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Flash pulmonary oedema and bilateral renal artery stenosis: the Pickering Syndrome †
Flash pulmonary oedema and bilateral renal artery stenosis: the Pickering Syndrome †

... usually result in prompt resolution of FPO but may further compromise renal blood flow and function. This is particularly true with inhibitors of the renin–angiotensin–aldosterone system. Although empirically, renin–angiotensin–system inhibitors should prove to be very useful for emergency treatment ...
Cardiac Rhythm Management Devices (Part II)
Cardiac Rhythm Management Devices (Part II)

... are triggered pacing modes with fusion or pseudofusion beats. With both, pacing artifacts appear within surface electrocardiographic P waves or QRS complexes. With fusion, there is simultaneous myocardial activation by paced and spontaneous depolarizations. With pseudofusion, pacing stimuli do not p ...
Living with Heart Failure - Montefiore Medical Center
Living with Heart Failure - Montefiore Medical Center

... Take your medicines exactly as they are ordered. Do not self-adjust your medications. If you are having problems following the medicine schedule, or if you think you are having side effects, be sure to tell your heart failure provider. Bring your medicines and a copy of your medicine list with you t ...
Mechanism and significance of a decrease in ejection fraction
Mechanism and significance of a decrease in ejection fraction

... Data Systems A2 computer for data collection and subsequent analysis End-diastohc and end-systolic regions of interest were Identified us109 a sermautomated edge detection algorithm, ejection fraction was calculated from background corrected end-diastolic and end-systolic count measurements Wall mot ...
Cardiovascular Adaptations to Physical Training
Cardiovascular Adaptations to Physical Training

... could reflect ventdcular dilatation and be due simply to relative bradycardia, but left ventdcular posterior wall thickness did not change or increased slightly in most series, implying a true increase in muscle mass. Humanechocardiographic studies have been limited to providing data on left ventric ...
Involvement of mitogen-activated protein kinases and reactive
Involvement of mitogen-activated protein kinases and reactive

... It has been known for long time that cardiac glycosides including ouabain increase [Ca2+]i and contractility in cardiac myocytes by binding to the Na+/K+-ATPase [3–6]. In rat cardiac myocytes we showed that 10–100 µM ouabain caused about 20–50% inhibition of Na+/K+-ATPase in a dose-dependent manner ...
Outline for OHP CPR Macerato
Outline for OHP CPR Macerato

... 6. CPR is important in saving lives because after four to six minutes without the flow of oxygen blood, brain cells begin to die, then after 10 minutes brain death results. (Gordon). 7. Applying CPR can quickly save someone’s life. (Lawson, 65). 8. Cardiac arrest: the pumping action of the heart cau ...
clinical assessment of left ventricular diastolic function - Heart
clinical assessment of left ventricular diastolic function - Heart

... diastolic filling. The transverse dimension increases, the myocardium thins, and the atrioventricular (AV) ring retracts towards the left atrium. All these processes may be slowed in patients with left ventricular hypertrophy or diabetes, even when wall motion is coordinate, and such changes have be ...
Antiarrhythmic drugs for out-of-hospital cardiac arrest with
Antiarrhythmic drugs for out-of-hospital cardiac arrest with

... pVT. One retrospective study suggested that lidocaine may improve the success rate of resuscitation [10], contrary to the negative results reported in other studies [11, 12]. After the reports of two landmark studies on amiodarone [7, 13], resuscitation guidelines were revised with preference for am ...
Mechanisms With Clinical Implications for Atrial Fibrillation
Mechanisms With Clinical Implications for Atrial Fibrillation

... We excluded patients with dilated or hypertrophic cardiomyopathy, myocardial infarction, congenital heart disease, congestive heart failure, or valvular heart diseases and those receiving hemodialysis. AF patients were receiving standard therapy with antiarrhythmic drugs, b-blockers, angiotensinconv ...
AHA Scientific Statement
AHA Scientific Statement

... Heart failure (HF) may be defined as the inability of the heart to meet the demands of the tissues, which results in symptoms of fatigue or dyspnea on exertion progressing to dyspnea at rest. The inability to perform exercise without discomfort may be one of the first symptoms experienced by patient ...
S1936879816319100_mmc1
S1936879816319100_mmc1

... 3. Target lesion  24 mm in length by visual estimate (the intention was to cover the whole lesion with one stent of adequate length). 4. Protected left main lesion with >50% stenosis. 5. Target lesion stenosis  70% and < 100% by visual estimate. 6. Target lesion stenosis <70% who meet physiologica ...
Exercise in Diabetes Mellitus Patients – from the view
Exercise in Diabetes Mellitus Patients – from the view

... moderate and low levels of exercise Graded on relative scale (from 0 to 5) for eligibility – 0 to 1: indicating generally not advised or strongly discouraged – 4 to 5: indicating probably permitted – 2 to 3: indicating intermediate and to be assessed clinically in an ...
Assessment of Longitudinal Myocardial Stiffness Is Not - J
Assessment of Longitudinal Myocardial Stiffness Is Not - J

... diastolic component. This overlooking of the diastolic component was possibly because ventricular filling was considered a completely passive process that occurred only as a result of pressure gradients. In the 1960 s, the first studies of diastolic function appeared and from there the interest in t ...
anomalous pulmonary venous return with stenosis in
anomalous pulmonary venous return with stenosis in

... atrium or coronary sinus. The infracardiac connection (24%) can be through common vessel to the inferior vena cava, hepatic vein, portal vein, or gastric vein. The mixed type (4%) is a combination of two or three connections earlier described. In our cases vein collector was anomalous and crated an ...
Understanding Arrythmias
Understanding Arrythmias

... of your heart, at rates between 150 and 450 beats each minute. • Atrioventricular nodal re-entrant tachycardia (AVNRT) is the second most common SVT. In a normal heart, there is a single electrical pathway, or “gate”, called an atrioventricular node (AV node) that controls the timing and direction o ...
022802 Aortic Stenosis - New England Journal of Medicine
022802 Aortic Stenosis - New England Journal of Medicine

... Thus, the intervention required in adults, other than standard prophylactic antibiotics against infective endocarditis,8 is the replacement of the valve. The risks of replacing that valve must be weighed against the risks of delaying the procedure. The procedure can usually be delayed until symptoms ...
THE SUBSTITUTION OF A TETRAHEDRON FOR THE EINTHOVEN
THE SUBSTITUTION OF A TETRAHEDRON FOR THE EINTHOVEN

... to the adoption of the leads from the two arms and the left leg which are still in universal use. For a great many years little thought was given to the possibility that these leads might be entirely inadequate in certain respects and that great progress in electro~rdiographic diagnosis might be ach ...
A study in intracardiac conduction fusion with ventricular escape beats
A study in intracardiac conduction fusion with ventricular escape beats

... of the ventricles by both impulses results in normal or near-normal activation (see Fig. 3A). This normalization of the bundlebranch block pattern has been produced experimentally by fusion with end-diastolic ventricular extrasystoles (Bisteni et al., I960). The phenomenon has also been observed cli ...
Acute Exacerbation Impairs Right Ventricular Function in COPD
Acute Exacerbation Impairs Right Ventricular Function in COPD

... cases admitted to the outpatient clinics of the Pulmonary and Critical Care Department between October 2007 and December 2008. Thirty-three consecutive patients with acute COPD exacerbation were recruited into the study, after exclusion of patients with the following conditions: any clinical evidenc ...
Document
Document

... It is important in shock-refractory VF/VT to check the position and contact of the defibrillation pads. The duration of any individual resuscitation attempt is a matter of clinical judgement, and should take into account the perceived prospect of a successful outcome. If it was considered appropriat ...
Mitral Valve Prolapse
Mitral Valve Prolapse

... MVP are a midsystolic click followed by a mid to late systolic murmur. The click results from the sudden tensing of the mitral valve apparatus as the leaflets prolapse into the left atrium during systole. A medium to high-pitched murmur that is loudest at the apex represents turbulence of regurgitan ...
Medical treatment in Poland – analysis and models Cardiology
Medical treatment in Poland – analysis and models Cardiology

... because it was necessary to identify the patients, from the set under examination, who could have been registered in the public payer system for the first time since 2009, but who were not deemed to be newly diagnosed cases. On the basis of the analyses it was determined that in 2013 the incidence o ...
Attenuation of the Negative Inotropic Effects of Metoprolol at
Attenuation of the Negative Inotropic Effects of Metoprolol at

... acute hemodynamic collapse, despite these agents being well tolerated in sinus rhythm (1,2). Changes in heart rate may thus unmask negative inotropic effects of cardioactive drugs not apparent at rest, which may contribute to increased mortality during treatment with such agents in patients with imp ...
PowerPoint
PowerPoint

... ANSWER: Excellent question. You are not alone in your interest for patient follow up. The bottom line is that the Base Hospital is unable to implement a system such as you describe: we wish we could! Not only are paramedics not privy to this type of information which could be valuable on a number of ...
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Cardiac contractility modulation



Cardiac contractility modulation (CCM) is a treatment for patients with moderate to severe left ventricular systolic heart failure (NYHA class II–IV). The short- and long-term use of this therapy enhances both the strength of ventricular contraction and the heart’s pumping capacity. The CCM mechanism is based on stimulation of the cardiac muscle by non-excitatory electrical signals (NES). CCM treatment is delivered by a pacemaker-like device that applies the NES, adjusted to and synchronized with the electrical action in the cardiac cycle.In CCM therapy, electrical stimulation is applied to the cardiac muscle during the absolute refractory period. In this phase of the cardiac cycle, electrical signals cannot trigger new cardiac muscle contractions, hence this type of stimulation is known as a non-excitatory stimulation. However, the electrical CCM signals increase the influx of calcium ions into the cardiac muscle cells (cardiomyocytes). In contrast to other electrical stimulation treatments for heart failure, such as pacemaker therapy or implantable cardioverter defibrillators (ICD), CCM does not affect the cardiac rhythm directly. Rather, the aim is to enhance the heart’s natural contraction (the native cardiac contractility) sustainably over long periods of time. Furthermore, unlike most interventions that increase cardiac contractility, CCM is not associated with an unfavorable increase in oxygen demand by the heart (measured in terms of Myocardial Oxygen Consumption or MVO2). This may be explained by the beneficial effect CCM has in improving cardiac efficiency. A meta-analysis in 2014 and an overview of device-based treatment options in heart failure in 2013 concluded that CCM treatment is safe, that it is generally beneficial to patients and that CCM treatment increases the exercise tolerance (ET) and quality of life (QoL) of patients. Furthermore, preliminary long-term survival data shows that CCM is associated with lower long-term mortality in heart failure patients when compared with expected rates among similar patients not treated with CCM.
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