• Study Resource
  • Explore
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Bicuspid pulmonary valve without associated cardiac anomalies: a
Bicuspid pulmonary valve without associated cardiac anomalies: a

... FERNÁNDEZ, DURÁN et al., 1998). The present report emphasizes the fact that an isolated bicuspid anomaly of the pulmonary valve may be compatible with normal cardiac anatomy and physiology. Though very unique and rare in its incidence, a bifoliate pulmonary valve can exist without other expected car ...
Mortality in patients with TIMI 3 flow after PCI in relation to time delay
Mortality in patients with TIMI 3 flow after PCI in relation to time delay

... presence of other comorbidities or socio-demographic factors affect the time from symptom onset to treatment and outcomes, hence may impose a selection bias34-36. For instance, patients with more severe disease and worse prognosis may present earlier, those presenting later are typically low- risk p ...
CT IMAGING OF A CASE WITH BIVENTRICULAR HYPERTROPHIC
CT IMAGING OF A CASE WITH BIVENTRICULAR HYPERTROPHIC

... BIVENTRICULAR HYPERTROPHY ...
Clyde W. Yancy Donna M. Mancini, Peter S. Rahko, Marc A. Silver
Clyde W. Yancy Donna M. Mancini, Peter S. Rahko, Marc A. Silver

... affect treatment outcomes, healthcare providers should make every effort to engage the patient in active participation with prescribed treatment. The ACCF/AHA Task Force on Practice Guidelines makes every effort to avoid actual, potential, or perceived conflict of interest that may arise as a result ...
ECG-correlated imaging of the heart with subsecond
ECG-correlated imaging of the heart with subsecond

... tive temporal resolution as given in the results section will be slightly lower than because it is calculated as the full-width at tenth maximum (FWTM) of the phase sensitivity profile because this represents the contributions of the cardiac phases to the final image more adequately. Fig. 2 shows a ...
The importance of mechano-electrical feedback and inertia in
The importance of mechano-electrical feedback and inertia in

... Keywords: Electro-mechanics; Excitation–contraction; Cardiac mechanics; Finite element analysis; Abaqus ...
Features of Carcinoid Heart Disease Identified by 2
Features of Carcinoid Heart Disease Identified by 2

... maneuver. The presence of patent foramen ovale was defined as the presence of at least 3 microbubbles in the left atrium within 3 cardiac cycles of contrast visualization in right atrium. The degree of shunting was classified as mild if 3 to 9 microbubbles appeared, moderate if 10 to 30 microbubbles ...
Cardiac Computed Tomographic Angiography (Cardiac CTA)
Cardiac Computed Tomographic Angiography (Cardiac CTA)

... Contrast-enhanced cardiac CT angiography can be performed using either multidetector-row CT (MDCT) or electron beam CT (EBCT). Multiple manufacturers have received FDA 510(k) clearance to market MDCT machines equipped with at least 16 detector rows and at least two models of EBCT machines have been ...
Left Ventricular Hypertrophy Is a Common Echocardiographic
Left Ventricular Hypertrophy Is a Common Echocardiographic

... due to respiratory events lead to increased sympathetic nervous system activity, with subsequent elevation in urinary and plasma catecholamines levels. Consequently, the adverse consequences of repetitive episodes of increased afterload on the heart during sleep may persist into the daytime. In this ...
Valve-in-Valve Transcatheter Aortic and Mitral Replacement
Valve-in-Valve Transcatheter Aortic and Mitral Replacement

... in the elderly population5 will inevitably lead to further increased use of this technology in the future. Currently, there are two transcatheter heart valves (THVs) approved in the United States, the balloonexpandable Sapien valve (Edwards Lifesciences) and the self-expandable CoreValve device (Med ...
Full Text [Download PDF]
Full Text [Download PDF]

... pmVSDs has a high clinical significance. ...
Muscle Tissue
Muscle Tissue

... However, like smooth muscle tissue, it is involuntary. Cardiac muscle differ from striated muscle in the following aspects: -they are shorter, the striations are not so obvious, - the sarcolemma is thinner and not clearly discernible, - there is only one nucleus present in the centre of each cardiac ...
Incidence and etiology of sudden cardiac death in young athletes
Incidence and etiology of sudden cardiac death in young athletes

... channelopathies (congenital long or short QT syndrome, Brugada syndrome, catecholaminergic polymorphic ventricular tachycardia) have in common the inherent risk for life-threatening arrhythmias in affected young individuals [25, 47]. Congenital long QT-syndrome (LQTS) is manifested by symptoms (sync ...
Multifocal Atrial Tachycardia in 2 Children
Multifocal Atrial Tachycardia in 2 Children

... has also been reported that prolonged and refractory MAT contributed to complications and final death.12,13 Therefore, MAT per se may not be so malignant, but an investigation is still obligatory. The management of MAT remains a big challenge at present. Considering the ineffectiveness of cardiovers ...
A Meta-Analysis of Remote Monitoring of Heart Failure Patients
A Meta-Analysis of Remote Monitoring of Heart Failure Patients

... reason for exclusion. Thus, 20 RCTs (3–22) and 12 cohort studies (23–34) were available. Six cohort studies had a between-arm and 6 had a within-arm (before-after) design. Study population. As shown in Table 2, RCTs were evenly distributed over the 9 years of literature reviewed, and 4 of them were ...
Echocardiographic Variables After Left Ventricular Assist Device
Echocardiographic Variables After Left Ventricular Assist Device

... surgery suggesting appropriate degree of LV unloading and an adequate forward flow would be important in determining clinical outcomes after the initial successful LVAD implantation. Methods and Results—We retrospectively analyzed various variables in echocardiographic examinations performed 30 days ...
How Accurate can Electrocardiogram Predict Left Ventricular
How Accurate can Electrocardiogram Predict Left Ventricular

... Approximately half of the patients with heart failure (HF) have preserved ejection fraction (HFpEF). Recent studies have shown that the pathophysiology of HFpEF, initially believed to be principally due to diastolic dysfunction, is more complex. Appreciation of this complexity has shed new light ont ...
Research ReviewTM
Research ReviewTM

... A small subset of patients with CHD are diagnosed in adulthood, for example, adults with an atrial septal defect are often diagnosed by echocardiography during screening of an asymptomatic murmur. Some young adults with coarctation are diagnosed during screening for hypertension. Other patients who ...
Inflammatory Cardiovascular Diseases Pericarditis
Inflammatory Cardiovascular Diseases Pericarditis

...  Hypotension, Distended neck veins, Muffled heart sounds ...
Frequent Premature Ventricular Contractions in
Frequent Premature Ventricular Contractions in

... the requirement that he take verapamil SR 240 mg z d21. In The spaceflight participant underwent overnight oxiJanuary while taking verapamil, a 24-h Holter monitor metry to rule out sleep disordered breathing that could study showed a single PVC. The downside of this therapy play a role in his frequ ...
lhnsient Digitoxic Double Tachycardia
lhnsient Digitoxic Double Tachycardia

... several hours to control atrial fibrillation with rapid ventricular response in a patient who gave no history of being on digitalis is considered within therapeutic range. At that time the renal insufficiency secondary to marked dehydration was not appreciated. However, renal insufficiency does not ...
Right ventricular failure in patients with the HeartMate
Right ventricular failure in patients with the HeartMate

... insufficient.1 Although cardiac transplantation remains an attractive therapeutic option for select patients, only 2000 heart transplantations are performed each year in the United States, largely as a result of donor shortages.2 This continued limitation underscores the need for alternative avenues ...
Copyright Information of the Article Published Online TITLE
Copyright Information of the Article Published Online TITLE

... have an embolic mechanism and a significant proportion are likely to be related to undiagnosed AF. Ziegler et al[13] analysed data from patients at risk of thromboembolism (stroke/TIA) who had implantable cardiac devices capable of recording atrial arrhythmias. They identified newly detected episode ...
NSTEMI standing orders
NSTEMI standing orders

... ADMIT – Unstable Angina/Non–ST-Elevation MI (NSTEMI) ACC/AHA Class I Recommendations* in Bold EARLY CONSERVATIVE STRATEGY (Low- or Intermediate-Risk Patients) Check/Initial/Date _____/_____ ...
Understanding Arrhythmias and your EP Procedure
Understanding Arrhythmias and your EP Procedure

... arrhythmia. More than two million people in the United States have this condition. If left untreated, the side effects of AF can be potentially life-threatening. During AF, the top chambers (atria) of the heart quiver, or fibrillate, in a rapid, irregular pattern. This arrhythmia is usually driven b ...
< 1 ... 165 166 167 168 169 170 171 172 173 ... 680 >

Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
  • studyres.com © 2025
  • DMCA
  • Privacy
  • Terms
  • Report