Download DNAMocktst

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Review all terms on your word lists.
Be familiar with the basics of nucleic acids
Know the contributions of the following
scientists to DNA knowledge: Watson &
Crick, Franklin, Griffith, Levene, Meischer,
Avery, MacLeod, McCarty, Hershey & Chase
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You should know the four bases found in DNA
and understand Chargaff’s rule.
Know what nucleotides are and what they are
composed of.
Understand the differences between purines
and pyrimidines
Understand DNA replication and understand
the basic steps in DNA replication. (overview
sheet like pg.222
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Know why DNA replication is called semiconservative replication. You should know
what enzymes are important in DNA
replication and the role that these enzymes
play in DNA replication. Review the chart on
Enzymes involved with replication.
Diagrams to be able to label: DNA replication
pg.222 and DNA nucleotide pg.210
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Contributions of Garrod, Beadle & Tatum, Ingram
List the differences bt. DNA & RNA
Review one gene- one enzyme theory
Notes on Post –transcriptional modifications
Notes on mutations – be able to recognize diagrams
Review HW questions
Be able to use a codon chart to decode from a given
DNA strand to the final amino acids - mRNA, tRNA,
etc
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MC -.
Short Answer –
Long answer–Including protein
synthesis/mutation question
Diagrams (wordbank provided)
1.
2.
3.
What year was the current DNA model
discovered?
What two scientists are credited with
discovering the shape of DNA?
What scientist isolated nuclear material and
named it nucleic acid?
4.
5.
6.
7.
Who discovered the nucleotide made of 3
parts?
He was researching bacteria and stumbled
on a transforming agent.
What three scientists eventually identified
the transforming agent ?
What was the mystery transforming agent?
What is Chargaff’s rule?
9. The 2 scientists who used viruses to show
it’s DNA that transmits genetic info.
10. She produced an x-ray photograph used to
identify DNA’s structure.
11. He showed this photograph to Watson and
Crick.
12. What are the 4 nitrogen bases in DNA?
8.
Nitrogen bases containing a single ring
structure.
14. Nitrogen bases containing a double ring
structure
15. What 2 molecules form the backbone of DNA?
16. What makes DNA unique from all other organic
molecules?
17. This molecule is located at the 5’ end of DNA.
18. This molecule is located at the 3’ end of DNA.
19. What is a nucleotide composed of?
13.
How many hydrogen bonds are found between
A and T?
21. How many hydrogen bonds are found between
G and C?
22. Where do free floating nucleotides come from?
23. Why is replication referred to as semiconservative?
24. When replication is finished what are the two
new strands called?
25. This enzyme controls the replication of DNA.
26. This enzyme unravels DNA during replication.
20.
Where DNA is still joined after being unwound.
This enzyme relieves tension as DNA unwinds
This enzyme joins the gaps in the Okazaki
fragments.
30. This enzyme lays down RNA primers at the
starting point.
31. Short fragments of DNA built along the lagging
strand.
32. These enzymes double check for mistakes in
replication.
27.
28.
29.
Synthesis of DNA happens in this direction.
34. Strand of DNA built continuously toward
the replication fork.
35. Strand of DNA built discontinuously toward
away from the replication fork.
36. Thymine is replaced by this nitrogen base in
RNA.
37. In this process DNA transfers its code to
mRNA.
33.
38.
39.
40.
41.
42.
43.
This type of RNA delivers the amino acids to the
ribosome.
This type of RNA is a structural component of the
ribosomes.
Two terms for a sequence of 3 nucleotides that
forms a code.
Where is the anticodon located?
In this process the mRNA is read to determine the
protein structure.
What signals the end of protein synthesis?
44.
45.
46.
47.
48.
49.
50.
Name any 2 posttranscriptional modifications.
This type of mutation will have no effect (goes unnoticed).
These mutations occur at specific points in the gene
These mutations are caused by an error of the genetic
machinery.
These mutations are the result of chemical agents or
radiation.
Name 3 examples of mutagenic agents.
The central dogma of molecular genetics consists of DNA
(replication) leading to RNA(transcription) leading to ??
DNA
TAC
AAT
TCG
mRNA
Amino acid
tRNA