Download Breast|Ovarian|Uterine26 gene list

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Transcript
Hereditary Cancer Testing
GENE LIST
Panel:
Breast|Ovarian|Uterine26
ATM
BRCA2
CHEK2
FANCC
MSH2
NBN
PMS2
RAD51C
TP53
BARD1
BRIP1
EPCAM
MLH1
MSH6
NF1
PTEN
RAD51D
XRCC2
BRCA1
CDH1
FAM175A
MRE11A
MUTYH
PALB2
RAD50
STK11
Approximately 5-10% of breast cancer1-2 and 20-25% of ovarian cancer3-4 is hereditary.
About 2-3% of uterine cancer5 is also hereditary. The majority are caused by several
high-risk genes, many of which overlap between these three types of cancer. Additional
moderate-risk genes are also known to play a role in women’s hereditary cancers.
Breast|Ovarian|Uterine26 is a genetic test that looks for changes in 26 genes known to
increase the risk for breast, ovarian, and/or uterine cancer.6-30
References available on the Human Genetics Laboratory website:
www.unmc.edu/mmi/geneticslab/resources/reference-articles.html
UNMC Human Genetics Laboratory where excellence is dominant | 402-559-5070 | www.unmc.edu/geneticslab