Implantable carotid sinus baroreflex device for the treatment of drug
... Baroreflex stimulation is a novel therapy for drug-resistant hypertension. The largest data series (n=276) demonstrated a sustained reduction in both systolic and diastolic blood pressure by the study end (22 to 53 months’ follow-up). However, the Rheos Pivotal Trial was a randomised crossover trial ...
... Baroreflex stimulation is a novel therapy for drug-resistant hypertension. The largest data series (n=276) demonstrated a sustained reduction in both systolic and diastolic blood pressure by the study end (22 to 53 months’ follow-up). However, the Rheos Pivotal Trial was a randomised crossover trial ...
What do we know about the natural history of severe symptomatic
... vascular accident, respiratory insufficiency, renal failure and reduced left ventricular function, are independent predictors of in-hospital mortality in octogenarians [3,5,6] . At present, patients who are high-risk candidates for surgical valve replacement may be offered transcatheter aortic valve ...
... vascular accident, respiratory insufficiency, renal failure and reduced left ventricular function, are independent predictors of in-hospital mortality in octogenarians [3,5,6] . At present, patients who are high-risk candidates for surgical valve replacement may be offered transcatheter aortic valve ...
ENTC 4350
... more sensitive than healthy hearts to any signal that arrive during the latter part of the QRS complex or the T wave, and such a weakened heart will go into fibrillation if a pacemaker beat and either of these signals happen to coincide. ...
... more sensitive than healthy hearts to any signal that arrive during the latter part of the QRS complex or the T wave, and such a weakened heart will go into fibrillation if a pacemaker beat and either of these signals happen to coincide. ...
Arrhythmogenic Right Ventricular Cardiomyopathy/Dysplasia
... susceptible to ventricular arrhythmias with a re-entry mechanism.4 Case presentation A 51-year-old woman, with no risk factors for coronary artery disease, presented with primary complaint dyspnoea and fatigue on slight effort. At the age of 36 she had undergone surgery and radiotherapy for laryngea ...
... susceptible to ventricular arrhythmias with a re-entry mechanism.4 Case presentation A 51-year-old woman, with no risk factors for coronary artery disease, presented with primary complaint dyspnoea and fatigue on slight effort. At the age of 36 she had undergone surgery and radiotherapy for laryngea ...
Escape-capture bigeminy caused by blocked - Heart
... the first sinus beat of the next ensuing 3: I sequence. 2) A basic 3:2 atrioventricular block; the blocked impulse allowing an atrioventricular nodal (or ventricular) escape beat which is coincident with, and dissociated from, the next sinus impulse - the first of the ensuing 3:2 atrioventricular se ...
... the first sinus beat of the next ensuing 3: I sequence. 2) A basic 3:2 atrioventricular block; the blocked impulse allowing an atrioventricular nodal (or ventricular) escape beat which is coincident with, and dissociated from, the next sinus impulse - the first of the ensuing 3:2 atrioventricular se ...
- Improving Medical Statistics
... little effect on cholesterol in this small group, that oat bran was without significant effect. This example also examines how the conclusions of a meta-analysis can be biased. The fourth example illustrates the hazards of inappropriate subgroup analysis. www.improvingmedicalstatistics.com ...
... little effect on cholesterol in this small group, that oat bran was without significant effect. This example also examines how the conclusions of a meta-analysis can be biased. The fourth example illustrates the hazards of inappropriate subgroup analysis. www.improvingmedicalstatistics.com ...
Effects of physical exercises on the ventricular myocardium
... 3.1 Functional myocardial structure According to Hudlicka and Brown (1996), a normal adult myocardium consists of around 80% of myocytes and 20% of cellular matrix, which contains conjunctive tissue and blood vessels, among others. These proportions are different in distinct development stages and ...
... 3.1 Functional myocardial structure According to Hudlicka and Brown (1996), a normal adult myocardium consists of around 80% of myocytes and 20% of cellular matrix, which contains conjunctive tissue and blood vessels, among others. These proportions are different in distinct development stages and ...
Differentiating Types Of Wide-Complex Tachycardia To Determine
... AV re-entrant tachycardia). (See Figure 2.) Frequently, these rhythms present as narrow-complex tachycardia. However, conduction delay can occur in the setting of more-rapid heart rates, and rate-related refractory (or fatigue) conducting fibers of the AV nodal-His-Purkinje system will lead to QRS w ...
... AV re-entrant tachycardia). (See Figure 2.) Frequently, these rhythms present as narrow-complex tachycardia. However, conduction delay can occur in the setting of more-rapid heart rates, and rate-related refractory (or fatigue) conducting fibers of the AV nodal-His-Purkinje system will lead to QRS w ...
estimating myocardial fiber orientations
... The method was able to map the fibers accurately for both healthy as well as for failing hearts that had left bundle branch blocks. Although, the percentage of voxels having an error of less than 10◦ was lower in the failing hearts as compared to the healthy ones, we observe that most of these errors ...
... The method was able to map the fibers accurately for both healthy as well as for failing hearts that had left bundle branch blocks. Although, the percentage of voxels having an error of less than 10◦ was lower in the failing hearts as compared to the healthy ones, we observe that most of these errors ...
Syncope in congestive heart failure
... A major limitation of the ICD-based analysis is the use of appropriate ICD therapies as a measure of outcome. Many ventricular tachycardia episodes terminate spontaneously without event. Therefore, ICD shocks may not be a reliable surrogate for sudden cardiac death [20, 21]. A recent post hoc analys ...
... A major limitation of the ICD-based analysis is the use of appropriate ICD therapies as a measure of outcome. Many ventricular tachycardia episodes terminate spontaneously without event. Therefore, ICD shocks may not be a reliable surrogate for sudden cardiac death [20, 21]. A recent post hoc analys ...
Idiopathic fascicular left ventricular tachycardia: Linear
... be entrained with concealed fusion over a region of the septum with entrance sites at the more basal septum and exit sites described toward the more mid to apical inferior septum. Characteristics supporting a smaller reentrant or possibly a triggered mechanism include (1) the His bundle can be activ ...
... be entrained with concealed fusion over a region of the septum with entrance sites at the more basal septum and exit sites described toward the more mid to apical inferior septum. Characteristics supporting a smaller reentrant or possibly a triggered mechanism include (1) the His bundle can be activ ...
Pulmonary Vein Isolation Using a Visually
... PVs. Throughout the procedure, intravenous heparin was administered as boluses and a continuous infusion to maintain an activated clotting time >300 sec. The deflectable sheath was positioned at the ostium of the target PV and the VGLA catheter was advanced and inflated. Ablation lesions were placed ...
... PVs. Throughout the procedure, intravenous heparin was administered as boluses and a continuous infusion to maintain an activated clotting time >300 sec. The deflectable sheath was positioned at the ostium of the target PV and the VGLA catheter was advanced and inflated. Ablation lesions were placed ...
AHEART August 46/2 - AJP
... ratio) (Fig. 1). For the case of 50 points, short-term predictability was paradoxically improved by the addition of noise; this may relate to boundary and/or aliasing effects specific to sampling 50 points of the function sin (2t/25) ⫹ sin (2t/5). In contrast, although the chaotic system demonstra ...
... ratio) (Fig. 1). For the case of 50 points, short-term predictability was paradoxically improved by the addition of noise; this may relate to boundary and/or aliasing effects specific to sampling 50 points of the function sin (2t/25) ⫹ sin (2t/5). In contrast, although the chaotic system demonstra ...
Hypertension and arrhythmia: blood pressure control
... and T wave morphology analysis. QT interval dispersion and dynamicity QT interval dispersion is the difference between maximal and minimal QT intervals on a 12-lead surface electrocardiogram[30]. It is thought to represent the degree of repolarization inhomogeneity in the heart with abnormal values p ...
... and T wave morphology analysis. QT interval dispersion and dynamicity QT interval dispersion is the difference between maximal and minimal QT intervals on a 12-lead surface electrocardiogram[30]. It is thought to represent the degree of repolarization inhomogeneity in the heart with abnormal values p ...
Cardiology Board Review
... of the aorta, or hypoplastic left heart syndrome. In such patients, tachypnea is caused by pulmonary congestion that results from decreased filling of the failing left heart. A gallop rhythm may be audible on auscultation, due to filling of the noncompliant left ventricle. The tachypnea exacerbates ...
... of the aorta, or hypoplastic left heart syndrome. In such patients, tachypnea is caused by pulmonary congestion that results from decreased filling of the failing left heart. A gallop rhythm may be audible on auscultation, due to filling of the noncompliant left ventricle. The tachypnea exacerbates ...
studies of cardio-regulation in the cockroach, periplaneta americana
... right) of the third abdominal ganglion affected not only the fourth abdominal chamber of the heart but the entire abdominal portion of the dorsal vessel. The responses of the thoracic part of the heart were not examined at this time but there remains a distinct possibility that the entire heart is a ...
... right) of the third abdominal ganglion affected not only the fourth abdominal chamber of the heart but the entire abdominal portion of the dorsal vessel. The responses of the thoracic part of the heart were not examined at this time but there remains a distinct possibility that the entire heart is a ...
Single coronary artery incidence in 215,140 patients undergoing
... In the analysis of Yamanaka et al. [23] with 126,595 patients, the incidence of SCA was found to be 0.045%. In this analysis, there were 20 patients with type L-I, 11 patients with type L-II, 1 patient with type R-I, 19 patients with type R-II and 5 patients with type R-III [23]. In a retrospective ...
... In the analysis of Yamanaka et al. [23] with 126,595 patients, the incidence of SCA was found to be 0.045%. In this analysis, there were 20 patients with type L-I, 11 patients with type L-II, 1 patient with type R-I, 19 patients with type R-II and 5 patients with type R-III [23]. In a retrospective ...
Exercise Test Review Article
... measurements at 3·5 min of recovery, from lead V5, 60 ms after the QRS complex (ST60), were better than all other single measurements. Further, prediction equations that included clinical and exercise-test data showed the greatest diagnostic power. In a new approach, Michaelides and colleagues exami ...
... measurements at 3·5 min of recovery, from lead V5, 60 ms after the QRS complex (ST60), were better than all other single measurements. Further, prediction equations that included clinical and exercise-test data showed the greatest diagnostic power. In a new approach, Michaelides and colleagues exami ...
CPAP decreases plasma levels of soluble obstructive sleep apnoea
... from the present authors’ Madrid metropolitan area of healthcare assigned to the Hospital La Paz (Madrid, Spain), who had undergone a routine health examination in the previous 3 months. A control subject similar in sex, age (¡2 yrs), weight (¡2 kg) and height (¡5 cm) with regard to the two precedin ...
... from the present authors’ Madrid metropolitan area of healthcare assigned to the Hospital La Paz (Madrid, Spain), who had undergone a routine health examination in the previous 3 months. A control subject similar in sex, age (¡2 yrs), weight (¡2 kg) and height (¡5 cm) with regard to the two precedin ...
Prognostic benefits of heart rate reduction in cardiovascular disease
... Increased heart rate is associated with high blood pressure and metabolic disturbances that lead to hypertension, atherosclerosis and increased cardiovascular morbidity and mortality. In this respect, elevated heart rate can be considered a marker of risk. Whole body temperature and energy needs are ...
... Increased heart rate is associated with high blood pressure and metabolic disturbances that lead to hypertension, atherosclerosis and increased cardiovascular morbidity and mortality. In this respect, elevated heart rate can be considered a marker of risk. Whole body temperature and energy needs are ...
Electrocardiography Heart Anatomy
... Resumes pacing as if nothing happened Same P waves before and after ...
... Resumes pacing as if nothing happened Same P waves before and after ...
The Acute Effects of Therapeutic Activities on Heart Rate and Blood
... used in these types of research, no present study exists summarizing these results. Knowledge about the acute effects of HR and BP in relation to therapeutic activities is important in order to provide safer and more accurate treatment prescription, to prevent complications and delayed recovery, and ...
... used in these types of research, no present study exists summarizing these results. Knowledge about the acute effects of HR and BP in relation to therapeutic activities is important in order to provide safer and more accurate treatment prescription, to prevent complications and delayed recovery, and ...
Transcatheter aortic valve implantation: emerging role in poor left
... an improvement in LV ejection fraction at one year following TAVI in LGLEF severe aortic stenosis, however, changes in LV mass or volumes were not reported.8 In this non-randomized observational study, the improvement in ejection fraction at one year was better in TAVI patients compared to conventio ...
... an improvement in LV ejection fraction at one year following TAVI in LGLEF severe aortic stenosis, however, changes in LV mass or volumes were not reported.8 In this non-randomized observational study, the improvement in ejection fraction at one year was better in TAVI patients compared to conventio ...
Aspirin Therapy for Patients with Stable CAD
... • Concomitant antiplatelet drugs appeared to increase the risk for major bleeding in RE‐LY without affecting the advantages of dabigatran over warfarin • Dabigatran 150mg BID reduced the primary outcome of stroke and systemic embolism compared to warfarin • However, this effect seemed attenuated ...
... • Concomitant antiplatelet drugs appeared to increase the risk for major bleeding in RE‐LY without affecting the advantages of dabigatran over warfarin • Dabigatran 150mg BID reduced the primary outcome of stroke and systemic embolism compared to warfarin • However, this effect seemed attenuated ...
Cardiac contractility modulation
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Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.