Download ch 10 Human GeneticsTest Qustions Study Guide

BSU Ch. 10 HUMAN Genetics Study Guide Test Questions
Write these answers on a separate paper.
1. Y/N Can a pedigree be used on each of the following to
a. Determine whether an allele is dominant or recessive.
b. Show how a trait is passed from one generation to the next.
c. Determine whether a trait is inherited.
2. In a pedigree, a circle represent a(an) female
3. Are alleles found on the same chromosomes are linked?
4. T/F Gene therapy is successful if viruses carrying the replacement gene infects the person’s cells
5. T/F The purpose of gene therapy is to cure genetic disorders
6. What percentage of human sperm cells carry an X chromosome?
7. T/F Many sex linked genes are located on the X chromosomes only
8. The failure of chromosomes to separate during meiosis is called
9. Which of the following would you be least likely to see in a pedigree?
a. About half of the symbols are circles
b. All of the symbols are unshaded
c. All of the symbols are half-shaded
d. All of the symbols are shaded
10. Some gametes may have an extra copy of some genes if nondisjunction occurs during meiosis
11. Is PKU caused by a dominant allele? PKU? Huntington’s?
12. Which blood genotype also has the same phenotype?
13. Colorblindness is more common in males than in females due to
14. Human females produce egg cells that have what sex chromosome?
15. How would scientists TEST for alleles that cause human genetic disorders?
16. Sickle cell disease is caused by
17. What is the first step in gene therapy?
18. In cystic fibrosis, a change in a single gene causes the protein called CFTR to
19. Y/N: Can nondisjunction can involve Autosomes? Sex chromosomes? Homologous chromosomes?
20. The Human Genome Project is an attempt to do what?
21. Describe the hemoglobin of a person with sickle cell disease, compared with normal hemoglobin.
22. A cat that has spots of only one color can be (male/Female), while calico cats can only be (male/female).
23. T/F The human genome was sequenced by looking for overlapping regions between sequenced DNA fragments,
called shotgun.
24. Y/N: Huntington’s disease is caused by a recessive allele.
25. How many chromosomes are shown in a normal human karyotype?
26. Due to the X chromosome containing genes that are vital for normal development, no baby has been born
without what chromosome?
27. What can be observed in a karyotype?
28. Y/N: Are autosomes, sex chromosomes, and homologous chromosomes shown in a karyotype?
29. What conclusion CANNOT be made from two DNA fingerprints that show identical patterns of bands?
30. What did the sequence of human chromosomes 21 and 22 show?
31. If a man with blood type A and a woman with blood type B produce an offspring, what might be the offspring’s
blood type?
32. Is ABO blood group determined by multiple alleles? PKU? Huntington’s disease?
33. Why are people who are heterozygous for sickle cell disease generally healthy?
34. Does a human female inherit one copy of every gene located on EACH of the X chromosomes or not?
35. Does a person who has PKU inherit the recessive allele for the trait from one parent or both?
36. T/F The father of a colorblind boy may be colorblind?
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What sex chromosome(s) does a male have?
Does point mutation lead to cystic fibrosis?
What combination of sex chromosomes represents a normal female?
What is the approximate probability that a human offspring will be a female?
Y/N: Is the process of DNA fingerprinting based on no two people, except identical twins, having exactly the
same DNA?
Y/N: Can an allele that is dominant or recessive be obtained from the Human Genome Project?
Y/N: By looking at the parents and the offspring of an individual, can you tell if they are a carrier for a trait?
Is a person who has Klinefelter’s syndrome considered to be a male?
What is the probability that a son with a dad who does not have hemophilia and a mom who is a carrier of the
disorder will have hemophilia?
Why are all X-linked alleles expressed in males, even if they are recessive?
What is a carrier?
How is the DNA sequence of the allele that causes cystic fibrosis different from that of a normal allele?
If malaria were eliminated from a certain area, how would the frequency of the sickle cell allele in that area
change?
Y/N: Is AB blood called the universal recipient?
T/F Individual 2 in Figure 14-2 heterozygous for free earlobes?
Predict the genotype and phenotype of individual 14 in Figure 14-2.
In Figure 14-2, how many children of individuals of 4 and 5 have attached earlobes?
In Figure 14-2, are any of the descendants of individuals 1 and 2 homozygous for free earlobes?
Can you be certain of the genotype of individual 5 in Figure 14-2?
T/F Slide 4 in Figure 14-3 shows blood that contains no antigens?
Which numbered slide in Figure 14-3 shows type B blood?
In Figure 14-3, what is the genotype(s) of the person whose blood is shown in slide 1?
Which of the slides in Figure 14-3 shows the blood of a person who can safely receive any type of blood in a
transfusion? Identify the person’s blood type.
Y/N: Are chromosomes 1-22 in Figure 14-1 autosomes?
How many chromosomes are shown in the human karyotype in Figure 14-1?
Identify the sex chromosomes in Figure 14-1.
Y/N: Are the chromosomes in each numbered group in the human karyotype in Figure 14-1 homologous
chromosomes?
Are the chromosomes that make up each numbered pair similar on the sex chromosomes or based on size?
14.3
14.2
14.1
14.2