Receptor-mediated sorting of soluble vacuolar proteins: myths, facts
... in the secretory pathway and diverted towards the lytic compartment of the cell (lysosome or vacuole). In animal cells, the receptor is called the mannosyl 6-phosphate receptor (MPR) and it binds hydrolase ligands in the trans-Golgi network (TGN). These ligands are then sequestered into clathrin-coa ...
... in the secretory pathway and diverted towards the lytic compartment of the cell (lysosome or vacuole). In animal cells, the receptor is called the mannosyl 6-phosphate receptor (MPR) and it binds hydrolase ligands in the trans-Golgi network (TGN). These ligands are then sequestered into clathrin-coa ...
COMMUNICATION Two categories of mammalian galactose
... full extent of their ligand-binding selectivity is only evident when larger oligosaccharide ligands are tested. The array provides an efficient way to make such comparisons. The major outcome of these studies is the demonstration that the galactose-binding receptors can be divided into two groups ba ...
... full extent of their ligand-binding selectivity is only evident when larger oligosaccharide ligands are tested. The array provides an efficient way to make such comparisons. The major outcome of these studies is the demonstration that the galactose-binding receptors can be divided into two groups ba ...
Comparing The Effects of Small Molecules BIX
... Oct4 exogenous expression were compared for expression of pluripotency markers. Total RNA was isolated from the rims of the injected ventricle and quantitative polymerase chain reaction (PCR) was performed to evaluate the expression of endogenous Oct4, Nanog, c-Myc, klf4 and Sox2 as pluripotency mar ...
... Oct4 exogenous expression were compared for expression of pluripotency markers. Total RNA was isolated from the rims of the injected ventricle and quantitative polymerase chain reaction (PCR) was performed to evaluate the expression of endogenous Oct4, Nanog, c-Myc, klf4 and Sox2 as pluripotency mar ...
Microtubule associated protein END BINDING 1b: functional domain
... increased to an average of more than 80 g/capita/day of dietary energy, from an average of approximately 64 g/capita/day in 1981 (FAOSTAT, 2015a). Despite the increase in the daily dietary energy consumption, the Food and Agriculture Organization of the United Nations (FAOUN) (2014) estimates that b ...
... increased to an average of more than 80 g/capita/day of dietary energy, from an average of approximately 64 g/capita/day in 1981 (FAOSTAT, 2015a). Despite the increase in the daily dietary energy consumption, the Food and Agriculture Organization of the United Nations (FAOUN) (2014) estimates that b ...
Germ lineage specification from a pluripotent primitive ectoderm
... pluripotency and demonstrates that given the appropriate cues for differentiation ES cells can respond by forming any of the cell types found in the adult organism. Cell lines have been derived from human blastocysts that share many of the characteristics of mouse ES cells (Thomson, Itskovitz-Eldor ...
... pluripotency and demonstrates that given the appropriate cues for differentiation ES cells can respond by forming any of the cell types found in the adult organism. Cell lines have been derived from human blastocysts that share many of the characteristics of mouse ES cells (Thomson, Itskovitz-Eldor ...
articles
... its individual cellular events. Cadherins, which can mediate differential adhesion, are commonly viewed as a central target6–8. The picture emerging from diverse EMT-related studies suggests that precise molecular and cellular control of EMT is complex and context-dependent9. Rho GTPases belong to a ...
... its individual cellular events. Cadherins, which can mediate differential adhesion, are commonly viewed as a central target6–8. The picture emerging from diverse EMT-related studies suggests that precise molecular and cellular control of EMT is complex and context-dependent9. Rho GTPases belong to a ...
- University of East Anglia
... the contralateral, non-electroporated side (Fig. 1A, B). Measurements using ImageJ illustrate the reduced size of the dermomyotome and myotome . The size reduction was reproducible but variable, which is most likely due to variations in experimental parameters, such as for example transfection effi ...
... the contralateral, non-electroporated side (Fig. 1A, B). Measurements using ImageJ illustrate the reduced size of the dermomyotome and myotome . The size reduction was reproducible but variable, which is most likely due to variations in experimental parameters, such as for example transfection effi ...
Early development of the zebrafish pronephros and analysis of
... 4656 I. A. Drummond and others to kidneys in higher vertebrates, as evidenced by the cellular architecture of the pronephric glomerulus and in the specialized transport functions of pronephric tubular epithelial cells (Tytler, 1988). These features make the zebrafish pronephros a simple and accessi ...
... 4656 I. A. Drummond and others to kidneys in higher vertebrates, as evidenced by the cellular architecture of the pronephric glomerulus and in the specialized transport functions of pronephric tubular epithelial cells (Tytler, 1988). These features make the zebrafish pronephros a simple and accessi ...
Molecular Plant-Microbe Interaction
... Trotta et al. (1996) demonstrated that although improved phosphate nutrition by the arbuscular mycorrhiza may have contributed to reduced damage by P. parasitica in tomato (see also Davis and Menge 1980; Graham and Menge 1982), other mechanisms must be involved in the bioprotective effects. Benhamou ...
... Trotta et al. (1996) demonstrated that although improved phosphate nutrition by the arbuscular mycorrhiza may have contributed to reduced damage by P. parasitica in tomato (see also Davis and Menge 1980; Graham and Menge 1982), other mechanisms must be involved in the bioprotective effects. Benhamou ...
Increased Susceptibility of the Sickle Cell Membrane
... antioxidant, and 1 mmol/L desferal, an iron chelator. Both ascorbate and desferal added alone with tBHP were effective in preventing inhibition of the basal and calmodulin-stimulated Ca2+ Mg2’-ATPase activities in normal membranes, but in sickle cell membranes only the addition of ascorbate and desf ...
... antioxidant, and 1 mmol/L desferal, an iron chelator. Both ascorbate and desferal added alone with tBHP were effective in preventing inhibition of the basal and calmodulin-stimulated Ca2+ Mg2’-ATPase activities in normal membranes, but in sickle cell membranes only the addition of ascorbate and desf ...
Monoclonal antibody 7G3 recognizes the N
... that stimulates production of hematopoietic cells from multiple lineages, including neutrophils, eosinophils, monocytes, megakaryocytes, erythroid cells, basophils, and B cells.'-6 Recently, IL-3 has also been shown to regulate vascular endothelial cell functions, enhancing adhesion molecule express ...
... that stimulates production of hematopoietic cells from multiple lineages, including neutrophils, eosinophils, monocytes, megakaryocytes, erythroid cells, basophils, and B cells.'-6 Recently, IL-3 has also been shown to regulate vascular endothelial cell functions, enhancing adhesion molecule express ...
Mechanisms of Host Plant Infection by the Parasitic Angiosperm
... Like all forms of life, plants exist in a constant interplay with biotic and abiotic factors. After several hundred million years of diversifying, plants occupy many niches; from the living fossil Welwitschia in the desert to the tiny aquatic Wolffia, the insect-eating Venus flytrap or the research ...
... Like all forms of life, plants exist in a constant interplay with biotic and abiotic factors. After several hundred million years of diversifying, plants occupy many niches; from the living fossil Welwitschia in the desert to the tiny aquatic Wolffia, the insect-eating Venus flytrap or the research ...
Plasma membrane repair in plants
... plasma membrane repair for animal annexins A1 and A2 came with the observation that their expression was coregulated in mice affected with limb-girdle muscular dystrophy caused by a mutation in the dysferlin gene [57]. Further experiments confirmed that dysferlin is enriched in membrane patches near ...
... plasma membrane repair for animal annexins A1 and A2 came with the observation that their expression was coregulated in mice affected with limb-girdle muscular dystrophy caused by a mutation in the dysferlin gene [57]. Further experiments confirmed that dysferlin is enriched in membrane patches near ...
Enzymatic reduction of disulfide bonds in lysosomes
... Intracellular Localization. The Burkitt’s lymphoma cell line Raji was examined by electron microscopy. In MHC class IIexpressing cells, late endosomes (LEs) and lysosomes have collectively been termed MIICs (31). Recently, an additional type of endosome was identified and characterized in Blymphocyt ...
... Intracellular Localization. The Burkitt’s lymphoma cell line Raji was examined by electron microscopy. In MHC class IIexpressing cells, late endosomes (LEs) and lysosomes have collectively been termed MIICs (31). Recently, an additional type of endosome was identified and characterized in Blymphocyt ...
Dependence of an Adenosine-Activated Potassium Current on a
... potassium in the bathing media,where reversal potentials were obtained by interpolating through 0 current on plots such as B. Each average is from 2-4 cells. Potassium chloride replaced sodium chloride to elevate exnacellular potassium. The slope of the best-fit line shown is - 55 mV. ...
... potassium in the bathing media,where reversal potentials were obtained by interpolating through 0 current on plots such as B. Each average is from 2-4 cells. Potassium chloride replaced sodium chloride to elevate exnacellular potassium. The slope of the best-fit line shown is - 55 mV. ...
sperm aster in rabbit zygotes: its structure and
... the male and female pronuclei from their site of central region, the centrosphere, and (b) a cortical formation to a region within the zygote where they area, which gives the body its stellate appearance. become associated and form the embryonic ge- Both regions are richly endowed with microtubules ...
... the male and female pronuclei from their site of central region, the centrosphere, and (b) a cortical formation to a region within the zygote where they area, which gives the body its stellate appearance. become associated and form the embryonic ge- Both regions are richly endowed with microtubules ...
Regulation of DNA replication during development
... 1 (Cdt1), ORC loads a double hexamer of the minichromosome maintenance proteins 2-7 (Mcm2-Mcm7) onto DNA (Remus et al., 2009) (Fig. 1A). Pre-RC complexes are ‘licensed’, or poised for replication, but are incapable of initiating DNA synthesis because the helicase is loaded in an inactive state. Acti ...
... 1 (Cdt1), ORC loads a double hexamer of the minichromosome maintenance proteins 2-7 (Mcm2-Mcm7) onto DNA (Remus et al., 2009) (Fig. 1A). Pre-RC complexes are ‘licensed’, or poised for replication, but are incapable of initiating DNA synthesis because the helicase is loaded in an inactive state. Acti ...
Precipitation of calcium, magnesium, strontium and barium in tissues
... grown in substrates with elevated metal levels, and studying biomineralisation may provide valuable information to select suitable plant species for growth on disturbed land, for example, mined soil that is calcium-rich. In our previous study, an abundance of crystals containing calcium was observed ...
... grown in substrates with elevated metal levels, and studying biomineralisation may provide valuable information to select suitable plant species for growth on disturbed land, for example, mined soil that is calcium-rich. In our previous study, an abundance of crystals containing calcium was observed ...
bZIP transcription factor interactions regulate DIF
... biochemical interactions between DimA and DimB provides evidence that their ability to regulate diverse targets in response to DIF1 is partly due to their ability to form homo- and heterodimeric complexes. DimA and DimB are therefore direct regulators of cellular responses to DIF-1. ...
... biochemical interactions between DimA and DimB provides evidence that their ability to regulate diverse targets in response to DIF1 is partly due to their ability to form homo- and heterodimeric complexes. DimA and DimB are therefore direct regulators of cellular responses to DIF-1. ...
Full Paper - Calcutta Research Group
... higher education and urbanisation through concerted community efforts, but continuing to be strongly rooted in the agricultural economy, the Kammas finally succeeded in replacing the Brahmin socio-cultural hegemony with their own. The Green Revolution of the late 1960s and early 1970s stimulated the ...
... higher education and urbanisation through concerted community efforts, but continuing to be strongly rooted in the agricultural economy, the Kammas finally succeeded in replacing the Brahmin socio-cultural hegemony with their own. The Green Revolution of the late 1960s and early 1970s stimulated the ...
- ORCA - Cardiff University
... is part of homeostasis and maintenance in most organs and tissues. The situation in the nervous system is principally different, as the vast majority of neurons undergo their last round of cell division early in development. Soon after exiting the cell cycle, neurons start elongating axons to innerv ...
... is part of homeostasis and maintenance in most organs and tissues. The situation in the nervous system is principally different, as the vast majority of neurons undergo their last round of cell division early in development. Soon after exiting the cell cycle, neurons start elongating axons to innerv ...
Document
... sponse to RBC loss, have a longer lifespan. Without performing a correction for these so-called ‘shift’ reticulocytes, the ...
... sponse to RBC loss, have a longer lifespan. Without performing a correction for these so-called ‘shift’ reticulocytes, the ...
Oct-4 controls cell-cycle progression of embryonic stem cells
... Mouse and human ES (embryonic stem) cells display unusual proliferative properties, which are achieved by symmetric cell division, while maintaining their pluripotency. These properties can be regulated by transcriptional control in the nucleus through extracellular signals [1]. The oct-4 gene, also ...
... Mouse and human ES (embryonic stem) cells display unusual proliferative properties, which are achieved by symmetric cell division, while maintaining their pluripotency. These properties can be regulated by transcriptional control in the nucleus through extracellular signals [1]. The oct-4 gene, also ...
Mitosis
Mitosis is a part of the cell cycle in which chromosomes in a cell nucleus are separated into two identical sets of chromosomes, each in its own nucleus. In general, mitosis (division of the nucleus) is often followed by cytokinesis, which divides the cytoplasm, organelles and cell membrane into two new cells containing roughly equal shares of these cellular components. Mitosis and cytokinesis together define the mitotic (M) phase of an animal cell cycle—the division of the mother cell into two daughter cells, genetically identical to each other and to their parent cell.The process of mitosis is divided into stages corresponding to the completion of one set of activities and the start of the next. These stages are prophase, prometaphase, metaphase, anaphase, and telophase. During mitosis, the chromosomes, which have already duplicated, condense and attach to fibers that pull one copy of each chromosome to opposite sides of the cell. The result is two genetically identical daughter nuclei. The cell may then divide by cytokinesis to produce two daughter cells. Producing three or more daughter cells instead of normal two is a mitotic error called tripolar mitosis or multipolar mitosis (direct cell triplication / multiplication). Other errors during mitosis can induce apoptosis (programmed cell death) or cause mutations. Certain types of cancer can arise from such mutations.Mitosis occurs only in eukaryotic cells and the process varies in different organisms. For example, animals undergo an ""open"" mitosis, where the nuclear envelope breaks down before the chromosomes separate, while fungi undergo a ""closed"" mitosis, where chromosomes divide within an intact cell nucleus. Furthermore, most animal cells undergo a shape change, known as mitotic cell rounding, to adopt a near spherical morphology at the start of mitosis. Prokaryotic cells, which lack a nucleus, divide by a different process called binary fission.