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Electrocardiographic Characteristics and SCN5A Mutations in
Electrocardiographic Characteristics and SCN5A Mutations in

tachycardia - Campbell M Gold.com Home
tachycardia - Campbell M Gold.com Home

... Longstanding persistent *atrial fibrillation - this usually lasts for longer than a year. ...
Transcatheter aortic valve implantation: emerging role in poor left
Transcatheter aortic valve implantation: emerging role in poor left

... an improvement in LV ejection fraction at one year following TAVI in LGLEF severe aortic stenosis, however, changes in LV mass or volumes were not reported.8 In this non-randomized observational study, the improvement in ejection fraction at one year was better in TAVI patients compared to conventio ...
Electrocardiography Heart Anatomy
Electrocardiography Heart Anatomy

... Resumes pacing as if nothing happened Same P waves before and after ...
Arrhythmia-Induced Cardiomyopathies
Arrhythmia-Induced Cardiomyopathies

... Council do not necessarily reflect the views of the Journal of the American College of Cardiology or the ACC. From the *Division of Cardiovascular Medicine, University of Louisville, Louisville, Kentucky; yDivision of Pediatric Cardiology, University of Utah, Salt Lake City, Utah; zDivision of Cardio ...
Aspirin Therapy for Patients with Stable CAD
Aspirin Therapy for Patients with Stable CAD

... • Concomitant antiplatelet drugs appeared to increase the risk  for major bleeding in RE‐LY without affecting the advantages  of dabigatran over warfarin • Dabigatran 150mg BID reduced the primary outcome of stroke  and systemic embolism compared to warfarin • However, this effect seemed attenuated  ...
CPAP decreases plasma levels of soluble obstructive sleep apnoea
CPAP decreases plasma levels of soluble obstructive sleep apnoea

... from the present authors’ Madrid metropolitan area of healthcare assigned to the Hospital La Paz (Madrid, Spain), who had undergone a routine health examination in the previous 3 months. A control subject similar in sex, age (¡2 yrs), weight (¡2 kg) and height (¡5 cm) with regard to the two precedin ...
Intermediate-Signal-Intensity Late Gadolinium
Intermediate-Signal-Intensity Late Gadolinium

Pathophysiology of heart failure following myocardial infarction
Pathophysiology of heart failure following myocardial infarction

... progression of left ventricular dysfunction and remodelling in dogs with chronic heart failure induced by intracoronary microembolisations that were discontinued when left ventricular ejection fraction was between 30–40%.11 The difference between the eplerenone group and a control group in left vent ...
RV Electrical Activation in Heart Failure During Right, Left, and
RV Electrical Activation in Heart Failure During Right, Left, and

Imaging pitfalls, normal anatomy, and anatomical variants that can
Imaging pitfalls, normal anatomy, and anatomical variants that can

... the display of cardiac anatomy and pathology. The use of CT scanners with 64 or more detectors is now standard and ECG-gating capabilities are widely available. In this article, we review normal cardiac anatomy and commonly encountered pitfalls using a chamber-specific approach. ...
Journal of Cardiovascular Magnetic Resonance
Journal of Cardiovascular Magnetic Resonance

... renal, breast, and hematologic malignancies. Unfortunately, an unintended consequence of many of the therapies that have contributed to this improvement in cancer-free survival has been the increasingly recognized evolution of cardiovascular (CV) events [1-12]. Several recently published research st ...
Cardiogenic Shock - The Association of Physicians of India
Cardiogenic Shock - The Association of Physicians of India

... with antiarrhythmic drugs, cardioversion, or pacing. Cardiology consultation has been shown to be associated with improved outcomes in patients with myocardial infarction and is strongly indicated in the setting of cardiogenic shock. Inotropes In patients with inadequate tissue perfusion and adequat ...
Computational cardiac atlases: from patient to population and back Review Article
Computational cardiac atlases: from patient to population and back Review Article

... of local wall motion. However, these images provide detailed information on regional wall motion during diastole and systole, which can be combined with other imaging or clinical data to yield greater understanding of underlying disease processes. Model-based analysis tools (Fig. 2) allow the calcul ...
4
4

... ventricular ejection fraction (RVEF) and survival in patients with pulmonary arterial hypertension (PAH) under PAH-targeted therapies. Background: Despite the fact that medical therapies reduce PVR, the prognosis of patients with PAH is still poor. The primary cause of death is right ventricular (RV ...
Hypoplastic left heart syndrome
Hypoplastic left heart syndrome

... that survival improved with increased experience of intervention for HLHS2. This is likely to reflect improved surgical technique and perioperative care. The second and third stages of the Norwood protocol have a much lower mortality than the first stage, typically around 5% or less2,22,24,25. The l ...
L6-Resources2OptionalslidesetECGrhythm
L6-Resources2OptionalslidesetECGrhythm

... -Constant PR interval…then dropped beat -Block always BELOW AV node (more serious) -Never normal -Likely needs a pacemaker ...
9 Evaluation and Emergency Treatment of Criticlly Ill Neonate
9 Evaluation and Emergency Treatment of Criticlly Ill Neonate

... Although a significant heart murmur usually suggests a cardiac basis for the cyanosis, several of the more severe cardiac defects (transposition of the great vessels) may not initially be associated with a murmur. Heart murmurs. 1. Innocent heart murmurs: More than 50% of full-term newborn infants ( ...
Arrhythmias in Children - Jacobi Emergency Medicine
Arrhythmias in Children - Jacobi Emergency Medicine

... • EAT – Ectopic Atrial Tachycardia • Atrial ectopy from a single area of atrial myocardium other than sinus node • Commonly results in ventricular dysfunction ...
Diastolic Dysfunction - UCSF | Department of Medicine
Diastolic Dysfunction - UCSF | Department of Medicine

... Clinical definition: 35-40% of men with CHF, 65-75% of women with CHF o Cardiac dysfunction with normal EF (>50%) or with findings of diastolic dysfunction on echo/cath o Difficulties: timing of echo in relation to treatment, mixed etiologies o Asymptomatic diastolic dysfunction: Mayo Clinic study - ...
SICI-GISE
SICI-GISE

... General Description................................................................................................................. 26 ...
HFA ESC Palliative Care Statement - escardio.org
HFA ESC Palliative Care Statement - escardio.org

... unfamiliar with the principles and practice of this clinical specialty.9 A glossary of terms used to discuss the care that patients need during advanced stages of disease to the end of life are described in Box 2. Other barriers confounding the provision of palliative care to those with advanced HF ...
DEL-25675 LVAD Patient Info Booklet CO-11.indd
DEL-25675 LVAD Patient Info Booklet CO-11.indd

... • Stroke (results from the brain being depleted of oxygen) • Right Heart Failure which may require a temporary mechanical support device to your right heart (RVAD; most will be removed after the right side has stabilized) Your VAD surgeon will explain any increased risks that you may have. It is imp ...
Heart Murmurs in Pediatric Patients: When Do You Refer?
Heart Murmurs in Pediatric Patients: When Do You Refer?

... Because of the increased volume of blood in the right ventricle in the patient with an atrial septai defect, the S, always sounds as if the patient has taken a deep breath. This means that the volume of blood in the right ventricle Is increased and it takes longer for the ventricle to eject its cont ...
Noninvasive Assessment of Myocardial Composition
Noninvasive Assessment of Myocardial Composition

... conditions is an important compensatory mechanism that tends to minimize abnormalities in myocardial stress related to the inciting load.4 However, recent See p 925 studies have indicated that hypertrophied muscle differs from normal muscle in many respects, including its structure, mechanical prope ...
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Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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