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Cellular Respiration Homework Objectives Know the chemical formula for three-stage cellular respiration Know the differences between cellular respiration and photosynthesis: What kinds of organisms perform them Where in the cell they happen Inputs Outputs Energy movement ATP and glucose’s roles Photosynthesis Review Summarize the main points of chemical batteries and photosynthesis in a paragraph. Aerobic Respiration Recall that aerobic respiration uses oxygen. After glycolysis, some cells (humans included) can put the pyruvate through two aerobic respiration stages. Aerobic respiration charges more ATP than anaerobic respiration. Cellular Respiration Break down glucose, get energy… what’s the rest? C6H12O6 + _____ -> ____ + ____ + energy Cellular Respiration C6H12O6 + 6O2 -> 6CO2 + 6H2O + energy What was the equation for photosynthesis again…? Cellular Respiration Glucose is broken down in three stages, each of which captures some of the stored energy and uses it to make some ATP molecules. Not all organisms do all 3 stages all the time. These are the “normal” stages for heterotrophs like us, we’ll talk last about other ways to do it. http://www.qcc.cuny.edu/BiologicalSciences/F aculty/DMeyer/respiration.html Three stages: Glycolysis Krebs Cycle Electron Transport Chain Glycolysis Where glycolysis happens: What goes into glycolysis: What comes out of glycolysis: Krebs Cycle Also called Citric Acid Cycle. The Krebs Cycle happens in the mitochondria. If it only happens in mitochondria, which organisms cannot do the Krebs Cycle? QuickTime™ and a decompressor are needed to see this picture. QuickTime™ and a decompressor are needed to see this picture. Krebs Cycle The Krebs Cycle happens in the mitochondria. Only eukaryotes can do it. Krebs Cycle breaks pyruvic acids down into CO2. Remember, energy is released when bonds are broken. This energy charges more ATP and NADH batteries. Krebs Cycle Breaks down 2 pyruvates (3 carbons each) into 6 CO2 Charges 6 total ATP. (These ATP charges are not all just from ATP, but are the equivalents of an ATP. Each NADH, for instance, holds two times as much energy as an ATP, so we’ll count it as just “2 ATP” to make things easier.) Krebs Cycle http://www.youtube.com/watch?v=lvoZ2 1P4JK8 http://www.johnkyrk.com/krebs.html The charged ATP is used to power cellular activities. It also charges other chemical batteries, which carry that energy to the next stage… Electron Transport Chain Electron Transport Chain (E.T.C.) happens along membranes inside the mitochondria. QuickTime™ and a decompressor are needed to see this picture. QuickTime™ and a decompressor are needed to see this picture. Electron Transport Chain http://www.johnkyrk.com/mitochondrion.ht ml http://highered.mcgrawhill.com/sites/0072437316/student_view0/c hapter9/animations.html# ETC takes the energy from chemical batteries charged in the Krebs Cycle and glycolysis, and charges 24 ATP with it. Electron Transport Chain The electron transport chain works by taking energetic electrons from charged batteries like NADH and FADH2, which depowers them back to NAD+ and FAD. These electrons are given to proteins embedded in the membranes inside the mitrochondria. The proteins use the energy they’ve received to move protons across the membrane, out of the matrix. Electron Transport Chain The protons are now highly concentrated in the intermembrane space and not concentrated in the matrix, and they want to reach equilibrium again. Another protein in the membrane called ATP synthase lets them do that, using their movement like a water wheel uses water. Electron Transport Chain The protons moving down along the ATP synthase to get back where they started “turns the wheel,” which churns out ATPs. At the end, oxygen gets rid of the low-energy electrons that are left over, combining with hydrogen ions to make water. Water = electron transport chain waste product. Cellular Respiration http://www.qcc.cuny.edu/BiologicalSciences/ Faculty/DMeyer/respiration.html Cellular respiration charges 36 ATP total using the energy in one glucose. _______ + ____ -> _____ + _____ + 36 ATP Cellular Respiration Review Summary sentence of aerobic cellular respiration: Stage 1: Stage 2: Stage 3: Cellular Respiration Review Cellular respiration is breaking down glucose to get energy. Glycolysis (in the cytoplasm) Glucose (C6H12O6) broken down into two three-carbon molecules, pyruvic acid. Charges some batteries: 6 ATP and some medium-sized “bad” batteries that go to Electron Transport Chain. Krebs Cycle (in mitochondria) The 2 pyruvic acids are broken down into 6 CO2. Charges some batteries: 6 ATP and some medium-sized “bad” batteries that go to Electron Transport Chain. Electron Transport Chain (in mitochondria) Medium-sized “bad” batteries are decharged, that energy charges 26 ATP. Other pathways A final word: Glucose is not the only way to get and store energy. Other things we eat that we might get energy from? Other pathways Pyruvic acid can be converted back into glucose or glycogen, but once you’re in the Krebs cycle, you can’t go back. Lipids, glycogen, protein are other long-term energy molecules besides glucose. Glycogen is a chemical battery, stores energy long-term in the liver. Can be an alternative outcome instead of going through glycolysis to get pyruvic acid. Lipids are good for storing energy, proteins not so much. Glucose energy can be stored as a lipid, instead of going through the Krebs cycle and electron transport. Proteins aren’t good for storage, but they can be broken down for energy if needed.