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Red blood cells
Red blood cells

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Solid Tumour Section Head and neck: Laryngeal tumors: an overview
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localization of histone gene transcripts in newt lampbrush
localization of histone gene transcripts in newt lampbrush

... are now pipetted on to a preparation of lampbrush chromosomes, and covered with an acidwashed 13-mm square coverslip. Three such covered preparations are placed in a square plastic dish, propped up on 2 L-shaped glass rods, with a pad of absorbent paper below liberally wetted with 20 x SSC, and the ...
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... was observed between the first 50 ns and the rest of the trajectory. During the first 50 ns, the first two peaks of the nucleosome-sodium RDF showed a subtle shift of some sodium from the second peak to the first. We did not observe any significant changes in nucleosomeion RDFs after the first 50 ns ...
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Chromatin Signature Identifies Monoallelic Gene Expression Across
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Regulation of 6sg expression site transcription and switching in

... the silencing of other ESs. We are currently exploring testable predictions of this hypothesis. If it were true, all manner of situations that interfered with efficient transcription of the currently active ES might cause an ES switch, including the insertion of transcription attenuators or other gr ...
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Epigenetics in stem-cell differentiation

Embryonic stem cells are capable of self-renewing and differentiating to the desired fate depending on its position within the body. Stem cell homeostasis is maintained through epigenetic mechanisms that are highly dynamic in regulating the chromatin structure as well as specific gene transcription programs. Epigenetics has been used to refer to changes in gene expression, which are heritable through modifications not affecting the DNA sequence.The mammalian epigenome undergoes global remodeling during early stem cell development that requires commitment of cells to be restricted to the desired lineage. There has been multiple evidence suggesting that the maintenance of the lineage commitment of stem cells are controlled by epigenetic mechanisms such as DNA methylation, histone modifications and regulation of ATP-dependent remolding of chromatin structure. Based on the histone code hypothesis, distinct covalent histone modifications can lead to functionally distinct chromatin structures that influence the fate of the cell.This regulation of chromatin through epigenetic modifications is a molecular mechanism that will determine whether the cell will continue to differentiate into the desired fate. A research study performed by Lee et al. examined the effects of epigenetic modifications on the chromatin structure and the modulation of these epigenetic markers during stem cell differentiation through in vitro differentiation of murine embryonic stem (ES) cells.
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