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NutriLink, v. 3
NutriLink, v. 3

... Utilizing ATP ...
Chapter 21 Biosynthetic Pathways
Chapter 21 Biosynthetic Pathways

... pyruvate to glucose does not occur by reversing the steps of glucose to pyruvate. • There are three irreversible steps in glycolysis: ---Phosphoenolpyruvate to pyruvate + ATP. ---Fructose 6-phosphate to fructose 1,6-bisphosphate. ---Glucose to glucose 6-phosphate. • These three steps are reversed in ...
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... 6. Gastric juice has a pH of 1.5 and is produced by pumping HCl from blood plasma (pH 7.4) into the stomach. a. Calculate the free energy required to concentrate the H+ in 1 L of gastric juice at 37°C. For this problem, you can ignore the effects of the transmembrane electrical potential difference. ...
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... 9)  Explain  why  2  pyruvates  are  formed  from  one  glucose  molecule  instead  of  only  one  pyruvate.   10)  Name  the  organelle  where  aerobic  respiration  occurs?   11)  During  aerobic  respiration,  carbon  dioxide  (CO2)  i ...
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Citric acid cycle



The citric acid cycle – also known as the tricarboxylic acid (TCA) cycle or the Krebs cycle – is a series of chemical reactions used by all aerobic organisms to generate energy through the oxidation of acetate derived from carbohydrates, fats and proteins into carbon dioxide and chemical energy in the form of adenosine triphosphate (ATP). In addition, the cycle provides precursors of certain amino acids as well as the reducing agent NADH that is used in numerous other biochemical reactions. Its central importance to many biochemical pathways suggests that it was one of the earliest established components of cellular metabolism and may have originated abiogenically.The name of this metabolic pathway is derived from citric acid (a type of tricarboxylic acid) that is consumed and then regenerated by this sequence of reactions to complete the cycle. In addition, the cycle consumes acetate (in the form of acetyl-CoA) and water, reduces NAD+ to NADH, and produces carbon dioxide as a waste byproduct. The NADH generated by the TCA cycle is fed into the oxidative phosphorylation (electron transport) pathway. The net result of these two closely linked pathways is the oxidation of nutrients to produce usable chemical energy in the form of ATP.In eukaryotic cells, the citric acid cycle occurs in the matrix of the mitochondrion. In prokaryotic cells, such as bacteria which lack mitochondria, the TCA reaction sequence is performed in the cytosol with the proton gradient for ATP production being across the cell's surface (plasma membrane) rather than the inner membrane of the mitochondrion.
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