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Name ____________________________________ Class ______ Date _________________ CANCER Directions: Read the section “Cancer”. Go back and answer questions. 1. The title of this chapter is CANCER. Write about what you already know about Cancer. 2. Why is there a picture of a crab on page 64? 3. Describe the picture on page 65. 4. There is a wonderful diagram on pages 66 and 67. Describe what you see and read in that diagram? 5. This chapter is divided into two major sections. What are the two sections? 6. Before you read, what do you think the section entitled “What is Cancer?” about? 7. The other section of the chapter is “Treating and Preventing Cancer?”. What do you think this section is about? 8. How does the chapter answer the question what is Cancer? 9. How does cancer begin? 10. From the chapter, what does the word mutation mean? 11. How does the cell behave as a result of a mutation? 12. Use Figure 17 and describe the three steps how cancer spreads? 13. How does cancer spread from one part of the body to another part of the body? 14. How are cancer cells different from normal cells? 15. What is the relationship between cancer and DNA? 16. Identify three ways cancer is treated? 17. Which method of treating cancer is almost always a part of the treatment for small tumors that have not spread to other parts of the body? EXPLAIN why this method is chosen. Cell Division and DNA Please follow this page, clicking on the colored and underlined websites. Some of the answers will appear on the web page. Some answers you will need to figure out. FOLLOW ANY DIRECTIONS GIVEN ON THIS LAB SHEET. You do not have permission to visit other web sites during this lab. NO MUSIC! This is your Warning. 1. Click: http://www.classzone.com/books/ml_science_share/vis_sim/hbm05_pg87_skin/hbm05_pg87_skin.html Click go, go, next. What is this page showing you? __________________________________________ Describe what skin cells must do to fill the gap in the epidermis? ______________________________ Summarize what happened to the scrape: ________________________________________________ __________________________________________________________________________________ Draw 2 pictures of the scrape. One picture before it heals and one picture after it heals 2. http://learn.genetics.utah.edu/units/basics/cell/ Each person is made up of cells that do many different jobs. What type of cells did you observe in question #1? ____________________________________ Although the cells do different jobs, each cell contains similar parts called ___________________________. CLICK ON THE NUCLEUS The nucleus is referred to as the cell’s ______________________. Why is the nucleus called the cells brain? ____________________________________________________________________________ _________________________________________________________________________________ How is the information necessary to run the cell stored? ____________________________________ What keeps the DNA in the nucleus and separate from the other parts of the cell? ____________________________________________________ 3. http://www.cellsalive.com/mitosis.htm Push the F 11 key on your keyboard. Scroll down until you see the small box. Click the play button. Watch the cell in the small box. Play several times so you can clearly observe. What is happening to the cell? ____________________________________________________ If it helps to see this more clearly, use the step button. What began as a single cell, is now _____________________________________________Based on what you already know about the nucleus, do you think the new cell has the same number of chromosomes? _______________________ Now look at the center of the cell. What are the bundles that appear to separate? ___________________ On the right there are several stages of cell division. They are lined up from top to bottom in order. What is the first stage? _________________________________ Click on telophase and figure out how many chromosomes each of the two new cells will have. _____________________________________ Go back to prophase and count the number of chromosomes you see there. _____________________ The new cells will have 4 chromosomes. In order for that cell to divide into two, what must happen to the number of chromosomes? ________________________________ 4. http://serendip.brynmawr.edu/sci_edu/waldron/pdf/MitosisMeiosisProtocol.pdf Each of us began as a single cell, so one important question is: How did that single cell develop into a body with more than a trillion cells? _____________ ________________________________________________________________________ During cell division one cell turns into _________ and those two cells divide into _________ and those four cells divide into ______________. Your body continues to produce new cells through cell division. Think back to question #1. Why was cell division so important in this example? ________ _______________________________________________________________________________ When one cell divides into two, each cell is called a ____________________________________ Since it is important for each cell to contain the original number of chromosomes, how do you think each daughter cell gets a complete set of chromosomes? ________________________________ ______________________________________________________________________________ What is the process of cell division called? _______________________________________________ 5. http://www.teachersdomain.org/resources/tdc02/sci/life/stru/dnadivide/assets/tdc02_vid_dnadivide/tdc02 _vid_dnadivide_56_mov.html Once this begins to play pause it and turn the captions on. Mitosis splits cells into ______________________________________________________. Early in mitosis once the loose strands of DNA form chromosomes, each chromosome __________________________. What happens to the nuclear membrane? __________________________. Once the chromosomes lime up in the middle, what happens? _______________________________________________________________________ Once the chromosomes are pulled to either end of the cell, what happens? ________________________ ___________________________________________________________________________________ At the end of cell division, what happens to the nucleus of the new cells? __________________________________________________________________________________ What happens to the two cells? ________________________________________________________ 6. http://serendip.brynmawr.edu/sci_edu/waldron/pdf/MitosisMeiosisProtocol.pdf It is OK to OPEN. Go to page 2. Once the DNA of a chromosome has been ___________________, the two copies of the DNA form ______________________________ which are attached to each other at the ________________________________. These chromatids are often called sister chromatids because ______________________________________. During mitosis the two chromatids of a chromosome __________________________________________________________; one of these chromosomes goes __________________________________________________. Use the site from question #6 to help you label the following diagram: 7. http://highered.mcgrawhill.com/olcweb/cgi/pluginpop.cgi?it=swf::535::535::/sites/dl/free/0072437316/120073/bio14.swf::Mitosi s%20and%20Cytokinesis Press the F11 key. Please turn the audio off and the text on before you begin. Use the pause button frequently to stop the animation and record the information you need. Mitosis is a process _____________________________________________________________________ What are important things that happen during PROPHASE? _____________________________________ _____________________________________________________________________________________ Draw and label a diagram of the cell below, showing the chromosomes and spindle fibers during METAPHASE: Draw and label a diagram of the cell below, showing the chromosomes and spindle fibers during ANAPHASE: Draw and label a diagram below showing the chromosomes, nuclear membrane and cell membrane during TELOPHASE: 8. http://learn.genetics.utah.edu/units/basics/tour/ Click on What is DNA? The animation brings you into the _____________________________. NEXT. Does the nucleus of an ear cell contain just the necessary instructions that tell the ear cell how to operate? Answer in complete sentence: ___________________________________________________________________________________________ ____________________________________________________________________________ Next. Why is DNA referred to as a blueprint? ____________________________________________________ ________________________________________________________________________________________ Click on What is a Gene? Describe a gene. _____________________________________________________________________________________ NEXT: One strand of DNA contains ________________________________________. All of these genes are needed __________________________________________________________________________________operate all parts of our bodies. CLICK- What is a chromosome? Each cell contains DNA equal to about _______________________ long. How does it fit in a cell? _________________________________________________________________ Click NEXT until you find the next answer: How many chromosomes does one cell hold? _______________________________________________________________________________________ How many chromosomes in a human cell? __________________ Click NEXT to find: How many chromosomes does a mosquito have? __________ An onion? _________ A carp (fish)? ___________ CLICK What is Heredity? What exactly are our traits? ________________________________________ _____________________________________________________________________________________ ____________________________________________________________________________________ CLICK What is a Trait? What exactly is a trait? _____________________________________________ _____________________________________________________________________________________