Improvement of left ventricular contractile function by
... function in patients with coronary artery disease, we studied 25 patients, 52 ± 2 years old (mean + SE), who completed a 12 month program of endurance exercise training and 14 additional patients with comparable maximal exercise capacities and ejection fractions who did not exercise. The training pr ...
... function in patients with coronary artery disease, we studied 25 patients, 52 ± 2 years old (mean + SE), who completed a 12 month program of endurance exercise training and 14 additional patients with comparable maximal exercise capacities and ejection fractions who did not exercise. The training pr ...
ecg made easy
... COLUMN III • R wave progression • Small to Tall COLUMN IV • R wave progression • Tall to Small ...
... COLUMN III • R wave progression • Small to Tall COLUMN IV • R wave progression • Tall to Small ...
DETERMINANTS OF CARDIAC FUNCTION: SIMULATION OF A
... HR while displaying time-dependent changes in pressure and volume in addition to a pressure-volume plot. It differs from previous models (1, 3, 5) by graphing these parameters on a beat-to-beat basis that is particularly useful when describing the dynamic adaptation of the pumping heart to various s ...
... HR while displaying time-dependent changes in pressure and volume in addition to a pressure-volume plot. It differs from previous models (1, 3, 5) by graphing these parameters on a beat-to-beat basis that is particularly useful when describing the dynamic adaptation of the pumping heart to various s ...
Use of procalcitonin for the diagnosis of pneumonia in patients
... The gold standards for the diagnoses were determined by two cardiologists who independently reviewed all medical records and classified the likely diagnosis as heart failure (HF), pneumonia, a combination of both, or another diagnosis. Both were blinded to the other’s ...
... The gold standards for the diagnoses were determined by two cardiologists who independently reviewed all medical records and classified the likely diagnosis as heart failure (HF), pneumonia, a combination of both, or another diagnosis. Both were blinded to the other’s ...
Hybrid Revascularization for Multivessel€Coronary Artery Disease
... OBJECTIVES The aim of this study was to assess the feasibility of hybrid coronary revascularization (HCR) in patients with multivessel coronary artery disease (MVCAD) referred for standard coronary artery bypass grafting (CABG). BACKGROUND Conventional CABG is still the treatment of choice in patien ...
... OBJECTIVES The aim of this study was to assess the feasibility of hybrid coronary revascularization (HCR) in patients with multivessel coronary artery disease (MVCAD) referred for standard coronary artery bypass grafting (CABG). BACKGROUND Conventional CABG is still the treatment of choice in patien ...
Discerning the Incidence of Symptomatic and Asymptomatic
... months before AF ablation and remained for a minimum of 18 months after ablation. The implantation and programming technique for the ICM was standardized across centers (described in the eMethods; http://www.jamainternalmed.com). The ICM data were downloaded at each visit to reduce the probability o ...
... months before AF ablation and remained for a minimum of 18 months after ablation. The implantation and programming technique for the ICM was standardized across centers (described in the eMethods; http://www.jamainternalmed.com). The ICM data were downloaded at each visit to reduce the probability o ...
Cardiorespiratory interactions and blood flow generation during
... porcine model of prolonged cardiac arrest (10 minutes). Infusion of 2 mL/kg in 10 minutes or 4 mL/kg in 20 minutes enhanced myocardial blood flow and cardiac index and significantly increased resuscitation success and survival rates [30•]. Hypertonic saline has been shown to be deleterious in hearts ...
... porcine model of prolonged cardiac arrest (10 minutes). Infusion of 2 mL/kg in 10 minutes or 4 mL/kg in 20 minutes enhanced myocardial blood flow and cardiac index and significantly increased resuscitation success and survival rates [30•]. Hypertonic saline has been shown to be deleterious in hearts ...
Aerobic Exercise Training Promotes Physiological Cardiac
... exercise training (20, 21, 24, 65, 89, 91) and confirmed by Ma et al. (58) and Martinelli et al. ...
... exercise training (20, 21, 24, 65, 89, 91) and confirmed by Ma et al. (58) and Martinelli et al. ...
Coronary flow regulation in patients with ischemic heart
... old and suffering from IHD were investigated. IHD was evidenced by severe effort-triggered angina pectoris and definite, typical electrocardiographic changes during a bicycle exercise test. Most of the patients had a history of myocardial infarction(s). They continued their medications as usual; mos ...
... old and suffering from IHD were investigated. IHD was evidenced by severe effort-triggered angina pectoris and definite, typical electrocardiographic changes during a bicycle exercise test. Most of the patients had a history of myocardial infarction(s). They continued their medications as usual; mos ...
... to provide benefits in several animal models of myocardial infarction (MI). However, its efficacy following MI initiation (as in clinical reality) remains to be tested. Therefore, this study investigated whether HO-1 over-expression, by cobalt protoporphyrin (CoPP) administered after LAD ligation, i ...
Low Ejection Fraction (16)
... • Fatigue—this happens because your muscles aren't getting enough oxygen from your blood. • Chronic cough—this is due to fluid buildup in the lungs. • Fluid retention—this happens especially in the legs and feet. In other cases a person might notice symptoms of dyssynchrony when they have a low EF: ...
... • Fatigue—this happens because your muscles aren't getting enough oxygen from your blood. • Chronic cough—this is due to fluid buildup in the lungs. • Fluid retention—this happens especially in the legs and feet. In other cases a person might notice symptoms of dyssynchrony when they have a low EF: ...
Research - Wiley Online Library
... For both clinical and non-clinical reasons, various strategies have been employed to improve physical performance through augmenting exercise with nutritional and/or hormonal supplements. The intent of these supplements is to increase muscle mass, endurance and power (Spriet & Gibala, 2004) above wh ...
... For both clinical and non-clinical reasons, various strategies have been employed to improve physical performance through augmenting exercise with nutritional and/or hormonal supplements. The intent of these supplements is to increase muscle mass, endurance and power (Spriet & Gibala, 2004) above wh ...
Valvular Heart Disease
... unsatisfactory echocardiograms. MRI and cardiac computed tomography may be useful to further evaluate the size of the aorta. Exercise testing is reasonable for assessment of functional capacity and symptomatic response in patients with a history of equivocal symptoms. Once the chronicity and stabili ...
... unsatisfactory echocardiograms. MRI and cardiac computed tomography may be useful to further evaluate the size of the aorta. Exercise testing is reasonable for assessment of functional capacity and symptomatic response in patients with a history of equivocal symptoms. Once the chronicity and stabili ...
A clinical approach to the assessment of left ventricular diastolic
... prolonged, there is a delay and prolongation of sarcomeric expansion. Additionally, in the case of regional ischaemia, there may be regional cellular impairment such that the heart ceases to function as a syncytium. Mechanical definition Mechanically, diastole is considered to begin when the pressur ...
... prolonged, there is a delay and prolongation of sarcomeric expansion. Additionally, in the case of regional ischaemia, there may be regional cellular impairment such that the heart ceases to function as a syncytium. Mechanical definition Mechanically, diastole is considered to begin when the pressur ...
2016 ACC/AHA/HFSA Focused Update on New Pharmacological
... to reduce morbidity and mortality. Angiotensin-converting enzyme (ACE) inhibitors reduce morbidity and mortality in heart failure with reduced ejection fraction (HFrEF). Randomized controlled trials (RCTs) clearly establish the benefits of ACE inhibition in patients with mild, moderate, or severe sy ...
... to reduce morbidity and mortality. Angiotensin-converting enzyme (ACE) inhibitors reduce morbidity and mortality in heart failure with reduced ejection fraction (HFrEF). Randomized controlled trials (RCTs) clearly establish the benefits of ACE inhibition in patients with mild, moderate, or severe sy ...
Biventricular and atrial diastolic function assessment using
... adults with Marfan syndrome (MFS). However, in the literature, data on right ventricular and bi-atrial diastolic function are limited. We aimed to investigate whether, in the absence of significant valvular disease, diastolic dysfunction is present not only in both ventricles but also in the atrial ...
... adults with Marfan syndrome (MFS). However, in the literature, data on right ventricular and bi-atrial diastolic function are limited. We aimed to investigate whether, in the absence of significant valvular disease, diastolic dysfunction is present not only in both ventricles but also in the atrial ...
Guidelines for the Prevention of Postoperative Atrial Fibrillation
... hemodynamic compromise, pulmonary edema, ventricular arrhythmias, and/or need for a permanent pacemaker. Although these complications are well recognized, the etiology is not as well defined. It is thought to be multifactorial and may be associated with any of the following: Hyperadrenergic state Pe ...
... hemodynamic compromise, pulmonary edema, ventricular arrhythmias, and/or need for a permanent pacemaker. Although these complications are well recognized, the etiology is not as well defined. It is thought to be multifactorial and may be associated with any of the following: Hyperadrenergic state Pe ...
Cardiac murmurs - Stiftung Tierärztliche Hochschule Hannover
... belong to the description of murmur intensities. The term precordial thrill (fremitus cardialis) is used for the focal buzzing sensation against the hand when palpating the cardiac area of a dog with a very strong cardiac murmur with its vibrations being transmitted even to the thoracic wall. These ...
... belong to the description of murmur intensities. The term precordial thrill (fremitus cardialis) is used for the focal buzzing sensation against the hand when palpating the cardiac area of a dog with a very strong cardiac murmur with its vibrations being transmitted even to the thoracic wall. These ...
Atrial antitachycardia pacing and managed ventricular pacing in
... pre-specified. The study was designed with a 3 arms randomization for two reasons: (i) the comparison between DDDRP + MVP and MVP allows to differentiate the impact of atrial pacing therapies from MVP, (ii) at the time of study design a pacing modality which minimizes unnecessary right ventricular p ...
... pre-specified. The study was designed with a 3 arms randomization for two reasons: (i) the comparison between DDDRP + MVP and MVP allows to differentiate the impact of atrial pacing therapies from MVP, (ii) at the time of study design a pacing modality which minimizes unnecessary right ventricular p ...
Tissier
... relaxation phase during pimobendan therapy or its normalization after cessation of the treatment. To our knowledge, this is the first study to report reversible mitral valve regurgitation, myocardial hypertrophy, and diastolic dysfunction in dogs under pimobendan treatment and in clinical conditions ...
... relaxation phase during pimobendan therapy or its normalization after cessation of the treatment. To our knowledge, this is the first study to report reversible mitral valve regurgitation, myocardial hypertrophy, and diastolic dysfunction in dogs under pimobendan treatment and in clinical conditions ...
A study on the prevalence of diastolic dysfunction in type 2 diabetes
... Around 75% of diabetic patients has been reported to die from cardiovascular pathology [3]. Echocardiography serves as an essential and excellent non-invasive diagnostic tool in assessing the structural and functional changes in the heart [4]. Several risk factors such as hyperglycemia, hyperlipidem ...
... Around 75% of diabetic patients has been reported to die from cardiovascular pathology [3]. Echocardiography serves as an essential and excellent non-invasive diagnostic tool in assessing the structural and functional changes in the heart [4]. Several risk factors such as hyperglycemia, hyperlipidem ...
Refractory hypertension and sleep apnoea: effect of CPAP on blood
... have blood pressure (BP) levels that are well controlled [1]. Hypertension in some of these patients persists despite multiple antihypertensive medications and excellent compliance [2]. In specialised hypertension clinics the prevalence of such refractory hypertension ranges 5–18% [3]. These patient ...
... have blood pressure (BP) levels that are well controlled [1]. Hypertension in some of these patients persists despite multiple antihypertensive medications and excellent compliance [2]. In specialised hypertension clinics the prevalence of such refractory hypertension ranges 5–18% [3]. These patient ...
IOSR Journal of Dental and Medical Sciences (IOSR-JDMS)
... and adverse outcomes of the three antifibrinolytic agents such as aprotinin, tranaxemic acid (TA) and epsilon amino caproic acid (EACA) in cardiac surgery. (4) The study results showed that all three antifibrinolytic agents significantly reduce blood loss after cardiac surgery. However, aprotinin wa ...
... and adverse outcomes of the three antifibrinolytic agents such as aprotinin, tranaxemic acid (TA) and epsilon amino caproic acid (EACA) in cardiac surgery. (4) The study results showed that all three antifibrinolytic agents significantly reduce blood loss after cardiac surgery. However, aprotinin wa ...
http://hyper.ahajournals.org/content/early/2013/07/08/ HYPERTENSIONAHA.113.01605.full.pdf
... protein (hs-CRP), and family history of CHD. Model 3 added physical activity level and AV nodal medication use. We then performed subgroup sensitivity analyses modeling the prevalence ratio regression of being in the least distensible quartile per SD change (7.9 bpm) in distensibility. In addition, ...
... protein (hs-CRP), and family history of CHD. Model 3 added physical activity level and AV nodal medication use. We then performed subgroup sensitivity analyses modeling the prevalence ratio regression of being in the least distensible quartile per SD change (7.9 bpm) in distensibility. In addition, ...
Starling`s law of the heart is explained by an intimate
... cells in which the sarcolemma has been mechanically removed have been interpreted to indicate that sarcoplasmic Ca 2 +- release mechanisms are indeed length dependent (2527). These studies appear to indicate that the Ca"" -induced release of Ca 2 + is acutely affected by length or the degree of stre ...
... cells in which the sarcolemma has been mechanically removed have been interpreted to indicate that sarcoplasmic Ca 2 +- release mechanisms are indeed length dependent (2527). These studies appear to indicate that the Ca"" -induced release of Ca 2 + is acutely affected by length or the degree of stre ...
Cardiac contractility modulation
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Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.