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clinical value of unipolar chest and limb leads
clinical value of unipolar chest and limb leads

... Chest leads were first employed in myocardial infarction by Wood and Wolferth in 1932. Before that time their use was limited to the elucidation of the auricular arrhythmias. The original lead IV was an antero-posterior lead since it was hoped that this would register changes in a plane at right ang ...
ACC/AHA/HRS 2008 Guidelines for Device
ACC/AHA/HRS 2008 Guidelines for Device

... for further description of the relationships with industry policy (1). See Appendix 1 for author relationships with industry and Appendix 2 for peer reviewer relationships with industry that are pertinent to this guideline. These practice guidelines are intended to assist health care providers in cl ...
Relation between Brain Natriuretic Peptide (BNP) and Congestive
Relation between Brain Natriuretic Peptide (BNP) and Congestive

... collect data from 75 patients with CHF and history of hypertension (case group), and 75 patients with history of hypertension only (control group). CHF subjects consisted of fourteen subjects with acute heart failure, and fifty six subjects with chronic heart failure. CHF group was also classified i ...
pdf 12 MB - Cardio Symposium 2011
pdf 12 MB - Cardio Symposium 2011

... heart failure would produce any benefits. Barr et al5 showed that spironolactone had beneficial cardiac effects (on sympathetic activity and on ventricular arrhythmias) when added to an ACE inhibitor in human heart failure. Aldosterone blockade was then shown clearly to reduce total mortality in bot ...
Electrocardiographic Recordings
Electrocardiographic Recordings

... heart rates.6 Accordingly, in the natural state, the QT interval is modified by heart rate per se and by autonomic tone. It has been shown that ,3-blockade with propranolol causes no significant changes in QT intervals when heart rate is held constant by pacing.18 If 3-blockade changes the normal re ...
Cardiac αVβ3 integrin expression following acute - Heart
Cardiac αVβ3 integrin expression following acute - Heart

... restoration of myocardial integrity.2 In some circumstances, maladaptive persistent processes may encourage remodelling and scarring to extend into the myocardium long after the initial causative injury. This may lead to progressive ventricular dilatation, ventricular dysfunction and heart failure. ...
ACC/AHA/HRS 2008 Guidelines for Device-Based Therapy of Cardiac Rhythm Abnormalities
ACC/AHA/HRS 2008 Guidelines for Device-Based Therapy of Cardiac Rhythm Abnormalities

... practice guidelines for important cardiovascular diseases and procedures, directs this effort. Writing committees are charged with the task of performing an assessment of the evidence and acting as an independent group of authors to develop, update, or revise written recommendations for clinical pra ...
ELEKTROCARDIOGRAFI LEARNING OUTCOME TINJAUAN TEORI
ELEKTROCARDIOGRAFI LEARNING OUTCOME TINJAUAN TEORI

... ST segment distinct from the T wave is usually absent. More often the ST-T wave is a smooth, continuous waveform beginning with the J-point (end of QRS), slowly rising to the peak of the T and followed by a rapid descent to the isoelectric baseline or the onset of the U wave. This gives rise to an a ...
the PDF - Heart Rhythm Society
the PDF - Heart Rhythm Society

... practice guidelines for important cardiovascular diseases and procedures, directs this effort. Writing committees are charged with the task of performing an assessment of the evidence and acting as an independent group of authors to develop, update, or revise written recommendations for clinical pra ...
sinus node dysfunction - Continuing Medical Education
sinus node dysfunction - Continuing Medical Education

... enter the surrounding atrial tissue. As with AV block, there are 3 degrees of block, but only 2° SA exit block can be diagnosed on the ECG with certainty, when a pause is noted which is a multiple of the preceding sinus cycle length, e.g. 2 X, 3 X, or 4 X as long. 1 degree SA block is not evident on ...
Advances in Cardiovascular Imaging
Advances in Cardiovascular Imaging

... (LVH) unexplained by abnormal loading conditions.1 The natural history varies from an asymptomatic course to drugrefractory angina/dyspnea, sudden cardiac death (SCD), and end-stage heart failure. The incidence of HCM-related SCD is approximately 1% to 2% in children and adolescents and 0.5% to 1% i ...
2012 ACCF/AHA/HRS Focused Update
2012 ACCF/AHA/HRS Focused Update

... Force. Each guideline is considered current unless it is updated, revised, or a published addendum declares it out of date and no longer official ACCF/AHA policy. Keeping pace with the stream of new data and evolving evidence on which guideline recommendations are based is an ongoing challenge to ti ...
original article
original article

... generalized congestion of viscera in all the 9 autopsy cases studied by them in Medical College, Trivandrum; they attributed the findings to generalized asphyxia; they offered hyperkalemia as the sole explanation for cardiac arrhythmias. The toxins block the Ca ions channels in cardiac muscles. Kini ...
Is redo percutaneous mitral balloon valvuloplasty (PMV) indicated in
Is redo percutaneous mitral balloon valvuloplasty (PMV) indicated in

... Informed consent was obtained and PMV was performed in a fasting state under local anesthesia and mild sedation. Percutaneous mitral balloon valvuloplasty was performed by the antegrade transseptal approach with the Inoue balloon technique in nine patients and the double-balloon technique in the oth ...
Ch08 - ISpatula
Ch08 - ISpatula

... the ____________, which pumps it to the lungs to be re-oxygenated. 4. The blood moves back to the heart through the ____________ and into the ____________, which pumps it out to the body. 5. Cessation of heart activity is called cardiac ____________________. 6. __________________ from within the hea ...
Exenatide infusion decreases atrial natriuretic peptide levels by
Exenatide infusion decreases atrial natriuretic peptide levels by

... levels were not directly associated with exenatide levels, but were related to the action of the decreased filling pressure during exenatide infusion. In our previous study, we demonstrated that exenatide infusion increased cardiac index as a result of chronotropy, without any changes in stroke volu ...
The Aging Heart - UMass Medical School
The Aging Heart - UMass Medical School

Valvular Heart Disease in Patients with Prolactinomas on
Valvular Heart Disease in Patients with Prolactinomas on

... Prolactinomas are pituitary adenomas that express and secrete prolactin (PRL) in varying degrees, almost invariably benign but often clinically significant [10]. They constitute 40% of all pituitary tumors [10-12]. Is the most frequent secreting pituitary tumor [11]. The estimated prevalence of clin ...
Four-dimensional ultrasonography of the fetal heart with
Four-dimensional ultrasonography of the fetal heart with

... Examination of the normal fetal heart The four-chamber view. Multiplanar slicing of a volume acquired with a transverse sweep of the fetal chest is depicted in Fig 1, A. The left upper panel shows the conventional four-chamber view, the right upper panel shows a sagittal section through the interven ...
The Fontan circulation: who controls cardiac output?
The Fontan circulation: who controls cardiac output?

... mechanism, but left ventricular filling is more important than myocardial contractility in augmenting stroke volume in normal individuals w3x. Clinicians have traditionally used this model to understand the changes of cardiac output in healthy and diseased hearts. This model works extremely well whe ...
Myocardium 2013
Myocardium 2013

... has a direct toxic effect on the myocardium Chronic alcoholism may be associated with thiamine deficiency, introducing an element of beriberi heart disease Adriamycin and Other Drugs Some of the chemotherapeutic agents doxorubicin (adriamycin) and daunorubicin are well recognized causes of toxic myo ...
Philips` kt BLAST enables one-breathhold global
Philips` kt BLAST enables one-breathhold global

... dramatically increased acquisition speeds. Preliminary results suggest that k-t BLAST’s data acquisition efficiency will permit a complete global function study in a single 20-second breath hold, versus multiple breath holds of 10-12 seconds each. ...
Cardiovascular Disease Prevention and Rehabilitation 2012
Cardiovascular Disease Prevention and Rehabilitation 2012

... achieve sustainable health outcomes for patients. These standards and core components support an integrated approach to the prevention and rehabilitation of cardiovascular disease as the foundation of every cardiac rehabilitation programme. The illustrative model of the seven core components represe ...
AED Resource Information
AED Resource Information

... situations and able to respond appropriately. • Hypothermia. People with hypothermia have been resuscitated even after prolonged exposure. If there is no normal breathing, begin CPR until an AED becomes available. Dry the patient’s chest and attach the AED. If a shock is indicated, deliver a shock a ...
Robert Kloner - Ischemic Conditioning Therapy
Robert Kloner - Ischemic Conditioning Therapy

... patients with acute myocardial infarction: a randomised trial. Lancet. 2010 Feb 27;375(9716):727. ...
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Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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