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Pre-operative HBO treatment led to enhanced expression of
Pre-operative HBO treatment led to enhanced expression of

... Keeping in mind that GM3 precursors ceramide and sphingosine accumulated in nuclei may induce the apoptosis of hepatocytes in vivo, enhanced GM3 expression around the nuclei could have important implications. Namely, if GM3 molecules are more intensively expressed, their precursors ceramide and sphi ...
Topological schemas of cognitive maps and spatial learning in the
Topological schemas of cognitive maps and spatial learning in the

Protein Synthesis within Dendrites: Glycosylation
Protein Synthesis within Dendrites: Glycosylation

... Department of Neuroscience, University of Virginia School of Medicine, Charlottesville, Virginia 22908 ...
Regulated trafficking of neurotransmitter transporters: common notes
Regulated trafficking of neurotransmitter transporters: common notes

... intact cells, but will bind to all transporters in a lysed cellular preparation. With this strategy, a change in binding to intact cells with no change in total binding implies a redistribution (for examples see Pristupa et al. 1998; Doolen and Zahniser 2001). Finally, it is possible to separate int ...
GFP is the way to glow: bioimaging of the plant endomembrane
GFP is the way to glow: bioimaging of the plant endomembrane

... with a molecular mass of approximately 27 kDa. It emits green fluorescence upon excitation with UV or blue light. As specific secretory proteins or signals can be fused to GFP, usually without altering their targeting, it is a useful alternative to conventional dyes previously used to investigate en ...
Now! - Soojeede.com
Now! - Soojeede.com

...  – Enterocytes  – Kerotinocytes in the skin cells constantly dying and being replaced ...
Molecular mechanism of protrusion formation during Listeria Keith Ireton Luciano A. Rigano
Molecular mechanism of protrusion formation during Listeria Keith Ireton Luciano A. Rigano

... e-mail: wolf-dieter.schubert@ up.ac.za ...
Role for Rab7 in maturation of late autophagic vacuoles
Role for Rab7 in maturation of late autophagic vacuoles

... induction of autophagy during amino acid starvation, or the accumulation of autophagic vacuoles in cells treated with lysosomal enzyme inhibitors. The amount of the membraneassociated, 16 kDa LC3II increased at the same rate as the volume fraction of autophagic vacuoles in HeLa cells, while the amou ...
Extracellular ATP Functions as an
Extracellular ATP Functions as an

... ATP is a vital molecule used by living organisms as a universal source of energy required to drive the cogwheels of intracellular biochemical reactions necessary for growth and development. Animal cells release ATP to the extracellular milieu, where it functions as the primary signaling cue at the e ...
INVESTIGATION OF THE EFFECTOR ROLE OF
INVESTIGATION OF THE EFFECTOR ROLE OF

... species: S. dysenteriae, S. flexneri, S. boydii and S. sonnei (also known as serogroups A through D). All species share approximately 80-85% of their genome33, and have been distinctly classified as a separate clade from Escherichia coli despite their phylogenetic closeness34. Variations in the O-an ...
NUCLEAR PROTEINS II. Similarity of Nonhistone Proteins in
NUCLEAR PROTEINS II. Similarity of Nonhistone Proteins in

... proteins in all the nuclear washes and cytosol indicates that these proteins are distributed throughout the cell; (d) a histone-binding protein (J2) analogous to the HMG1 protein of K. V. Shooter, G. H. Goodwin, and E. W. Johns (Eur J. Biochem. 4"/:263-270) is a prominent nucleoplasmic protein; (e) ...
Lessons on longevity from budding yeast
Lessons on longevity from budding yeast

... The past decade has seen fundamental advances in our understanding of the ageing process and raised optimism that interventions to slow ageing may be on the horizon. Studies of budding yeast have made immense contributions to this progress. Yeast longevity factors have now been shown to modulate age ...
The Functional Influence of Burst and Tonic Firing Mode on Synaptic
The Functional Influence of Burst and Tonic Firing Mode on Synaptic

... Figure 1. Properties of synaptic connections between PGN and thalamocortical neurons. A, Schematic diagram of the recording arrangement for recordings in B–E is shown. The PGN neuron was activated via the intracellular injection of a depolarizing current pulse while recording from a recipient thalam ...
CURRICULUM VITAE
CURRICULUM VITAE

... J.Virol.Meth. 1990,27:277. 27. Consales CA, Mendonça RZ, Lucchiari MA, Vassão RC, Pereira CA. - The macrophage action on rabies virus infection in genetically selected high and low antibody responder lines of mice. Res. Virol. 1990, 141:57. 28. Braunwald J, Nonnenmacher CA, Pereira CA, Kirn A. - Inc ...
Nucleocytoplasmic interactions in the mouse embryo
Nucleocytoplasmic interactions in the mouse embryo

... A more rigorous test of the ability of foreign nuclei to support development is their placement in enucleated cytoplasm. Although the removal of the zygote pronuclei can be accomplished via micropipette penetration of the ovum plasma membrane (Modliriski, 1975,1980; Markert & Petters, 1977; Hoppe & ...
441_2009_904_MOESM1_ESM - Springer Static Content Server
441_2009_904_MOESM1_ESM - Springer Static Content Server

... identified by moderate HCN1 and weak NOS staining). A weak HCN3 expression is also seen in cells with IF13 (dark purple arrow, identified by strong NOS and no HCN1). c-panels: The triple staining for HCN1 (green, HCN1), HCN3 (red, HCN3 Shigemoto), and vilip1 (blue, vilip1) shows the strong express ...
- Wiley Online Library
- Wiley Online Library

... Discussion This study was motivated by a theoretical analysis (11) suggesting that in neurons, motor-mediated transport of cargos in small-diameter neuronal processes would be more difficult than in the larger-diameter cell body. The ...
PDF
PDF

... Currently, several well characterized natural peptides and derivatives are known to have antimicrobial properties (Hammami et al., 2009; Pelegrini et al., 2011). Among them, Temporins are relatively small AMPs (10 to 14 amino acids) found in skin secretions of amphibians (Ghiselli et al., 2002; Mang ...
HGF and TGFβ1 differently influenced Wwox regulatory function on
HGF and TGFβ1 differently influenced Wwox regulatory function on

... from breast cancer depended on Twist and Snail, we evaluated their expression and intracellular localization in response to HGF and TGFβ1, two typical stimuli of bone microenvironment [1, 2, 4, 25]. As shown in Fig. 1a, HGF rapidly and persistently enhanced Twist-protein level in nuclear extracts of ...
MAPK Phosphatase AP2C3 Induces Ectopic Proliferation of
MAPK Phosphatase AP2C3 Induces Ectopic Proliferation of

... transcription factors that are successively ushering cells though the steps of stomata lineage: SPEECHLESS (SPCH) - initiation;, MUTE - proliferation; and FAMA - stomata differentiation [13,14,15,16]. Phosphorylation of SPCH by MPK6 was shown to control the entry into stomata lineage and to connect ...
Developing Technology-Based Biology Assessments for Cell
Developing Technology-Based Biology Assessments for Cell

... encouraged to focus on the cell as the basic unit of life. Two of the main subjects that are covered in cell biology include cellular necessities/functions (i.e., energy storage and waste removal required by all organisms) and cellular structure (i.e., the differences between organisms, such as plan ...
Novel Insights into Vacuole-mediated Control of Plant Growth and
Novel Insights into Vacuole-mediated Control of Plant Growth and

... Plant vacuoles are multifunctional organelles that play important roles in plant development and growth. Vacuoles occupy most of the plant cell volume (up to 90%) and control turgor pressure required for cell expansion (Zhang et al., 2014; Marty, 1999). In addition, they are involved in the storage ...
Death of developing neurons: New insights and implications for
Death of developing neurons: New insights and implications for

... is part of homeostasis and maintenance in most organs and tissues. The situation in the nervous system is principally different, as the vast majority of neurons undergo their last round of cell division early in development. Soon after exiting the cell cycle, neurons start elongating axons to innerv ...
Stat3/Cdc25a-dependent cell proliferation promotes embryonic axis
Stat3/Cdc25a-dependent cell proliferation promotes embryonic axis

Osmotic Water Permeability of Isolated Protoplasts. Modifications
Osmotic Water Permeability of Isolated Protoplasts. Modifications

... In this paper we describe a new method for measuring Pos on protoplasts or vacuoles, 40 to 120 mm in diameter, isolated from higher-plant cells. The accuracy of the method was examined and the permeabilities obtained were compared with those from other techniques. Measurements were performed on root ...
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Mitosis



Mitosis is a part of the cell cycle in which chromosomes in a cell nucleus are separated into two identical sets of chromosomes, each in its own nucleus. In general, mitosis (division of the nucleus) is often followed by cytokinesis, which divides the cytoplasm, organelles and cell membrane into two new cells containing roughly equal shares of these cellular components. Mitosis and cytokinesis together define the mitotic (M) phase of an animal cell cycle—the division of the mother cell into two daughter cells, genetically identical to each other and to their parent cell.The process of mitosis is divided into stages corresponding to the completion of one set of activities and the start of the next. These stages are prophase, prometaphase, metaphase, anaphase, and telophase. During mitosis, the chromosomes, which have already duplicated, condense and attach to fibers that pull one copy of each chromosome to opposite sides of the cell. The result is two genetically identical daughter nuclei. The cell may then divide by cytokinesis to produce two daughter cells. Producing three or more daughter cells instead of normal two is a mitotic error called tripolar mitosis or multipolar mitosis (direct cell triplication / multiplication). Other errors during mitosis can induce apoptosis (programmed cell death) or cause mutations. Certain types of cancer can arise from such mutations.Mitosis occurs only in eukaryotic cells and the process varies in different organisms. For example, animals undergo an ""open"" mitosis, where the nuclear envelope breaks down before the chromosomes separate, while fungi undergo a ""closed"" mitosis, where chromosomes divide within an intact cell nucleus. Furthermore, most animal cells undergo a shape change, known as mitotic cell rounding, to adopt a near spherical morphology at the start of mitosis. Prokaryotic cells, which lack a nucleus, divide by a different process called binary fission.
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