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Anterior tricuspid papillary muscle septalisation for
Anterior tricuspid papillary muscle septalisation for

... 1/ Population: Study period was from April 2011 to september 2012 Patients referred for tricuspid valve repair according to ESC guidelines ...
The Age-Associated Alterations in Late Diastolic Function in Mice
The Age-Associated Alterations in Late Diastolic Function in Mice

... with aging (Taffet et al., 1996), and this important measure of early diastolic filling was not improved in CR mice. In contrast, caloric restriction profoundly decreased peak A velocity, thus improving the E/A ratio. In humans, the altered filling of the left ventricle with age, as measured by E/A ...
An Integrated Framework for Cardiac Sounds Diagnosis
An Integrated Framework for Cardiac Sounds Diagnosis

... disease (CVDs) become one of the leading risk factors for global mortality in modern society. Fig.1 shows the proportion of non-communicable diseases (NCDs) deaths under the age of 70 years. Cardiovascular diseases are the largest proportion of NCD deaths (37%), followed by cancers and chronic respi ...
Alternate Sites of Permanent Cardiac Pacing: A Randomized Study
Alternate Sites of Permanent Cardiac Pacing: A Randomized Study

pub1211_25.08 - tarde.indd
pub1211_25.08 - tarde.indd

... the central fibrous body to form the penetrating bundle of His. At the boundary between the membranous and muscular parts of the interventricular septum, the AV bundle of His divided into the right (RBB) and left bundle branches (LBB). The RBB coursed downward in the muscular part of the interventri ...
Evaluation and Outcomes of Patients With Palpitations
Evaluation and Outcomes of Patients With Palpitations

... and analysis of variance tests to evaluate differences of presentation (P <0.002). The distribution of etibetween groups. Logistic regression analysis (BMDP ologies was not statistically different when those with LRa) was used to test for independence among pre- prior palpitations were compared to t ...
The Pathology of Acute Myocardial Infarction
The Pathology of Acute Myocardial Infarction

... Creatinine > 175µmol/l ...
and Hanjörg Just Stavros Konstantinides, Annette
and Hanjörg Just Stavros Konstantinides, Annette

... injection. Echo-contrast was considered to be adequate if the entire right atrium remained opacified for at least three cardiac cycles. The detection of five or more microbubbles in the left heart cavities within three cardiac cycles after their appearance in the right atrium was considered diagnost ...
Cardiology cases or, Murmurs for Dummies - OSCE-Aid
Cardiology cases or, Murmurs for Dummies - OSCE-Aid

... Surgical - cardiac resynchronisation therapy, left ventricular assist device (LVAD) or heart transplant ...
Cardiac myocytes` dynamic contractile behavior
Cardiac myocytes` dynamic contractile behavior

... Laske and Iaizzo, 2005). Right and left apex has been distinguished by increase of its surface area and relative cell alignment during heart looping (Manasek et al., 1972). Electromechanical coupling demonstrated that increased contraction force following an increase in stimulation frequency was sig ...
Heart Conditions and Treatment - Idaho Society of Health
Heart Conditions and Treatment - Idaho Society of Health

... • Pressure abnormality  Hypertension • Conduction abnormality  Arrhythmias • Structural abnormality  Heart Failure ...
Right Ventricular Geometry and Function in Pulmonary
Right Ventricular Geometry and Function in Pulmonary

Action of verapamil on sinus node, atrioventricular, and
Action of verapamil on sinus node, atrioventricular, and

... beta-blockers and atropine before verapamil adminis- found that increasing concentrations of verapamil tration. The Figure shows changes in stimulus-His increased the conduction velocity through the atria. Animal studies suggest that the action of verainterval during atrial paced rate at ioo/min. pa ...
Print - Circulation
Print - Circulation

... Patients. Thirty-six consecutive patients were studied. Informed consent was obtained from all. Six were excluded, four because the cardiac output or the pressure drop was not obtained as a result of problems experienced during catheterization, and two because they had significant aortic and mitral ...
cardiovascular disturbances caused by deficiency of vitamin b1
cardiovascular disturbances caused by deficiency of vitamin b1

... and of Keefer (1930) in China have been admirably extended by Soma Weiss and his colleagues ; in Boston cardiovascular disturbances, due probably to deficiency of vitamin B1, are not uncommon; they occurred in a ratio of about 1 in 160 admissions to the medical wards, and were more frequent than con ...
Pediatric Cardiology - Kuwait Institute for Medical Specialization
Pediatric Cardiology - Kuwait Institute for Medical Specialization

... consultation on all patients before a planned cardiac surgery. In addition, the trainee assesses all inpatients on a daily basis and documents encounters in the patient’s chart. He/she is rounds with the attending cardiologist and collaborates with other health care professionals involved in the car ...
Assessment of Mechanical Cardiac Function in Elite Athletes
Assessment of Mechanical Cardiac Function in Elite Athletes

... the 1940’s, 50’s and 60’s to record the ultra low frequency vibrations of the heart, thus allowing the measurement of the cardiac cycle events including timing, durations and amplitudes of contraction [25-28]. Later, the technology was refined by Salerno and colleagues to show that cardiac cycle tim ...
Paced right bundle branch block: where is the catheter
Paced right bundle branch block: where is the catheter

... catheter was inserted through the venous sheath and advanced 35 cm until ventricular pacing was achieved. The pacing catheter and venous sheath were secured via subcutaneous sutures. While an adequate heart rate with ventricular pacing was achieved, the temporary pacer was also causing diaphragmatic ...
light-weight shoes - OMICS International
light-weight shoes - OMICS International

... eccentric hypertrophy of the left and right ventricular wall in obesity may lead to malignant cardiac arrhythmias and sudden cardiac death. Many of these changes are reversible [20,21]. Alpert et al. and Alexander et al. showed that significant weight loss in extremely obese patients leads to favora ...
a comparative doppler-catheterization study of the left ventricular
a comparative doppler-catheterization study of the left ventricular

... period, the findings of this study indicate a trend that is comparable to other similar studies. This study also showed diastolic dysfunction and raised LVEDP more common in females than in males. Age, height, weight and body mass index (BMI) was not found to be associated with high LVEDP. Other stu ...
ABSTRACT Athletic performance tests the limits of the human body
ABSTRACT Athletic performance tests the limits of the human body

... while silent coronary artery disease is the main cause in athletes over 35 years.1 2 Given this distribution of underlying disease, we were puzzled by fi ndings in 46 high-level endurance athletes (performing ≥3×2 h of sports per week for more than 5 years; 80% competitive; 80% cyclists) that were re ...
Journal of Nippon Medical School Vol.77 No.5
Journal of Nippon Medical School Vol.77 No.5

... anthracycline dose; the correlation formula was y=0.051x + 42.2 (r=0.81, p<0.001). The cumulative anthracycline dose of 152.9 mg! m2, calculated from the correlation formula, was the cut-off for detection of electrophysiological cardiac abnormalities. Cardiac performance data at rest and dobutamine ...
Cardiac Volume in Normal Children and Adolescents
Cardiac Volume in Normal Children and Adolescents

... and Bay Area Heart Associations. Computation facilities provided by Grant 5-P07 FR-00024 from the National Institutes of Health were used in analyses of data. Circulation, Volume XXXV, March 1967 ...
A Comparison of the Acute Hemodynamic Effects of Inhaled
A Comparison of the Acute Hemodynamic Effects of Inhaled

... with experimentally induced PHT and Omar et al.18) in patients with PHT resulting from congenital cardiac defects. In this study we extended these findings to compare the effects of two agents; nitroglycerin and iloprost, the stable analogue of PGI2. This study corroborates our previous findings tha ...
Considerations for Exercise Testing & Prescription: Cardiac Population
Considerations for Exercise Testing & Prescription: Cardiac Population

... –  anginal & ischemic threshold by decreasing ...
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Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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