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Complex InheritanceExploring More About Genetics The inheritance of biological characteristics is determined by individual units known as genes and genes are passed from parents to their offspring In cases of alleles, some may be dominant, others recessive In most sexually reproducing organisms, each adult has two copies of each geneone from each parent The alleles for different genes usually segregate independently Mendel’s Principles The segregation of one pair of alleles does not affect the segregation of another pair Mendel performed experiments with two different genes (i.e. round/wrinkled and yellow/green) and crossed the hybrids (RrYy) He found that different traits segregate independently during the formation of gametes This forms genetic variability Independent Assortment First introduced by Mendel Used to determine if an individual expresses a homozygous dominant or heterozygous trait It involves breeding the individual with an individual who expresses the recessive version of the trait If all offspring display the dominant phenotype, the individual is homozygous dominant If the offspring display both phenotypes, the individual is heterozygous Test Cross There are exceptions to most of Mendel's principles Not all genes show simple patterns of dominant and recessive alleles-most of the time its much more complicated because most genes have more than two alleles Some traits are controlled by more than one gene Beyond Dominant and Recessive Incomplete dominance- cases in which one allele is not completely dominant over another Codominance- both alleles contribute to the phenotype Multiple alleles- genes that have more than two alleles Polygenic traits- traits controlled by two or more genes Exceptions to the Rule: Vocabulary Incomplete Dominance Example A red 4 o’clock (RR) breeding with a white 4 o’clock (WW), neither red nor white is dominant thus the offspring will be a mixture of the two colors or pink R R W RW pink RW pink W RW pink RW pink In chickens the allele for black feathers is codominant with an allele for white feathers, the heterozygous chickens have a color termed erminette (both color feathers); the two colors appear separately and are not blended Codominance Example It means that there are more than two possible alleles exist in a population Rabbit color is the best known example, it is determined by a single gene that has at least 4 alleles, colors include: ◦ Full color (brownish) ◦ Chinchilla (greyish) ◦ Himalayan (white body, dark colored ears, nose and paws) ◦ Albino (no color, white) Blood type is also considered multiple alleles Multiple Alleles Examples Phenotype Genotype A IAIA or IAi B IBIB or IBi AB IAIB only O ii only Examples of Blood Type Crosses Blood Typing Overview Poly means many so the term mean having many genes Fruit flies have at least three genes involved in making their reddish-brown eye pigment and different combinations of the three genes produces variations in the eye color Eye color, hair color and skin color are also controlled by more than one trait Polygenic Traits Examples True-breeding-plants that self-pollinate creating clones of themselves Hybrid-offspring of crosses between parents with different traits Segregation-separation of alleles Gametes-sex cells Allele-one form of a gene Antigens-substance that prompts the generation of antibodies Glossary