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Nervous System Review A. The nervous system can be split into the CNS and the ____________________. The CNS contains the ____________________ and the ____________________. The peripheral nervous system, which contains the peripheral nerves, can be split into two main divisions, ____________________ and ____________________. The former of these can be further divided into the ____________________, which receives sensory information from external stimuli, and the ____________________, which monitors the internal environment. The latter contains subdivisions of its visceral component. The ____________________ component rises the body for action, while the ____________________ has a calming effect. The neuron is made up of the body, called the ____________________, the ____________________ , which receive incoming signals, and the ____________________ , which transmits outgoing signals. The axon itself is covered with ____________________ gated channels, which allow ____________________ to come in, and ____________________ to exit. The end of the axon is characterized by the ____________________ knob, which has voltage gated channels which allow ____________________ to enter. The influx of this ion into the synaptic knob causes a release of chemicals called ____________________. A post-synaptic potential is triggered when these chemicals diffuse across the ____________________ , and bind to ____________________ gated channels, which allow either ____________________, ____________________ or ____________________ to enter or leave the cell. B. Name the location and discuss the function of the following: Oligodendrites – Ependymal cells – Microglia – Ascrocytes – Schwann cells – 1. What kind of summation is evident at A and will there be an action potential at the hillock? 2. How does the potential travel down the soma? 3. Describe the channels located at each of the sections, how they are gated, what ions go in what direction, and the effect of their concentration change inside the neuron. 4. Summarize signal propagation. Muscle Review A. Skeletal muscle is characterized by may ____________________, and ____________________ (an alternating stripe pattern under microscope). It is under ____________________ control. The functional unit of muscle is called a ____________________. The ER of muscle cells is called the ____________________. A ____________________ unit is comprised of one ____________________ and all the muscle fibers in innervates. The major neurotransmitter involved in muscle contraction is ____________________. The two filament types are ____________________, the thin filament, and ____________________, the ____________________thick filament. ____________________ muscles is dark red in color, contains ____________________ levels of myoglobin, is ____________________ to fatigue and relies on ____________________ for energy. Fast glycolytic muscle is ____________________ in color, ____________________ to fatigue and relies on the ____________________ system as well as glycolysis for energy. B. Number the following in the order in which they occur during contraction and fill in either the stage name or description. ___ Excitation contraction coupling Action potential spreads down to T-tubules and triggers Ca, leakage, and then release. Ca binds to troponin, causing the tropomyosin to change shape and expose actin active sites ___ ___ Contraction Myosin heads hydrolyzes ATP to ratchet into open position ( \__ ), attaches to active sites on actin, kicks off ADP and P to bend back into relaxed position ( /__ ) and move along actin and binds ATP to release. ___ Label the following on the diagram: 1. A-band 2.I-band 3.Sarcomere 4.Z-disk 5.Actin 6.Myosin 7. H-band Cardiac Review A. The cardiovascular system is divided into a ____________________ circuit, serviced by the right heart, and the systemic circuit, serviced by the ____________________. The heart is innervated by the____________________ nervous system, specifically by the ____________________ nerves, which supply ____________________ stimulation to the ____________________nodes, as well as various sympathetic nerves. The cardiac rhythm is set by a pace maker called the ____________________ node, causing ____________________ systole. Signals from this area travel to the ____________________ node, causing ____________________ systole. Without external innervation, the SA node maintains heart rate at ____________________bpm, the AV node can maintain heart rate at ____________________ bpm, and lack of any pacemaker or nervous control will result in a ____________________ bpm rate maintained by other ectopic focci. ____________________ the volume of blood pumped by each ventricle in one minute, and is a product of ____________________ X ____________________. Heart rate is raised or lowered by positive and negative ____________________ factors. Stroke volume is determined by ____________________ , ____________________ and ____________________. Contractility is influenced by positive and negative ____________________ factors. B. Label the diagram and trace blood flow with arrows. C. Label the segments as P wave, T wave, PR interval, ST wave, QRS interval. Describe the events at the P wave QRS complex T wave