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Chapter 9 Genetics 9.1 The Work of Gregor Mendel • Mendel – crossed pea plants to study and understand genetics – Most pea plants self pollinate (true breeding) – Mendel forced plants to cross pollinate (have 2 plants) – Studied 7 traits of pea plants pg 176. – Took the plants that had different traits and crossbreds them (hybrids) The F1 Cross • First Filial (parent cross, produce the F1, then cross the F1 making an F2) – Law of segregation: Segregation of alleles occurs during the formation of gametes, sex cells. – Pg 177 – Law of Independent Assortment – factors for individual characteristics are not connected. Assort independently of each other. Came to 2 conclusions after the breeding 1. Genes, segment of DNA, occurs in pairs, controll heredity. Visual form called alleles. (noted as “factors”) 2. Found that some of the alleles are dominant and some are recessive. 1. Dominant trait always uppercase (TT, Tt) 2. Recessive always lowercase (tt) 9.2 Probability and Punnett Squares • Punnett square – table representation of crossing alleles – TT or tt – homozygous – same alleles – Tt – heterozygous – different alleles – Phenotype – physical look, all tall (TT, Tt) have same phenotype. – Genotype – based on alleles. (TT, and Tt) are different now. Probability • Penny = ½ = .50 • A cross results in 787 pink flowers and 277 white flowers. If we cross the same P generation, the probability will be the same) • • • • • • • • • • • • • • • • • • • • Dominant Curled Up Nose Clockwise Hair Whorl Can Roll Tongue Widow's Peak Facial Dimples Able to taste PTC Earlobe hangs Middigital hair (fingers) No hitchhiker's thumb Tip of pinkie bends in Oval face Cleft chin Broad eyebrow Separated eyebrows Long eyelashes Almond eyes Freckles Wet-type earwax Left thumb on top of interlocking fingers Recessive Roman Nose Counter-clockwise Hair Whorl Can't Roll Tongue No Widow's Peak No Facial Dimples Unable to taste PTC Earlobe attaches at base No middigital hair Hitchhiker's thumb Pinkie straight Square face no cleft chin Slender eyebrow Joined eyebrows Short eyelashes Round eyes No freckles Dry-type earwax Right thumb on top of interlocking fingers Punnett Squares pg 182 Homozygous x homozygous Homozygous x heterozygous • AA x Aa Hetero x hetero Summary of Mendel’s Principles pg 272 • Some alleles are neither dominant nor recessive, and many traits are controlled by multiples alleles or multiple genes. • Incomplete Dominance – when one allele is not necessarily dominant (red and white flowers produce pink) • Codominance – both alleles contribute to the phenotype. • Multiple alleles – within the population of the species there are more than just 2 types of alleles. Coloration in Rabbits • Polygenic Traits – having many genes, traits controlled by 2 or more genes. Skin color in humans. • Incomplete Dominance • We'll use "F" for the flower color allele. FR = allele for red flowers FW = allele for white flowers red x white ------> red & white spotted flowers FRFR x FWFW ----> 100% FRFW Codominance • Problems Explore Punnett Squares!! • http://www.geocities.com/CapeCanaveral/ Hall/1410/lab-B-19.html Dihybrid cross – two traits