Aus dem Max-Planck-Institut für Psychiatrie
... biochemistry to global behavior. In mice and men, the sympathetic nervous system and the hypothalamic-pituitary-adrenocortical (HPA) system are the central regulators of the stress response (de Kloet et al., 2005). The HPA axis is formed by three main structures: the hypothalamus, the pituitary and ...
... biochemistry to global behavior. In mice and men, the sympathetic nervous system and the hypothalamic-pituitary-adrenocortical (HPA) system are the central regulators of the stress response (de Kloet et al., 2005). The HPA axis is formed by three main structures: the hypothalamus, the pituitary and ...
- Wiley Online Library
... genes have been identified, which are expressed specifically at distinct phases of vascular tissue differentiation or in a subset of vascular tissue cell types (Hertzberg et al., 2001; Kuriyama and Fukuda, 2001; Zhao et al., 2000). The subsequent functional analysis of such genes and mutants display ...
... genes have been identified, which are expressed specifically at distinct phases of vascular tissue differentiation or in a subset of vascular tissue cell types (Hertzberg et al., 2001; Kuriyama and Fukuda, 2001; Zhao et al., 2000). The subsequent functional analysis of such genes and mutants display ...
Answer Key to Problem Set 5
... natural selection have reduced its frequency in the human population? ...
... natural selection have reduced its frequency in the human population? ...
Genetic and experimental studies on a pigment
... these conditions, it was also clear that P^/P^ xanthophores and iridophores were less intensely pigmented than their wild-type neighbors. Ultrastructural studies will be necessary to further clarify the nature of these differences. Bagnara et al. (1979) have suggested that melanophores, xanthophores ...
... these conditions, it was also clear that P^/P^ xanthophores and iridophores were less intensely pigmented than their wild-type neighbors. Ultrastructural studies will be necessary to further clarify the nature of these differences. Bagnara et al. (1979) have suggested that melanophores, xanthophores ...
"Vectors in Gene Therapy". In: An Introduction to Molecular Medicine
... Retroviruses are comprised of two copies of a positive single-stranded RNA genome of 7 to 10 kb. Their RNA genome is copied into double-stranded DNA, which integrates into the host cell chromosome and is stably maintained. A property that allowed for the initial isolation was the rapid induction of ...
... Retroviruses are comprised of two copies of a positive single-stranded RNA genome of 7 to 10 kb. Their RNA genome is copied into double-stranded DNA, which integrates into the host cell chromosome and is stably maintained. A property that allowed for the initial isolation was the rapid induction of ...
Profile of Edward M. De Robertis - Howard Hughes Medical Institute
... Hamburger, sparked discussion in the club about the possibility of isolating genes involved in embryonic induction. In 1924, Spemann and a colleague had shown that a region of the amphibian embryo was able to induce the formation of Siamese twins after transplantation into another embryo (7). The ce ...
... Hamburger, sparked discussion in the club about the possibility of isolating genes involved in embryonic induction. In 1924, Spemann and a colleague had shown that a region of the amphibian embryo was able to induce the formation of Siamese twins after transplantation into another embryo (7). The ce ...
PDF
... However, a shift in orientation of vertical cell walls in the two tiers is frequently observed (data not shown). The elaboration of the final pattern of columella cells ‘4 surrounded by 8’ is completed at the torpedo stage either by periclinal/anticlinal or by tangential divisions (Fig. 1R,W). A sum ...
... However, a shift in orientation of vertical cell walls in the two tiers is frequently observed (data not shown). The elaboration of the final pattern of columella cells ‘4 surrounded by 8’ is completed at the torpedo stage either by periclinal/anticlinal or by tangential divisions (Fig. 1R,W). A sum ...
The Effect of Chromosomal Position on the Expression of the
... strains was normal. Each line exhibited a characteristic level of adult XDH-specific activity. The majority of these values were close to wild-type levels; however, the total variation in specific activity among the lines was nearly fivefold. Thus position effects influence expression of the rosy ge ...
... strains was normal. Each line exhibited a characteristic level of adult XDH-specific activity. The majority of these values were close to wild-type levels; however, the total variation in specific activity among the lines was nearly fivefold. Thus position effects influence expression of the rosy ge ...
Garrett-Engele* C. M., Siegal*, M. L., Manoli, D. S., Williams, B. C., Li. H., and Baker, B. S.
... Comparisons of the phenotypes of her, dsx double mutant flies with those of flies that are mutant at just one of these genes showed that her and dsx act independently to regulate some aspects of sexual differentiation and function interdependently to control other aspects of sexual differentiation i ...
... Comparisons of the phenotypes of her, dsx double mutant flies with those of flies that are mutant at just one of these genes showed that her and dsx act independently to regulate some aspects of sexual differentiation and function interdependently to control other aspects of sexual differentiation i ...
Tissue- and Development-specific Expression of Multiple
... nine to L-citrulline. Three isoforms of NOS encoded by distinct genes have been identified. The neuronal and endothelial NO synthases (nNOS, eNOS) are calcium/calmodulin dependent; their expression has in the past been viewed as constitutive (1–4). In contrast, the inducible isoform (iNOS) isolated ...
... nine to L-citrulline. Three isoforms of NOS encoded by distinct genes have been identified. The neuronal and endothelial NO synthases (nNOS, eNOS) are calcium/calmodulin dependent; their expression has in the past been viewed as constitutive (1–4). In contrast, the inducible isoform (iNOS) isolated ...
- eScholarship@UMMS - University of Massachusetts
... fibroblast cell lines were used in this study: an HGPS patient fibroblast (HGPS), a normal cell line from the father of the HGPS patient (Father), and an age-matched normal fibroblast line (Age Control). Two biological replicates were performed at different passages, since some changes in HGPS may p ...
... fibroblast cell lines were used in this study: an HGPS patient fibroblast (HGPS), a normal cell line from the father of the HGPS patient (Father), and an age-matched normal fibroblast line (Age Control). Two biological replicates were performed at different passages, since some changes in HGPS may p ...
Robust methods for purification of histones from cultured
... Post-translational modifications (PTMs) of histones play a role in modifying chromatin structure for DNA-templated processes in the eukaryotic nucleus, such as transcription, replication, recombination and repair; thus, histone PTMs are considered major players in the epigenetic control of these pro ...
... Post-translational modifications (PTMs) of histones play a role in modifying chromatin structure for DNA-templated processes in the eukaryotic nucleus, such as transcription, replication, recombination and repair; thus, histone PTMs are considered major players in the epigenetic control of these pro ...
Identification of Genetic and Epigenetic Risk Factors for Psoriasis
... indicating that other genetic effects and environmental triggers are important. In order to identify novel susceptibility genes of PS and PsA, I performed the first large scale genome wide association scan for psoriasis susceptibility loci using 233 cases and 519 controls. It revealed that genes of ...
... indicating that other genetic effects and environmental triggers are important. In order to identify novel susceptibility genes of PS and PsA, I performed the first large scale genome wide association scan for psoriasis susceptibility loci using 233 cases and 519 controls. It revealed that genes of ...
Supplemental Information
... promote vulval fates by causing osmotic stress Since CAN axons travel close to the excretory cell canals that regulate osmotic balance [1], and because CAN laser ablation causes a lethal fluid-filled phenotype resembling ablation of components of the excretory system [1,2], we tested if abnormalitie ...
... promote vulval fates by causing osmotic stress Since CAN axons travel close to the excretory cell canals that regulate osmotic balance [1], and because CAN laser ablation causes a lethal fluid-filled phenotype resembling ablation of components of the excretory system [1,2], we tested if abnormalitie ...
Drug-specific Sites of Topoisomerase II DNA
... observed in vivo (16). Nevertheless, others groups have described differences in cleavage patterns in viral (20), episomal (21), and cellular chromatin (22) following cell treatments with structurally unrelated inhibitors, mAMSA and VM-26, suggesting that the in vivo site selectivity is determined, ...
... observed in vivo (16). Nevertheless, others groups have described differences in cleavage patterns in viral (20), episomal (21), and cellular chromatin (22) following cell treatments with structurally unrelated inhibitors, mAMSA and VM-26, suggesting that the in vivo site selectivity is determined, ...
BSC Yeast Genetics I
... produces the mating pheromone “a” which it secretes outside the cell. This Mat a pheromone is detected by another haploid yeast cell that is the opposite mating type, i.e. a Mat α cell. This also happens in the opposite direction with a Mat α cell producing its pheromone that is detected by a Mat a ...
... produces the mating pheromone “a” which it secretes outside the cell. This Mat a pheromone is detected by another haploid yeast cell that is the opposite mating type, i.e. a Mat α cell. This also happens in the opposite direction with a Mat α cell producing its pheromone that is detected by a Mat a ...
Tumor Suppressor Genes
... While cells having large numbers of nuclei are generally inviable, cells having only two nuclei are often viable and will proceed to grow. When they enter subsequently into mitosis, the two nuclear membranes break down, the two sets of chromosomes will flock to a single, common mitotic apparatus, an ...
... While cells having large numbers of nuclei are generally inviable, cells having only two nuclei are often viable and will proceed to grow. When they enter subsequently into mitosis, the two nuclear membranes break down, the two sets of chromosomes will flock to a single, common mitotic apparatus, an ...
Effects of adenovirus delivered Flt
... mice compared with littermate controls (nrf1flox/– and AlbCre;nrf1+/–). ...
... mice compared with littermate controls (nrf1flox/– and AlbCre;nrf1+/–). ...
PowerPoint Presentation - Ontologies for biological annotation
... • These ontologies are organised as a collection of related terms, constituting nodes in a graph – Gradually incorporating other logical axioms ...
... • These ontologies are organised as a collection of related terms, constituting nodes in a graph – Gradually incorporating other logical axioms ...
The ZYG-1 kinase, a mitotic and meiotic regulator of centriole
... centrioles are tightly associated with the reproductive capacity of the centrosome (Sluder and Rieder, 1985) and have been implicated in organizing the PCM into a discrete focus (Bobinnec et al., 1998). Surrounding the centrioles is the pericentriolar material or PCM, a complex and dynamic meshwork ...
... centrioles are tightly associated with the reproductive capacity of the centrosome (Sluder and Rieder, 1985) and have been implicated in organizing the PCM into a discrete focus (Bobinnec et al., 1998). Surrounding the centrioles is the pericentriolar material or PCM, a complex and dynamic meshwork ...
1 Heterogeneous lineage marker expression in naive
... as depicted schematically in Figure S12. Marker(-) cell populations are much slower to regenerate marker(+). Although at first it seems odd to expect that the usually small marker(-) subpopulations should rapidly regenerate the much larger marker(+) population, in fact, in this simple reversible sch ...
... as depicted schematically in Figure S12. Marker(-) cell populations are much slower to regenerate marker(+). Although at first it seems odd to expect that the usually small marker(-) subpopulations should rapidly regenerate the much larger marker(+) population, in fact, in this simple reversible sch ...
REVIEWS - The SHINE Library
... remained unaffected. The Msx1 mutant mice developed hydrocephaly, and the interactions of Msx1 with Wnt1 and Pax6 are corroborated by similar hydrocephalic phenotypes in Wnt1sw/sw and Pax6sey/sey mice (27, 60). It is also possible that Msx1 may regulate genes that maintain homeostasis in the mature ...
... remained unaffected. The Msx1 mutant mice developed hydrocephaly, and the interactions of Msx1 with Wnt1 and Pax6 are corroborated by similar hydrocephalic phenotypes in Wnt1sw/sw and Pax6sey/sey mice (27, 60). It is also possible that Msx1 may regulate genes that maintain homeostasis in the mature ...
A Twist-like bHLH gene is a downstream factor of an
... 2002). In the present study, we use the term ‘mesenchyme’ for all of these cells, except where indicated otherwise. In addition to these three lineages of mesenchymal cells, ascidian larvae develop trunk ventral cells (TVCs), which are often regarded as a kind of mesenchymal cell because they give r ...
... 2002). In the present study, we use the term ‘mesenchyme’ for all of these cells, except where indicated otherwise. In addition to these three lineages of mesenchymal cells, ascidian larvae develop trunk ventral cells (TVCs), which are often regarded as a kind of mesenchymal cell because they give r ...