Incidence of, predictors for, and mortality associated with malignant
... Acute myocardial infarction patients are prone to developing life-threatening ventricular arrhythmias in the early phase of their event. Ischemia has a rapid and profound effect on the electrophysiological properties of the myocyte. Changes in the resting membrane potential and ionic fluxes during ...
... Acute myocardial infarction patients are prone to developing life-threatening ventricular arrhythmias in the early phase of their event. Ischemia has a rapid and profound effect on the electrophysiological properties of the myocyte. Changes in the resting membrane potential and ionic fluxes during ...
Arrhythmias in the developing heart
... one with supraventricular tachycardia and one with a second-degree AV block – associated with structural heart disease of all 614 foetuses with irregular heart rhythm. On the other hand, there is evidence that foetal arrhythmia may be associated with structural heart disease. Schmidt et al. (1991) r ...
... one with supraventricular tachycardia and one with a second-degree AV block – associated with structural heart disease of all 614 foetuses with irregular heart rhythm. On the other hand, there is evidence that foetal arrhythmia may be associated with structural heart disease. Schmidt et al. (1991) r ...
ECG Rhythm Interpretation December 16 & 18
... down the branches to the Purkinje fibers are the normal pacing sites of the heart. In a healthy person, an ECG should demonstrate an organized, sequential electrical impulse from its beginning at the SA node to its conclusion at the Purkinje fibers. Cardiac electrical activity immediately precedes t ...
... down the branches to the Purkinje fibers are the normal pacing sites of the heart. In a healthy person, an ECG should demonstrate an organized, sequential electrical impulse from its beginning at the SA node to its conclusion at the Purkinje fibers. Cardiac electrical activity immediately precedes t ...
SAED Guide revised Jan 2008 - Grampians Region Health
... This interval represents the time taken for the impulse to go through the atria, across the AV node and junction and down the Bundle of His. It is measured from the beginning of the P wave to the beginning of the QRS. Normal duration 0.12 – 0.20 seconds. QRS – This complex follows the P wave, PR i ...
... This interval represents the time taken for the impulse to go through the atria, across the AV node and junction and down the Bundle of His. It is measured from the beginning of the P wave to the beginning of the QRS. Normal duration 0.12 – 0.20 seconds. QRS – This complex follows the P wave, PR i ...
causes of right ventricular failure
... The RV is therefore well designed to accommodate increases in preload, but poorly designed to accommodate increases in afterload[13]. The RV can be divided into 2 components, the sinus or inflow region – extending from the TV and includes the trabeculated apical portion; and the conus or outflow tra ...
... The RV is therefore well designed to accommodate increases in preload, but poorly designed to accommodate increases in afterload[13]. The RV can be divided into 2 components, the sinus or inflow region – extending from the TV and includes the trabeculated apical portion; and the conus or outflow tra ...
Involvement of mitogen-activated protein kinases in adriamycin
... failure stage was analyzed using DNA microarrays analysis, and the results are shown in Table 2. ERK2 and p38 mRNA expression was decreased in the failing hearts in the ADR group. JNK gene expression was undetectable in both ADR and control groups. Expression of MEKK1, an ERK1/2 kinases upstream sti ...
... failure stage was analyzed using DNA microarrays analysis, and the results are shown in Table 2. ERK2 and p38 mRNA expression was decreased in the failing hearts in the ADR group. JNK gene expression was undetectable in both ADR and control groups. Expression of MEKK1, an ERK1/2 kinases upstream sti ...
Impaired left ventricular relaxation in type 2 diabetic rats is related to
... (yet) significantly impaired in diabetic rats at age 37 weeks. The functional impairment is related to the myocardial accumulation of CML, a prototypical advanced glycation end product (AGE). Taken together, these data support the hypothesis that AGEs can impair myocardial function and potentially c ...
... (yet) significantly impaired in diabetic rats at age 37 weeks. The functional impairment is related to the myocardial accumulation of CML, a prototypical advanced glycation end product (AGE). Taken together, these data support the hypothesis that AGEs can impair myocardial function and potentially c ...
emergency medical services management of st-elevation
... rather than the ideal time frame.47 Moreover, recent evidence suggests that acceptable reperfusion delay (i.e., the difference between time to balloon and time to drug) varies considerably depending on patient age, symptom duration, and infarct location.48 Fibrinolytic therapy may be preferred in pa ...
... rather than the ideal time frame.47 Moreover, recent evidence suggests that acceptable reperfusion delay (i.e., the difference between time to balloon and time to drug) varies considerably depending on patient age, symptom duration, and infarct location.48 Fibrinolytic therapy may be preferred in pa ...
Right Precordial T-Wave Inversion in Healthy Endurance Athletes
... (TWIV2-3) reflects lateral displacement of the heart such that the surface electrocardiographic (ECG) leads overlie a greater proportion of the right ventricle (RV). BACKGROUND TWIV2-3 on ECG is more frequently observed among endurance athletes (EAs) than in the general population, the underlying mec ...
... (TWIV2-3) reflects lateral displacement of the heart such that the surface electrocardiographic (ECG) leads overlie a greater proportion of the right ventricle (RV). BACKGROUND TWIV2-3 on ECG is more frequently observed among endurance athletes (EAs) than in the general population, the underlying mec ...
S1936878X14005592_mmc1 - JACC: Cardiovascular Imaging
... death is the initial manifestation of coronary disease in up to 18% of coronary events, and more than half of the sudden deaths occur without prior history of CAD (10,11). Particularly in diabetic patients without history of CAD, silent CAD is found frequently in up to 57% (8,12–15). There are many ...
... death is the initial manifestation of coronary disease in up to 18% of coronary events, and more than half of the sudden deaths occur without prior history of CAD (10,11). Particularly in diabetic patients without history of CAD, silent CAD is found frequently in up to 57% (8,12–15). There are many ...
Primary synovial sarcoma of the right heart involving the tricuspid
... translocations, the cytogenetic hallmark of SS. More than 90 % of SS present this translocation, which gives rise to a fusion gene, SS18 (SYT)-SSX (SSX1 or SSX2, or both) [5–17], whereas MPNST and carcinosarcoma lack SS18SSX fusions. The SS18 rearrangement was also observed in this case, and MPNST a ...
... translocations, the cytogenetic hallmark of SS. More than 90 % of SS present this translocation, which gives rise to a fusion gene, SS18 (SYT)-SSX (SSX1 or SSX2, or both) [5–17], whereas MPNST and carcinosarcoma lack SS18SSX fusions. The SS18 rearrangement was also observed in this case, and MPNST a ...
Contents - British Cardiovascular Society
... Spaces are limited and will be allocated on a first come, first served basis. The Harvey mannequin patient simulator will also feature in the session ‘How to examine the heart’ held in the exhibition hall on Tuesday 3 June at 13.00. ...
... Spaces are limited and will be allocated on a first come, first served basis. The Harvey mannequin patient simulator will also feature in the session ‘How to examine the heart’ held in the exhibition hall on Tuesday 3 June at 13.00. ...
Correction with blood T1 is essential when measuring post
... extra-cellular space even in the absence of scarring [1]. It can be used in various diseases such as acute or chronic myocardial infarction, various cardiomyopathies, valvular heart disease, or any disease that can cause myocardial fibrosis [2,3]. As the degree of left ventricular (LV) myocardial fi ...
... extra-cellular space even in the absence of scarring [1]. It can be used in various diseases such as acute or chronic myocardial infarction, various cardiomyopathies, valvular heart disease, or any disease that can cause myocardial fibrosis [2,3]. As the degree of left ventricular (LV) myocardial fi ...
326-1468-2-SP - International Cardiovascular Forum Journal
... In this study the BP recordings in the acute stage were significantly different between the two studied groups (P< 0.001).A study by Witt et al (2010), revealed that RV infarction is usually associated with depressed RV function, although it does not always lead to hemodynamic impairment(15). This i ...
... In this study the BP recordings in the acute stage were significantly different between the two studied groups (P< 0.001).A study by Witt et al (2010), revealed that RV infarction is usually associated with depressed RV function, although it does not always lead to hemodynamic impairment(15). This i ...
Potential of endothelin-1 and vasopressin
... of neurohumoral system Congestive heart failure is a syndrome caused by inability of the heart to pump sufficient blood for the perfusion of various organs in the body. Despite sufficient filling of chambers of the heart, cardiac output decreases and the heart is unable to meet the metabolic needs o ...
... of neurohumoral system Congestive heart failure is a syndrome caused by inability of the heart to pump sufficient blood for the perfusion of various organs in the body. Despite sufficient filling of chambers of the heart, cardiac output decreases and the heart is unable to meet the metabolic needs o ...
Intravenous magnesium for cardiac arrhythmias: jack of all trades
... Intravenous magnesium has a high therapeutic to toxic ratio and minimal negative inotropic effect [1], and as such, it has been used in the prevention and treatment of many different types of cardiac arrhythmia. Cardiac arrhythmia is, however, a common presentation of a diverse spectrum of diseases. ...
... Intravenous magnesium has a high therapeutic to toxic ratio and minimal negative inotropic effect [1], and as such, it has been used in the prevention and treatment of many different types of cardiac arrhythmia. Cardiac arrhythmia is, however, a common presentation of a diverse spectrum of diseases. ...
Targeting calcium transport in ischaemic heart disease
... myocardial I/R injury. These include: intracellular Ca2þ overload; the occurrence of a no reflow phenomenon due to cell swelling, impaired vascular relaxation or the formation of white cell plugs; and the formation of oxygen radicals. The oxyradical hypothesis of myocardial I/R has been reviewed in ...
... myocardial I/R injury. These include: intracellular Ca2þ overload; the occurrence of a no reflow phenomenon due to cell swelling, impaired vascular relaxation or the formation of white cell plugs; and the formation of oxygen radicals. The oxyradical hypothesis of myocardial I/R has been reviewed in ...
Successful management of left main coronary artery
... with mechanical valves has been performed for several years. Warfarin has been used in patients with mechanical heart valves to protect against thromboembolic complications; nevertheless, in these patients, thromboembolic event rates range from 0.5% to 1.7%. Acute occlusive embolism to the coronary ...
... with mechanical valves has been performed for several years. Warfarin has been used in patients with mechanical heart valves to protect against thromboembolic complications; nevertheless, in these patients, thromboembolic event rates range from 0.5% to 1.7%. Acute occlusive embolism to the coronary ...
Triage strategy for urgent management of cardiac tamponade: a
... surgical drainage that should not be delayed in any way by pericardiocentesis (percutaneous drainage of pericardial effusion).4 If the surgical management of the aortic dissection is not promptly available or the patient is too unstable to survive the transfer to surgery, pericardiocentesis and cont ...
... surgical drainage that should not be delayed in any way by pericardiocentesis (percutaneous drainage of pericardial effusion).4 If the surgical management of the aortic dissection is not promptly available or the patient is too unstable to survive the transfer to surgery, pericardiocentesis and cont ...
EFFECTS OF EXERCISE TRAINING ON MAXIMAL OXYGEN
... myocarditis, heart valve rupture or arrhythmia (Remes 2000, Vuori & Kesäniemi 2005) but also sudden physical effort may cause acute heart failure and even death (Vuori & Kesäniemi 2005). Chronical heart failure can begin in an acute event, but usually symptoms are developed and worsened gradually (R ...
... myocarditis, heart valve rupture or arrhythmia (Remes 2000, Vuori & Kesäniemi 2005) but also sudden physical effort may cause acute heart failure and even death (Vuori & Kesäniemi 2005). Chronical heart failure can begin in an acute event, but usually symptoms are developed and worsened gradually (R ...
Prosthesis patient mismatch in aortic valve replacement: possible
... consecutive AVR patients, the 30-day mortality was 4.6% in the 62% of patients without PPM, but was doubled with moderate PPM and increased 11-fold with severe PPM. Although patients with moderate and severe PPM had significantly more risk factors including impaired left ventricular function, older a ...
... consecutive AVR patients, the 30-day mortality was 4.6% in the 62% of patients without PPM, but was doubled with moderate PPM and increased 11-fold with severe PPM. Although patients with moderate and severe PPM had significantly more risk factors including impaired left ventricular function, older a ...
Pak Heart J - Pakistan Heart Journal
... adjacent to the sternum, a long axis view of the heart was obtained which included both aortic and mitral valves, the aortic root, sinuses of valsalva, sinotubular junction, and proximal 3 to 4cm of the ascending aorta .The left ventricular septum and posterior wall were seen at the base and midvent ...
... adjacent to the sternum, a long axis view of the heart was obtained which included both aortic and mitral valves, the aortic root, sinuses of valsalva, sinotubular junction, and proximal 3 to 4cm of the ascending aorta .The left ventricular septum and posterior wall were seen at the base and midvent ...
Analysis of left ventricular diastolic function using magnetic
... coronary disease. In an acute myocardial infarction there are anomalies of the myocardial metabolism, of ATP consumption and calcium transportation in the myocyte, all causing a delay in contraction.13,14 The influence of other factors that might be present in these patients such as the asynchronici ...
... coronary disease. In an acute myocardial infarction there are anomalies of the myocardial metabolism, of ATP consumption and calcium transportation in the myocyte, all causing a delay in contraction.13,14 The influence of other factors that might be present in these patients such as the asynchronici ...
Hyperhomocysteinemia alters sinoatrial and atrioventricular nodal
... 11. Immunohistochemical staining at murine AV node .................................................... 56 12. Immunohistochemical staining at murine AV node .................................................... 57 ...
... 11. Immunohistochemical staining at murine AV node .................................................... 56 12. Immunohistochemical staining at murine AV node .................................................... 57 ...
Slow and deep respiration suppresses steady
... been diverse findings about respiratory influences on steadystate sympathetic nerve activity. However, these studies included healthy or mildly hypertensive subjects with relatively lower sympathetic nerve activity at rest or during handgrip exercise or lower body negative pressure (8, 18). The magn ...
... been diverse findings about respiratory influences on steadystate sympathetic nerve activity. However, these studies included healthy or mildly hypertensive subjects with relatively lower sympathetic nerve activity at rest or during handgrip exercise or lower body negative pressure (8, 18). The magn ...
Cardiac contractility modulation
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Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.