• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Chromatin DNA Methylayion
Chromatin DNA Methylayion

... Increased MBD2/demethylase is responsible for global hypomethylation and maintaining tumor invasion genes hypomethylated and active ...
Review Article
Review Article

... infection; then they will need to obtain nutrients and to multiply while at the same time evading the host defence mechanisms. In some instances, they may need to invade host cells for survival or further dissemination within the host (Finlay & Falkow, 1989). The recognition that bacterial pathogeni ...
The Development of a Genetic Marker for Resistance to Fescue
The Development of a Genetic Marker for Resistance to Fescue

... fragments following a sequence-specific digestion with the Tfi I enzyme (New England Biolabs, Ipswich, MA). The enzyme cuts the DNA sequence at the specific polymorphism if it contains an A; if the sequence contains a G it would not be cut. A gel was then run to allow the DNA fragments to separate s ...
MOLECULAR TECHNIQUES IN LABORATORY DIAGNOSIS
MOLECULAR TECHNIQUES IN LABORATORY DIAGNOSIS

... In the field of infectious diseases the technique has been shown to be a valuable method for identification of: • viruses • bacteria • fungi • parasites • All Dr.Sarookhani ...
iron-regulatory protein 1
iron-regulatory protein 1

... been previously described by Moeder et al. [20] and was named KO-661 [20]. Lines homozygous for the disruption were isolated, and used for further studies. When the mutants were grown in a greenhouse, or in hydroponic cultures under controlled conditions, they displayed no macroscopic phenotype. Fur ...
1 Defining the epigenetic mechanism of asymmetric cell division of
1 Defining the epigenetic mechanism of asymmetric cell division of

... to the H2 box (EGEL 2005; KLAR 2007). The three cassettes reside in direct orientation and encompass a 30-kb region in the middle of chromosome 2, which also contains genes unrelated to the mating process. Thus far the S. pombe mating is the only system where double helical structure of DNA has been ...
Unusual mutations in high functioning fragile X males
Unusual mutations in high functioning fragile X males

... repeat expansions to CGG copy numbers between 45 and 200. They are usually not associated with methylation. Premutations are carried by transmitting males and by some of the transmitting females. Carriers of premutations are generally unaffected and show normal expression of the premutated gene both ...
Multistep process of FUS aggregation in the cell cytoplasm involves
Multistep process of FUS aggregation in the cell cytoplasm involves

... diffuse regardless of expression levels (Fig. 3B and C). Therefore, even formation of FGs, the process initiating FUS aggregation in the cytoplasm, requires both the prion-like activity of its N-terminal domains and binding to a specific pool of RNAs. FGs are a novel type of RNA granule In cells exp ...
Bridging structural biology and genomics: assessing protein
Bridging structural biology and genomics: assessing protein

... interactions. Yet it is critical, because in yeast, for example, there are a possible 18 million protein interactions (given 6000 proteins), of which only a small fraction is relevant biologically. With so many potential interactions, even a very small false-positive rate can create a large amount o ...
CoevolPaper2 - University of Illinois Archives
CoevolPaper2 - University of Illinois Archives

... phylogeny of the insertion for the main classes of bacteria. The insertion clearly divides into two main types: a zinc binding motif (type I) containing four cysteines (this region can be identified as zinc binding from the Thermus thermophilus structures) and a non-zinc binding version (type II). Th ...
Ribosomal RNA Secondary Structure
Ribosomal RNA Secondary Structure

... pairing and nonpairing bases are 1,082 (54.4%) and 907 (45.6%)) respectively (table 1). These proportions are not significantly different [x2 = 0.03, degrees of freedom (df) = 1, P > 0.81 from the proportions predicted by the Xenopus model of secondary structure for the entire 28s gene [ 2,244 (54.6 ...
Word file (68 KB )
Word file (68 KB )

... cdk7ts1 flies are fully viable at the permissive temperature (18C) and exhibit complete lethality at the restrictive temperature (27C). Between 25C and 26C a small proportion of the cdk7ts1 flies survive. Conditions under which the mutant phenotype is partially penetrant provide a sensitive envi ...
Analysis of expressed sequence tags from the Huperzia serrata leaf
Analysis of expressed sequence tags from the Huperzia serrata leaf

... tetraketides (Morita et al. 2007, Wanibuchi et al. 2007). However, as of January 2009, there were only 10 nucleotide sequences from H . serrata available in the NCBI database. The limited information on the genetic contents of this plant triggered our efforts to construct a cDNA library from the H . ...
Genetic and Epigenetic Regulation in Age
Genetic and Epigenetic Regulation in Age

... the machinery of epigenetic regulation that is ultimately responsible for the gene expression regulation. The most common DNA methylation form is the 5¶ methylcytosine. It occurs predominantly in the symmetric CG context. Approximately 70% to 80% of CG dinucleotides of the genome are normally methyl ...
Introduction - bei DuEPublico
Introduction - bei DuEPublico

... cancer genes are often involved in pathways that regulate growth, apoptosis, angiogenesis and replication. For example, the p53 protein is a transcription factor that inhibits cell growth and stimulates cell death. The p53 pathway (Fig 1-1-b) can be disrupted by point mutation in the p53 gene, or by ...
unit-2 genetics of prokaryotes and eukaryotic
unit-2 genetics of prokaryotes and eukaryotic

... technique is called chromosome mapping. If linkage groups are already established in an organism, trisomics can be effectively used for assigning these linkage groups to specific chromosomes. Since the segregation ratio for genes located on the chromosome involved in trisomic condition differs from ...
Chemical Genetics
Chemical Genetics

... only one dose of each gene in any nucleus and any mutant characteristic will be expressed unless the genetic background contains special modifier or suppressor genes. It is therefor~ossible to recognize mutations produced by a treatment more immediately than with diploid organisms such as Drosophila ...
Myb genes enhance tobacco trichome production
Myb genes enhance tobacco trichome production

... developmental programs have been at least partly conserved over evolutionary time. At the outset of the present study we hypothesized that this conservation would be reflected by heterologous functioning of known epidermal cell shape regulators. Herein we describe an unsuccessful attempt to replace ...
Dynamics and control of DNA sequence amplification
Dynamics and control of DNA sequence amplification

... cycles of heating and cooling or temperature gradients generated by geothermal activity7 . Mutations occurring during these cycles of environmentally controlled replication may then have led to functional nucleic acids that ultimately developed the ability to self-replicate8 . Thus, unlike the Darwi ...
DNA breathing dynamics distinguish binding from nonbinding
DNA breathing dynamics distinguish binding from nonbinding

... All fragments contain the flanking sequence (CCT) on both ends to minimize end wobbling. The gel shift results are consistent between three independent experiments. The gel shift reactions are conducted at 37 C. RESULTS LMD simulations distinguish true YY1 binding from nonbinding sites in the human ...
Figure 15.6 Nonreplicative transposition allows a transposon to
Figure 15.6 Nonreplicative transposition allows a transposon to

... repeats, an internal res site, and three known genes. ...
15.13 Spm elements influence gene expression
15.13 Spm elements influence gene expression

... repeats, an internal res site, and three known genes. ...
Mechanistic Comparison of High-Fidelity and Error
Mechanistic Comparison of High-Fidelity and Error

... magnesium ion (often called the catalytic magnesium ion) is coordinated by both the 3′-OH nucleophile of the primer and the R-phosphate of the incoming dNTP (Figure 1); collectively, these two ions serve to stabilize what is presumably an electron-rich, associative transition state. Since the chemic ...
View PDF - BioEnergy Science Center
View PDF - BioEnergy Science Center

... et al., 2005). The transformation was performed in the wild type and previously reported low-lignin HCT- and COMT-antisense transgenic backgrounds (Guo et al., 2001a; Shadle et al., 2007). Lines showing the presence of the transgene in the genomic DNA were selected for further characterization, and ...
AnsteadSeniorHonorsThesis
AnsteadSeniorHonorsThesis

... of that range is entered into Flybase in order to generate the Gbrowser displaying the genes specific to that region. Each gene is then sorted through, and genes of interest are identified by their molecular function and biological process performed. Genes associated with functions such as: DNA bind ...
< 1 ... 16 17 18 19 20 21 22 23 24 ... 498 >

Primary transcript



A primary transcript is the single-stranded ribonucleic acid (RNA) product synthesized by transcription of DNA, and processed to yield various mature RNA products such as mRNAs, tRNAs, and rRNAs. The primary transcripts designated to be mRNAs are modified in preparation for translation. For example, a precursor messenger RNA (pre-mRNA) is a type of primary transcript that becomes a messenger RNA (mRNA) after processing.There are several steps contributing to the production of primary transcripts. All these steps involve a series of interactions to initiate and complete the transcription of DNA in the nucleus of eukaryotes. Certain factors play key roles in the activation and inhibition of transcription, where they regulate primary transcript production. Transcription produces primary transcripts that are further modified by several processes. These processes include the 5' cap, 3'-polyadenylation, and alternative splicing. In particular, alternative splicing directly contributes to the diversity of mRNA found in cells. The modifications of primary transcripts have been further studied in research seeking greater knowledge of the role and significance of these transcripts. Experimental studies based on molecular changes to primary transcripts the processes before and after transcription have led to greater understanding of diseases involving primary transcripts.
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report