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Evaluation And Treatment Of Common But Non
Evaluation And Treatment Of Common But Non

... Early beats with pause or non-conducted both lead to irregular heart rate Common in otherwise structurally and functionally normal hearts; rarely occur with underlying cardiomyopathy or atrial tumor PACs may be caused mechanically by central venous lines in the atria ...
Antiarrhythmic Effect of Nifekalant on Atrial Tachyarrhythmia in Four
Antiarrhythmic Effect of Nifekalant on Atrial Tachyarrhythmia in Four

... and prevention of atrial fibrillation or flutter concomitant with heart failure. We found that intravenous nifekalant changed atrial flutter or multifocal atrial tachycardia with a rapid atrial rate to atrial tachycardia of longer cycle length and caused termination in some cases. Pure K channel blo ...
Is Impedance Cardiography-Derived Systolic Time
Is Impedance Cardiography-Derived Systolic Time

... the EF category, two were from MUGA EF and three were from echo EF. ...
Quinidine for Pharmacological Cardioversion of Atrial Fibrillation: A
Quinidine for Pharmacological Cardioversion of Atrial Fibrillation: A

... In addition, parameters affecting the risk of proarrhythmia such as plasma potassium, QT interval, and LVEF were not used as inclusion or exclusion criteria in the studies17–22 of this metaanalysis,15 normal serum electrolytes were reported in only one trial,22 and digoxin was the only other antiarr ...
1 - Jordan University of Science and Technology
1 - Jordan University of Science and Technology

... 1. Describe divisions of the heart into four chambers and the internal and external features of each chamber. 2. Describe different parts of the conductive system of the heart and their arrangement and function within the myocardium. 3. Understand and descibe the principle of cardiac referred pain. ...
Reading the Holter ECG Report
Reading the Holter ECG Report

... The middle graph shows a series of 288 power graphs drawn each 5-minutes. It is called a 3D Power Graph. From left to right the frequency range is 0 to 50 Hz. The bottom 25% of the 3D shows mostly flat (low) power. And then you see lots of hills (more power) for the remaining 75%. The numbers and na ...
Syncope Update: Evaluation And Treatment
Syncope Update: Evaluation And Treatment

... ♦ Beware! Orthostatic hypotension is present in about 40% of patients over 70 years old. ♦ Up to 23% of patients younger than 60 have orthostatic blood pressure drops. ♦ If you are able to reproduce the patient’s symptoms on standing, this is helpful (regardless of the measurements).11 Diagnostic Te ...
chapter 13 defibrillators and cardioverters (draft)
chapter 13 defibrillators and cardioverters (draft)

... also widely accepted that the earlier defibrillation can be achieved, the better it is for the patient. Thus it was inevitable that implantable automatic defibrillators would be developed. These devices, similar in appearance to the implantable pacemaker, consist of a means of sensing cardiac defibr ...
PDF
PDF

... The exacerbation of central fatigue with reduced cerebral O2 delivery during whole-body exercise in healthy subjects has been recently demonstrated by Goodall et al. (2012). Endurancetrained cyclists exercised at ∼80% of their normoxic maximum power in both normoxia and hypoxia conditions. Exercise ...
Comparison of Enalapril Versus Captopril on Left Ventricular
Comparison of Enalapril Versus Captopril on Left Ventricular

... hours after acute myocardial infarction. Animal studies suggest additional benefits may be obtained with earlier initiation of angiotensinconverting enzyme (ACE) inhibitors. The effects on LV function of captopril and enalapril initiated within 24 hours of myocardial infarction were studied. Two hun ...
Right Ventricular Remodeling and Dysfunction With Subsequent
Right Ventricular Remodeling and Dysfunction With Subsequent

... Background Secondary tricuspid regurgitation (TR) as a result of pulmonary hypertension and/or left-sided heart disease is caused by tricuspid valve (TV) annular dilatation and tethering of the tricuspid leaflet after right ventricular (RV) dilatation. However, the mechanism of isolated TR without s ...
Biochemical markers of myocardial injury
Biochemical markers of myocardial injury

... The early appearance of a marker released into the bloodstream soon after an injury may facilitate early diagnosis. When developing assays it is important that they are sensitive, speci®c and have a short turnaround time, to allow results to be available within a clinically useful timeframe.10 These ...
total pulmonary venous drainage through a persistent left superior
total pulmonary venous drainage through a persistent left superior

... the right heart through a persistent left superior vena cava and the left innominate vein they were able to find accounts of only nine other patients, six of whom were babies diagnosed at autopsy. Another, although only diagnosed in life as having abnormal pulmonary venous drainage into the right su ...
Integrated analysis of atrioventricular interactions in - AJP
Integrated analysis of atrioventricular interactions in - AJP

... plex adaptive response of the RV to chronic overload in TOF have provided evidence that the RV cannot be seen as one entity. In addition, the impact of RV dysfunction on left ventricular (LV) and atrial function must be considered (1, 12, 15, 26). In 1974, Suga (25) highlighted the role of the atria ...
Complete atrioventricular block during central venous catheter
Complete atrioventricular block during central venous catheter

... intensive care units and on patients in monitored beds. Heart block and arrhythmia are known complications of central venous and pulmonary artery cardiac catheterization. Injury to the conducting system of the heart often involves the right bundle causing right bundle branch block (RBBB) and in pati ...
Left Ventricular Diastolic Function in Patients With
Left Ventricular Diastolic Function in Patients With

... Milwaukee, WI). Only cycles with ⬎ 70% of the maximal enddiastolic activity in the end-diastolic frame were included in the analysis. Lung background counts were subtracted from the time-activity curves representing each cardiac cycle. The background curves were then summed to create a single repres ...
NYHA III - Circulation: Heart Failure
NYHA III - Circulation: Heart Failure

... nd written informed consent was obtained d from all patients. The study consisted of 37 male patients d 70 years with CHF as a result of ische ischemic e heart disease or dilative cardiomyopathy y yopathy as assessed by cardiac catheterization. All patients hhad clinical signs IIIb a LV ejection fra ...
Low risk - The Cardiology Report
Low risk - The Cardiology Report

... in a similar clinical benefit to that achieved with warfarin in reducing the risk of ischemic stroke, but its superiority to warfarin was shown by a 21% overall reduction of stroke and thromboembolic events, which was secondary to a 50% reduction in hemorrhagic stroke.33 ...
His Bundle Electrocardiography
His Bundle Electrocardiography

... Downloaded from http://circ.ahajournals.org/ by guest on June 18, 2017 ...
UCSD DIVISION OF CARDIOVASCULAR MEDICINE
UCSD DIVISION OF CARDIOVASCULAR MEDICINE

... participate in as many cases and elective months as possible. The Advanced Heart Failure Service cares for a large (and growing) population of cardiomyopathy patients, and has a high volume of patients with ventricular assist devices and heart transplants. We perform 10-15 heart transplants and 30-4 ...
Morphologic demonstration of spontaneous and
Morphologic demonstration of spontaneous and

... *Secondary to operative damage of the left circumflex coronary artery at the time of mitral valve replacement for severe mitral regurgitation at age 32. ICD indicates implantable cardioverter defibrillator; VSD, ventricular septal defect; –, not available. ...
Triage strategy for urgent management of cardiac
Triage strategy for urgent management of cardiac

... surgical drainage that should not be delayed in any way by pericardiocentesis (percutaneous drainage of pericardial effusion).4 If the surgical management of the aortic dissection is not promptly available or the patient is too unstable to survive the transfer to surgery, pericardiocentesis and cont ...
Reliable Identification of “Truly Low” Thromboembolic Risk in
Reliable Identification of “Truly Low” Thromboembolic Risk in

... was defined by clinical symptoms (dyspnea and fatigue during exercise or at rest), signs of fluid retention on physical examination (pulmonary congestion or peripheral edema), or pulmonary congestion on chest radiography, followed by a comprehensive echocardiographic examination and other diagnostic ...
Improved Left Ventricular Structure and Function - diss.fu
Improved Left Ventricular Structure and Function - diss.fu

... In hypertensive (non-ESRD) patients under antihypertensive treatment a reduction in LV mass is directly linked to prognosis including lower rates of CV mortality, stroke, myocardial infarction, and all-cause mortality [27]. Improvement of LV systolic function (as determined by LVEF assessment) after ...
CHEST Recent Advances in Chest Medicine
CHEST Recent Advances in Chest Medicine

... ventricle also results in paradoxical motion of the septum. This is visualized as a bounce of the septum or movement of the septum toward the left ventricle during ventricular contraction. This paradoxical septal motion results from different rates of rise of intracavitary pressure during ventricula ...
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Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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