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Immune Response Immune System • Responsible for protecting the body from disease. • 3 lines of defense 1st Line of Defense • SKIN! • Acts as a barrier to invading pathogens. 2nd Line of Defense • Occurs when injured cells release chemicals that increase the blood flow to an invaded region. • The blood brings white blood cells that attack the pathogens. • Macrophage: a type of white blood cell that engulfs and kills pathogens. 3rd Line of Defense • Involves attacking specific pathogens. • Macrophages, T Cells, and B Cells attack and kill infected cells. Active Immunity • The body is exposed to a pathogen and produces antigens specific to that pathogen. • Person can be exposed accidentally or purposefully by vaccination. Passive Immunity • The antibodies are passed from one individual to another. • Usually through pregnancy.