particular, alternative splicing directly contributes to the diversity of mRNA found in cells. The modifications of primary transcripts have been further studied in research seeking greater knowledge of the role and significance of these transcripts. Experimental studies based on molecular changes to primary transcripts the processes before and after transcription have led to greater understanding of diseases involving primary transcripts.
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