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Chapter 17: Adaptive Immunity: Specific Defenses of the Host Antibodies Antigens Humoral Immunity Cellular Immunity Adaptive Immunity $100 $100 $100 $100 $100 $200 $200 $200 $200 $200 $300 $300 $300 $300 $300 $400 $400 $400 $400 $400 $500 $500 $500 $500 $500 FINAL ROUND © 2013 Pearson Education, Inc. Topic 1: Antibodies $100 Question How many classes of antibodies are there? a. 2 b. 3 c. 5 d. 6 ANSWER BACK TO GAME © 2013 Pearson Education, Inc. Topic 1: Antibodies $100 Answer How many classes of antibodies are there? a. 2 b. 3 c. 5 d. 6 BACK TO GAME © 2013 Pearson Education, Inc. Topic 1: Antibodies $200 Question How many antigen-binding sites do most human antibodies have? a. 1 b. 2 c. 3 d. 4 ANSWER BACK TO GAME © 2013 Pearson Education, Inc. Topic 1: Antibodies $200 Answer How many antigen-binding sites do most human antibodies have? a. 1 b. 2 c. 3 d. 4 BACK TO GAME © 2013 Pearson Education, Inc. Topic 1: Antibodies $300 Question A typical antibody monomer has a. two identical light chains and two identical heavy chains. b. two different light chains and two different heavy chains. c. two identical light chains and two different heavy chains. d. two different light chains and two identical heavy chains. ANSWER BACK TO GAME © 2013 Pearson Education, Inc. Topic 1: Antibodies $300 Answer A typical antibody monomer has a. two identical light chains and two identical heavy chains. a. two different light chains and two different heavy chains. a. two identical light chains and two different heavy chains. a. two different light chains and two identical heavy chains. BACK TO GAME © 2013 Pearson Education, Inc. Topic 1: Antibodies $400 Question Generally, antibodies recognize and interact with specific regions on antigens called a. binding sites. b. haptens. c. epitopes. d. active sites. ANSWER BACK TO GAME © 2013 Pearson Education, Inc. Topic 1: Antibodies $400 Answer Generally, antibodies recognize and interact with specific regions on antigens called a. binding sites. b. haptens. c. epitopes. d. active sites. BACK TO GAME © 2013 Pearson Education, Inc. Topic 1: Antibodies $500 Question The stem of the Y-shaped antibody monomer is called the ____ region. a. constant b. Fc c. variable d. active ANSWER BACK TO GAME © 2013 Pearson Education, Inc. Topic 1: Antibodies $500 Answer The stem of the Y-shaped antibody monomer is called the ____ region. a. constant b. Fc c. variable d. active BACK TO GAME © 2013 Pearson Education, Inc. Topic 2: Antigens $100 Question Which receptors act as warning flags of an invading organism? a. B cell receptors b. T cell receptors c. Toll-like receptors d. CD4+ receptors ANSWER BACK TO GAME © 2013 Pearson Education, Inc. Topic 2: Antigens $100 Answer Which receptors act as warning flags of an invading organism? a. B cell receptors b. T cell receptors c. Toll-like receptors d. CD4+ receptors BACK TO GAME © 2013 Pearson Education, Inc. Topic 2: Antigens $200 Question An antigenic foreign substance that has a low molecular weight is called a(n) a. allergen. b. hapten. c. antigenic determinant. d. dimer. ANSWER BACK TO GAME © 2013 Pearson Education, Inc. Topic 2: Antigens $200 Answer An antigenic foreign substance that has a low molecular weight is called a(n) a. allergen. b. hapten. c. antigenic determinant. d. dimer. BACK TO GAME © 2013 Pearson Education, Inc. Topic 2: Antigens $300 Question Most antigens are composed of a. proteins or lipids. b. lipids or large polysaccharides. c. nucleic acids or lipids. d. proteins or large polysaccharides. ANSWER BACK TO GAME © 2013 Pearson Education, Inc. Topic 2: Antigens $300 Answer Most antigens are composed of a. proteins or lipids. b. lipids or large polysaccharides. c. nucleic acids or lipids. d. proteins or large polysaccharides. BACK TO GAME © 2013 Pearson Education, Inc. Topic 2: Antigens $400 Question In opsonization, antigens that are coated with antibodies are susceptible to a. B cells. b. T helper cells. c. phagocytosis. d. complement. ANSWER BACK TO GAME © 2013 Pearson Education, Inc. Topic 2: Antigens $400 Answer In opsonization, antigens that are coated with antibodies are susceptible to a. B cells. b. T helper cells. c. phagocytosis. d. complement. BACK TO GAME © 2013 Pearson Education, Inc. Topic 2: Antigens $500 Question IgG antibodies inactivate microbes by blocking their attachment to host cells in the binding process known as a. neutralization. b. agglutination. c. antibody-dependent cell-mediated cytotoxicity. d. opsonization. ANSWER BACK TO GAME © 2013 Pearson Education, Inc. Topic 2: Antigens $500 Answer IgG antibodies inactivate microbes by blocking their attachment to host cells in the binding process known as a. neutralization. b. agglutination. c. antibody-dependent cell-mediated cytotoxicity. d. opsonization. BACK TO GAME © 2013 Pearson Education, Inc. Topic 3: Humoral Immunity $100 Question Approximately how many genes are associated with the diversity of the human immune system for recognizing the vast amount of possible antigens? a. hundreds b. thousands c. millions d. billions ANSWER BACK TO GAME © 2013 Pearson Education, Inc. Topic 3: Humoral Immunity $100 Answer Approximately how many genes are associated with the diversity of the human immune system for recognizing the vast amount of possible antigens? a. hundreds b. thousands c. millions d. billions BACK TO GAME © 2013 Pearson Education, Inc. Topic 3: Humoral Immunity $200 Question What is the activation and proliferation of specific B cells termed? a. plasma cell selection b. clonal expansion c. plasma cell expansion d. clonal selection ANSWER BACK TO GAME © 2013 Pearson Education, Inc. Topic 3: Humoral Immunity $200 Answer What is the activation and proliferation of specific B cells termed? a. plasma cell selection b. clonal expansion c. plasma cell expansion d. clonal selection BACK TO GAME © 2013 Pearson Education, Inc. Topic 3: Humoral Immunity $300 Question Plasma cells are formed after the proliferation of which type of cell? a. B cell b. T cell c. memory cell d. monocyte ANSWER BACK TO GAME © 2013 Pearson Education, Inc. Topic 3: Humoral Immunity $300 Answer Plasma cells are formed after the proliferation of which type of cell? a. B cell b. T cell c. memory cell d. monocyte BACK TO GAME © 2013 Pearson Education, Inc. Topic 3: Humoral Immunity $400 Question A collection of genes that encode molecules of genetically diverse glycoproteins found on mammalian nucleated cells is called the a. complement. b. antibody-complement complex. c. interleukins. d. major histocompatibility complex. ANSWER BACK TO GAME © 2013 Pearson Education, Inc. Topic 3: Humoral Immunity $400 Answer A collection of genes that encode molecules of genetically diverse glycoproteins found on mammalian nucleated cells is called the a. complement. b. antibody-complement complex. c. interleukins. d. major histocompatibility complex. BACK TO GAME © 2013 Pearson Education, Inc. Topic 3: Humoral Immunity $500 Question _____ is the changing of antibody classes without changing the antigenic specificity. a. Class switching b. Clonal selection c. Clonal specificity d. Class selection ANSWER BACK TO GAME © 2013 Pearson Education, Inc. Topic 3: Humoral Immunity $500 Answer _____ is the changing of antibody classes without changing the antigenic specificity. a. Class switching b. Clonal selection c. Clonal specificity d. Class selection BACK TO GAME © 2013 Pearson Education, Inc. Topic 4: Cellular Immunity $100 Question Maturation of the T cells takes place in the a. bone marrow. b. liver. c. thymus. d. spleen. ANSWER BACK TO GAME © 2013 Pearson Education, Inc. Topic 4: Cellular Immunity $100 Answer Maturation of the T cells takes place in the a. bone marrow. b. liver. c. thymus. d. spleen. BACK TO GAME © 2013 Pearson Education, Inc. Topic 4: Cellular Immunity $200 Question Where are MHC II proteins found, and what cells recognize them? a. all body cells; T helper cells b. all body cells; T cytotoxic cells c. APCs; T helper cells d. APCs; T cytotoxic cells ANSWER BACK TO GAME © 2013 Pearson Education, Inc. Topic 4: Cellular Immunity $200 Answer Where are MHC II proteins found, and what cells recognize them? a. all body cells; T helper cells b. all body cells; T cytotoxic cells c. APCs; T helper cells d. APCs; T cytotoxic cells BACK TO GAME © 2013 Pearson Education, Inc. Topic 4: Cellular Immunity $300 Question T cells are classified by certain glycoproteins on their surface called a. granzymes. b. endogenous antigens. c. clusters of differentiation. d. interleukins. ANSWER BACK TO GAME © 2013 Pearson Education, Inc. Topic 4: Cellular Immunity $300 Answer T cells are classified by certain glycoproteins on their surface called a. granzymes. b. endogenous antigens. c. clusters of differentiation. d. interleukins. BACK TO GAME © 2013 Pearson Education, Inc. Topic 4: Cellular Immunity $400 Question Which cells combat autoimmunity as their primary function? a. cytotoxic T lymphocytes b. T cytotoxic cells c. T helper cells d. T regulatory cells ANSWER BACK TO GAME © 2013 Pearson Education, Inc. Topic 4: Cellular Immunity $400 Answer Which cells combat autoimmunity as their primary function? a. cytotoxic T lymphocytes b. T cytotoxic cells c. T helper cells d. T regulatory cells BACK TO GAME © 2013 Pearson Education, Inc. Topic 4: Cellular Immunity $500 Question Cytotoxic T lymphocytes attach to the target cell and release a. lysozymes. b. perforin. c. complement proteins. d. lytic enzymes. ANSWER BACK TO GAME © 2013 Pearson Education, Inc. Topic 4: Cellular Immunity $500 Answer Cytotoxic T lymphocytes attach to the target cell and release a. lysozymes. b. perforin. c. complement proteins. d. lytic enzymes. BACK TO GAME © 2013 Pearson Education, Inc. Topic 5: Adaptive Immunity $100 Question The relative amount of antibody in the serum is referred to as the a. number of B cells. b. differential count. c. antibody titer. d. T cell count. ANSWER BACK TO GAME © 2013 Pearson Education, Inc. Topic 5: Adaptive Immunity $100 Answer The relative amount of antibody in the serum is referred to as the a. number of B cells. b. differential count. c. antibody titer. d. T cell count. BACK TO GAME © 2013 Pearson Education, Inc. Topic 5: Adaptive Immunity $200 Question The antibody that is formed in the secondary response is mostly a. IgG. b. IgE. c. IgM. d. IgA. ANSWER BACK TO GAME © 2013 Pearson Education, Inc. Topic 5: Adaptive Immunity $200 Answer The antibody that is formed in the secondary response is mostly a. IgG. b. IgE. c. IgM. d. IgA. BACK TO GAME © 2013 Pearson Education, Inc. Topic 5: Adaptive Immunity $300 Question A person who has had measles will develop _____ immunity. a. naturally acquired active b. naturally acquired passive c. artificially acquired active d. artificially acquired passive ANSWER BACK TO GAME © 2013 Pearson Education, Inc. Topic 5: Adaptive Immunity $300 Answer A person who has had measles will develop _____ immunity. a. naturally acquired active b. naturally acquired passive c. artificially acquired active d. artificially acquired passive BACK TO GAME © 2013 Pearson Education, Inc. Topic 5: Adaptive Immunity $400 Question A toxoid, such as the tetanus toxoid, conveys _____ immunity. a. naturally acquired active b. naturally acquired passive c. artificially acquired active d. artificially acquired passive ANSWER BACK TO GAME © 2013 Pearson Education, Inc. Topic 5: Adaptive Immunity $400 Answer A toxoid, such as the tetanus toxoid, conveys _____ immunity. a. naturally acquired active b. naturally acquired passive c. artificially acquired active d. artificially acquired passive BACK TO GAME © 2013 Pearson Education, Inc. Topic 5: Adaptive Immunity $500 Question What type of immunity is conveyed when exposed individuals are given antibodies by injection? a. naturally acquired active b. naturally acquired passive c. artificially acquired active d. artificially acquired passive ANSWER BACK TO GAME © 2013 Pearson Education, Inc. Topic 5: Adaptive Immunity $500 Answer What type of immunity is conveyed when exposed individuals are given antibodies by injection? a. naturally acquired active b. naturally acquired passive c. artificially acquired active d. artificially acquired passive BACK TO GAME © 2013 Pearson Education, Inc. FINAL ROUND Question Which antigen-presenting cells play a key role in helping your immune system differentiate self from nonself? a. neutrophils b. dendritic cells c. memory cells d. plasma cells ANSWER BACK TO GAME © 2013 Pearson Education, Inc. FINAL ROUND Answer Which antigen-presenting cells play a key role in helping your immune system differentiate self from nonself? a. neutrophils b. dendritic cells c. memory cells d. plasma cells BACK TO GAME © 2013 Pearson Education, Inc.