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From whom did you get your traits? • Parents • Mom • Dad What kind of traits do you think you got from your parents? • Eye color • Hair color • Height • Nose shape Which traits do you prefer? What is the next chapter? • A. Ecology • B. Viruses • C. Genetics • D. Plants 10.1 Mendelian Genetics! Pg. 177 What is genetics? • • • • Genetics: Study of heredity and variation in organisms. Heredity: Passing of genetic information from parent to offspring. Traits • Traits: • Variation of a particular character. • Ex. Eye color, hair color, and nose shape. What are some different traits? • Tail length • Hair color • Ear direction • Mendelian Genetics • In the 1800s an Austrian monk studied plants. His name was Gregor Mendel. He is called the “Father of Genetics”. • Mendel wanted to describe how traits were passed between generations. What happens when you cross red with yellow? • Red mixed with yellow makes…. • Orange. • If you crossed a red flower and a yellow flower… what color would the offspring be? • Red and yellow. Mendel’s Experiment • Performed experiments using pea plants. • • • • Why pea plants? Easy to grow Have easy observable traits Reproduce quickly Pea Plant Traits • 1. Flower color • 2. Flower position • 3. Seed color • 4. Seed shape • 5. Pod shape • 6. Pod color • 7. Plant height Mendel’s Experiment • Step 1: • Looked at one trait, the flower color. • Mendel allowed the pea plants to self-pollinate. This gave him purebred plants for the offspring. • Purebred: Genetically uniform (identical). • He called these plants the P generation (Parental). Mendel’s Experiment • Step 2: • Cross-pollinated two P generation plants. • Monohybrid cross: Parent plants differ in one characteristic. • Flowers were all purple. He called these plants the F1 generation. F1 generation is the offspring of the P generation. Mendel’s Experiment • Step 3: • Allowed F1 generation to self-pollinate. • Produced a mix of white and purple flowers. He called this generation the F2 generation. Mendel kept growing pea plants! Overall 10.2 Inheritance Theory • For each inherited characteristic an individual has 2 copies of a gene. • These copies are called alleles. • Alleles are represented by letters. • Ex. PP or Pp or pp Alleles • Dominant alleles: • Will always be expressed with 1 or 2 uppercase letters. • Ex. PP or Pp • Recessive alleles: • Will only be expressed with 2 lowercase letters. • Ex. pp Let’s Try • Ex. Flower color • Purple is dominant to white. • What color is PP? • Purple • What color is pp? • White • What color is Pp? • Purple Vocabulary • Homozygous: • When the alleles are the same. • Homozygous Dominant: • Alleles are both uppercase letters. Ex. PP or BB • Homozygous Recessive: • Alleles are both lowercase letters. Ex. pp or bb • Heterozygous: • Different. One uppercase and one lowercase letter. • Ex. Pp or Bb Genotype/Phenotype Genotype: Genetic makeup of an organism. Ex. PP or Pp or pp Phenotype: Physical characteristic expressed from the genotype. • Ex. Purple, purple, white • • • • • Mendel's First Law • Law of Segregation: • Organism inherits two copies of genes, one from each parent. Alleles are separated during gamete formation. Punnett Squares • Diagram that shows the probabilities of the possible outcome of a genetic cross. Your mother is homozygous for black hair and your dad has blonde hair. Black is dominant to blonde. Testcross • What is the genotype of an organism that displays the dominant phenotype? • Let’s say purple flower color. And we use the allele P. • PP or Pp • How can we figure out if the organism is PP or Pp? Perform a Testcross using Punnett Square • What would the other organism’s genotype and phenotype be? • Would have to use pp and white color flower. Mendel's Second Law • Law of Independent Assortment: • Alleles for different genes separate independently of one another during gamete formation. • Dihybrid cross: • Crossing organisms differing in two characteristics. • Mendel crossed a true-breeding plant with round yellow seeds (RRYY) with a true-breeding plant grown from wrinkled green seeds (rryy) • What would the offspring's phenotype be? • All round and yellow. • He then self pollinated the offspring. 10.3 Variations of Inheritance • What is the offspring when you cross a Black chicken with a White chicken? • • Blue chicken x • This is called intermediate inheritance or incomplete dominance. • Intermediate inheritance: • Inheritance in which heterozygotes have an intermediate phenotype. Neither phenotype is expressed in offspring. P RR x rr F1 Rr x Rr F2 1 RR 2 Rr 1 rr Multiple Alleles • Codominance: • Both dominant alleles are expressed. • For example blood. What are the four blood types? • • • • A B AB O ABO Blood Alleles IA – dominant allele for type A blood IB – dominant allele for type B blood i – recessive allele for type O blood ABO Blood Grouping Blood type Genotype A IAIA or IAi B IBIB or IBi AB IA IB O ii NOTE: Blood type AB is also an example of codominance Polygenic Inheritance • Polygenic inheritance: • Multiple genes affect a characteristic, the variation in phenotypes can become greater. • Example. • Humans height and skin color. Importance of Environment • If a woman who is 6 ‘3’ and mates with a male who is 6 ‘7’… does that mean their son or daughter will be tall? Why? • No, their offspring could be malnourished. • Think of plants. Depending of the plant gets sunlight and water it affects how it will grow. • Think of professional athletes and their parents. Environment • Temperature can also effect the phenotype. Siamese cats usually have white fur but when there is cooler temperatures it changes the cats enzyme which makes the coat color darker. 10.4 Meiosis Explains Mendel’s Principles • Chromosomes theory of inheritance: • States that genes are located on chromosomes, and the behavior of chromosomes during meiosis and fertilization accounts for inheritance patterns. • All advanced organisms have chromosomes. Half the chromosomes comes from the father and half from the mother. Genetic Linkage and Crossing Over • When genes are located on separate chromosomes, they sort independently of each other. • When genes are located close to each other the greater the genetic linkage. • Genetic linkage: • The tendency for the alleles on one chromosome to be inherited together. 10.5 Sex-linked traits • Humans have 23 pairs of chromosomes. • One set of chromosomes are called sex chromosomes. • If you are XX you are a female. • XY you are a male. Chromosomes Sex Linked Genes • Any gene that is located on the sex chromosome is called sex linked gene. • In humans most sex linked genes are located on the X chromosome because it is much bigger than the Y chromosome. Colorblindness • Colorblindness is inherited as sex linked X recessive traits. XB Xb Xb XB Xb Xb Xb Y XB Y Xb Y WHAT NUMBERS DO YOU SEE? WHAT NUMBERS DO YOU SEE? WHAT NUMBERS DO YOU SEE? NOW WHAT NUMBER DO YOU SEE???