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BLOOD SYSTEM QUIZ May 2010 FORM: A Scantron Quiz -- Use #2 pencil. DO NOT MARK ON THIS QUIZ. Choose the best answer. 151. What is the approximate total blood volume of a healthy, fit, 20-year-old, 125 pound woman? A. 3 liters B. 5 liters C. 7 liters D. 9 liters 152. The hematocrit is the % volume of formed elements in centrifuged, unclotted blood. The centrifugation packs the formed elements and separates cells from plasma. The expected hematocrit for a healthy 25-year-old male would be A. 45 B. 55 C. 65 D. 75 153. What is NOT a major constituent of normal blood plasma? A. water and dissolved ions B. dissolved gases, nutrients and wastes C. albumin and other proteins D. hemoglobin, actin and myosin 154. What plasma protein is manufactured in the liver and plays a significant role in blood clotting? A. globulin B. albumin C. keratin D. fibrinogen 155. If the formed elements of blood in a normal, healthy person equals 100 %, what percentage represents red blood cells? A. 7 B. 70 C. 92 D. 99.9 Match the clinical term to its lay equivalent (everyday term): Clinical term Lay equivalent 156. erythrocyte A. platelets 157. leukocyte B. white blood cell 158. thrombocyte C. red blood cell 159. One hemoglobin molecule can transport up to _____ molecules of O2. A. 2 B. 4 C. 16 D. 32 160. Normal, healthy humans contain about 5 __________ red blood cells/mm3. A. thousand B. hundred thousand C. million D. billion 161. What is the most significant morphological difference between human white and red blood cells? A. White cells are larger, and unlike red cells, white cells contain nuclei and organelles. B. The nuclei of red cells are larger than the nuclei of white cells, but both contain organelles. C. The nuclei of white cells are larger than the nuclei of red cells, but both contain organelles. D. White cells are larger than red cells, and white cell nuclei are larger than red cell nuclei, but neither contains cytoplasmic organelles. Match the type of white blood cell to its description WBC Description 162. Lymphocyte A. granulocytic, phagocytize bacteria; 55-65 % circulating WBCs 163. Thrombocyte B. granulocytic, involved in responses to parasites and allergic reactions; 2-4 % circulating WBCs 164. Monocyte C. granulocytic, exaggerate inflammation at site of injury; less than 1 % circulating WBCs 165. Neutrophil D. agranulocytic, antigen presenting cells, form tissue macrophages; 2-8 % circulating WBC 166. Eosinophil E. agranulocytic, responsible for adaptive immunity; 20-30 % of circulating WBC 167. Basophil AB. Non-nucleated, membrane-bound fragment of megakaryocyte cytoplasm 168. Reaction of antibodies in serum or plasma with surface antigens on red blood cells to cause cell clumping is called A. autoimmune antibody complexing B. CD protein binding C. coagulation D. agglutination 169. The blood of someone with blood type B contains A. anti-B antibody only B. anti-A antibody only C. anti-A and anti-B antibodies D. neither anti-A nor anti-B antibody 170. The blood of someone with blood type AB contains A. anti-B antibody only B. anti-A antibody only C. anti-A and anti-B antibodies D. neither anti-A nor anti-B antibody 171. The blood of someone with blood type O contains A. anti-B antibody only B. anti-A antibody only C. anti-A and anti-B antibodies D. neither anti-A nor anti-B antibody 172. In the A-B-O blood system, the “universal donor” is blood type A. A B. B C. AB D. O 173. In the A-B-O blood system, the “universal recipient” is blood type A. A B. B C. AB D. O 174. Could a man with blood type AB father a child with blood type O? A. Yes B. No 175. Could a man with blood type B and mother with blood type A have a child with blood type O? A. Yes B. No 176. Could a man with blood group alleles AA and mother with blood group alleles BO have one child with blood type A and later child with blood group AB? A. Yes B. No 177. An Rh-negative mother first conceives a first Rh-positive daughter with an Rh-positive man. Next, she conceives an Rh-negative son with the same man. Later, she conceives a second Rh-positive daughter with the same man. As her obstetrician, which pregnancy do you consider “high risk” for erythroblastosis fetalis? A. The first daughter. B. The second daughter. C. The son. D. Both the son and second daughter are equally at risk. Match the blood disorder to its cause or description 178. Anemia 179. Polycythemia 180. Leukemia 181. Sickle cell disease A. B. C. D. Too many red blood cells Cancer suppressing certain white blood cells Caused by a point mutation in hemoglobin Too few red blood cells 182. What system is described as a parallel venous circulatory system composed of nodes, spleen, thymus gland and tonsils? It returns exudates and interstitial (intercellular) fluid to the general circulation, and 99 % of its cells are lymphocytes. A. The cardiovascular system. B. The immune system. C. The bone marrow. D. The lymphatic system. 183. What system is described as protecting the host from invasion by foreign agents, such as microorganisms, toxins, chemicals, drugs and cancer? A. The cardiovascular system. B. The immune system. C. The bone marrow. D. The lymphatic system. 184. What is NOT a synonym for innate immunity? A. specific B. non-specific C. inborn D. natural 185. Innate immunity does NOT consist of A. integument, secretions and mucous membranes. B. antibodies and cytotoxic lymphocytes. C. phagocytic antigen-presenting cells and natural killer cells. D. complement and other plasma proteins. 186. What is NOT a characteristic of adaptive immunity? A. non-specific B. distinguishes self from non-self C. memory D. TH lymphocyte-controlled 187. Which branch of the immune system operates within minutes or a few hours of antigen exposure? A. innate immunity B. adaptive immunity 188. Which branch of the immune system is commonly responsible for autoimmune disease? A. innate immunity B. adaptive immunity 189. Which immune cell mediates humoral immunity? A. T cells B. dendritic cells C. monocytes D. B cells 190. Which immune cell mediates cytotoxicity? A. T cells B. dendritic cells C. monocytes D. B cells 191. Cells carry an identity in the form of proteins that cover their plasma membranes. These proteins that define a cell as “self” are products of the A. Minor Homeostatic Control B. Minor Histocompatibility Complex B. Monocyte Hematopoietic Cells D. Major Histocompatibility Complex 192. Which proteins are found on certain “antigen presenting” cells in the immune response, such as B cells, macrophages, monocytes and dendritic cells)? A. MHC Class I B. MHC Class II C. MHC Class III D. CDs 193. T lymphocytes recognize antigen as very specific combinations of peptide fragments bound to MHC molecules. This phenomenon is known as A. B cell activation B. CD 4 T cell activation C. CD 8 T cell activation D. MHC restriction 194. Which cell produces antibodies? A. CD 4 T lymphocytes C. B lymphocytes B. CD 8 T lymphocytes D. dendritic cells 195. Cancer cells often do not express normal cell proteins. Which cell identifies and destroys cells based on what is absent from cancer cell surfaces? A. CD 4 T lymphocytes B. CD 8 T lymphocytes C. macrophages D. natural killer cells 196. Helper T lymphocytes express what protein on their cell surface that binds to MHC Class II molecules during antigen presentation? A. CD 2 B. CD 4 C. CD 8 D. β2-microglobulin 197. Cytotoxic T lymphocytes express what protein on their cell surface that binds to MHC Class I molecules during antigen presentation? A. CD 2 B. CD 4 C. CD 8 D. β2-microglobulin For questions # 48 – 50, use the following leukemia terms. No term is used more than once. One term will not be used. A. ALL B. AML C. CLL D. CML 198. The most common leukemia in young children; involves non-functional T cells and/or B cells. 189. This disease occurs almost exclusively in adults and has a 90% five-year survival rate with therapy; it can involve any blood cell type except lymphocytes. 190. A non-lymphocytic leukemia arising in adults; it can involve multiple cell types. BLOOD SYSTEM QUIZ May 2010 FORM: B Scantron Quiz -- Use #2 pencil. DO NOT MARK ON THIS QUIZ. Choose the best answer. 151. What is the approximate total blood volume of a healthy, fit, 20-year-old, 125 pound woman? A. 3 liters B. 5 liters C. 7 liters D. 9 liters 152. The hematocrit is the % volume of formed elements in centrifuged, unclotted blood. The centrifugation packs the formed elements and separates cells from plasma. The expected hematocrit for a healthy 25-year-old male would be A. 45 B. 55 C. 65 D. 75 153. What is NOT a major constituent of normal blood plasma? A. water and dissolved ions B. dissolved gases, nutrients and wastes C. albumin and other proteins D. hemoglobin, actin and myosin 154. What plasma protein is manufactured in the liver and plays a significant role in blood clotting? A. globulin B. albumin C. keratin D. fibrinogen 155. If the formed elements of blood in a normal, healthy person equals 100 %, what percentage represents red blood cells? A. 7 B. 70 C. 92 D. 99.9 Match the clinical term to its lay equivalent (everyday term): Clinical term Lay equivalent 156. erythrocyte A. platelets 157. leukocyte B. white blood cell 158. thrombocyte C. red blood cell 159. One hemoglobin molecule can transport up to _____ molecules of O2. A. 2 B. 4 C. 16 D. 32 160. Normal, healthy humans contain about 5 __________ red blood cells/mm3. A. thousand B. hundred thousand C. million D. billion 161. What is the most significant morphological difference between human white and red blood cells? A. White cells are larger, and unlike red cells, white cells contain nuclei and organelles. B. The nuclei of red cells are larger than the nuclei of white cells, but both contain organelles. C. The nuclei of white cells are larger than the nuclei of red cells, but both contain organelles. D. White cells are larger than red cells, and white cell nuclei are larger than red cell nuclei, but neither contains cytoplasmic organelles. Match the type of white blood cell to its description WBC Description 162. Lymphocyte A. granulocytic, phagocytize bacteria; 55-65 % circulating WBCs 163. Thrombocyte B. granulocytic, involved in responses to parasites and allergic reactions; 2-4 % circulating WBCs 164. Monocyte C. granulocytic, exaggerate inflammation at site of injury; less than 1 % circulating WBCs 165. Neutrophil D. agranulocytic, antigen presenting cells, form tissue macrophages; 2-8 % circulating WBC 166. Eosinophil E. agranulocytic, responsible for adaptive immunity; 20-30 % of circulating WBC 167. Basophil AB. Non-nucleated, membrane-bound fragment of megakaryocyte cytoplasm BLOOD SYSTEM QUIZ May 2010 FORM: C Scantron Quiz -- Use #2 pencil. DO NOT MARK ON THIS QUIZ. Choose the best answer. 151. What is the approximate total blood volume of a healthy, fit, 20-year-old, 125 pound woman? A. 3 liters B. 5 liters C. 7 liters D. 9 liters 152. The hematocrit is the % volume of formed elements in centrifuged, unclotted blood. The centrifugation packs the formed elements and separates cells from plasma. The expected hematocrit for a healthy 25-year-old male would be A. 45 B. 55 C. 65 D. 75 153. What is NOT a major constituent of normal blood plasma? A. water and dissolved ions B. dissolved gases, nutrients and wastes C. albumin and other proteins D. hemoglobin, actin and myosin 154. What plasma protein is manufactured in the liver and plays a significant role in blood clotting? A. globulin B. albumin C. keratin D. fibrinogen 155. If the formed elements of blood in a normal, healthy person equals 100 %, what percentage represents red blood cells? A. 7 B. 70 C. 92 D. 99.9 Match the clinical term to its lay equivalent (everyday term): Clinical term Lay equivalent 156. erythrocyte A. platelets 157. leukocyte B. white blood cell 158. thrombocyte C. red blood cell 159. One hemoglobin molecule can transport up to _____ molecules of O2. A. 2 B. 4 C. 16 D. 32 160. Normal, healthy humans contain about 5 __________ red blood cells/mm3. A. thousand B. hundred thousand C. million D. billion 161. What is the most significant morphological difference between human white and red blood cells? A. White cells are larger, and unlike red cells, white cells contain nuclei and organelles. B. The nuclei of red cells are larger than the nuclei of white cells, but both contain organelles. C. The nuclei of white cells are larger than the nuclei of red cells, but both contain organelles. D. White cells are larger than red cells, and white cell nuclei are larger than red cell nuclei, but neither contains cytoplasmic organelles. Match the type of white blood cell to its description WBC Description 162. Lymphocyte A. granulocytic, phagocytize bacteria; 55-65 % circulating WBCs 163. Thrombocyte B. granulocytic, involved in responses to parasites and allergic reactions; 2-4 % circulating WBCs 164. Monocyte C. granulocytic, exaggerate inflammation at site of injury; less than 1 % circulating WBCs 165. Neutrophil D. agranulocytic, antigen presenting cells, form tissue macrophages; 2-8 % circulating WBC 166. Eosinophil E. agranulocytic, responsible for adaptive immunity; 20-30 % of circulating WBC 167. Basophil AB. Non-nucleated, membrane-bound fragment of megakaryocyte cytoplasm