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Number and spatial distribution of nuclei in the muscle fibres of
Number and spatial distribution of nuclei in the muscle fibres of

... We present here a new technique with which to visualize nuclei in living muscle fibres in the intact animal, involving injection of labelled DNA into single cells. This approach allowed us to determine the position of all of nuclei within a sarcolemma without labelling satellite cells. In contrast t ...
PDF - BMC Biotechnology
PDF - BMC Biotechnology

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... this unexpected Th2 skewing in Lyn-/- mice. To test this possibility, mast cell deficient mice (Kitw-sh/w-sh) were crossed to Lyn-/- mice. However, the resulting mice (Kitw-sh/w-sh Lyn-/-) showed no alteration of the Th2 bias [30]. This meant that the Th2 bias was initiated by another cell type able ...
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... DNA replication is a highly controlled process that allows the duplication of the genome in a rapid and accurate manner. In eukaryotes, replication is started at multiple origins on each chromosome to allow swift replication completion of the large genomes. At an origin, two replication machineries ...
Biofilm formation by staphylococci and streptococci
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Transcriptionally repressed germ cells lack a
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Transcriptionally repressed germ cells lack a subpopulation of
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... (Seydoux et al., 1996). In this organism, several newly transcribed mRNAs have been detected in somatic blastomeres as early as the 4-cell stage, but none to date have been detected in germ-line blastomeres (Seydoux and Fire, 1994; Seydoux et al., 1996). This soma-germ line difference was shown to d ...
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... was increased to 40 ␮M, the tip-focused pattern of Ca2+ distribution dissipated completely (Fig. 2B and C). To investigate whether this decrease of the fluorescence density resulted from the decreased accumulation of Fluo-4/AM dye due to the vaculation in the tip of CdCl2 -treated hairs, we observed ...
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Mutations Defining Functional Regions of the Superantigen
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... S to humans and other species (1-4). These include a group of enterotoxins (Staphylococcal enterotoxins [SEs]I), associated with food poisoning; toxic shock syndrome toxin 1 (TSST-1), associated with toxic shock syndrome; and exfoliating toxins (ExF), associated with scalded skin syndrome. Many of t ...
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... vacuole membrane, and the remaining vesicle, known as the autophagic body, is finally released to the vacuole for its degradation (Xie and Klionsky, 2007). The evolutionary conservation of autophagy among eukaryotes indicates that structural and regulatory components of this cellular process must be ...
Xyloglucan, galactomannan, glucuronoxylan, and
Xyloglucan, galactomannan, glucuronoxylan, and

... the xyloglucan, galactomannan, glucuronoxylan, and rhamnogalacturonan I isolated from soybean (Glycine max) roots and root hair cell walls. The root hair is a plant cell that extends only at its tip. All other root cells have the ability to grow in different directions (diffuse growth). Although bot ...
BCL-6 Negatively Regulates Expression of the NF- p50 Subunit B1 p105/
BCL-6 Negatively Regulates Expression of the NF- p50 Subunit B1 p105/

... both T and B cells as well as the T cell-independent Ab response are unperturbed in these mice, the GC and Th cell defects reflect BCL-6 function at specific stages of T and B cell differentiation. On the B cell side, although it is clear that the GC phenotype in the BCL-6 KO mice is B cell autonomo ...
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Mitosis



Mitosis is a part of the cell cycle in which chromosomes in a cell nucleus are separated into two identical sets of chromosomes, each in its own nucleus. In general, mitosis (division of the nucleus) is often followed by cytokinesis, which divides the cytoplasm, organelles and cell membrane into two new cells containing roughly equal shares of these cellular components. Mitosis and cytokinesis together define the mitotic (M) phase of an animal cell cycle—the division of the mother cell into two daughter cells, genetically identical to each other and to their parent cell.The process of mitosis is divided into stages corresponding to the completion of one set of activities and the start of the next. These stages are prophase, prometaphase, metaphase, anaphase, and telophase. During mitosis, the chromosomes, which have already duplicated, condense and attach to fibers that pull one copy of each chromosome to opposite sides of the cell. The result is two genetically identical daughter nuclei. The cell may then divide by cytokinesis to produce two daughter cells. Producing three or more daughter cells instead of normal two is a mitotic error called tripolar mitosis or multipolar mitosis (direct cell triplication / multiplication). Other errors during mitosis can induce apoptosis (programmed cell death) or cause mutations. Certain types of cancer can arise from such mutations.Mitosis occurs only in eukaryotic cells and the process varies in different organisms. For example, animals undergo an ""open"" mitosis, where the nuclear envelope breaks down before the chromosomes separate, while fungi undergo a ""closed"" mitosis, where chromosomes divide within an intact cell nucleus. Furthermore, most animal cells undergo a shape change, known as mitotic cell rounding, to adopt a near spherical morphology at the start of mitosis. Prokaryotic cells, which lack a nucleus, divide by a different process called binary fission.
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